This document provides an overview of psychotherapeutic medication. It begins by defining mental illness and providing demographic statistics. It then discusses the history of treatment, including early abusive practices and the development of electroconvulsive therapy. The document outlines several mental disorders like anxiety, mood disorders, and psychosis. It provides details on diagnosis and specific medications used to treat various disorders. The document notes challenges like dual diagnosis, non-compliance, and the increased societal impacts of widespread medication use.
Presentation by Dr. Jacob Kagan on addiction psychiatry, covers the neurobiology of addiction, diagnosis and management od dually-diagnosed patients, relapse prevention, psycopharmacology interventions and more. http://www.jacobkaganmd.com
Presentation by Dr. Jacob Kagan on addiction psychiatry, covers the neurobiology of addiction, diagnosis and management od dually-diagnosed patients, relapse prevention, psycopharmacology interventions and more. http://www.jacobkaganmd.com
Depression
Background
Pathophysiology
• The monoamine theory of depression is that it results from a central deficit in the monoamine neurotransmitters serotonin (5-HT) and norepinephrine.
• Other reported physiological features include ↑cortisol and a blunted TSH response.
• However, there is no widely accepted and definitively proven biological model of depression.
Epidemiology
• Time course: for most it is an episodic illness, but for other it follows a more chronic course.
• Incidence: 5% annual risk, 20% lifetime risk.
Presentation
DSM and NICE criteria
These are based on DSM-4, though DSM-5 does not significantly differ.
Major depressive disorder is ≥2 weeks of low mood and/or anhedonia, and at least 4 symptoms out of:
• ↓Energy or fatigue.
• ↓Concentration
• ↓Weight/appetite.
• Disturbed sleep, which commonly includes early waking. Diurnal pattern to symptoms also seen, with symptoms often worse in the morning.
• Slowing of thought and movements (psychomotor slowing) or agitation.
• Ideas of worthlessness or guilt.
• Recurrent thoughts of death or suicide.
• All but the last 2 are considered 'biological' symptoms.
There are various treatment methods for bipolar disorder, including; drug therapy, psychotherapy, mental health supplements and ect. http://mentalhealthlivingwithbipolar.blogspot.com/p/blog-page_27.html
a disease in which patient sometimes feels mania and sometimes depressed ...it is a psychiatric illness.....symptoms last for 3-6 months...but it is curable with antidepressants and antipsychotics....
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A Strategic Approach: GenAI in EducationPeter Windle
Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
This Gasta posits a strategic approach to integrating AI into HEIs to prepare staff, students and the curriculum for an evolving world and workplace. We will highlight the advantages of working with these technologies beyond the realm of teaching, learning and assessment by considering prompt engineering skills, industry impact, curriculum changes, and the need for staff upskilling. In contrast, not engaging strategically with Generative AI poses risks, including falling behind peers, missed opportunities and failing to ensure our graduates remain employable. The rapid evolution of AI technologies necessitates a proactive and strategic approach if we are to remain relevant.
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Embracing GenAI - A Strategic ImperativePeter Windle
Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
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2. What percentage of
people with a
mental illness seek
professional help?
A. 90%
B. 55%
C. 40%
D. 10%
90%
55%
40%
10%
0%
25%
71%
4%
3. Mental Illness
The National Alliance
on Mental Illness
defines mental
illnesses as: “medical
conditions that disrupt
a person’s thinking,
feeling, mood, ability
to relate to others and
daily functioning”
4. Demographics
10-15% of the general population receive
drugs for emotional problems each year
43% of people with mental disorders reside
in the US and Europe
1 in 3 Americans suffer from a mental
disorder
Antidepressants are the medication most
frequently used by people aged 18–44
5. Early Treatment of Mental
Disorders
Before 1950, people
with mental illness
were subjected to
abysmal treatment
Depression was
treated with
amphetamines; other
types of mental
illnesses were
treated with
sedatives
6. History
Electroconvulsive therapy (ECT), first developed in
1938, was used to treat depression and psychosis
Electrical activity in the brain is temporarily
interrupted and a seizure within the brain is triggered
Many patients experienced adverse cognitive effects
Despite concerns, ECT is still a treatment option
8. Diagnosis of Mental Disorders
DSM-5 criteria
Clinically significant distress or impairment in social,
academic (occupational) or other important areas of
functioning
Not attributable to the physiological effects of a
substance or another medical condition
Dual-diagnosis
VERY QUICK OVERVIEW – YOU WILL NOT BE ABLE
TO DIAGNOSE ANYONE, EVEN YOURSELF!
9. It is important to rule out substance use
as a cause of symptoms because
A. Patients could be lying
about their use of
drugs
B. Intoxication can
resemble some
symptoms of mental
disorders
C. A patient can’t be
diagnosed with both
mental illness and
substance abuse
Patientscould
belying
...
Intoxication
can
resem
bl...
A
patientcan’tbe
diag...
0%
8%
92%
10. How are you keeping up?
A. Great, this makes
sense.
B. Pretty well, but I’m
going to need to
do some reading.
C. Michelle, I’m lost.
Great,thism
akessense.
Pretty
w
ell,butI’m
going...
M
ichelle,I’m
lost.
