This PPT is mainly for the III yr MBBS - Students for whom this topic is important. Moreover mainly day today clinical practice practising doctors will come across these types of cases.
compartment syndrome, causes, compartments of legs,compartments of forearm,compartments of hand,compartments of foot, compartments of arm,compartments of thigh,fasciotomy of leg,fasciotomy of forearm, fasciotomy of hand,fasciotomy of foot, fasciotomy of thigh, fasciotomy of arm
compartment syndrome, causes, compartments of legs,compartments of forearm,compartments of hand,compartments of foot, compartments of arm,compartments of thigh,fasciotomy of leg,fasciotomy of forearm, fasciotomy of hand,fasciotomy of foot, fasciotomy of thigh, fasciotomy of arm
Shock is the state of not enough blood flow to the tissues of the body as a result of problems with the circulatory system.Initial symptoms may include weakness, fast heart rate, fast breathing, sweating, anxiety, and increased thirst. This may be followed by confusion, unconsciousness, or cardiac arrest as complications worsen.
Shock is divided into four main types based on the underlying cause: low volume, cardiogenic, obstructive, and distributive shock. Low volume shock may be from bleeding, diarrhea, vomiting, or pancreatitis. Cardiogenic shock may be due to a heart attack or cardiac contusion. Obstructive shock may be due to cardiac tamponade or a tension pneumothorax. Distributed shock may be due to sepsis, spinal cord injury, or certain overdoses.
The diagnosis is generally based on a combination of symptoms, physical examination, and laboratory tests. A decreased pulse pressure (systolic blood pressure minus diastolic blood pressure) or a fast heart rate raises concerns. The heart rate divided by systolic blood pressure, known as the shock index (SI), of greater than 0.8 supports the diagnosis more than low blood pressure or a fast heart rate in isolation.
Treatment of shock is based on the likely underlying cause.[2] An open airway and sufficient breathing should be established.[2] Any ongoing bleeding should be stopped, which may require surgery or embolization.[2] Intravenous fluid, such as Ringer's lactate or packed red blood cells, is often given.[2] Efforts to maintain a normal body temperature are also important.[2] Vasopressors may be useful in certain cases.[2] Shock is both common and has a high risk of death.[3] In the United States about 1.2 million people present to the emergency room each year with shock and their risk of death is between 20 and 50%
Shock is the state of not enough blood flow to the tissues of the body as a result of problems with the circulatory system.Initial symptoms may include weakness, fast heart rate, fast breathing, sweating, anxiety, and increased thirst. This may be followed by confusion, unconsciousness, or cardiac arrest as complications worsen.
Shock is divided into four main types based on the underlying cause: low volume, cardiogenic, obstructive, and distributive shock. Low volume shock may be from bleeding, diarrhea, vomiting, or pancreatitis. Cardiogenic shock may be due to a heart attack or cardiac contusion. Obstructive shock may be due to cardiac tamponade or a tension pneumothorax. Distributed shock may be due to sepsis, spinal cord injury, or certain overdoses.
The diagnosis is generally based on a combination of symptoms, physical examination, and laboratory tests. A decreased pulse pressure (systolic blood pressure minus diastolic blood pressure) or a fast heart rate raises concerns. The heart rate divided by systolic blood pressure, known as the shock index (SI), of greater than 0.8 supports the diagnosis more than low blood pressure or a fast heart rate in isolation.
Treatment of shock is based on the likely underlying cause.[2] An open airway and sufficient breathing should be established.[2] Any ongoing bleeding should be stopped, which may require surgery or embolization.[2] Intravenous fluid, such as Ringer's lactate or packed red blood cells, is often given.[2] Efforts to maintain a normal body temperature are also important.[2] Vasopressors may be useful in certain cases.[2] Shock is both common and has a high risk of death.[3] In the United States about 1.2 million people present to the emergency room each year with shock and their risk of death is between 20 and 50%
Flexor tendons - enclosed by synovial sheaths.
