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Viatmin Source Deficiency Function Toxicity Greater need if..
Thiamin B1 Whole grain, pork,
poultry, fish,
vegetable, dairy.
Wet Beri Beri (cardiac symptoms),
Dry Beri Beri (peripheral
neurophathy, gait) Wernicke-
Korsakoff, accumulation of lactate in
muscles
Co-enzyme in metabolic pathways.
(Pyruvate dehydrogenase)
Raw fish, coffee, tea,
alcohol (inhibits
absorbtion & enzyme
converting thiamin into
TPP), high carb,
polished rice
Riboflavin B2 Milk, protein In alcoholics (because of impaired
liver/storage), cataracts
FAD and FMN in redox Non-toxic
Niacin B3 Cereals,
converted from
tryptophan in
protein
Pellagra, photosensitive dermatitis,
diarrhoea, dementia
NAD and NADP in redox
Pantothenic
Acid B5
Ubiquitous Rare Component of Coenzyme A
Pyridoxine B6 Root and green
veg., supplements
given with
Isonazid
Isonazid (TB drug) Transamination, haem synthesis,
treatment of seizures, PMS, Downʼs,
autism
Peripheral
neuorpathy
Biotin B7 Peanuts,
chocolate, egg
yolk, gut flora
Rare Prosthetic group for pyruvate to
oxaloacetate (Krebs) and acetyl
CoA to malonyl Coa
Raw egg whites or long
term antibiotic therapy
(kills flora)
Folate B9 Green veg (active
as
tetrahydrofolate)
Results: Inadequate myelin
synthesis, neural tube defects
From: malabsorbtion, ethanol, drugs
(anti-convulsants)
Carrier of 1C units in metabolism,
DNA
Viatmin Source Deficiency Function Toxicity Greater need if..
Cobalamin
B12
Animal tissues Results in: pernicious anemia,
inadequate myelin synthesis.
From: Vegan diet, absent/defective
IF, coeliac disease, gastrectomy,
Carrier of methyl groups in
metabolism, conversion of
homocysteine to methionine, DNA,
needed for conversion of MeTHF
back to methotrexate (from B6),
needed for myelin synthesis
Vitamin C
(ascorbic acid)
RDI: 40mg
Citrus fruits,
berries, tomatoes
Scurvy (after 3 months with no vit.
C).
Anti-oxidant nutrient, collagen,
maintain Fe2+ state
Oxalate, kidney
stones,
diarrhoea
Smokers need 2x
Vitamin A
(retinol/
carotene)
Carrots, oils, milk,
egg yolk
Results: night blindness,
keratinisation of retina.
From: inadequate protein diets
Control of protein synthesis, in vision
at low light intensity.
Dermatitis, hair
loss, mucous
membrane
defects, liver
disfunction and
thinning of
bones
Vitamin E Vegetable oils,
wheat germ, nuts,
veg.
From: Depleted in frozen food
Results: Hemolytic anaemia due to
fragile RBC membranes
Antioxidant, membrane integrity
(against free radicals)
Vitamin D UV light, milk,
dairy
Rickets (bendy bones),
Osteomalacia (adult rickets)
Acts as steroid hormones, maintain
levels of calcium and phosphate in
the bones so they become
mineralised
hypercalcemia,
calcification of
soft tissues
(heart, lungs)
Vitamin K Green vegetables,
meat, eggs,
cereals, milk, gut
flora
From: long term antibiotic therapy
(destruction of gut flora).
Results: increased clotting time,
haemorrhagic disease of newborn

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Sc10 vitamins in 2 pages

  • 1. Viatmin Source Deficiency Function Toxicity Greater need if.. Thiamin B1 Whole grain, pork, poultry, fish, vegetable, dairy. Wet Beri Beri (cardiac symptoms), Dry Beri Beri (peripheral neurophathy, gait) Wernicke- Korsakoff, accumulation of lactate in muscles Co-enzyme in metabolic pathways. (Pyruvate dehydrogenase) Raw fish, coffee, tea, alcohol (inhibits absorbtion & enzyme converting thiamin into TPP), high carb, polished rice Riboflavin B2 Milk, protein In alcoholics (because of impaired liver/storage), cataracts FAD and FMN in redox Non-toxic Niacin B3 Cereals, converted from tryptophan in protein Pellagra, photosensitive dermatitis, diarrhoea, dementia NAD and NADP in redox Pantothenic Acid B5 Ubiquitous Rare Component of Coenzyme A Pyridoxine B6 Root and green veg., supplements given with Isonazid Isonazid (TB drug) Transamination, haem synthesis, treatment of seizures, PMS, Downʼs, autism Peripheral neuorpathy Biotin B7 Peanuts, chocolate, egg yolk, gut flora Rare Prosthetic group for pyruvate to oxaloacetate (Krebs) and acetyl CoA to malonyl Coa Raw egg whites or long term antibiotic therapy (kills flora) Folate B9 Green veg (active as tetrahydrofolate) Results: Inadequate myelin synthesis, neural tube defects From: malabsorbtion, ethanol, drugs (anti-convulsants) Carrier of 1C units in metabolism, DNA
  • 2. Viatmin Source Deficiency Function Toxicity Greater need if.. Cobalamin B12 Animal tissues Results in: pernicious anemia, inadequate myelin synthesis. From: Vegan diet, absent/defective IF, coeliac disease, gastrectomy, Carrier of methyl groups in metabolism, conversion of homocysteine to methionine, DNA, needed for conversion of MeTHF back to methotrexate (from B6), needed for myelin synthesis Vitamin C (ascorbic acid) RDI: 40mg Citrus fruits, berries, tomatoes Scurvy (after 3 months with no vit. C). Anti-oxidant nutrient, collagen, maintain Fe2+ state Oxalate, kidney stones, diarrhoea Smokers need 2x Vitamin A (retinol/ carotene) Carrots, oils, milk, egg yolk Results: night blindness, keratinisation of retina. From: inadequate protein diets Control of protein synthesis, in vision at low light intensity. Dermatitis, hair loss, mucous membrane defects, liver disfunction and thinning of bones Vitamin E Vegetable oils, wheat germ, nuts, veg. From: Depleted in frozen food Results: Hemolytic anaemia due to fragile RBC membranes Antioxidant, membrane integrity (against free radicals) Vitamin D UV light, milk, dairy Rickets (bendy bones), Osteomalacia (adult rickets) Acts as steroid hormones, maintain levels of calcium and phosphate in the bones so they become mineralised hypercalcemia, calcification of soft tissues (heart, lungs) Vitamin K Green vegetables, meat, eggs, cereals, milk, gut flora From: long term antibiotic therapy (destruction of gut flora). Results: increased clotting time, haemorrhagic disease of newborn