Residual damage to heart valves following recurrent ARF
Valves become scarred, stiff, thickened
Blood leaks (blood flows backwards through valves which do not close properly)
Blood is blocked (blood can not flow through valves which do not open properly)
Complications of Fracture by Dr. Urvish Bhanushali(JR1,Dept of Orthopedics,GS...Dr.Urvish Bhanushali
Presentation on Complications of Fracture. Provides a brief overview on various complications and is useful to present as a seminar as well as to learn quickly. Content is being taken from Standard books as well as online.
Residual damage to heart valves following recurrent ARF
Valves become scarred, stiff, thickened
Blood leaks (blood flows backwards through valves which do not close properly)
Blood is blocked (blood can not flow through valves which do not open properly)
Complications of Fracture by Dr. Urvish Bhanushali(JR1,Dept of Orthopedics,GS...Dr.Urvish Bhanushali
Presentation on Complications of Fracture. Provides a brief overview on various complications and is useful to present as a seminar as well as to learn quickly. Content is being taken from Standard books as well as online.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
CDSCO and Phamacovigilance {Regulatory body in India}NEHA GUPTA
The Central Drugs Standard Control Organization (CDSCO) is India's national regulatory body for pharmaceuticals and medical devices. Operating under the Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India, the CDSCO is responsible for approving new drugs, conducting clinical trials, setting standards for drugs, controlling the quality of imported drugs, and coordinating the activities of State Drug Control Organizations by providing expert advice.
Pharmacovigilance, on the other hand, is the science and activities related to the detection, assessment, understanding, and prevention of adverse effects or any other drug-related problems. The primary aim of pharmacovigilance is to ensure the safety and efficacy of medicines, thereby protecting public health.
In India, pharmacovigilance activities are monitored by the Pharmacovigilance Programme of India (PvPI), which works closely with CDSCO to collect, analyze, and act upon data regarding adverse drug reactions (ADRs). Together, they play a critical role in ensuring that the benefits of drugs outweigh their risks, maintaining high standards of patient safety, and promoting the rational use of medicines.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
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5. ANATOMY OF VESSELS
RETINAL ARTERIOLES-EXHIBIT AUTOREGULATORY MECHANISMS AND TIGHT
JUNCTIONS TO MAINTAIN BLOOD OCULAR BARRIER
CHOROIDAL ARTERIOLES-HAVE FENESTRATIONS
OPTIC NERVE –HEAD VESSELS EXHIBIT INTERMEDIARY
CHARACTERISTICS WITH AUTOREGULATION
HYPERTENSION
LONGTERM MEDICAL CONDITION IN WHICH BLOOD PRESSURE IN
ARTERIES IS PERSISTENTLY ELEVATED
9. .VASOCONSTRICTION - PRIMARY RESPONSE OF RETINAL
ARTERIOLES TO RAISED BP IS NARROWING
• RELATED TO SEVERITY OF HTN
• ARTERIOSCLEROTIC CHANGES - REFLECTS THE DURATION
OF HTN; RESULTS FROM THICKENING OF VESSEL WALL &
MANIFEST AS CHANGES IN ARTERIOLAR LIGHT REFLUX & A-V
NICKING
• INCREASED VASCULAR PERMEABILITY- RESULTS FROM
HYPOXIA
• RESPONSIBLE FOR HEAMORRHAGES , EXUDATES & RETINAL
OEDEMA
10.
