This document discusses a study on the effects of soil-structure interaction (SSI) on the seismic response of framed structures. Three-story, seven-story, and fifteen-story reinforced concrete frames are modeled in STAAD-PRO software placed on three types of soils: hard, medium, and soft. The structures are analyzed both with and without considering SSI to understand how SSI affects structural properties like natural time period, base shear, and seismic response. The analysis shows that considering SSI leads to increased time periods, displacements, accelerations, and base shear compared to fixed-base analysis that does not account for soil flexibility. SSI has a more significant impact for taller buildings and those on soft soils.