Sickle cell anemia is a genetic blood disorder caused by abnormal hemoglobin in red blood cells. It occurs when someone inherits two copies of the sickle cell gene, one from each parent. Sickle cells are stiff and sticky, causing blockages in blood vessels and oxygen loss to organs. Doctors diagnose it through a blood test showing sickle hemoglobin cells. While there is no cure, treatments aim to relieve symptoms and complications through medications, transfusions, and stem cell transplants. Managing sickle cell involves a healthy lifestyle to prevent crises and infections.