This document summarizes CGIAR research highlights from Latin America. It notes that while CGIAR investment in Latin America has diminished as focus has shifted to Africa and South Asia, the region remains important as a source of genetic resources, testing environments, and innovations like improved cassava processing and gender-responsive market approaches that provide lessons for global agriculture. Key accomplishments highlighted include identifying heat-tolerant sweetpotato varieties, monitoring the spread of Fusarium TR4 disease, developing optimized small-scale cassava dryers, and documenting high adoption of improved potato varieties in Peru. The implications discussed are maintaining a global CGIAR presence and leveraging Latin America's contributions to address global challenges like climate change.