71%
0%
29%
11. Disorders with Anxiety
Symptoms
Anxiety Disorders
Panic Disorder
Social Anxiety
Phobias
Obsessive
Compulsive Disorder
Post-traumatic Stress
Disorder
Treatment often
includes
use of sedative-
hypnotic
drugs
19. Depression
Depressed mood most of the day, nearly every day
Diminished interest or pleasure in activities
Disturbances in appetite
Disturbances in sleep
Psychomotor agitation or retardation
Fatigue/loss of energy
Feelings of worthlessness/
guilt
Diminished ability to
concentrate
Recurrent thoughts of
death
21. Before giving antidepressants to
children:
A. The medications were
tested for effectiveness
B. The medications were
tested for safety
C. The medications were
not tested on children
Them
edicationsw
erete...
Them
edicationsw
erete...
Them
edicationsw
ereno...
0%
73%
27%
24. Anti-depressant
Medications
Monoamine oxidase inhibitors (MAOIs)
Tricyclic antidepressants
Selective serotonin reuptake inhibitors
(SSRIs)
Serotonin and norepinephrine reuptake
inhibitors (SNRIs)
Atypical antidepressants that do not fall
into one of the above categories
25. SSRIs
Selective serotonin reuptake
inhibitors (SSRIs)
Antidepressant medications that increase the
concentration of serotonin in the brain
Reduce aggressive and violent behavior
Adverse effects include sexual dysfunction,
increase in weight, and altered sleep patterns
Not much more effective than placebos
26. Although antidepressants
are only slightly more
effective than placebos,
most patients feel they help.
A. True
B. False
True
False
0%0%
27. Manic Episode
Inflated self-esteem
Decreased need for sleep
Talkative
Flight of ideas
Distractibility
Increase in goal-directed activity
Excessive involvement in risky behavior
29. A manic episode can resemble:
A. Being drunk
B. Being high on
marijuana
C. Being high on
cocaine
BeingdrunkBeinghigh
on
m
arijuanaBeinghigh
on
cocaine
4%
96%
0%
30. Medications for Bipolar
Disorder/Manic Episode
Lithium
Effective for acute mania and prevents
recurrence
Maximal benefit is achieved in one to two weeks
Effective for unipolar depression not responsive
to other antidepressant drugs
The therapeutic window is small – three to four
times the therapeutic level can cause grave
consequences
Chlorpromazine
Fewer toxic side effects
31. Non-compliance with med
schedules is a problem with lithium
because
A. Patients are
hallucinating
B. Patients like the feeling
of a manic episode
C. It takes several months
for the dose to reach
therapeutic threshold
Patientsarehallucinating
Patientslikethe
feeling..
Ittakesseveralm
onthsf..
0%
15%
85%
32. Psychosis
Psychosis
Severe mental condition marked by loss of contact with
reality
Organic psychoses
Have physical causes such as excessive drug use, brain
infections, metabolic or endocrine disorders, brain tumors,
and neurological diseases
Functional psychoses
Have no known or apparent cause (e.g. schizophrenia)
34. The number of children taking
antipsychotic drugs has increased
in the US. In Europe:
A. Rates have slightly
increased as well
B. Rates have remained
the same
C. Rates have decreased
D. Rates have increased
at an alarming rate,
doubling the numbers
Rateshaveslightlyincre...
Rateshaverem
ained
the...
Rateshavedecreased
Rateshaveincreased
ata...
23% 23%
31%
23%
35. Psychosis is
A. Blunting of
emotional
expression
B. A loss of touch
with reality
C. Always marked by
hallucinations
Bluntingofem
otionalex...
A
lossoftouch
w
ith
reality
Alw
aysm
arked
byhalluc...
0%
15%
85%
37. Antipsychotic Drugs
Antipsychotic drugs (neuroleptics) used
particularly for schizophrenia
Pharmacologically different from other
sedative-hypnotic drugs
They block dopamine
Four to six weeks for maximum
effectiveness
38. Antipsychotic Drugs
Absorbed erratically
Sometimes given by injection so the drug
can be released slowly into the
bloodstream
Build up in fatty areas of brain and lungs,
and cross the placenta to affect the fetus
39. Antipsychotic Drugs
Patients almost always show improvement,
but a small percentage gets worse
Improvement is most rapid during the first
several weeks of treatment
Although many people taking antipsychotic
drugs relapse, it appears that these drugs
reduce violent behavior
40. Side Effects
Parkinsonism
tremor, slow movement, impaired speech or
muscle stiffness — especially resulting from the
loss of dopamine
Tardive dyskinesia
Motor disorders such as involuntary repetitive
facial movements, lip smacking, involuntary
movement of trunk and limbs, and twitching
41. Which is not true of
antipsychotic drugs?
A. Takes 4-6 weeks for max
effect
B. Side-effects are mild and
easily reversed
C. They are absorbed
unevenly
D. They block dopamine
Takes4-6w
eeksform
ax...
Side-effectsare
m
ild
and...
Theyare
absorbed
unevenly
Theyblockdopam
ine
8%
4%
19%
69%
42. Dual Diagnosis
• Two or more
co-existing
mental
illnesses
• Common
Example:
• Substance
Use Disorder
& Depression
43. Increased Medication Use =
Consequences for Society
Number of hospitalizations decreased
Lack of outpatient services
Psychiatrists spend much time
prescribing/managing medications
Civil Rights issues around hospitalization
Non-compliance with medication regimen
Jail
Homelessness