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Indian Journal of Anaesthesia
Peer Review Guidelines For: Original Article/ Clinical Investigation
Points for Review Yes No
Headings
• Check for
- Title, Abstract, Key Words, Introduction, Methods, Results, Discussion,
Conclusion
- Conflicts of Interest / Permissions, References, Images/illustrations/videos
with legends (or legends for uploaded files)
Title
• Does it reflect the salient methodology, main outcome parameter, nature of the
study, groups involved with or without the outcome
• Can be a statement of the above or a simple question for or against the
hypothesis of outcome of the study
Abstract:
• A structured abstract
• Check for the subheadings: Background and Aims, Methods, Results,
Conclusion
• Background and Aims: Must mention the background related to the study-
what is already known on the proposed topic followed by the main aim of the
present study
• Methods –does it state the nature of the study (prospective/retrospective/
observational; randomised), type and number of sample / patients, intervention,
group allotment.
Does it state primary and secondary objectives, and a brief mention of the
salient statistical tests used
• Results – Does it state the total number of patients completing the study,
results related to the primary and secondary objectives along with actual P
values, any adverse events or complications?
• Conclusion – Is it based on the primary objective of the study?
• Word count of 250 and less only
Key words
• The Keywords are prepared after completion of manuscript preparation and
represent the most relevant and frequently used academic words in the article
• Check for 3-5 MeSH (Medical Short Headings) relevant to the article
Main Article
Introduction
• Check if a background for the study and the outcome is provided, citing
previous publications
• Upto max.6 references can be cited here, not more
• Does it provide the reason why this study is important for the reader
• Does it state the problem or literature vacuum or existing controversy?
• Does it state and end with the hypothesis or aim of the study?
Methods
• Institutional ethical committee / Institutional review board approval obtained?
• Written informed consent
• Where study was performed/ undertaken in terms of whether within the
hospital / outside, tertiary care hospital / teaching hospital, private nursing
home, clinic, pain clinic,etc (actual identity of hospital not allowed)
• Type of the study described clearly;observational,interventional,retrospective,
prospective,etc
• Inclusion and exclusion criteria: repetetion of the ‘inclusion criteria’ as not
being present in the exclusion criteria to be avoided (eg. ASA I & II as
inclusion criteria; ASA III,IV,V shall not be mentioned as exclusion criteria)
• Group allocation with the control / standard / placebo group as the first group,
the intervention group/ groups as the 2nd
/ 3rd
groups
• Check if the same sequence and nomenclature is maintained while the results
are mentioned/used in text, tables, graphs,etc
• Randomisation / allocation concealment / Blinding if used with details
• Clear description of flow of the study in all aspects starting from including the
patient in the study till completion of the study
• Methodology – is it designed to adequately test the hypothesis?
• Primary and secondary outcome parameters/ variables of the study are clearly
mentioned, described in terms of qualitative and quantitative tools and are the
same as in the abstract
• Check if the scoring systems/ grades/degrees,etc used are validated ones…new
ones by the author can not be allowed unless backed by big sample size
• If authors are using any unfamiliar tools for evaluation of the objectives – have
they provided detailed description of the tool?
• Frequency and duration of monitoring of the study parameters or follow up
clearly described
• Check for the basic and uniform anaesthesia management, use of standard
drugs and techniques, in all patients / both / all groups
• In studies involving general anaesthesia using analgesia as a parameter,
background analgesia is a must in all studies- not using one is unethical
• Mention of the rescue technique and drugs made or not?
Statistical analysis
• Last paragraph in the methods section
• Sample size and power calculation clearly detailed
• The sample size calculation should be based on the primary objective of the
study
• Mention of Statistical tests and which test for which results / outcomes at the
end of the study period (appropriateness of statistical tests)
• Software details mentioned (Name, version, year with brand name)
Results
• Demographic data are mentioned- no need for P values for age,weight,sex
unless the study is based on demographic variations
(Age,weight,sex are already part of inclusion and exclusion criteria; hence P
values are not needed. Only studies assessing change in a parameter with
height, weight, sex,etc need P values)
• States clearly number of patients selected, completed, dropouts (valid reasons
for dropouts)..encourage use of CONSORT Flow Diagram
• Statistics related to primary objective presented first and then other statistical
details are presented
• Results should only provide the facts related to the study and should NOT try
to explain or rationale the findings of the study. Have authors conformed to
this?
• Have the figures and tables (if any submitted) cited at appropriate places in the
results?
• Is the information in the figures/tables/abstract/results in any way different
from one another?
