(1) The patient is a 75-year-old female who presented with left lower quadrant pain, decreased bowel movements, weight loss, and recent vomiting of coffee ground material. (2) Physical exam revealed abdominal tenderness and a palpable mass in the left lower quadrant. (3) Imaging showed features suggestive of a colorectal mass. (4) During surgery, a rectosigmoid mass was found involving nearby structures, consistent with stage IV rectal cancer. (5) The patient underwent a Hartmann's procedure and ileostomy for palliation of bowel obstruction from metastatic rectal cancer.
A 13-year-old boy presented with sore throat and fever initially, followed by vague abdominal pain, loss of appetite, and vomiting. On examination, he had marked tenderness in the right lower abdomen. Imaging showed an inflamed appendix. He was diagnosed with acute appendicitis.
The appendix is a vestigial tube connected to the cecum. Acute appendicitis is commonly caused by obstruction of the appendix and bacterial proliferation. It presents with initial vague abdominal pain that later localizes to the right lower abdomen. Examination findings include tenderness and rebound tenderness over McBurney's point. Alvarado scoring helps determine risk of appendicitis. Treatment is surgical appendectomy,
This document discusses various types of intestinal obstructions in neonates. It describes high intestinal obstructions, which occur proximal to the ileum such as gastric, duodenal or jejunal obstructions. It also describes low intestinal obstructions, which occur distal to the ileum and in the colon. Specific causes of obstruction discussed include duodenal atresia, intestinal malrotation, necrotizing enterocolitis, meconium ileus and Hirschsprung's disease. Diagnosis involves abdominal x-rays and contrast studies to identify the location and cause of obstruction.
This document provides information on umbilical, paraumbilical, and incisional hernias. It discusses the anatomy, classification, features, and treatment options for each type of hernia. Umbilical hernias are common in newborns and infants and can be congenital or acquired. Paraumbilical hernias typically present as swellings in adults, especially females. Incisional hernias occur through weak surgical scars from prior abdominal operations. All three types are generally treated with surgical repair or mesh placement, depending on hernia size and characteristics.
Gastrointestinal stromal tumors (GISTs) are rare sarcomas that arise from the gastrointestinal tract. Most commonly found in the stomach, they represent 0.2% of gastrointestinal tumors. While often asymptomatic, they can present with bleeding, pain, or obstruction. Diagnosis involves imaging such as endoscopy or CT scan followed by biopsy showing immunohistochemistry positive for CD117 in 95% of cases. Treatment involves surgical resection with clear margins although adjuvant therapy with imatinib is often used for higher risk tumors. Outcomes have improved greatly in the past two decades with 5-year survival rates now over 50% with appropriate treatment.
This is a detailed lecture about different complications of Hernia and their management. Including; Irreducible, obstructed, strangulated, incarcerated hernia.
Intestinal obstruction in children can have several causes including duodenal hematoma from blunt trauma or bleeding disorders, duplication cysts appearing as cystic masses on imaging, and Meckel's diverticulum which can cause bleeding or intussusception. Appendicitis presents with abdominal pain localized to the right lower quadrant. Henoch-Schonlein purpura causes small bowel vasculitis and presents with abdominal pain and rash. Imaging can identify thickened bowel loops, free fluid, and inflamed lymph nodes in appendicitis or bowel wall thickening in other causes of obstruction. Intussusception is a common cause in infants appearing as a soft tissue mass on x-ray or concentric rings on
Mr. T, a 56-year-old man, presented with acute pancreatitis symptoms including epigastric pain and nausea. Investigations confirmed elevated pancreatic enzymes. He was initially treated conservatively but his condition deteriorated, requiring ICU admission and intubation. Imaging showed acute pancreatitis with peripancreatic fluid collection. Antibiotics were started after he developed a fever. Complications of acute pancreatitis like pancreatic necrosis and pseudocyst formation were discussed. The role of antibiotics, ERCP, and surgical or radiologic drainage of infected collections was also outlined.
This case presents a 65-year-old female with bilateral mid-back pain, fatigue, loss of appetite, and vomiting. Physical exam revealed tenderness in the right upper quadrant. Labs showed elevated liver enzymes and bilirubin. Imaging found gallstones and a dilated common bile duct. The diagnosis was choledocholithiasis, which was confirmed on MRCP. The patient underwent ERCP for stone removal and laparoscopic cholecystectomy. Though she initially presented with only back pain, further workup revealed an obstructed common bile duct due to gallstones.
A 13-year-old boy presented with sore throat and fever initially, followed by vague abdominal pain, loss of appetite, and vomiting. On examination, he had marked tenderness in the right lower abdomen. Imaging showed an inflamed appendix. He was diagnosed with acute appendicitis.
The appendix is a vestigial tube connected to the cecum. Acute appendicitis is commonly caused by obstruction of the appendix and bacterial proliferation. It presents with initial vague abdominal pain that later localizes to the right lower abdomen. Examination findings include tenderness and rebound tenderness over McBurney's point. Alvarado scoring helps determine risk of appendicitis. Treatment is surgical appendectomy,
This document discusses various types of intestinal obstructions in neonates. It describes high intestinal obstructions, which occur proximal to the ileum such as gastric, duodenal or jejunal obstructions. It also describes low intestinal obstructions, which occur distal to the ileum and in the colon. Specific causes of obstruction discussed include duodenal atresia, intestinal malrotation, necrotizing enterocolitis, meconium ileus and Hirschsprung's disease. Diagnosis involves abdominal x-rays and contrast studies to identify the location and cause of obstruction.
This document provides information on umbilical, paraumbilical, and incisional hernias. It discusses the anatomy, classification, features, and treatment options for each type of hernia. Umbilical hernias are common in newborns and infants and can be congenital or acquired. Paraumbilical hernias typically present as swellings in adults, especially females. Incisional hernias occur through weak surgical scars from prior abdominal operations. All three types are generally treated with surgical repair or mesh placement, depending on hernia size and characteristics.
Gastrointestinal stromal tumors (GISTs) are rare sarcomas that arise from the gastrointestinal tract. Most commonly found in the stomach, they represent 0.2% of gastrointestinal tumors. While often asymptomatic, they can present with bleeding, pain, or obstruction. Diagnosis involves imaging such as endoscopy or CT scan followed by biopsy showing immunohistochemistry positive for CD117 in 95% of cases. Treatment involves surgical resection with clear margins although adjuvant therapy with imatinib is often used for higher risk tumors. Outcomes have improved greatly in the past two decades with 5-year survival rates now over 50% with appropriate treatment.
This is a detailed lecture about different complications of Hernia and their management. Including; Irreducible, obstructed, strangulated, incarcerated hernia.
Intestinal obstruction in children can have several causes including duodenal hematoma from blunt trauma or bleeding disorders, duplication cysts appearing as cystic masses on imaging, and Meckel's diverticulum which can cause bleeding or intussusception. Appendicitis presents with abdominal pain localized to the right lower quadrant. Henoch-Schonlein purpura causes small bowel vasculitis and presents with abdominal pain and rash. Imaging can identify thickened bowel loops, free fluid, and inflamed lymph nodes in appendicitis or bowel wall thickening in other causes of obstruction. Intussusception is a common cause in infants appearing as a soft tissue mass on x-ray or concentric rings on
Mr. T, a 56-year-old man, presented with acute pancreatitis symptoms including epigastric pain and nausea. Investigations confirmed elevated pancreatic enzymes. He was initially treated conservatively but his condition deteriorated, requiring ICU admission and intubation. Imaging showed acute pancreatitis with peripancreatic fluid collection. Antibiotics were started after he developed a fever. Complications of acute pancreatitis like pancreatic necrosis and pseudocyst formation were discussed. The role of antibiotics, ERCP, and surgical or radiologic drainage of infected collections was also outlined.
