The document discusses various substances that are commonly abused and their effects. It covers alcohol, hallucinogens like LSD and mushrooms, stimulants like cocaine and meth, marijuana, opiates like heroin, inhalants, MDMA (ecstasy), Rohypol (flunitrazepam), ketamine, and GHB. For each substance, it summarizes the intoxication effects, risks of long-term abuse like organ damage and addiction, and withdrawal symptoms. Nursing considerations are also discussed for assessing and treating patients with substance abuse and addiction issues.