Tendons - blood supply through synovial folds known as vincula, each
tendon having two, vincula longa and vincula brevia.
The sheath of the little finger is continuous with the ulnar bursa covering
the flexor tendons in the palm.
The flexor pollicis longus is covered by a single sheath throughout, the
radial bursa.
Synovial sheaths can be infected producing tenosynovitis. Infection can
spread throughout the sheath. Infection of the sheath of the little finger can thus spread up the distal aspect of the forearm into the space of Parona.
This slide gives you information regarding the Types of Palmar spaces, their contents & boundaries. Also certain aspects of Applied anatomy has been enlightened in the interest of Integrated teaching.
Fascial spaces are potential spaces that exist between the fasciae and underlying organs and other tissues.infection of orofacial & neck region, particularly those of odontogenic origin,have been one of the most common diseases in human being.
Dr. Ahmed M. Adawy, Professor Emeritus, Dep. Oral & Maxillofacial Surgery. Former Dean, Faculty of Dental Medicine
Al-Azhar University. The Pathogenesis of infection in oro-facial region due to odontogenic origin is a common clinical issue. bacterial invasion to deeper tissues usually a spread from diseased dental pulp. Recent evidences indicated a multi-microbial nature. The spread of infection is governed by the thickness of the investing bone and the anatomical relation of the tooth root to the attached muscle. Infection could spread from one facial space to another, and the condition may be aggravated to life threatening situations.
Space infection. by Dr. Amit T. Suryawanshi, Oral Surgeon, Pune All Good Things
Hi. This is Dr. Amit T. Suryawanshi. Oral & Maxillofacial surgeon from Pune, India. I am here on slideshare.com to share some of my own presentations presented at various levels in the field of OMFS. Hope this would somehow be helpful to you making your presentations. All the best.
Space infection. by Dr. Amit Suryawanshi .Oral & Maxillofacial Surgeon, Pun...All Good Things
Hi. This is Dr. Amit T. Suryawanshi. Oral & Maxillofacial surgeon from Pune, India. I am here on slideshare.com to share some of my own presentations presented at various levels in the field of OMFS. Hope this would somehow be helpful to you making your presentations. All the best & your replies are welcomed!
his topic - Intestinal Obstruction is very important for final year MBBS - Students & the Medical Officers, as it is one of the commonest causes of Acute Aabdomen. The PPT - contains the classification, common causes, clinical features & management aspects of Intestinal Obstruction. Also, highlights the differentiating features of Plain X-ray abdomen of Small & Large Bowel Obstruction.
This topic is very important for an MBBS Students as it is one of the common cases a Medical Officer will come across during their Surgical Postings. Moreover it is always a Debate in treating the patient either an Physician or a Surgeon...Always it is one of the Devastating conditions of abdomen...
This topic comes under the category - Venous Diseases. It is very important for a 3rd year MBBS Student to know about Varicose Veins, which is one of the commonest diseases encountered among out-patients.
This topic is under the Chapter - Arterial Disorders. The MBBS Students should know the types of Aneurysms and particularly Abdominal Aortic Aneurysms.
This topic covers the etiology, types, pathogenesis and management of Hypovolemic & Septic Shock. It is very important for MBBS Students both theoritical and clinical aspect. Also they should know the hemodynamics of the above both types of Shock.....
This topic is under the Arterial Diseases of the Limbs. The MBBS students should know the Classification and Pathogenesis of Diabetic Foot. Also the different types of Gangrene and difference between Dry & Wet Gangrene....
This topic is under the category of Arterial Diseases. One of the subtopic is CLI. One of the ommon causes for CLI, is Atherosclerosis, which is discussed in this PPT.
This topic is under the category of Arterial Diseases. It is very important for an MBBS students to know about ALI, so as to treat them initially and then refer them to vascuar surgeons.
This topic is under the General Principles of Surgery. It is very important for MBBS - Students. New method of resuscitation called the Damaged Control Resuscitation is carried out in controlling the hemorrhage.