This case presents a 65-year-old female with bilateral mid-back pain, fatigue, loss of appetite, and vomiting. Physical exam revealed tenderness in the right upper quadrant. Labs showed elevated liver enzymes and bilirubin. Imaging found gallstones and a dilated common bile duct. The diagnosis was choledocholithiasis, which was confirmed on MRCP. The patient underwent ERCP for stone removal and laparoscopic cholecystectomy. Though she initially presented with only back pain, further workup revealed an obstructed common bile duct due to gallstones.
Carcinoids are rare neuroendocrine tumors that originate from enterochromaffin cells. They most commonly occur in the gastrointestinal tract and bronchopulmonary system. Carcinoids are classified based on their site of origin and pathological features. Well differentiated carcinoids tend to grow slowly, while poorly differentiated carcinoids are more aggressive. Treatment involves surgical removal of localized tumors. For metastatic disease, treatment focuses on controlling carcinoid syndrome symptoms caused by secreted hormones and peptides. Prognosis depends on tumor stage, grade, and site of origin. Long term monitoring is important after treatment due to the risk of recurrence.
1. An umbilical hernia is a protrusion of abdominal contents through the abdominal wall near the umbilicus.
2. It can be congenital, due to incomplete closure of the umbilical ring, or acquired later in life due to risk factors like obesity, pregnancy, or ascites.
3. Physical exam reveals a soft, reducible mass at the umbilicus that increases in size with straining; complications include incarceration or strangulation which require surgery.
Dr. Shirish Silwal provides a summary of different types of hernias including inguinal, umbilical, paraumbilical, incisional, epigastric, spigelian, and lumbar hernias. The document discusses the history, anatomy, causes, presentations, complications, and management approaches for each hernia type. Meshes are recommended for repair when there is a large defect size, multiple defects, or lax abdominal walls to create a tension-free repair and reduce recurrence rates.
OPEN INGUINAL HERNIA REPAIR- OPERATIVE SURGERY
#surgicaleducator #operativesurgery #openinguinalherniarepair #usmle #babysurgeon #surgicaltutor
Dear viewers,
• Greetings from “Surgical Educator”
• Because of the popular demand by viewers of the YouTube channel “Surgical Educator”, I have decided to create and upload videos on common surgeries.
• I have already uploaded videos on open and Laparoscopic Appendicectomy, Thyroidectomy, Modified Radical Mastectomy and open and
Laparoscopic Cholecystectomy
• In this video today, I have discussed Open Inguinal Hernia Repair.
• However, these videos are not real surgeries but the theoretical aspect of operative surgery like going through an atlas of operative surgery.
• Along with these videos, I recommend you to watch real operative surgery videos as well and I will give a link for each surgery in the end of the video as end-cards, which I think will be very useful.
• This will give a very good opportunity for the surgical trainees to mentally rehearse various surgical steps in a sequential manner prior to actual surgery. You can watch the video in the following links:
• surgicaleducator.blogspot.com
• youtube.com/c/surgicaleducator
• Thank you for watching the videos.
1. The document describes an OSCE sample case involving an inguinoscrotal swelling. It provides differential diagnoses, classifications of hydrocele, and treatment approaches.
2. It also describes a case of undescended testes, including factors affecting testicular descent, treatment, and complications.
3. Additional cases include a hemangioma, hypospadias, and cleft lip, with descriptions of presentations, classifications, treatments and associated issues.
OPEN CHOLECYSTECTOMY- OPERATIVE SURGERY
#surgicaleducator #operativesurgery #opencholecystectomy #usmle #babysurgeon #surgicaltutor
Dear viewers,
• Greetings from “Surgical Educator”
• Because of the popular demand by viewers of the YouTube channel “Surgical Educator”, I have decided to create and upload videos on common surgeries.
• I have already uploaded videos on open and Laparoscopic Appendicectomy, Thyroidectomy and Modified Radical Mastectomy.
• In this video today, I have discussed Open Cholecystectomy.
• However, these videos are not real surgeries but the theoretical aspect of operative surgery like going through an atlas of operative surgery.
• Along with these videos, I recommend you to watch real operative surgery videos as well and I will give a link for each surgery in the end of the video as end-cards, which I think will be very useful.
• This will give a very good opportunity for the surgical trainees to mentally rehearse various surgical steps in a sequential manner prior to actual surgery. You can watch the video in the following links:
• surgicaleducator.blogspot.com
• youtube.com/c/surgicaleducator
• Thank you for watching the videos.
INVESTIGATIONS OF A PATIENT WITH OBSTRUCTIVE JAUNDICE -LETS GODr.Manojit Sarkar
Routine tests like liver function tests, urine analysis, and hematological investigations are used to determine if a patient's symptoms suggest obstructive jaundice. Imaging tests like ultrasound, MRCP, ERCP, and CT scan help locate the cause by visualizing the biliary tree and detecting any dilations, masses, or other abnormalities. ERCP can both diagnose the specific cause by visualizing structures and performing biopsies and also treat certain conditions like gallstones through procedures such as sphincterotomy and stent placement. The combination of biochemical and imaging tests aims to determine if the jaundice has an obstructive etiology, identify suspected causes like cancer or gallstones, and assess if the patient is a surgical candidate.
- Anorectal malformations (ARMs) range from minor defects to complex anomalies associated with other issues. They occur in approximately 1 in 5,000 births.
- Evaluation of newborns with ARMs involves examining the anus, genitals, and spine. Imaging studies like ultrasound, MRI and contrast enemas are used to characterize the anatomy and identify any associated anomalies in other organ systems.
- Treatment depends on the specific type of ARM, but may involve procedures like colostomy to allow the distal anatomy to develop before definitive repair. The long-term goals are to establish bowel and urinary continence.
This document contains summaries of various medical cases involving different conditions:
1) Burns on legs presenting complications of wound contractures, scarring, infection, shock, and renal failure.
2) Breast cancer case describing T staging of TNM and clinical types including phylloides tumor, invasive ductal carcinoma, ductal carcinoma in situ, and medullary carcinoma.
3) Thyroid lump involving a multinodular goiter case discussing workup before surgery.
This document discusses breast lumps and the evaluation process. It covers the anatomy of the breast, history taking, clinical examination techniques, and the "triple assessment" process of ultrasound, mammography, and biopsy to establish a diagnosis. The anatomy section describes the structure of the breast including lobes, ducts, and lymphatic drainage. The examination section provides details on inspecting and palpating the breasts and lymph nodes. The triple assessment discusses the use of imaging like ultrasound and mammography as well as biopsy techniques to diagnose breast lumps.
