This is the presentation depicting the major catabolic effects and the various hormones responsible for increasing the concentration of Glucose in blood stream in times of stress and starvation.

1. Regulationof BloodGlucose
(Part-II)
Dr. Abhishek Roy
JR, Dept. of Biochemistry
Grant Govt. Medical College and
Sir JJ Group of Hospitals, Mumbai
Email: mail@abhishek.ro

3. Main effects of Growth Hormone

4. Main effects of Epinephrine

5. Main effects of Glucocorticoids

8. Enzyme induction and repression by Glucagon
Glu-6-Pase +
Fruc-1,6- BPase +
PEPCK +
Glucokinase -
PFK-1 -
Pyruvate Kinase -

17. Variation in glucose phosphorylating activity of hexokinase and glucokinase with increasing blood glucose
concentration.The Km for glucose of hexokinase is 0.05 mmol/L and of glucokinase is 10 mmol/L.

20. Control Of Glycogen Synthase in muscle

21. Control of Phosphorylase in Muscle

23. Cori’s Cycle (Lactate Cycle) and Glucose-Alanine Cycle

25. Triacylglycerol metabolism in adipose tissue. Hormone-
sensitive lipase is activated by ACTH,TSH, glucagon,
epinephrine, norepinephrine, and vasopressin and inhibited by
insulin, prostaglandin E1 , and nicotinic acid.
Lipolysis

26. Lipolysis

27. Ketogenesis