Presentation by ICOS DG Werner Kutsch at the UNFCCC Earth Information Day in UN COP22 on Tue 8 November 2016.
See the Earth Information Day programme: http://unfccc.int/science/workstreams/items/9949.php
Short Update on ICOS ERIC by ICOS ERIC Director General Werner Kutsch at the 2nd ICOS Science Conference 2016 in Helsinki, Finland, 27-29 September 2016.
Short Update on ICOS ERIC by ICOS ERIC Director General Werner Kutsch at the 2nd ICOS Science Conference 2016 in Helsinki, Finland, 27-29 September 2016.
C6.05: New ocean-colour products for the user community - Shubha Sathyendrana...Blue Planet Symposium
The ocean-colour component of the Climate Change Initiative of the European Space Agency has generated a time series of bio-optical products from late 1997 to mid 2012. The products are based on data from SeaWiFS, MODIS-A and MERIS sensors, band shifted (to bring data to a common set of wavebands), corrected for inter-sensor bias, and then merged. Products include remote-sensing reflectances at SeaWiFS wavelengths, chlorophyll concentration, diffuse attenuation coefficient at 490 nm, and inherent optical properties (components of absorption and back-scattering coefficients). Practically all the products have uncertainties (root-mean-square difference and bias) associated with them on a pixel-by-pixel basis, based on validation using in situ data. The first version of the products are available freely at www.oceancolour.org and at www.esa-oceancolour-cci.org. A second version is expected to be released prior to the Blue Planet Symposium in Australia in 2015. Furthermore, plans are underway to add to the product suite through a number of related ESA projects. New products envisaged include primary production, photosynthesis parameters, components of the carbon pool in the ocean and photosynthetically active radiation (PAR) at the sea surface. User consultation and serving the user community are very much a part of these projects, and the Blue Planet provides a useful forum for reaching users from a variety of backgrounds. The work reported here contribute to components C2 (Sustained Ecosystems and Food Security) and C5 (Ocean Climate and Carbon) of the “Oceans and Society: Blue Planet” initiative of the Group on Earth Observations (GEO).
C6.05: New ocean-colour products for the user community - Shubha Sathyendrana...Blue Planet Symposium
The ocean-colour component of the Climate Change Initiative of the European Space Agency has generated a time series of bio-optical products from late 1997 to mid 2012. The products are based on data from SeaWiFS, MODIS-A and MERIS sensors, band shifted (to bring data to a common set of wavebands), corrected for inter-sensor bias, and then merged. Products include remote-sensing reflectances at SeaWiFS wavelengths, chlorophyll concentration, diffuse attenuation coefficient at 490 nm, and inherent optical properties (components of absorption and back-scattering coefficients). Practically all the products have uncertainties (root-mean-square difference and bias) associated with them on a pixel-by-pixel basis, based on validation using in situ data. The first version of the products are available freely at www.oceancolour.org and at www.esa-oceancolour-cci.org. A second version is expected to be released prior to the Blue Planet Symposium in Australia in 2015. Furthermore, plans are underway to add to the product suite through a number of related ESA projects. New products envisaged include primary production, photosynthesis parameters, components of the carbon pool in the ocean and photosynthetically active radiation (PAR) at the sea surface. User consultation and serving the user community are very much a part of these projects, and the Blue Planet provides a useful forum for reaching users from a variety of backgrounds. The work reported here contribute to components C2 (Sustained Ecosystems and Food Security) and C5 (Ocean Climate and Carbon) of the “Oceans and Society: Blue Planet” initiative of the Group on Earth Observations (GEO).
Study of the concepts of group organizational dynamics at Baxter India Ltd. The study was conducted by collecting primary and secondary data from various sources and understanding how the organization manages its human resources using concepts of group and organization dynamics. During the course of study we found that the organization follows a rather flat structure which fosters open communication thereby encouraging functional conflicts and open dialogue.
Linking EUDAT services to the EGI Fed-Cloud - EUDAT Summer School (Hans van P...EUDAT
The main goal of the EGI-EUDAT collaboration is to harmonise the two eInfrastructures, including technical interoperability, authentication, authorisation and identity management, policy and operations. As main objective, this work is to provide end-users with a seamless access to an integrated infrastructure offering both EGI and EUDAT services and then, pairing data and high-throughput computing resources together. Selected user communities are able to bring requirements and help assign the right priorities to each of them. In this way, the integration activity has been driven by the end users from the start. The use case permits a user of either e-infrastructure to instantiate a VM on the EGI Cloud Federation for the execution of a computational job consuming data preserved onto EUDAT resources. The results of such analysis can be staged back to EUDAT storages, and if needed, allocated with Persistent identifiers (PIDs) for future use. To implement all the steps of this use case the following integration activities between the two infrastructures has to be fulfilled: (1) harmonisation between the authentication and authorisation model, (2) definition and implementation of the interfaces between the involved EGI and EUDAT services.