This document discusses abdominal wall defects, specifically omphalocele and gastroschisis. Omphalocele is a birth defect where abdominal organs protrude out of the belly button, which is covered by a sac-like membrane. Gastroschisis is where the intestines protrude out of the abdominal wall to the right of the umbilical cord without a protective sac. Prenatal ultrasound can diagnose these conditions. Treatment for omphalocele may involve conservative management with a sac or surgical closure, while gastroschisis typically requires primary closure. Long-term outcomes depend on the severity of the defect and presence of other anomalies, with generally good prognosis if no other issues are present.
1. Obstructive jaundice results from obstruction of bile flow from the liver to the duodenum, causing bilirubin levels to rise above 2.5mg/dL and resulting in jaundice.
2. The top 3 causes of obstructive jaundice are choledocholithiasis, strictures, and pancreatic cancer.
3. Evaluation involves clinical examination, blood tests of liver function and markers, ultrasound of the bile ducts, and CT or ERCP to visualize the biliary tree and determine the level and cause of obstruction.
This document provides an overview of duodenal atresia, including its definition, epidemiology, etiology, clinical features, diagnosis, management, complications, and differential diagnosis. Duodenal atresia is a congenital absence or closure of part of the duodenum due to defective fusion during development. It commonly presents after birth with vomiting, jaundice, and abdominal distension. Diagnosis is typically made through imaging findings like the "double bubble" sign on x-ray. Surgical management involves bypassing the blocked portion of duodenum through procedures like duodenoduodenostomy. Complications can include anastomotic issues or problems from associated anomalies.
1. A 60-year-old male presented with yellowish discoloration of the eye, itching all over the body, pale stools, loss of appetite, and weight loss.
2. Obstructive jaundice and periampullary carcinoma were suspected given his age, painless progressive jaundice, pruritis, pale stools, and weight loss.
3. Key clinical features of obstructive jaundice include jaundice, intense pruritis, pale stools, loss of appetite and weight in patients typically aged 50-70 years.
This document discusses the differential diagnosis of neck swellings. It begins by defining a neck mass and differential diagnosis. It then describes the various structures that can cause swellings in the head and neck region, including lymph nodes, salivary glands, and muscles. The document outlines the approach to examining a neck mass, including inspecting for location, size, and color, and palpating for tenderness, size, and mobility. Radiographic investigations like MRI, CT, and ultrasound are discussed. Biopsy methods like fine needle aspiration are also summarized.
Choledochal cyst is a rare congenital dilatation of the bile duct that occurs in 1 in 100,000 people. It is more common in Asian populations and women. The pathogenesis is typically due to an anomalous pancreaticobiliary junction, where the pancreatic and biliary ducts fuse before entering the duodenum. This allows pancreatic secretions to reflux into the bile duct and cause inflammation and cystic degeneration. Choledochal cysts are classified into 5 types based on their location and extent. Patients typically present with jaundice, right upper quadrant pain, or a palpable mass. Investigations include ultrasound, CT, MRCP and ERCP to establish the diagnosis and classification. Complications include
Carcinoid tumors are slow-growing neuroendocrine tumors that commonly arise in the gastrointestinal tract and lungs. The document discusses carcinoid tumors in depth, including their definition, sites of origin, histology, staging, clinical features, diagnostic testing, and management approaches. Treatment involves surgical resection when possible, with additional therapies for advanced or metastatic disease aimed at controlling hormone secretion and tumor growth.
1. The document discusses various potential causes of a mass in the right iliac fossa, including appendicitis, appendicular abscess, carcinoid tumors of the appendix, mucoceles, adenocarcinoma, tuberculosis, Crohn's disease, carcinoma of the caecum, actinomycosis, amoebiasis, mesenteric cysts, intussusception, iliopsoas abscess, retroperitoneal tumors, aneurysms, and more rare causes.
2. Diagnostic tools mentioned include ultrasound, CT, colonoscopy, and biopsy. Treatment depends on the underlying cause but may include antibiotics, surgery, chemotherapy, and ATT.
3
This document discusses the management and treatment of hydrocele. It outlines the necessary investigations which may include blood tests, urine tests, and chest x-rays. Ultrasound is helpful for determining testis position and abnormalities. Fluid aspiration can indicate different conditions. Surgical procedures like lord's plication and Jaboulay's operation are described for fixing different types of hydroceles. Post-operative care and potential complications are also covered. The document provides an overview of evaluating and treating hydroceles.
focal nodular hyprplasia FNH case PRESENTATIONChinmay Mehta
A 40-year-old woman presented with abdominal pain and hypotension. Imaging found a large liver lesion and hemorrhagic fluid in the peritoneum. Differentials included ruptured ectopic pregnancy or hepatic tumor. CT showed an encapsulated heterogeneous liver lesion involving the left lobe with normal vasculature. Follow up CT showed resolution of ascites without change in the liver lesion. MRI was suggestive of focal nodular hyperplasia (FNH) based on enhancement patterns. Treatment options for FNH include observation, ablation, embolization, or excision.
Gastric cancer seminar presentation covered the following topics in 3 sentences or less:
The presentation discussed the anatomy, blood supply, lymphatic drainage and histology of the stomach. Risk factors, clinical presentation, diagnostic tools and staging of gastric cancer were explained. Surgical treatment options including endoscopic resection, gastrectomy and lymph node dissection were summarized along with reconstruction methods.
Carcinoids are rare neuroendocrine tumors that originate from enterochromaffin cells. They most commonly occur in the gastrointestinal tract and bronchopulmonary system. Carcinoids are classified based on their site of origin and pathological features. Well differentiated carcinoids tend to grow slowly, while poorly differentiated carcinoids are more aggressive. Treatment involves surgical removal of localized tumors. For metastatic disease, treatment focuses on controlling carcinoid syndrome symptoms caused by secreted hormones and peptides. Prognosis depends on tumor stage, grade, and site of origin. Long term monitoring is important after treatment due to the risk of recurrence.
1. An umbilical hernia is a protrusion of abdominal contents through the abdominal wall near the umbilicus.
2. It can be congenital, due to incomplete closure of the umbilical ring, or acquired later in life due to risk factors like obesity, pregnancy, or ascites.
3. Physical exam reveals a soft, reducible mass at the umbilicus that increases in size with straining; complications include incarceration or strangulation which require surgery.
Dr. Shirish Silwal provides a summary of different types of hernias including inguinal, umbilical, paraumbilical, incisional, epigastric, spigelian, and lumbar hernias. The document discusses the history, anatomy, causes, presentations, complications, and management approaches for each hernia type. Meshes are recommended for repair when there is a large defect size, multiple defects, or lax abdominal walls to create a tension-free repair and reduce recurrence rates.
OPEN INGUINAL HERNIA REPAIR- OPERATIVE SURGERY
#surgicaleducator #operativesurgery #openinguinalherniarepair #usmle #babysurgeon #surgicaltutor
Dear viewers,
• Greetings from “Surgical Educator”
• Because of the popular demand by viewers of the YouTube channel “Surgical Educator”, I have decided to create and upload videos on common surgeries.
• I have already uploaded videos on open and Laparoscopic Appendicectomy, Thyroidectomy, Modified Radical Mastectomy and open and
Laparoscopic Cholecystectomy
• In this video today, I have discussed Open Inguinal Hernia Repair.