• Check if there is duplication of data in tables and graphs- not needed
• The order of mention of results in tables, graphs, illustrations,etc are in correct
sequence (control/ standard group first followed by intervention group) and
nomenclature is uniform
• The sequence of entry of results must be as per the sequence of outcome
parameters mentioned under Methods
• If images of apparatus / equipment are obtained from books, journals/
company monologues/other sources, the permission of the
Publishers/Companies is mandatory: this is author’s responsibility
Discussion
• Does it focus upon providing rationale for the findings of the study with more
emphasis on primary outcome parameter of the current study?
• The flow of discussion is of – what/why/how of the present study and then
compared to previous evidences
• Is the discussion of the outcome parameters in the same sequence as in the
abstract, methods, results
• No statement on the subject or statement containing figures / numbers related
to previous studies shall go without citation of those related references except
for widely known concepts
• Is the discussion of previous evidences accompanied by citation of those
references?……use of author names of previous studies discouraged; use in
indirect sentences is encouraged
• Study hypothesis: clearly declared and answered or not /substantiated (If not,
reasons for the same should be provided)
• Unbiased view of the strengths and weaknesses / limitations of the study to be
checked
(Authors may use discussion as a forum for suggesting how the future research can be
performed on the same topic overcoming the limitations of the present study)
Conclusion
• Shall be brief mention of the outcomes focussing of important aspects and
mentioning limitations
• Does it justify the results and is it based on the primary outcome variable?
• Shall not be more than 3 sentences
(Conclusion based on secondary objectives or suggesting future study or
recommending something should be discouraged – this is because, the study is not
powered adequately to answer the secondary objectives and hence could just be chance
findings; future study is necessary for every study and therefore, should not be part of
the conclusion; recommendations cannot be done through small scale studies – only
meta-analysis and systematic reviews may be able to come out with such things)
References
• Have the authors listed the references in Vancouver style?
• Have the authors updated their write up with latest references (from past 5-10
years)?
• Do the references and their citations in the text match with each other?
[(i).Often, during rewriting/rephrasing of articles – the authors end up citing
references in incorrect order resulting in reference being cited in inappropriate
places (ii). The citations are sometimes not relevant, related to drug,
concentration, technique,etc…please verify]
• Reference citations are not allowed in title / abstract and conclusions
• Ideally, the references should be only in introduction and discussion
• Methods section might require one or two references if authors are using some
tools for meaurement, etc from another source
• Discourage citation of only abstracts / incomplete references / references from
non-indexed sources / references from non-peer reviewed sources (e.g.,google,
newspapers, etc).
• For web references, check for entry of date of access
(Specific guidelines on style of entry of references are available at IJA website)
Images/illustrations/videos with legends (or legends for uploaded files)
• Check for relevance to the study
• Check for clarity / resolution
• For images: check if areas of interest are highlighted / pointed with arrows
For Reports: check if areas of interest are highlighted / pointed with arrows
• Schematic diagrams – are they well illustrated?
• Legends – are they self explanatory such that the reader should get maximum
information related to the figure from the legends?
• Check if tables contain proper units of measurement where applicable
• Patient / patient related images: Is anonymity/ identity concealment ensured?
(Information such as patient name, hospital number, etc should not be present)
• Cross check that patient consent for reproduction of images of patient,
tissues/organs, reports,etc are mentioned under methods
• Normally, only six (in total) images/graphs/illustrations are allowed
• Duplication of data in tables and graphs to be avoided
• Schematic diagrams – are they well illustrated?
• If multiple graphs are used – is the colour coding for groups the same in each
of them?
• Are the axes (X,Y,Z) for graphs properly and correctly labeled?