11. CLINICAL TYPES
• FUNDUS CHANGES CAN BE DESCRIBED AS
• 1) CHRONIC HYPERTENSIVE RETINOPATHY
• 2) MALIGNANT OR
ACUTE HYPERTENSIVE RETINOPATHY
12. CLINICAL TYPES
• CHRONIC HYPERTENSIVE
RETINOPATHY
* HTN WITH SENILE SCLEROSIS
* HTN WITH OUT SCLEROSIS
* HTN WITH COMPENSATORY
ARTERIOSCLEROSIS
13. HTN WITH SENILE SCLEROSIS
• HTN WITH SENILE SCLEROSIS
• ELDERLY (>50)
• FUNDUS- AUGMENTED ARTERIOSCLEROTIC RETINOPATHY
• HTN WITH OUT SCLEROSIS
• YOUNG
• EXPOSURE TO RAISED BP FOR A SHORT DURATION
• NO RETINAL SIGNS
• NO PAPILLOEDEMA / EXUDATES
14. HTN WITH COMPENSATORY ARTERIOLAR
SCLEROSIS
• YOUNG INDIVIDUALS
• PROLONGED BENIGN HTN ASS. ALONG BENIGN
NEPHROSCLEROSIS
• PROLIFERATIVE & FIBROUS CHANGES IN MEDIA
• FUNDUS CHANGES HAVE BEEN DESCRIBED AS
ALBUMINURIC OR RENAL RETINOPATHY
15. FUNDUS CHANGES IN CHRONIC
HYPERTENSIVE RETINOPATHY
• GENERALISED ARTERIOLAR NARROWING
• FOCAL ARTERIOLAR NARROWING
• SUPERFICIAL RETINAL HEAMORRHAGE(FLAME SHAPED)
• HARD EXUDATES – YELLOWISH WAXY SPOTS , ARRANGED IN
MACULAR FAN OR MACULAR STAR
• COTTON WOOL SPOTS – SOFT EXUDATES
16. ARTERIOLAR REFLUX CHANGES
• A) BRIGHT AND THIN , LINEAR BLOOD REFLEX-IN NORMAL CONDITION
• B) MORE DIFFUSE AND LESS BRIGHT REFLEX- DUE TO VESSEL WALL
THICKENING
• C)COPPER WIRING- REDDISH BROWN REFLEX DUE TO PROGRESSIVE
SCLEROSIS AND HYALINISATION
• D)SILVER WIRING- OPAQUE WHITE REFLEX , DUE TO CONTINUED
SCLEROSIS
19. AV NICKING
• A) SALU’S SIGN- DEFLECTION OF VEINS AT THE ARTERIO VENOUS CROSSING
• B) BONNET SIGN- BANKING OF VEINS DISTAL TO AV CROSSING
• C) GUNN SIGN – TAPPERING OF VEINS ON EITHER SIDE OF THEIR CROSSING
24. STAGING
• KEITH AND WAGNER CLASSIFICATION
• SCHEIE CLASSIFICATION
• WONG AND MC INTOSH CLASSIFICATION
25.
26.
27. MANAGEMENT
• MILD HYPERTENSIVE RETINOPATHY
• --- REQUIRES BLOOD PRESSURE CONTROL
ONLY
• MODERATE HYPERTENSIVE RETINOPATHY
• ----PATIENT IN ADDITION TO BP CONTROL
BENEFIT FROM FURTHER ASSESSMENT OF VASCULAR RISK FACTORS
AND IT INDICATE RISK REDUCTION THERAPY
• ACCELERATED HYPERTENSIVE RETINOPATHY
• ----NEED URGENT ANTI HYPERTENSIVE
MANAGEMENT
28. PREGNANCY INDUCED HTN
• KNOWN AS TOXAEMIA OF PREGNANCY ,IS A DISEASE OF
UNKNOWN ETIOLOGY CHARACTERISED BY RAISED BP,
PROTEINURIA AND GENERALISED OEDEMA
• RETINAL CHANGES---- LIABLE TO ACCESS WHEN BP>160/100 mm of
Hg
• ----MARKED WHEN > 200/130 mm of Hg
29. PREGNANCY INDUCED HTN
MANAGEMENT
• IN PREORGANIC STAGE WHEN PATIENT RESPOND WELL TO
CONSERVATIVE THERAPY, THE PREGNANCY MAY CONTINUED
UNDER CLOSED OBSERVATION.
• ADVENT OF HYPOXIA RETINOPATHY --- INDICATE TERMINATION OF
PREGNANCY