• However, these videos are not real surgeries but the theoretical aspect of operative surgery like going through an atlas of operative surgery.
• Along with these videos, I recommend you to watch real operative surgery videos as well and I will give a link for each surgery in the end of the video as end-cards, which I think will be very useful.
• This will give a very good opportunity for the surgical trainees to mentally rehearse various surgical steps in a sequential manner prior to actual surgery. You can watch the video in the following links:
• surgicaleducator.blogspot.com
• youtube.com/c/surgicaleducator
• Thank you for watching the videos.
1. The document describes an OSCE sample case involving an inguinoscrotal swelling. It provides differential diagnoses, classifications of hydrocele, and treatment approaches.
2. It also describes a case of undescended testes, including factors affecting testicular descent, treatment, and complications.
3. Additional cases include a hemangioma, hypospadias, and cleft lip, with descriptions of presentations, classifications, treatments and associated issues.
OPEN CHOLECYSTECTOMY- OPERATIVE SURGERY
#surgicaleducator #operativesurgery #opencholecystectomy #usmle #babysurgeon #surgicaltutor
Dear viewers,
• Greetings from “Surgical Educator”
• Because of the popular demand by viewers of the YouTube channel “Surgical Educator”, I have decided to create and upload videos on common surgeries.
• I have already uploaded videos on open and Laparoscopic Appendicectomy, Thyroidectomy and Modified Radical Mastectomy.
• In this video today, I have discussed Open Cholecystectomy.
• However, these videos are not real surgeries but the theoretical aspect of operative surgery like going through an atlas of operative surgery.
• Along with these videos, I recommend you to watch real operative surgery videos as well and I will give a link for each surgery in the end of the video as end-cards, which I think will be very useful.
• This will give a very good opportunity for the surgical trainees to mentally rehearse various surgical steps in a sequential manner prior to actual surgery. You can watch the video in the following links:
• surgicaleducator.blogspot.com
• youtube.com/c/surgicaleducator
• Thank you for watching the videos.
INVESTIGATIONS OF A PATIENT WITH OBSTRUCTIVE JAUNDICE -LETS GODr.Manojit Sarkar
Routine tests like liver function tests, urine analysis, and hematological investigations are used to determine if a patient's symptoms suggest obstructive jaundice. Imaging tests like ultrasound, MRCP, ERCP, and CT scan help locate the cause by visualizing the biliary tree and detecting any dilations, masses, or other abnormalities. ERCP can both diagnose the specific cause by visualizing structures and performing biopsies and also treat certain conditions like gallstones through procedures such as sphincterotomy and stent placement. The combination of biochemical and imaging tests aims to determine if the jaundice has an obstructive etiology, identify suspected causes like cancer or gallstones, and assess if the patient is a surgical candidate.
- Anorectal malformations (ARMs) range from minor defects to complex anomalies associated with other issues. They occur in approximately 1 in 5,000 births.
- Evaluation of newborns with ARMs involves examining the anus, genitals, and spine. Imaging studies like ultrasound, MRI and contrast enemas are used to characterize the anatomy and identify any associated anomalies in other organ systems.
- Treatment depends on the specific type of ARM, but may involve procedures like colostomy to allow the distal anatomy to develop before definitive repair. The long-term goals are to establish bowel and urinary continence.
This document contains summaries of various medical cases involving different conditions:
1) Burns on legs presenting complications of wound contractures, scarring, infection, shock, and renal failure.
2) Breast cancer case describing T staging of TNM and clinical types including phylloides tumor, invasive ductal carcinoma, ductal carcinoma in situ, and medullary carcinoma.
3) Thyroid lump involving a multinodular goiter case discussing workup before surgery.
This document discusses breast lumps and the evaluation process. It covers the anatomy of the breast, history taking, clinical examination techniques, and the "triple assessment" process of ultrasound, mammography, and biopsy to establish a diagnosis. The anatomy section describes the structure of the breast including lobes, ducts, and lymphatic drainage. The examination section provides details on inspecting and palpating the breasts and lymph nodes. The triple assessment discusses the use of imaging like ultrasound and mammography as well as biopsy techniques to diagnose breast lumps.
This document discusses abdominal wall defects, specifically omphalocele and gastroschisis. Omphalocele is a birth defect where abdominal organs protrude out of the belly button, which is covered by a sac-like membrane. Gastroschisis is where the intestines protrude out of the abdominal wall to the right of the umbilical cord without a protective sac. Prenatal ultrasound can diagnose these conditions. Treatment for omphalocele may involve conservative management with a sac or surgical closure, while gastroschisis typically requires primary closure. Long-term outcomes depend on the severity of the defect and presence of other anomalies, with generally good prognosis if no other issues are present.
1. Obstructive jaundice results from obstruction of bile flow from the liver to the duodenum, causing bilirubin levels to rise above 2.5mg/dL and resulting in jaundice.
2. The top 3 causes of obstructive jaundice are choledocholithiasis, strictures, and pancreatic cancer.
3. Evaluation involves clinical examination, blood tests of liver function and markers, ultrasound of the bile ducts, and CT or ERCP to visualize the biliary tree and determine the level and cause of obstruction.
This document provides an overview of duodenal atresia, including its definition, epidemiology, etiology, clinical features, diagnosis, management, complications, and differential diagnosis. Duodenal atresia is a congenital absence or closure of part of the duodenum due to defective fusion during development. It commonly presents after birth with vomiting, jaundice, and abdominal distension. Diagnosis is typically made through imaging findings like the "double bubble" sign on x-ray. Surgical management involves bypassing the blocked portion of duodenum through procedures like duodenoduodenostomy. Complications can include anastomotic issues or problems from associated anomalies.
1. A 60-year-old male presented with yellowish discoloration of the eye, itching all over the body, pale stools, loss of appetite, and weight loss.
2. Obstructive jaundice and periampullary carcinoma were suspected given his age, painless progressive jaundice, pruritis, pale stools, and weight loss.
3. Key clinical features of obstructive jaundice include jaundice, intense pruritis, pale stools, loss of appetite and weight in patients typically aged 50-70 years.
This document discusses the differential diagnosis of neck swellings. It begins by defining a neck mass and differential diagnosis. It then describes the various structures that can cause swellings in the head and neck region, including lymph nodes, salivary glands, and muscles. The document outlines the approach to examining a neck mass, including inspecting for location, size, and color, and palpating for tenderness, size, and mobility. Radiographic investigations like MRI, CT, and ultrasound are discussed. Biopsy methods like fine needle aspiration are also summarized.
Choledochal cyst is a rare congenital dilatation of the bile duct that occurs in 1 in 100,000 people. It is more common in Asian populations and women. The pathogenesis is typically due to an anomalous pancreaticobiliary junction, where the pancreatic and biliary ducts fuse before entering the duodenum. This allows pancreatic secretions to reflux into the bile duct and cause inflammation and cystic degeneration. Choledochal cysts are classified into 5 types based on their location and extent. Patients typically present with jaundice, right upper quadrant pain, or a palpable mass. Investigations include ultrasound, CT, MRCP and ERCP to establish the diagnosis and classification. Complications include
Carcinoid tumors are slow-growing neuroendocrine tumors that commonly arise in the gastrointestinal tract and lungs. The document discusses carcinoid tumors in depth, including their definition, sites of origin, histology, staging, clinical features, diagnostic testing, and management approaches. Treatment involves surgical resection when possible, with additional therapies for advanced or metastatic disease aimed at controlling hormone secretion and tumor growth.