• Tables: Is each table accompanied by a clear caption that focus upon the
contents of the table (e.g., Table 2: Haemodynamic data at various study
intervals)
• Have the authors mentioned and cross checked correct entry of the total
number of patients in each group in each table? [e.g., group A (n = 30); group
B (n = 28)]..check for uniformity in all tables/ graphs
General Observations
• Make an overall evaluation of the article to see if group allocation and statistical details provided
in the abstract, methods, results, tables, figures are all the same
• Provide comments as a brief summary of the article
• List both the strengths and weaknesses of the article
• Provide specific assessment regarding title, abstract, subject contained under each
heading/subheading (discussed below)
• Provide assessment and scope for improvement in supplementary material such as tables / figures
• Please Note:
- The journal and the editors do not expect the reviewer to be competent at every aspect of the
article. Provide your honest opinion. Indicate clearly to the editor the areas in the article that you
are not confident of commenting on or suggest another individual who has knowledge in that area
(for e.g., statistics)
- If you feel there is no novelty or new message from the article – kindly try to provide reference to
substantiate your point
- Provide constructive suggestions if necessary for improving language, grammar, style of
presentation with one or two examples
“IJA intends to promote and encourage scientific writing and publications…..balancing with need for
quality publications”	
• Upload the information related to following aspects in the comments to the editor section and
NOT in the author’s area
§ Issues related to possible plagiarism or copyright issues or inadequate protection
of human subjects
§ Your decision on the article - accept/reject/revise OR possible recommendation
on changing to another type of submission (e.g., original investigation to a brief
report, etc)
§ Be mindful of the language used in the assessment to authors, criticize the article
but not the author

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Review roleija originalstudy

  • 1. Indian Journal of Anaesthesia Peer Review Guidelines For: Original Article/ Clinical Investigation Points for Review Yes No Headings • Check for - Title, Abstract, Key Words, Introduction, Methods, Results, Discussion, Conclusion - Conflicts of Interest / Permissions, References, Images/illustrations/videos with legends (or legends for uploaded files) Title • Does it reflect the salient methodology, main outcome parameter, nature of the study, groups involved with or without the outcome • Can be a statement of the above or a simple question for or against the hypothesis of outcome of the study Abstract: • A structured abstract • Check for the subheadings: Background and Aims, Methods, Results, Conclusion • Background and Aims: Must mention the background related to the study- what is already known on the proposed topic followed by the main aim of the present study • Methods –does it state the nature of the study (prospective/retrospective/ observational; randomised), type and number of sample / patients, intervention, group allotment. Does it state primary and secondary objectives, and a brief mention of the salient statistical tests used • Results – Does it state the total number of patients completing the study, results related to the primary and secondary objectives along with actual P values, any adverse events or complications? • Conclusion – Is it based on the primary objective of the study? • Word count of 250 and less only Key words • The Keywords are prepared after completion of manuscript preparation and represent the most relevant and frequently used academic words in the article • Check for 3-5 MeSH (Medical Short Headings) relevant to the article
  • 2. Main Article Introduction • Check if a background for the study and the outcome is provided, citing previous publications • Upto max.6 references can be cited here, not more • Does it provide the reason why this study is important for the reader • Does it state the problem or literature vacuum or existing controversy? • Does it state and end with the hypothesis or aim of the study? Methods • Institutional ethical committee / Institutional review board approval obtained? • Written informed consent • Where study was performed/ undertaken in terms of whether within the hospital / outside, tertiary care hospital / teaching hospital, private nursing home, clinic, pain clinic,etc (actual identity of hospital not allowed) • Type of the study described clearly;observational,interventional,retrospective, prospective,etc • Inclusion and exclusion criteria: repetetion of the ‘inclusion criteria’ as not being present in the exclusion criteria to be avoided (eg. ASA I & II as inclusion criteria; ASA III,IV,V shall not be mentioned as exclusion criteria) • Group allocation with the control / standard / placebo group as the first group, the intervention group/ groups as the 2nd / 3rd groups • Check if the same sequence and nomenclature is maintained while the results are mentioned/used in text, tables, graphs,etc • Randomisation / allocation concealment / Blinding if used with details • Clear description of flow of the study in all aspects starting from including the patient in the study till completion of the study • Methodology – is it designed to adequately test the hypothesis? • Primary and secondary outcome parameters/ variables of the study are clearly mentioned, described in terms of qualitative and quantitative tools and are the same as in the abstract • Check if the scoring systems/ grades/degrees,etc used are validated ones…new ones by the author can not be allowed unless backed by big sample size • If authors are using any unfamiliar tools for evaluation of the objectives – have they provided detailed description of the tool? • Frequency and duration of monitoring of the study parameters or follow up clearly described • Check for the basic and uniform anaesthesia management, use of standard drugs and techniques, in all patients / both / all groups • In studies involving general anaesthesia using analgesia as a parameter, background analgesia is a must in all studies- not using one is unethical • Mention of the rescue technique and drugs made or not? Statistical analysis • Last paragraph in the methods section • Sample size and power calculation clearly detailed