This topic covers the etiology, types, pathogenesis and management of Shock. It is very important for MBBS Students both theoretical & clinical aspect. Also they should know the hemodynamics across the types of shock in treating the patients....
This topic is under the General Principles of Surgery for MBBS Students. It also deals with Scars & Contractures. The student should know to differentiate between Hypertrophic Scar & Keloid..
This topic is mainly for MBBS Studnts. It is under the General Principles of Surgery. Students shoud know the phases of wound healing so as to treat them appropriately and select the correct method of dressing material....
This topic comes under the General Principles of Surgery for MBBS Students. The student should know the various types of wounds, their assessment and dressing methods.
IBD is very important topic even though the disease is prevalent in western countries. This PPT covers both the diseases side by side for comparing at same time and having an idea about them all together.
This topic is very important in day - today practice. Mainly this topic can be kept in clinical cases as well as OSCE's. for Final MBBS - Students. This PPT covers most of them in detail as far as possible.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
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- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
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New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
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New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
3. Introduction
• Hand is a compact actively functioning unit due to its
mechanical & sensory functions.
• It is one of the most developed structures in the human
evolution.
• Infection may be due to minor injuries or blood borne.
4. Spaces of the hand
• Radial bursa
• Ulnar bursa
• Mid palm.space - space of Parona
• Thenar space
• Dorsal subcutaneous space
• Sup. pulp spaces of finger
Radial
bursa
Space of Parona
Mid palmar
space
Ulnar bursa
Thenar space
5. Tendon Zones – Modified Verdan Zone
• Zone 1 - One tendon only (FDP)
from middle of middle phalanx
distally
• Zone 2 - Two tendons (FDS &
FDP) from MCP joints to middle of
middle phalanx
• Zone 3 - Central palm
• Zone 4 - Tendons in the carpal
tunnel
• Zone 5 - Tendons proximal to the
carpal tunnel
8. General Features
• Infection spreads faster in all
areas.
• Causes oedema over the dorsum of
hand. It looks like frog hand.
• Restricted movements of fingers
and hand. Hook, pinch, grip, grasp
are lost.
• Severe pain and tenderness, with
fever.
• Tender palpable axillary lymph
nodes are often present.
9. Classification
[I] Cut.& sub-cut.infections:
• Paronychia
• Pulp Space Infection (Felon)
• Web Space Abscess
[II] Fascial spaces infection :
• Deep Space Infection i.e.
midpalmar space, thenar space
& Parona’s space.
• [III] Inf. of the tendon with
its synovial sheath -
“tenosynovitis”.
• [IV] Inf. of the bone & joint -
“septic arthritis”.
• [V] Miscellaneous infections.
10. Investigations
• Pus for culture & sensitivity.
• Blood sugar.
• Urine sugar & ketone bodies.
• X-ray of the part.
11. General Principles
• Position of rest & function
• Elevation of hand - ↓oedema
• Early recognition – I & D
• Blood less field
• After trt – Physiotherapy
12. Complications
• Stiffness of digits and hand (ankylosis)
• Deformity and disability
• Bacteraemia and septicaemia
• Osteomyelitis of bones
• Suppurative arthritis of joints
• Paralysis of median nerve
13. 1. Paronychia
• Most common hand infection.
• Infection of the soft tissues
surrounding the fingernail.
• Minor injury - is the common
cause.
• Severe throbbing pain and
tenderness with visible pus under
the nail root.
• The pus is drained by making an
incision over the Eponychium.
14. 2. Felon
• A felon is an abscess of the distal
pulp of the thumb or finger.
• Usually a minor injury – finger
prick.
• Infection results in edema and
increased pressure within the
closed compartment.
• Drainage of terminal pulp space
by an longitudinal deep incision.
15. 3.Web space Abscess
• There are 4 triangular web spaces
filled with fat between the dorsal
and volar skin.
• Begins beneath palmar callus – in
laborers.
• Oedema of dorsum of hand + Max.
tenderness is on the volar aspect.