1. The document discusses various potential causes of a mass in the right iliac fossa, including appendicitis, appendicular abscess, carcinoid tumors of the appendix, mucoceles, adenocarcinoma, tuberculosis, Crohn's disease, carcinoma of the caecum, actinomycosis, amoebiasis, mesenteric cysts, intussusception, iliopsoas abscess, retroperitoneal tumors, aneurysms, and more rare causes.
2. Diagnostic tools mentioned include ultrasound, CT, colonoscopy, and biopsy. Treatment depends on the underlying cause but may include antibiotics, surgery, chemotherapy, and ATT.
3
This document discusses the management and treatment of hydrocele. It outlines the necessary investigations which may include blood tests, urine tests, and chest x-rays. Ultrasound is helpful for determining testis position and abnormalities. Fluid aspiration can indicate different conditions. Surgical procedures like lord's plication and Jaboulay's operation are described for fixing different types of hydroceles. Post-operative care and potential complications are also covered. The document provides an overview of evaluating and treating hydroceles.
focal nodular hyprplasia FNH case PRESENTATIONChinmay Mehta
A 40-year-old woman presented with abdominal pain and hypotension. Imaging found a large liver lesion and hemorrhagic fluid in the peritoneum. Differentials included ruptured ectopic pregnancy or hepatic tumor. CT showed an encapsulated heterogeneous liver lesion involving the left lobe with normal vasculature. Follow up CT showed resolution of ascites without change in the liver lesion. MRI was suggestive of focal nodular hyperplasia (FNH) based on enhancement patterns. Treatment options for FNH include observation, ablation, embolization, or excision.
Gastric cancer seminar presentation covered the following topics in 3 sentences or less:
The presentation discussed the anatomy, blood supply, lymphatic drainage and histology of the stomach. Risk factors, clinical presentation, diagnostic tools and staging of gastric cancer were explained. Surgical treatment options including endoscopic resection, gastrectomy and lymph node dissection were summarized along with reconstruction methods.
This document discusses three cases of acute abdominal conditions seen by a surgical gastroenterologist.
Case 1 involves a 55-year-old male with left lower quadrant pain and fever diagnosed with diverticulitis based on CT findings. The patient underwent left hemicolectomy with sigmoid resection and diverting loop ileostomy.
Case 2 describes a 53-year-old male with abdominal pain found to have an acute SMA thrombosis on CT angiography. The patient was treated conservatively with heparin and antibiotics.
Case 3 involves a 65-year-old cirrhotic male with SMV thrombosis found on CECT. The patient deteriorated clinically despite conservative management and required small bowel resection during
1) The 80-year-old male patient presented with 5 months of abdominal pain, weight loss, and recent vomiting. Imaging showed a pancreatic mass encasing the splenic artery and gastric outlet obstruction.
2) Laboratory tests showed elevated tumor markers consistent with a probable malignant pancreatic mass.
3) The pre-op diagnosis is a pancreatic mass likely malignant causing gastric outlet obstruction. The proposed surgical plan is a palliative double bypass surgery including gastrojejunostomy, jejunostomy, and cholecystojejunostomy.
1. Abdominal trauma is commonly encountered in emergency departments and can be life-threatening. Blunt and penetrating injuries can cause damage to solid organs like the spleen, liver, and pancreas.
2. A thorough primary and secondary survey is essential to identify injuries. Diagnostic tools like FAST ultrasound, CT scans, and laparoscopy help evaluate injuries. Conservative management is appropriate for many mild organ injuries.
3. Splenic injuries require close monitoring or surgery depending on grade. Liver injuries often stop bleeding spontaneously but may require packing or resection. Pancreatic injuries are difficult to diagnose and usually repaired surgically. Proper identification and treatment of abdominal injuries is critical for patient outcomes.
This document discusses obstructive jaundice, including a case study of an 82-year-old male patient presenting with progressive jaundice, itching, weight loss, and other symptoms. It reviews the causes, pathophysiology, investigations, and management of obstructive jaundice. Common causes include gallstones, pancreatic cancer, and cholangiocarcinoma. Investigations may include blood tests, ultrasound, CT, MRCP, and ERCP. Management depends on the underlying cause but may involve surgical procedures like cholecystectomy, Whipple procedure, or stenting to relieve the obstruction.
This document describes a case of obstructive jaundice in an 82-year-old male presenting with progressive jaundice, itching, weight loss, and pale stools. Examination found jaundice, scratch marks, and a palpable gallbladder. Investigations showed elevated bilirubin and alkaline phosphatase consistent with obstructive jaundice. Imaging found a solid mass in the distal common bile duct. The causes, pathophysiology, investigations, and management of obstructive jaundice are then reviewed, focusing on endoscopic or surgical interventions depending on the underlying cause such as gallstones, pancreatic cancer, cholangiocarcinoma. Prognosis depends on factors like type of obstruction and patient
A 40-year-old male presented with abdominal pain and was found to have an epigastric mass. Differential diagnoses included pancreatic cancer, but imaging revealed a pancreatic pseudocyst. Pancreatic pseudocysts develop due to pancreatic duct disruption from acute or chronic pancreatitis. They can be managed conservatively but often require drainage if causing symptoms. The patient underwent cystogastrostomy to drain the pseudocyst.
This document summarizes information about carcinoma of the gallbladder. It discusses that carcinoma of the gallbladder is rare but more common in females. Risk factors include chronic inflammation from gallstones. It spreads early through lymphatics and blood vessels due to the gallbladder's anatomy. Surgical resection is the main treatment but prognosis is poor due to late stage at presentation. Adjuvant chemotherapy may improve outcomes for high-risk patients but targeted therapies have limited effectiveness for this cancer.
A 56-year-old postmenopausal woman presented with urinary frequency and abdominal bloating. Examination revealed a large cystic and firm mass in her pelvis. Transvaginal ultrasound and CT scan confirmed a 4.5x5.0x7.5cm complex right pelvic mass and elevated CA-125 level of 622 U/ml. She underwent exploratory laparotomy involving a hysterectomy, salpingo-oophorectomy, and omentectomy to optimally debulk the tumor, followed by chemotherapy with carboplatin and paclitaxel to further treat and prevent recurrence of ovarian cancer.
A 75-year-old male presented with constipation and abdominal bloating. Diagnostic workup revealed colonic adenocarcinoma. He underwent sigmoidectomy and Hartmann's procedure. Pathology confirmed well-differentiated colonic adenocarcinoma. Risk factors for the patient included age, smoking history, and family history of colon cancer. Treatment guidelines include surgical resection and chemotherapy depending on stage.
A 50-year-old female presented with a 10-day history of pain in the lower right abdomen. Examination revealed an 8x10cm mass in the right iliac fossa. Imaging showed an appendicular mass and abscess. The mass did not resolve with conservative treatment over 15 days. Exploratory laparotomy found a mucinous adenocarcinoma of the appendix that had spread. A right hemicolectomy was performed. Histopathology confirmed a well-differentiated mucin-producing adenocarcinoma with lymph node metastases. Appendiceal adenocarcinoma is a rare and often delayed diagnosis that requires surgical resection.