Visit: https://www.eudat.eu/eudat-summer-school
RPN Manila 2022: Session 2.6 Raffaele della Croce OECD.pdfOECD Environment
This presentation was delivered during the 6th Meeting of the OECD Southeast Asia Regional Programme’s Regional Policy Network on Sustainable Infrastructure, which took place on 25-26 April 2022 in Manila, the Philippines. The OECD’s Public Governance Directorate and Environment Directorate teamed up with the OECD Korea Policy Centre to organise the event. The National Economic and Development Authority (NEDA) of the Philippines co-chaired the event alongside the United States, and the Public Private Partnership Centre of the Philippines graciously provided the venue. For more details about the meeting, including the agenda and a short summary record, please visit: https://www.oecd.org/site/sipa/events/sipa-searp-philippines-2022.htm.
The NextGEOSS project, a European contribution to GEOSS (Global Earth Observation System of Systems), proposes to develop the next generation data hub for Earth Observations, where the users can connect to access data and deploy data-driven applications.
Presentation by Martial Bernoux, Natural Resources Officer for the Climate and Environment Division of the FAO, Rome. The presentation was part of the Webinar on Soil carbon in the Nationally Determined Contributions hosted by CCAFS, the German Ministry of Food and Agriculture, and the 4 Per Mille Initiative and held on Earth Day, 22 April 2020.
Copernicus Atmosphere Monitoring Service - An introductionCopernicus ECMWF
Copernicus Atmosphere Monitoring Service: An introduction by
Vincent-Henri Peuch, Head of Copernicus Atmosphere Monitoring Service provided for the ECMWF Copernicus Services Info Day, Brussels, 2 February 2015.
Introduction to Day 2 of VNN peatland workshop focused on "Developing a roadmap for peatland GHG accounting and carbon markets in the UK" (19th January 2012, Leeds)
Solving advanced research problems with real time open data from satellites a...Wolfgang Ksoll
The project NextGEOSS brings wit its data hub based on CKAN and its 10 pilot programs a new quality in the usage of earth observation open data from satellites and in situ.
''Copernicus for sustainable land management'' by Markus Erhard, European Environment Agency (EEA)
Sustainable Land Management Session - EU Space Week 2018, Marseille
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...Ana Luísa Pinho
Functional Magnetic Resonance Imaging (fMRI) provides means to characterize brain activations in response to behavior. However, cognitive neuroscience has been limited to group-level effects referring to the performance of specific tasks. To obtain the functional profile of elementary cognitive mechanisms, the combination of brain responses to many tasks is required. Yet, to date, both structural atlases and parcellation-based activations do not fully account for cognitive function and still present several limitations. Further, they do not adapt overall to individual characteristics. In this talk, I will give an account of deep-behavioral phenotyping strategies, namely data-driven methods in large task-fMRI datasets, to optimize functional brain-data collection and improve inference of effects-of-interest related to mental processes. Key to this approach is the employment of fast multi-functional paradigms rich on features that can be well parametrized and, consequently, facilitate the creation of psycho-physiological constructs to be modelled with imaging data. Particular emphasis will be given to music stimuli when studying high-order cognitive mechanisms, due to their ecological nature and quality to enable complex behavior compounded by discrete entities. I will also discuss how deep-behavioral phenotyping and individualized models applied to neuroimaging data can better account for the subject-specific organization of domain-general cognitive systems in the human brain. Finally, the accumulation of functional brain signatures brings the possibility to clarify relationships among tasks and create a univocal link between brain systems and mental functions through: (1) the development of ontologies proposing an organization of cognitive processes; and (2) brain-network taxonomies describing functional specialization. To this end, tools to improve commensurability in cognitive science are necessary, such as public repositories, ontology-based platforms and automated meta-analysis tools. I will thus discuss some brain-atlasing resources currently under development, and their applicability in cognitive as well as clinical neuroscience.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
This presentation explores a brief idea about the structural and functional attributes of nucleotides, the structure and function of genetic materials along with the impact of UV rays and pH upon them.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
Unveiling the Energy Potential of Marshmallow Deposits.pdf
The GEO initiative on Carbon and Greenhouse Gases: Integration across domains
1. The GEO initiative on
Carbon and Greenhouse Gases:
Integration across domains
Werner L. Kutsch, Director General, ICOS ERIC
UNFCCC EarthInfoDay, Marrakech, 8. November 2016
2. 2
The top-down
atmospheric
approach
Simulation of
Column CO2 emissions
plumes
Simulation of total column CO2 (XCO2)
over Europe 20 Mar – 30 Apr 2008 at
7 km x 7 km resolution
Animation by Dominik Brunner (Empa),
model simulation by Yu Liu and Nicolas Gruber (ETH)
8. Data sharing
Data management (incl. metadata)
Capacity building
Improve data harmonization
Improve inter-operability
Improve data accessibility
Data Citation
From data to
knowledge
Model-Data
Fusion
projects
SustainabilityIdentifying observational gaps
Communication
SBSTA
Observations Services Knowledge Decisions
2
1
3 4
From Observations to Decisions
9. Activities of the GEO Carbon and GHG Initiative
Task 1 – User needs and policy interface:
to engage with users and policy makers and ensure the consistency
with their evolving needs in order to drive the activities of the GEO
Carbon and GHG Initiative and address the policy agenda.