  • 3. • The sample size calculation should be based on the primary objective of the study • Mention of Statistical tests and which test for which results / outcomes at the end of the study period (appropriateness of statistical tests) • Software details mentioned (Name, version, year with brand name) Results • Demographic data are mentioned- no need for P values for age,weight,sex unless the study is based on demographic variations (Age,weight,sex are already part of inclusion and exclusion criteria; hence P values are not needed. Only studies assessing change in a parameter with height, weight, sex,etc need P values) • States clearly number of patients selected, completed, dropouts (valid reasons for dropouts)..encourage use of CONSORT Flow Diagram • Statistics related to primary objective presented first and then other statistical details are presented • Results should only provide the facts related to the study and should NOT try to explain or rationale the findings of the study. Have authors conformed to this? • Have the figures and tables (if any submitted) cited at appropriate places in the results? • Is the information in the figures/tables/abstract/results in any way different from one another? • Check if there is duplication of data in tables and graphs- not needed • The order of mention of results in tables, graphs, illustrations,etc are in correct sequence (control/ standard group first followed by intervention group) and nomenclature is uniform • The sequence of entry of results must be as per the sequence of outcome parameters mentioned under Methods • If images of apparatus / equipment are obtained from books, journals/ company monologues/other sources, the permission of the Publishers/Companies is mandatory: this is author’s responsibility Discussion • Does it focus upon providing rationale for the findings of the study with more emphasis on primary outcome parameter of the current study? • The flow of discussion is of – what/why/how of the present study and then compared to previous evidences • Is the discussion of the outcome parameters in the same sequence as in the abstract, methods, results • No statement on the subject or statement containing figures / numbers related to previous studies shall go without citation of those related references except for widely known concepts
  • 4. • Is the discussion of previous evidences accompanied by citation of those references?……use of author names of previous studies discouraged; use in indirect sentences is encouraged • Study hypothesis: clearly declared and answered or not /substantiated (If not, reasons for the same should be provided) • Unbiased view of the strengths and weaknesses / limitations of the study to be checked (Authors may use discussion as a forum for suggesting how the future research can be performed on the same topic overcoming the limitations of the present study) Conclusion • Shall be brief mention of the outcomes focussing of important aspects and mentioning limitations • Does it justify the results and is it based on the primary outcome variable? • Shall not be more than 3 sentences (Conclusion based on secondary objectives or suggesting future study or recommending something should be discouraged – this is because, the study is not powered adequately to answer the secondary objectives and hence could just be chance findings; future study is necessary for every study and therefore, should not be part of the conclusion; recommendations cannot be done through small scale studies – only meta-analysis and systematic reviews may be able to come out with such things) References • Have the authors listed the references in Vancouver style? • Have the authors updated their write up with latest references (from past 5-10 years)? • Do the references and their citations in the text match with each other? [(i).Often, during rewriting/rephrasing of articles – the authors end up citing references in incorrect order resulting in reference being cited in inappropriate places (ii). The citations are sometimes not relevant, related to drug, concentration, technique,etc…please verify] • Reference citations are not allowed in title / abstract and conclusions • Ideally, the references should be only in introduction and discussion • Methods section might require one or two references if authors are using some tools for meaurement, etc from another source • Discourage citation of only abstracts / incomplete references / references from non-indexed sources / references from non-peer reviewed sources (e.g.,google, newspapers, etc). • For web references, check for entry of date of access
  • 5. (Specific guidelines on style of entry of references are available at IJA website) Images/illustrations/videos with legends (or legends for uploaded files) • Check for relevance to the study • Check for clarity / resolution • For images: check if areas of interest are highlighted / pointed with arrows For Reports: check if areas of interest are highlighted / pointed with arrows • Schematic diagrams – are they well illustrated? • Legends – are they self explanatory such that the reader should get maximum information related to the figure from the legends? • Check if tables contain proper units of measurement where applicable • Patient / patient related images: Is anonymity/ identity concealment ensured? (Information such as patient name, hospital number, etc should not be present) • Cross check that patient consent for reproduction of images of patient, tissues/organs, reports,etc are mentioned under methods • Normally, only six (in total) images/graphs/illustrations are allowed • Duplication of data in tables and graphs to be avoided • Schematic diagrams – are they well illustrated? • If multiple graphs are used – is the colour coding for groups the same in each of them? • Are the axes (X,Y,Z) for graphs properly and correctly labeled? • Tables: Is each table accompanied by a clear caption that focus upon the contents of the table (e.g., Table 2: Haemodynamic data at various study intervals) • Have the authors mentioned and cross checked correct entry of the total number of patients in each group in each table? [e.g., group A (n = 30); group B (n = 28)]..check for uniformity in all tables/ graphs General Observations • Make an overall evaluation of the article to see if group allocation and statistical details provided in the abstract, methods, results, tables, figures are all the same • Provide comments as a brief summary of the article • List both the strengths and weaknesses of the article • Provide specific assessment regarding title, abstract, subject contained under each heading/subheading (discussed below) • Provide assessment and scope for improvement in supplementary material such as tables / figures • Please Note: - The journal and the editors do not expect the reviewer to be competent at every aspect of the article. Provide your honest opinion. Indicate clearly to the editor the areas in the article that you are not confident of commenting on or suggest another individual who has knowledge in that area (for e.g., statistics) - If you feel there is no novelty or new message from the article – kindly try to provide reference to substantiate your point - Provide constructive suggestions if necessary for improving language, grammar, style of presentation with one or two examples
  • 6. “IJA intends to promote and encourage scientific writing and publications…..balancing with need for quality publications” • Upload the information related to following aspects in the comments to the editor section and NOT in the author’s area § Issues related to possible plagiarism or copyright issues or inadequate protection of human subjects § Your decision on the article - accept/reject/revise OR possible recommendation on changing to another type of submission (e.g., original investigation to a brief report, etc) § Be mindful of the language used in the assessment to authors, criticize the article but not the author