Science- Medicine - Evidence WHAT FOR ???

1. Science – Medicine – Evidence
Dr. Remya Krishnan MD PhD

2. Man & Medicine
• Medicine cannot be studied without studying man
• The purpose of inventing Medicine is to heal man and not to get
mere approval for medicine .
• Without healing man, there is no use for a medicine
• Emerging benefits along with risks are not healing
• Healing disease produces health , so health is the only evidence of
healing and criterion for approval of anything as medicine

3. Science
• Science is systematically organised knowledge and shasthra refers to
knowledge in a defined area of practice , so both are same.
• Ayurveda is a shasthra / science which cover general truths of
operation of theorems, laws and principles both general and specific
tested and verified by multiple scientists in multiple ways and
established by cause- effect relationship.
• Ayurveda unlike modern science is a deterministic form of knowledge
like Mathematics which could be proven by astute knowledgeled
application of the same unlike the statistical significance and
probability

4. Science vis-a vis Statistics
• Science describes how much certainity is there in results of
application, why and how while statistics describe how much
uncertainity is there in the results without why and how.
• Understanding of any natural phenomenon cannot have p value ,
rather it is the product of science led thinking and trying to
understand the phenomenon in its unique live setting.
• Theorems are real science while theqries are not . There is not even a
single theory in Ayurveda, all are theorems.

5. Scientific truth
• Applied Science – Principles (Tatwas) of true science applied in
different situations.
• Scientific truths are true for me and you, for everyone and hence the
are best objective uniform standards to verify observations.
• Scientific truths of today will not turn out to be tomorrow’s folly.
• Scientific truths provide explanations and understanding of cause
mechanism effect relationship of every natural phenomenon

6. Scientific Method in Ayurveda
• Ask a question approved by science
• Background research in science
• Deriving assumptions based on back ground research in science
• Testing of educated assumptions
• Logical reasoning of results of testing by logics in science (
Shasthrasahita tarka)
• Make a conclusion which is confirmatory and evidence based (
Evidence base refers to transparency of innate logic established and
replicality of the same)

7. Pre clinical research of Ayurveda
• Transformation of basic research evidence into potential leads for
Applied research in a realistic clinical setting.
• The most interesting part of research for Pratipatthi jnana
• We, the SBEBA pioneers have initiated pre clinical research right from
2003 .
• The cause – mechanism- effect relationship is verified in this stage of
research .
• As the research is to explore the relation between cause and effect of
the clinical condition and not the action of medicine , the intended
effect is only counted valid and not benefits and risks

8. SBEBA- Science Based Evidence Based Ayurveda
• Modern science prefers to isolate and understand one thing at one time but
man is a highly complex and dynamic machinery where multiple intertangled
cause mechanisms pave for the same or different effects and hence Yuktijnana
in Ayurveda is exploring multiple causes for the single effect manifested in
single or multiple systems for dealing with multiple pathogeneses with a
single common principle oriented approach (Food, regimen, medicated water)
with predicable outcome in the same subject.
• Yukti is led by shasthraartha karmaanusheelana and yukti developed by that
process is not mere assertion, but rather the truth.
• Yukti leads to the discovery of Pratipatti jnana and SBEBA incorporates
Pratipatti jnana developed by the foresaid technique
Disease HealthMultiple causes
Perceiving Foreseeing
Treatment PrincipleDiagnosing

9. Why SBEBA
• SBEBA has the components of precision, transparency and
replicability
• “ Karya tatwa visheshajna: Prathipatthaou na muhyathi
Amoodhah phalamapnothi yadamohanimittajam”
• SBEBA is meant to make a physician Karya tatwa “visheshajnah”
• SBEBA enables to practice Shasthraarthakarmaanusheelana , the
intended way of scientific Evidence Based Practice in Ayurveda.
• SBEBA abandons probability instead of inducing the same.

10. To become an SBEBA practitioner
• Constant Learning of SBEBA tatwas- Comprehension- Practice
• Leaving medicine/ treatment oriented thinking
• Probing into the specific and specialised cause mechanisms working
in the patient by applying SBEBA tools and explore them.
• Understanding that benefits are not the intended results
• Systematic documentation of appraisal and calculations performed in
every patient and modifications if any along with Upayas and Arthas

11. WHY SBEBA
• Intended patient outomes with most minimum dosage of most minimum
medication in intended time
• Revolutionary transformative approach for intended updation for Ayurveda
as well as Ayurveda physician.
• Knowledge gained from SBEBA can mean changing erroneous policies
adopted as standard for decades and thus result in scientific reformation of
clinical practice and research.
• Science of Ayurveda directly taking care of every patient instead of doctor’s
personal choice/ Pharmaceuticals ensures his protection
• “Evidence-based medicine in Ayurveda is the conscientious, explicit, and
judicious use of right Science Based Evidence in making decisions about
the care of individual patients.”

12. Evidence Triad Approach
• SBEBA has first and foremost devised and published a systematic
Evidence Appraisal Methodology of the patient by ETA
• ETA comprises of silver evidence of Hetu, golden evidence of Hetu-
Vyadhi and diamond evidence of pancha samprapthies in clinical
decision making
• ETA approach helps to integrate different diseases in the same subject
at the same time and guides to reverse them in the same time by
most minimum medicine/ intervention

13. Patient- Not a specimen
• Evidence Based practice of Ayurveda by SBEBA improves
responsibility and consciousness of patient in his recovery process by
creating scientific awareness of his condition.
• The patient satisfaction improves with improvement of his health
condition hour by hour , day by day enabling the patient to build up
trust and value to this medical system.
• This naturally facilitates the journey of Ayurveda to Mainstream
Medicine of the country and the world

14. The five ways where SBEBA leads the conventional practice
• Helps physician to stay on the practice of Science Based Medicine
instead of Medicine Based Science.
• The physician employs intended shasthraarthas in clinical decision
making instead of anecdotes or self or shared experiences of others.
• Improves the transparency, accountability and values ( best quality
intended care at lowest expense)
• The choice and priority of every patient becomes Ayurveda
• Enhances the professionalism and confidence of Ayurveda physicians
of all IQ levels to take care of self and others

15. Responsibilities of SBEBA practioner
• Learn- Ponder- Practice- Propagate the crucial necessity of emerging SBEBA to
introduce precision and quality of system and physician.
• Dismissal of science by any means should be individually and collectively opposed
and condemned openly because rejecting science is bad for the patients and
worst for our science and we are responsible for both.
• There is no need of knowing everything in science to oppose nonsense in basic
level . A first standard boy without knowing advanced mathematics can
confidently oppose mistakes in counting from1-10
• High time pseudolegends are to be exposed to the world and this is possible only
by ASK- ARGUE method and never by “ Yes your honour method”
• Future Ayurveda is determined by us , so do not consider SBEBA selfishly for
personal needs alone , it is a mission to revive the quality and purity of Ayurveda

17. SBEBA – The present and future of Ayurveda