• ‘V’ sign—Separation of fingers.
• Incisions – 1 dorsal and 1 palmar.
• Web - not incised
16. 4.Deep space Infection
• These are infections in the
potential deep spaces of the
hand, i.e. Midpalmar space,
Thenar space & Parona’s space.
• Protects neuro-vascular structures
& permits gliding of tendons
within the hand.
• Infections - may follow blood
spread, penetrating injury or
rupture of pus from a flexor
tendon sheath.
17. 4-a.Thenar space Infection
• It lies post. to the long flexor
tendons to the index finger and in
front of the adductor pollicis
muscle.
• Pain and swelling of thenar
eminence and first web space.
• Thumb is held abducted & flexed.
• Combined dorsal and volar
incisions. Avoid injury to branches
of median nerve.
18. 4-b.Mid-palmar space Infection
• It lies post. to the long flexor
tendons to the middle, ring and
little fingers. It lies in front of the
interossei and the 3rd,4th& 5th
metacarpal bone.
• Loss of normal hand concavity
with dorsal edema – “Frog’s
hand”. Pain with movement of
3rd and 4th digits.
• Either longitudinal or transverse
approach for drainage.
19. 4-c.Parona space Infection
• It is deep in the distal forearm
between the PQ muscle & the FDP
tendons.
• This space is contiguous with the
radial bursa, ulnar bursa and
midpalmar space.
• A flexor tendon sheath infection may
extend proximally to involve the
bursae and Parona’s space.
• Swelling, tenderness, & occasionally
fluctuance of the distal volar
forearm. Digital flexion may be
painful.
20. 5.Dorsal space Infections
• Diffuse swelling – Dorsum of hand
• Edema will be seen
• Normal concavity - palm
• Digital extension – very painful
• Treatment is similar to that recomm.
for other infections
21. 6.Tenosynovitis
• It is the bacterial inf. of flexor tendon sheaths.
• It is the inflam. the fluid-filled sheath (called
the synovium) that surrounds a tendon.
• Common flexor synovial sheath (ulnar bursa)
[FDP / FDS]
• The synovial sheath of the tendon of flexor
pollicis longus (radial bursa).
• Both comm. with each other in 80% of cases.
22. Tenosynovitis - contd
“Kanavel Sign” –
• Finger in slight flexion
• Fusiform swelling
• Severe pain on extension.
• Tenderness - tendon sheath
• Treatment is similar to that recomm. for
tendon infections: open or closed irrigation,
leaving a drain in situ and antibiotic cover.
24. Callosity
• It is a hard, thickened skin
occurs as a protective
measure seen in wider area
usually over heel & heads of
metatarsals.
• A callosity protrudes
outwards from the skin.
25. Corn
• It is localized area of
thickening over a bony
projections like heads of
metatarsals.
• It presses over the adjacent
nerves causing pain.
• It can get infected causing
severe pain and tenderness
with inability to walk.
26. Ingrow Toe nail ( Onychocrytosis )
• It is due to curling of the side
of nail inwards, resulting in
repeated irritation &
infection of overhanging
tissues in the nail fold.
• It is common in great toe and
is often bilateral.
• Zadik’s or Fowler’s operation
27. Athlete’s Foot
• It is the fungal infection of the skin
between the toes - Tinea pedis.
• Fungi enter through cracks; survive due
to moisture in between toes.
• Skin is swollen, red, with sticky fluid &
blisters. Itching, deep cracks, pain &
discharge are common
• Part should be kept dry. Cotton, clean
socks should be worn.
• Oral antifungals, antihistaminics and
topical antifungals are used.
28. Key Points to Remember
Do’s Don’ts
Examine hand carefully Do not incise every infected digit
Think of other diagnosis Do not make puncture incisions
Wait for abscess to localize Do not injure digital vessels or nerves
Place adequate depth and length of incisions Do not place incisions crossing the creases
Immobilize, elevate the hand Do not close bite wounds
Antibiotics & proper dressings Do not forget pus culture and sensitivity