This document provides information on pancreatic cancer including incidence, risk factors, clinical presentation, staging, investigations, surgery, palliation and controversies in management. Some key points are:
- Pancreatic cancer incidence is highest in American Blacks at 11-13 per 100,000 people and 80% of cases occur in those over age 60.
- Only 20% of pancreatic cancers are operable for cure and the 5-year survival is less than 5% due to late presentation and aggressive biology.
- CT scan is the gold standard for staging to assess operability. Surgical resection through pancreaticoduodenectomy or distal pancreatectomy offers the only chance for cure but is only possible in 20-30% of
The document discusses liver cancer, including its causes, pathophysiology, signs and symptoms, diagnosis, treatment, complications, nursing diagnoses, and nursing interventions. Specifically, it notes that liver cancer is often caused by cirrhosis from alcohol or hepatitis B/C infections. It damages liver cells, causing uncontrolled growth. Symptoms include abdominal pain, bruising, jaundice. Diagnosis involves scans, biopsy, blood tests. Surgery or transplant can treat early tumors, while chemotherapy and radiation may help later cases. Nursing focuses on pain management, diet, skin care, education, and monitoring for complications like bleeding or infection.
The document discusses liver cancer, including its causes, signs and symptoms, diagnosis, treatment, complications, nursing diagnoses, and nursing interventions. Specifically, it notes that liver cancer is often caused by cirrhosis from alcohol or hepatitis B/C infections. Signs include abdominal pain and jaundice. Diagnosis involves scans, ultrasound, biopsy and liver tests. Surgery or transplant can treat early tumors, while chemotherapy and radiation may help later cases. Nursing focuses on pain management, diet, skin care, respiratory monitoring and emotional support.
This document provides information about a case presentation of a 19-year-old male student named Ahmad who presented with rectal bleeding and anal pain and swelling. On examination, he was found to have hemorrhoids and signs of anemia. Sigmoidoscopy revealed hemorrhoids that were banded. He received a blood transfusion and IV fluids and was diagnosed with anemia secondary to bleeding hemorrhoids. The document also provides background information on hemorrhoids, appendicitis, colorectal polyps, and familial adenomatous polyposis.
Colon cancer can develop due to chromosomal instability or microsatellite instability. Presentation may be asymptomatic, or include changes in bowel habits, blood in stool, weight loss, or abdominal masses. Diagnosis involves tests such as colonoscopy, biopsy, and imaging. Treatment depends on stage and includes surgery to remove the cancerous section of colon as well as nearby lymph nodes, with the possibility of additional chemotherapy or radiation. Recurrence is common within the first few years and is monitored through cancer antigen testing, imaging and colonoscopy surveillance.
This document discusses imaging in abdominal trauma. It begins by outlining the mechanisms and types of abdominal injuries from blunt and penetrating trauma. It then describes the FAST (Focused Assessment with Sonography for Trauma) exam and its role in the initial assessment of hemodynamically unstable patients. For stable patients, CT is typically used to further evaluate injuries suggested on clinical exam or FAST. The document outlines key CT findings for various intra-abdominal injuries and hemorrhage.
This document summarizes the medical history and examination of a 56-year-old female patient presenting with an abdominopelvic mass. Key details include:
- The patient has a history of 5 pregnancies and 4 deliveries, with her last delivery in 2001.
- Ultrasound showed a myoma uteri and right ovarian mass with benign features measuring 16.8 x 13.7 cm.
- On examination, the patient had a globularly enlarged abdomen with a cystic mass measuring 21 x 26 cm that was movable and non-tender.
This case report describes a 40-year-old female who presented with abdominal pain and nausea. Imaging showed left ovarian cysts and right adnexal cysts. She underwent a cystectomy of the left ovary and unilateral salpingo-oophorectomy of the right ovary. Pathology found a mature cystic teratoma in the left ovary measuring 9x7x5 cm containing sebaceous material, hair structures, and 3 tooth-like structures. The right ovary contained a 7x7.5x3 cm paratubal cyst and hematosalpinx. The final diagnosis was mature cystic teratoma bilaterally and hematosalpinx and paratub
Adhesions are fibrous bands that form as a result of injury to the peritoneum during surgery and can constrict organs, potentially leading to bowel obstruction. While most adhesions are asymptomatic, they can cause problems from the second week after surgery to years later. Adhesiolysis is surgery to remove or divide adhesions in order to restore normal anatomy and function and relieve painful symptoms.
This document discusses urinary incontinence and the approach to patients with this condition. It describes the somatic, sympathetic, and parasympathetic nerves involved in bladder control and micturition. The main types of incontinence are described as stress, urge, overflow, and mixed. Risk factors include increasing age, childbirth, and medical comorbidities. The evaluation of patients with urinary incontinence involves reviewing voiding patterns, medications, functional status, and performing a digital rectal exam and bladder palpation.
This document discusses reconstructive surgery for facial fractures involving the lower third of the face. It covers key considerations and techniques for treating fractures of the dentate mandible, edentulous mandible, and panfacial fractures. Important priorities include reestablishing proper occlusion and load-bearing ability. Techniques discussed include miniplate fixation, reconstruction plating, and mandibulomaxillary fixation. Complications addressed are malocclusion, malunion, non-union, soft tissue problems, and nerve injuries.
Multiple endocrine neoplasia (MEN) is characterized by tumors involving two or more endocrine glands. There are four main types of MEN: MEN type 1 is associated with tumors of the parathyroid, pancreas, and pituitary glands. MEN type 2 is associated with medullary thyroid carcinoma, pheochromocytomas, and parathyroid tumors. MEN type 3, also called MEN 2B, involves the same tumors as MEN 2A but also includes other features. MEN type 4 involves tumors associated with MEN 1 and CDNK1B gene mutations. The tumors associated with each MEN type are inherited in an autosomal dominant pattern and can be diagnosed clinically
Acute kidney injury (AKI) can lead to several complications related to the kidney's roles in homeostasis. Complications range from mild, asymptomatic issues to more severe problems involving fluid balance, electrolytes, acid-base balance, and organ function. Management of AKI focuses on treating the underlying cause, supportive care including fluid management and dialysis, and preventing or managing complications. Outcomes depend on the severity and cause of AKI, with prerenal and postrenal causes generally having a better prognosis than intrinsic kidney injury.
This document provides an overview of gastroesophageal reflux disease (GERD). It defines GERD as symptoms or complications resulting from reflux of gastric contents into the esophagus. Approximately 15% of US adults are affected by GERD based on reports of chronic heartburn. The pathophysiology involves transient lower esophageal sphincter relaxations and impaired esophageal clearance allowing gastric acid and other contents to reflux into the esophagus and cause inflammation. Clinical manifestations include heartburn, regurgitation, dysphagia, and chest discomfort. Diagnostics include endoscopy, pH monitoring, and manometry. Differential diagnoses require excluding other causes of esophageal symptoms.
1. Nystagmus is defined as involuntary, rhythmic oscillations of the eyes and can be caused by disturbances in the visual, vestibular, or brainstem pathways.
2. There are three main types of nystagmus - physiological, sensory deprivation, and motor imbalance. Physiological nystagmus occurs normally while sensory deprivation nystagmus is due to reduced visual input and motor imbalance nystagmus arises from problems with eye movement control.
