(1) A space diagonal is a line that connects opposite vertices through the center of a rectangular prism.
(2) The Pythagorean theorem can be used to calculate the length of a space diagonal by treating it as the hypotenuse of a right triangle formed by the dimensions of the prism.
(3) For example, in a prism measuring 28cm by 12cm by 16cm, the space diagonal AG is calculated to be 34.4cm using the Pythagorean theorem and considering triangles ABC and ACG.