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RELIANCE INSTITUTE OF NURSING
TOPIC
PRESENTED BY :-
MR. ROMAN BAJRANG
BASIC BS.C NURSING 2ND YEAR
RELIANCE INSTITUTE OF NURSING
Rickettsial Zoonoses
Introduction
 Rickettsial diseases are a group of infections caused by Gram negative bacteria of
the genus Rickettsia species.
 They are zoonotic infections that cause typhus and spotted fevers.
 Most rickettsial spotted fevers are transmitted to humans by ticks; typhus can be
transmitted by different vectors depending on the species of Rickettsia, most are
transmitted to humans by ticks.
 The exceptions are endemic (murine) typhus (R.typhi) which is transmitted by rat
fleas, epidemic typhus (R. prowazekii) which is transmitted by the human body louse
Pediculushumanus corporis, and scrub typhus (R. prowazekiitsutsugamushi) which
is transmitted by trombiculid mites.
 These last three diseases are seen more commonly in conditions of poverty and
crowding and are rare causes of illness in travellers.
 Those that have particular significance to travellers are African tick bite fever
(R.africae), boutonneuse fever (R.coronii) and Rocky Mountain spotted fever
(R.rickettsii), each of which is part of the spotted fever group of rickettsial diseases.
Transmission
 Most types of rickettsial disease are transmitted by several genera of ticks or other
arthropods, which take up the bacteria whilst feeding on infected animals.
 Reservoirs for African tick-bite fever include cattle, hippopotamus and rhinoceros.
 The bacteria are found in the salivary glands of the tick and are
transmitted while the tick takes a blood meal.
Signsand Symptoms
 The spotted fever group of rickettsial diseases are clinically similar. After
inoculation from a bite, a febrile illness develops following a short
incubation period of a few days that may persist for up to two weeks if
untreated.
 small ulcer
 A generalized rash develops involving the palms and soles of the feet.
 Oedema
 headache and chills
 fever
Diagnosis
 The laboratory diagnosis of rickettsial disease can be confirmed by
serology, antigen detection, or PCR usually after one or two weeks of
onset of illness.
 Diagnosis is therefore usually based on clinical signs and symptoms
following travel to a risk area, and confirmed once treatment has
commenced. Many travellers will not recall a tick bite.
Treatment
 Rickettsial disease responds to antibiotic therapy, with doxycycline being
the drug of choice.
Prevention
 There is no vaccine for rickettsial disease.
 Travellers should be encouraged to practice insect bite avoidance.
 begin to be inoculated into the human host.
 Travellers should inspect themselves regularly for ticks and remove them
promptly.
 Pets should also be inspected for ticks before allowing them to enter the
home.
THANKYOU

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Rickettsial zoonoses

  • 1. RELIANCE INSTITUTE OF NURSING TOPIC PRESENTED BY :- MR. ROMAN BAJRANG BASIC BS.C NURSING 2ND YEAR RELIANCE INSTITUTE OF NURSING
  • 2. Rickettsial Zoonoses Introduction  Rickettsial diseases are a group of infections caused by Gram negative bacteria of the genus Rickettsia species.  They are zoonotic infections that cause typhus and spotted fevers.  Most rickettsial spotted fevers are transmitted to humans by ticks; typhus can be transmitted by different vectors depending on the species of Rickettsia, most are transmitted to humans by ticks.  The exceptions are endemic (murine) typhus (R.typhi) which is transmitted by rat fleas, epidemic typhus (R. prowazekii) which is transmitted by the human body louse Pediculushumanus corporis, and scrub typhus (R. prowazekiitsutsugamushi) which is transmitted by trombiculid mites.  These last three diseases are seen more commonly in conditions of poverty and crowding and are rare causes of illness in travellers.  Those that have particular significance to travellers are African tick bite fever (R.africae), boutonneuse fever (R.coronii) and Rocky Mountain spotted fever (R.rickettsii), each of which is part of the spotted fever group of rickettsial diseases. Transmission  Most types of rickettsial disease are transmitted by several genera of ticks or other arthropods, which take up the bacteria whilst feeding on infected animals.  Reservoirs for African tick-bite fever include cattle, hippopotamus and rhinoceros.
  • 3.  The bacteria are found in the salivary glands of the tick and are transmitted while the tick takes a blood meal. Signsand Symptoms  The spotted fever group of rickettsial diseases are clinically similar. After inoculation from a bite, a febrile illness develops following a short incubation period of a few days that may persist for up to two weeks if untreated.  small ulcer  A generalized rash develops involving the palms and soles of the feet.  Oedema  headache and chills  fever Diagnosis  The laboratory diagnosis of rickettsial disease can be confirmed by serology, antigen detection, or PCR usually after one or two weeks of onset of illness.  Diagnosis is therefore usually based on clinical signs and symptoms following travel to a risk area, and confirmed once treatment has commenced. Many travellers will not recall a tick bite. Treatment  Rickettsial disease responds to antibiotic therapy, with doxycycline being the drug of choice. Prevention  There is no vaccine for rickettsial disease.
  • 4.  Travellers should be encouraged to practice insect bite avoidance.  begin to be inoculated into the human host.  Travellers should inspect themselves regularly for ticks and remove them promptly.  Pets should also be inspected for ticks before allowing them to enter the home. THANKYOU