Ayurvedic research should aim to enhance clinical knowledge and benefit patients, not commercial interests. True research starts from thoroughly understanding classical texts to explore unknown aspects. It must apply Ayurveda's scientific principles to generate practical guidance for accurate diagnosis and treatment tailored to individual patients. Well-designed studies can help optimize Ayurvedic knowledge, but the focus should remain on improving healthcare, not interpreting Ayurveda through modern frameworks. Researchers must re-examine priorities and ensure an unbiased, patient-centered approach aligned with Ayurveda's goals of attaining health.
Manuscriptology - An Introduction
Under the guidence of Dr. SM Vaidya sir and Dr. Girish. Sir
This gives an easy understanding for the people who go for Ayurveda Manuscriptology.
Ayurveda a Food Science perfectly deals with the different kinds of food preparation which can be utilized in day to day life according to prakritti(basic constitution), desha(place), dosha(humors), kala(time).
Philosophical Background of Darshana ShastraUmapati Baragi
Ayurvedic Science is based on the fundamental sciences called ‘Darshana’. The word ‘drs’ that means to see, look, view or The mirror of knowledge or the source of knowledge. Seeing means – External things and Inner self (soul)
Darshana’ is concerned with the vision of ‘truth and reality’.
Manuscriptology - An Introduction
Under the guidence of Dr. SM Vaidya sir and Dr. Girish. Sir
This gives an easy understanding for the people who go for Ayurveda Manuscriptology.
Ayurveda a Food Science perfectly deals with the different kinds of food preparation which can be utilized in day to day life according to prakritti(basic constitution), desha(place), dosha(humors), kala(time).
Philosophical Background of Darshana ShastraUmapati Baragi
Ayurvedic Science is based on the fundamental sciences called ‘Darshana’. The word ‘drs’ that means to see, look, view or The mirror of knowledge or the source of knowledge. Seeing means – External things and Inner self (soul)
Darshana’ is concerned with the vision of ‘truth and reality’.
The concept of pathya apathya w.s.r. to charak samhitabrijeshbhu
Ayurveda has holistic and scientific approach in health management. It emphasizes much more on diet and regimen along with medicines. The diet and regimen which is beneficial to the body and gives the happiness to the mind is known as Pathya and opposite to that is known as Apathya. Most of the health problems develop due to the faulty eating habits and regimen. Ayurveda deals with the pathya vyavastha (planning of diet- dietetics) in a very scientific way. The planning of diet mentioned in our classical literature is very rational and based on certain principles. Lot of importance is given to the diet with regard to its processing, quality, quantity and so on.
Due consideration is given to the atmosphere, psychological condition, status of health, digestion etc. of the person while dealing with this issue. The diet should also be planned according to the age, season, habitat and the preference of the person.
Ayurveda strongly believes in using drugs with particular tastes in treating diseases. This presentation will help you understand the basics of rasa and its applied aspects in planning treatment protocol.
The concept of pathya apathya w.s.r. to charak samhitabrijeshbhu
Ayurveda has holistic and scientific approach in health management. It emphasizes much more on diet and regimen along with medicines. The diet and regimen which is beneficial to the body and gives the happiness to the mind is known as Pathya and opposite to that is known as Apathya. Most of the health problems develop due to the faulty eating habits and regimen. Ayurveda deals with the pathya vyavastha (planning of diet- dietetics) in a very scientific way. The planning of diet mentioned in our classical literature is very rational and based on certain principles. Lot of importance is given to the diet with regard to its processing, quality, quantity and so on.
Due consideration is given to the atmosphere, psychological condition, status of health, digestion etc. of the person while dealing with this issue. The diet should also be planned according to the age, season, habitat and the preference of the person.
Ayurveda strongly believes in using drugs with particular tastes in treating diseases. This presentation will help you understand the basics of rasa and its applied aspects in planning treatment protocol.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
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Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
1. Ayurveda Research- What matters and Why?
Dr. Remya Krishnan PhD (Ay)
Associate Professor & Head
Dept of Applied Pharmacology of Ayurveda,
RGAMC, Mahe
2. Re-search
• Research is a voyage discovery or a journey
from known to unknown.
• Hence “ the known” is the starting point of
research
• No research can “initiate from the
unknown”as “Re-search” means once again
looking thoroughly through existing
knowledge to explore deep .
3. Patient Oriented Research
• The objective of research in Ayurveda is to attain
Pratipatti jnana
• Pratipattijnana technically refers to highly specific and
specialised knowledge which guides the physician to
arrive at accurate diagnostic an therapeutic decisions
based on every unique clinical situation.
• Hence in Ayurveda , every research problem is
ultimately meant to be “of the patient- for the
patient” and not “of the medicine- for the medicine”
• Thus it is evident that Ayurveda emphasises upon
Patient Oriented Research only and not the Medicine
Oriented one
4. Research problem
• A research problem is a statement about an
area of concern, a condition to be improved,a
difficulty to be eliminated, an unclear issue
that exists in scholarly literature of Ayurveda
in theory or in practice that points to the need
for meaningful understanding and deliberate
exploration.(https://library.sacredheart.edu/c.
php?g=29803&p=185918)
5. Re-search in Ayurveda
• Is the research question relevant for clinicians or
patients ?