3. Specific forms of nystagmus include optokinetic nystagmus from moving visual stimuli, congenital pendular nystagmus associated with visual impairments like cataracts, and downbeat nystagmus linked to
This document discusses medication administration through different routes. It begins by outlining the 10 rights of medication administration and various drug preparations. It then describes several routes of administration including oral, rectal, parenteral, topical, inhalation, ophthalmic, and otic. Specific procedures for intramuscular and intradermal injections are also provided, with steps for administering the injections and locating appropriate injection sites.
This document outlines diseases of the oral cavity and upper airways. It begins with an outline of topics including diseases of the teeth/supporting structures, inflammatory/reactive lesions of the oral cavity, infections, oral manifestations of systemic diseases, precancerous and cancerous lesions, and odontogenic cysts and tumors. It then provides more detailed descriptions of several common conditions including dental caries, gingivitis, periodontitis, aphthous ulcers, irritation fibroma, pyogenic granuloma, peripheral ossifying fibroma, herpes simplex virus, oral candidiasis, hairy leukoplakia, leukoplakia/erythroplakia, squamous cell carcinoma
This document discusses cellular reactions and pathologies in the central nervous system. It begins by outlining the typical reactions of neurons, astrocytes, microglia, and other glial cells to injury. It then describes various inclusion bodies, degenerative changes, and proliferative reactions that may occur. The rest of the document covers topics like cerebral edema, hydrocephalus, herniation, malformations and developmental disorders of the brain. It includes detailed descriptions and diagrams of various neural tube defects, forebrain anomalies, and other congenital central nervous system abnormalities.
This document summarizes Tarui disease, a rare genetic disorder of glycolysis. It is caused by a deficiency of the phosphofructokinase enzyme, which catalyzes a key step in glycolysis. This leads to symptoms like muscle pain and fatigue with exercise that resolves with rest. Tarui disease has several subtypes depending on age of onset, ranging from mild to severe presentations that can be fatal. Diagnosis involves specialized testing like muscle biopsies and genetic analysis. Management focuses on avoiding strenuous exercise and monitoring for complications.
This document provides information on seronegative spondyloarthropathies (SpA), including ankylosing spondylitis (AS). Key points:
- SpA involve ligamentous attachments rather than the synovium and commonly affect the sacroiliac joints. They are seronegative for rheumatoid factor.
- AS is a chronic inflammatory disorder primarily involving the sacroiliac joints and axial skeleton. It has associations with HLA-B27 and may involve extra-articular manifestations.
- Diagnosis of AS combines criteria of inflammatory back pain, enthesitis or arthritis on physical exam with radiographic findings like sacroiliitis and syndesmophyte formation seen
This document provides information about Baymax, who introduces himself as a personal healthcare provider. It then provides details on performing a physical exam, including preparing for the exam, establishing rapport with the patient, ensuring privacy and comfort, and explaining findings. Common symptoms that may warrant examination are listed. The physical exam components covered include vital signs, skin, head, eyes, ears, nose, mouth, neck, lungs, heart, abdomen, back, extremities, neurologic exam and mental status exam.
This document discusses various types of neuropathies that can be associated with cancer. It describes local effects of tumor infiltration or compression of nerves. It also discusses neuropathies caused by complications of cancer therapy like chemotherapy or radiation. Additionally, it outlines paraneoplastic neuropathies which occur due to substances produced by the tumor and can precede cancer diagnosis. Specific paraneoplastic neuropathies mentioned include sensorimotor neuropathy often linked to small cell lung cancer and neuropathies associated with monoclonal gammopathies where paraproteins secreted by cancerous B cells can damage nerves.
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8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptxHolistified Wellness
We’re talking about Vedic Meditation, a form of meditation that has been around for at least 5,000 years. Back then, the people who lived in the Indus Valley, now known as India and Pakistan, practised meditation as a fundamental part of daily life. This knowledge that has given us yoga and Ayurveda, was known as Veda, hence the name Vedic. And though there are some written records, the practice has been passed down verbally from generation to generation.
Cell Therapy Expansion and Challenges in Autoimmune DiseaseHealth Advances
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
Osteoporosis - Definition , Evaluation and Management .pdfJim Jacob Roy
Osteoporosis is an increasing cause of morbidity among the elderly.
In this document , a brief outline of osteoporosis is given , including the risk factors of osteoporosis fractures , the indications for testing bone mineral density and the management of osteoporosis
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These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
share - Lions, tigers, AI and health misinformation, oh my!.pptxTina Purnat
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• Evidence-based strategies to address health misinformation effectively
• Building trust with communities online and offline
• Equipping health professionals to address questions, concerns and health misinformation
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Histololgy of Female Reproductive System.pptxAyeshaZaid1
Dive into an in-depth exploration of the histological structure of female reproductive system with this comprehensive lecture. Presented by Dr. Ayesha Irfan, Assistant Professor of Anatomy, this presentation covers the Gross anatomy and functional histology of the female reproductive organs. Ideal for students, educators, and anyone interested in medical science, this lecture provides clear explanations, detailed diagrams, and valuable insights into female reproductive system. Enhance your knowledge and understanding of this essential aspect of human biology.
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1. “A BULK IN THE TUNNEL”
Ron Christian Y. Calalang
Deepak Singh Yadav
Clinical Clerks
2. GENERAL DATA
• O.N.
• 75/F
• Roman Catholic
• 5/29/1944
• Minalabac, Camarines Sur
• Chief Complaint: Vomiting
• Informant: Daughter and Patient Herself
• Reliability: 90%
3. HPI
3 mos PTA
-left lower quadrant pain,
colicky, mild to moderate in
intensity accompanied with
bloating.
-No associated fever or
vomiting. No consult done.
No medications taken.
Interim
-same pain felt
intermittently, with noted
decrease in caliber of stools
and progressive episodes of
constipation.
- No consult done. No meds
taken.
1 day PTA
-pain increased in intensity radiating to
the umbilical and right quadrant
(+) pelvic pain and urge to defecate
but cannot pass stool
(+) 4 bouts of coffee-ground vomitus:
about ¼- ½ cup each bout.
Persistence of symptoms- Consult
4. PAST MEDICAL HISTORY
• (+) Hypertension, ~10 years, on Losartan, fairly
compliant to meds
• (-) Diabetes Mellitus
• (-) Cardiac disease
• (-) Previous surgery
• (-) Allergies
5. OBSTETRIC HISTORY
• G9 P9 (9009) – all delivered via normal
spontaneous deliveries
• Menopause: 48 years old
7. PERSONAL SOCIAL HISTORY
• (-) tobacco use
• (-) alcoholic drinker
• Patient’s usual diet includes fish and
vegetables. Denies frequent intake of
processed foods.