Task 2 – Data access and availability:
to provide long-term, high quality and open access near-real-time
data and data products, complying with the GEOSS principles, from a
domain-overarching carbon cycle and GHGs monitoring system.
Task 3 – Optimization of observational networks:
to develop and implement a procedure for achieving observations of
identified essential carbon cycle variables within user-defined
specifications and at minimum total cost.
Task 4 –Budget calculations and breakdown across scales:
To support the development of consistent budgets of GHGs (CO2,
CH4, and N2O) across scales using a combination of observations,
inventories, models and data assimilation techniques.
2
1
3
4
10. GEO-XII Plenary & Ministerial Summit
Mexico City 9-13 November 2015
• Ministerial Declaration that focuses on harnessing critical
environmental observations
• Adoption of a ten year Strategic Plan (2016-2025)
“GEO will supply the requisite Earth observations in
support of effective policy responses for climate change
adaptation, mitigation and other impacts across the SBAs.”
11. New Societal Benefit Areas (SBAs)
Climate change and its impacts cut across all SBAs
12. Background of the GEO Carbon and GHG Initiative
“Improve the inter-operability
with other carbon observation
systems, contributing to the
new GEO Strategy and the new
GEO 10 years Implementation
Plan (IP) for 2016-2025.”
“This report, the CEOS Strategy for
Carbon Observations from Space, is a
response from the Committee on
Earth Observation Satellites (CEOS) to
the GEO Carbon Strategy. It details
the adequacy of past, present, and
planned satellite measurements of
carbon in the land, oceans and inland
waters, and atmosphere domains to
support GEO…”
“GEO through its Members and
Participating Organizations, has
begun work to implement a global
carbon observation and analysis
system addressing the three
components of the carbon cycle
(atmosphere, land and ocean) to
provide high quality information on
carbon dioxide (CO2) and methane
(CH4) concentrations, and emission
variations.”
1
14. Measurement stations
(National networks)
ICOS Carbon Portal
User 1 User 2 User 3
Ecosystem
Thematic
Centre
Atmospheric
Thematic
Centre
Oceanic
Thematic
Centre
Standardized
processing, quality
assurance & control
ICOS
repository
(data,
metadata)
Sensor data
• Data ingestion
• Metadata services
• Data discovery & access
• Usage tracking
• Data management
• Repository
administration
• Preservation planning
• User community support
Diverse user
communities, including
data producers and
other portals
High per-
formance
computing
services
Finalized
data products
Metadata
registry &
catalogue
services
B2SAFE
B2STAGE
PID
PID, AAI
B2FIND
PID
AAI
Calibration
Labs
The Data life cycle of ICOS
2
15. Dr. habil. Werner L Kutsch, werner.kutsch@icos-ri.eu, www.icos-ri.eu
Task 2 – Data access and availability: the GEO workflow
2
16. Task 3 – Optimization of observational networks:
Closing spatial observational gaps
Supporting new technologies and concepts
Translating user needs to observational concepts.
Dr. habil. Werner L Kutsch, werner.kutsch@icos-ri.eu, www.icos-ri.eu
3
17. Features of the GEO Carbon and GHG Initiative
A framework / platform for cooperation
that is seeking integration across domains.
Builts on existing infrastructures
and supports their efforts to cooperate.
Providing opportunities
to optimize the data fabric from observations to decisions,
to identify geographical or conceptual gaps,
to gather additional resources from member countries.
Not running in parallel or duplicating other efforts
but seeking cooperation and communication.
Dr. habil. Werner L Kutsch, werner.kutsch@icos-ri.eu, www.icos-ri.eu
18. THANK YOU FOR YOUR ATTENTION!
Dr. habil. Werner L Kutsch, werner.kutsch@icos-ri.eu, www.icos-ri.eu