• Are the design and methods abide by the inbuilt
standards of science of Ayurveda ?
• Is the transparency and reproducibility of the
study ensured by the innate core diagnostic and
therapeutic principles of science of Ayurveda and
thus unbiased?
• Is the study and its outcome clinically meaningful
?
6. Objectives of Ayurvedic research
• To explore and optimise the scientific
knowledge of Ayurveda to meet specific and
specialised health care needs of society.
• To attain and improve the health of people
world wide .
• To expose the innate potential and scientificity
of Ayurveda as most deserving independent
medical system and not misinterpret as
Traditional/ Complementary Medicine
7. • The current research environment in Ayurveda is not
for thinking about such noble goals.
• Funders have adopted long drawn out bureaucratic
processes for their grant giving based on western
research methodologies and not the innate scientific
ones.
• Funders operate within political/ vested interests and
hardly care to make Ayurvedic research policies
unbiased to expose Ayurveda as it is.
• The economic benefits and commercial potential of
research is only considered today without any
involvement of science or ethics and Ayurvedic
research is currently counted as mere economic
engine for financial prosperity of individuals or
organisations
8. Rethink
• It is high time to stop and reflect on how we got
to this point and how we can restructure and
reframe Ayurvedic research for the benefit of
science and humanity.
• It is high time to remind ourselves about the true
purpose of Ayurvedic research.
• We need to adopt the ways to decide what kind
of research is required in Ayurveda , why and
how and what impact it is likely to have in the
targeted beneficiaries?
9. Basic/ Pure research
• Research conducted to increase the base knowledge
and understanding of fundamental biological and
functional mechanisms of life processes and disease
in man.
• Basic research begins by deeply learning and
comprehending laws, theorems and principles of
basic science of humanbeing explained in Ayurvedic
science.
• Though it is fundamental, as it is completely
functional and applied knowledge , it can be directly
effectively applied for solving different biomedical
problems in humanbeings .
10. Examples for basic research
• Basic research in Ayurveda – Re-learning
shasthraarthas based on Yukti led
Prathyaksha and Yukti led Anumana
Examples of learning :
• What are the Atma roopas of Vata?
• What are Saama kapha lakshanas?
• What are Kaphaavritha Samaana lakshanas?
11. Basic research
Example of application- Prathyaksha & Anumana
Observing features of rooksha aruna twagaasyatha and confirming
Vata jwara in a jwara patient.
Bad odour and cloudy urine with chills in the patient– Confirming
Saama pittaja jwara
Hence unlike modern science , Basic research in Ayurveda is 100
percent applicatory enterprise.
Unlike modern science , it cannot be performed in animals or
computer models or tissue cultures because the science of
Ayurveda is thoroughly explained based on working of man and his
own unique intrinsic and extrinsic cause circumstances .
12. Applied research
• Research that is directed towards specific
objectives such as the development of a new
drug, therapy or procedure.
• It involves the application of existing knowledge,
much of which is obtained through basic
research, to a specific biomedical problem.
• Applied research is encouraged in Ayurveda to
attain Pratipattijnana – To discover the best
means to reverse a disease condition
13. Pratipattijnana
• Pratipattijnana is not inventing new
medicines/procedures .
• Pratipattijnana is acquired by the process of
scientifically optimising the knowledge of
shasthraarthas to diagnose or resolve a specific
/many biomedical problems in a human subject.
• As the knowledge of shasthraarthas explained in
Ayurveda pertains to solely the humanbeing and
his cause- circumstances, it is impossible to do
applied research in animals or isolated tissues .
14. Examples for Applied research
• Applied research is defined as effective translation and
implementation of shasthraarthas into the unique cause –
circumstances of every individual patient.
• Is Doosheevisha / Amavisha guideline of Ayurveda applicable in
Autoimmune disorders ?Why and How ?
• Is my particular DUB in my patient fit for Pachana - Anulomana or
Snehana ? Why and How ?
• Is my particular Hypertensive patient fit for Vataanulomana or
Pittaanulomana ? Why and How ?
Culturing brain in shasthraarthas and deriving right conclusions by
their proper appraisal is to be done by Applied research in
Ayurveda.
15. Clinical research
• Clinical research is Applied research done in
clinical setting.
• Clinical research in Ayurveda builds upon the
knowledge learned through applied and basic
research and is done to ensure the results of
Applied research by repeating the scientific logic
in identical conditions.
• Clinical research in Ayurveda does not require
new formulations and does not evaluate benefits
and risks
16. Clinical research
• Clinical research is based on deeply standardised logics
derived in Applied research and not new medicines or old
ones.
• The innate logics determines the diagnosis, medicine/
treatment .
• The objective of Ayurvedic clinical research is to confirm
and establish the standardised logical guidelines and
protocols to diagnose or reverse a disease condition or
both and not claiming efficacy of any formulation or
procedure based on benefits and risks.
• The only side effect intended for scientific mode of reversal
of any pathogenesis in Ayurveda is health.
