This document discusses sinuses, fistulas, and cysts. It defines a sinus as a blind ending tract lined by granulation tissue leading into tissues, while a fistula is an abnormal communication between two epithelium lined surfaces. Sinuses and fistulas can be congenital or acquired. Common causes of persistence include the presence of foreign bodies, necrotic tissue, epithelialization/endothelization of the tract, malignancy, and specific conditions like diabetes or tuberculosis. Clinical examination involves inspection of the site, discharge, surrounding skin as well as palpation of temperature, tenderness, induration and lymph nodes. Investigations may include blood tests, discharge cultures and smears, imaging like X-rays or MRI