The document summarizes the CASCADE project, a collaborative research project investigating catastrophic shifts in dryland ecosystems. The project involves field experiments and modeling across 6 Mediterranean sites to better understand the mechanisms underlying sudden regime shifts in drylands. The goals are to develop indicators of proximity to tipping points to inform more sustainable land management practices, prevent major losses of biodiversity and ecosystem services, and make policy recommendations. The project is expected to advance scientific knowledge of dryland functioning and tipping points, as well as develop land use practices to preserve ecosystems and inform policymakers.