17. The classical medicines of Ayurveda
• The classical medicines of Ayurveda are not generalised ,
vague or baseless.
• As they are documented under variable disease contexts with
specific guidelines and not in a generalised manner, it is sure
and certain that they are formulated and established by both
basic and applied research before their documentation.
• The samhithas (Brihathrayees) are not documented as blind
therapeutic formularies with “this medicine in that disease”
• There are complex algorithms and principles to choose and
confirm the right medicine / treatment for every situation in
Ayurveda
18. The Scientific medicine – parameters
• SCIENTIFICALLY CHOSEN -Approved by logics of
science of Ayurveda for particular situation in
particular subject in paticular time.
• SCIENTIFICALLY ADMINISTERED – Administered in
optimum dosage and optimum time of
administration of medicine
• SCIENTIFICALLY ASSIMILATED – Intended Assimilation
happens only in optimised internal environment
19. • The Basic- Applied – Clinical Research in
Ayurveda is to ensure the administration of
Scientific medicine to every patient .
• Scientific medicine is defined as scientifically
chosen, scientifically administered and
scientifically assimilated medicine
• The scientificity can be ensured only by the
core principles and practice of Science Based
Medicine of Ayurveda.
20. Scientific verses – True intentions
• The trusted body of knowledge in science of Ayurveda
explains logical cause – effect relationship and not
mere observation of association.
• Ayurveda incorporates scientific knowledge which
provides a sound scientific basis for learning to be a
physician .
• But currently those scientific verses in samhithas are
merely confined for rewarding those who combine
hard work of mugging up verses with a well trained
memory and do nothing to enhance the right
comprehension of implication of those verses that may
in long term or career long most valuable
21. Conventional versus Intended
Conventional research methodology is meant to develop new
drugs and market them.
A true medical research methodology should be a
scientifically planned enterprise that will help in practically
resolving a health problem of man rather than extending the
problem.
Conventional medical research focuses on temporary risk-
benefit analysis and data building of the same and hence
extend the problem and do nothing to resolve.
A true medical research on the other hand must focus on
discovering new facts based on existing knowledge of science
, to verify and test their authenticity, to identify and establish
their cause effect relationship by testability and predictability,
to develop new algorithms to understand and solve clinical
problems which stay unresolved.
22. Research must explore and establish embedded logics
• A disease has some generalised cause(s) but every patient
acquire it by different reasons of susceptibility based on his
own unique cause and circumstances which may vary from
subject to subject.
• The course of the disease and response of treatment are
based on multiple intertangled intrinsic and extrinsic
components of his body as well as extrinsic factors which
he interacts with.
• Hence the research methodology applied should be able to
effectively intervene upon the working of these subtlemost
components and their scientific appraisal to emerge valid
conclusions
23. Science
• Science is not that which constantly changes ,
rather science is that which explains the changes .
• Hence conclusive evidences of cause mechanisms
attained by repeated experimentation of logics in
science in variable circumstances are theorems
and not the temporary valid theories / hypothesis
• Ayurveda incorporate theorems and no theories
24. Scientific theorems
• Scientific theorems are hence transparent and
predictive .
• They allow us to predict the unknown
phenomena and thus to focus research on more
narrowly defined areas.
• As the same cause mechanisms are observed to
yield same predictions (effects in
perception)yesterday and today, they are
regarded as science and not mere observations
25. No scientist in Ayurveda
• A scientist is originally bound by a set of values and
standards that embody honesty, integrity, objectivity,
and collegiality.
• These values are to be based on the innate principles
and practices characteristic of specific scientific
discipline.
• If there is no right education and comprehension of
background science and its intentions, there is no
integrity, objectivity of collegialilty in research and
therefore no scientist also.
• As no science is applied, there is no scientist in
Ayurveda today.
26. Current serious flaws in Ayurvedic reesarch
• Errors in comprehension of attitude and
approach of science
• Errors in comprehension of scientific verses and
their true intentions resulting in variable opinions
on same topic.
• Blind mimicking of modern research
methodology, its attitude and objectives in
Ayurveda.
• The scientific method of Ayurveda and not
modern medicine is to be applied in Ayurvedic
research
27. Physicians should update their science led intelligence
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sTvp/¡itvysamvS4aNtrai` yaNynuicNTymanainivmlivpulbu²erip
buRi²makulIkuyRu: ik. punrLpbu²e:||
Hence Shaasthraartha-karmaanusheelana is advocated
for physician scientists for prajnaa-shodhana and
samskarana.
28. TAKE HOME MESSAGE
– yStu rogmiv)ay kmaR~yarwte iw8k|
APyO82iv2an)StSy isi²yRd<C7ya||
– yStu rogivxe8): svRwE8Jykoivd:|
dexkalp/ma`)StSy isi²rs.xym||
(Caraka Sootra 20/21-22)
29. CONCLUSION
• Just anybody may use Ayurvedic medicines / plants / resources.
• But Ayurveda is Science Based Medicine and not Medicine Based
Science.
• We no more need new drugs, we need
reformed intelligence .
• xaS5a4R-kmaRnuxIlnens.SkuvIRtp/)am