9. PHYSICAL EXAMINATION
• General: conscious, coherent, stretcher-borne, not in cardiorespiratory
distress
• Vital Signs: BP: 160/90 HR: 84 RR: 19 T: 36.7 C O2 Sat: 99%
• HEENT: pink palpebral conjunctivae, no lesions, no neck vein engorgement,
no neck mass, no cervical lymphadenopathy
• Chest: symmetrical chest expansion, clear breath sounds
• Heart: adynamic precordium, normal rate regular rhythm, no murmurs
• Abdomen: no surgical scars, flat, hyperactive bowel sounds, flabby,
distended, with abdominal tenderness on both lower quadrants,
palpable mass, left lower quadrant
• Extremities: no edema, no pallor, with full equal pulses, capillary refill time <
2 secs
• DRE: no external lesions, good sphincter tone, (+) mass, hard, 7-8 cm from
the anal verge, no fecal material, no blood on examining finger
10. SALIENT FEATURES
• 75 years old/ female
• Left lower quadrant pain
• Decrease in caliber of stools
• Weight loss
• Insidious onset (3 months PTA)
• Difficulty in defecation
• Vomiting
• Palpable mass, LLQ and 7-8 cm from anal verge
11. DIFFERENTIAL DIAGNOSES
Differential Dx Rule In Rule Out
Colorectal mass Obstructive symptoms
Age
Insidious onset
Weight loss
Palpable mass, 7-8 cm
from anal verge
Volvulus Palpable mass LLQ
Obstructive symptoms
Age
(+) Weight loss
(+) insidious onset
Palpable rectal mass
15. LABORATORY/ ANCILLARY TESTS
• CBC- to detect anemia; can reflect infection
• Blood typing- in anticipation for possible blood
transfusion
• Na, K, BUN, Creatinine- baseline; detect electrolyte
imbalance or elevated creatinine or BUN; prep for
contrast studies
• Protime- to screen for bleeding problem
• CEA- baseline level for post treatment surveillance
• Urinalysis-to detect for infection, blood in the urine, etc
16. LABORATORY TESTS
• CBC
• Blood typing
• Na, K, BUN, Creatinine
• Protime
• Urinalysis
Sodium 135.74 L
Potassium 3.88
BUN 5.54
Creatinine 39.90 L
Protime 11 secsBT O+
Color: Dark yellow Blood (-) WBC 7.30/ul
Character: Clear Bilirubin (-) RBC 28.50/ul ↑
pH 5.5 Urobilinogen Normal
Specific gravity1.027 Ketone (-), CHON (-),
Glucose (-)
Bacteria 173.30
13.3
3
120
0.35
4
85.8
339
CEA 73.9
17. IMAGING
• Chest X-ray- detect for pneumonia or other pulmonary
problems and cardiac enlargement,
• Abdominal X-ray, upright and supine- detect free intra-
abdominal air, bowel-gas patterns
• WAB CT-Scan with Triple contrast- provide more
detailed information on abdominal structures
specially those that are inconclusive in standard x-
rays
• However, a standard CT scan is relatively insensitive for the detection of intraluminal lesions
specially in assessing bulky rectal tumors and perirectal adenopathy.
18. • Chest X-ray
• Abdominal X-ray,
upright and supine
• WAB CT-Scan with
Triple contrast
20. ANATOMY OF THE RECTUM
• 5 in (12 cm) in length
• Begins anterior to the third
segment of the sacrum or at
the rectosigmoid junction
• Ends at the level of the
lower quarter of the vagina,
(or at the apex of the
prostate) where it leads into
the anal canal
21. ANATOMY OF THE RECTUM
• Rectosigmoid
Junction- narrowest
portion of LI where
the 3 taenia coli fuse
together
22. ANATOMY OF THE RECTUM
• Curved antero-
posteriorly and laterally
• Antero-posterior
flexures
• Sacral- ff the curve of
the coccyx
• Perineal-terminal part
of rectum
23. •Has NO: taenia coli,
omental appendices,
haustrations,
•Has 3 transverse folds
(valves of Houston)
•Rectal ampulla- largest
portion of rectum storing
the feces
35. PATIENT’S SUMMARY
• Patient came in with features of bowel obstruction, and was admitted with
consent at the ward.
• Diagnostics were facilitated.
• Hooked to IVF. NGT and IFC inserted. Replaced NGT loses with IVF volume
per volume.
• Initial plan: Explore Laparotomy
• Seen by IMCP, Anesthesia
• Referred to and Co-Managed by IM-Onco and IM-Gastro
• Initially for EGD, Colonoscopy but was deferred due to abdominal
distension, generalized abdominal tenderness.
• Planned for Ex-Lap, rectosigmoidectomy Hartmann’s procedure.
36. PATIENT’S SUMMARY
• Intra-op findings:
• Closed-loop obstruction at rectosigmoid area with mass involving the
left ovary and ileum 80 cm from the ileocecal valve with noted swelling
near right reproductive tube
• Biopsy was then obtained.
• Ileostomy done over resected area of the ileum. Jackson-Pratt drain
placement done.
• JP drain monitoring done. Progressive diet. Colostomy care. Daily wound
care. Chest physiotherapy.
• Discharged stable with no signs of surgical complication.
• To follow up at Onco Center, Cardio OPD and Surgery OPD.
37. • Dx: Partial Intestinal Obstruction secondary to
Rectosigmoid Cancer stage IV (T4bN2bM1)
38.
39. COLORECTAL CANCER
• Colorectal carcinoma is the most common
malignancy of the gastrointestinal tract.
• 3rd most common cancer and the 3rd leading cause
of cancer deaths in the Philippines
• Risk factors: aging, hereditary factors, dietary
factors, consumption of processed meat,
Inflammatory Bowel disease, Obesity and sedentary
lifestyle, smoking, diabetes mellitus
40.
41.
42. RECTAL CA
• anatomy of the pelvis and proximity of other structures (ureters,
bladder, prostate, vagina, iliac vessels, and sacrum) make
resection more challenging and often require a different approach
than for colonic adenocarcinoma.
• it is more difficult to achieve negative radial margins in rectal
cancers that extend through the bowel wall because of the
anatomic limitations of the pelvis.
• local recurrence is higher
• relative paucity of small bowel and other radiation- sensitive
structures in the pelvis makes it easier to treat rectal tumors with
radiation.
43. • Survival extremely limited in stage IV rectal carcinoma.
• highly selected patients with isolated, resectable metastases may
benefit from resection (metastasectomy).
• Liver- most common site of metastasis (15%); 2nd– lungs; others–
retroperitoneum, ovary
• Of these, 20% are potentially resectable for cure.--survival
improved (20% –40% 5-year survival)
• Hepatic resection of synchronous metastases from colorectal
carcinoma may be performed as a combined procedure or in two
stages.
• The remainder of patients with stage IV disease cannot be cured
surgically, and therefore, the focus of treatment should be
palliation.
• diverting stoma or bypass procedure may be appropriate in
patients with stage IV disease who develop obstruction.
44. • Stage IV: Distant Metastasis (Tany, Nany, M1).
• Isolated hepatic and/or pulmonary metastases are rare, but
present may be resected for cure in selected patients.
• Some patients will require palliative procedures.
• Radical resection may be required to control pain, bleeding, or
tenesmus,
• Local therapy using cautery, endocavitary radiation, or laser
ablation may be adequate to control
• bleeding or prevent obstruction.
• proximal diverting colostomy may be required to alleviate
obstruction
• It is critical that the morbidity of any procedure be realistically
weighed against potential benefit in these patients with limited
45.
46.
47.
48.
49. Sources:
• Schwartz’s Principles of Surgery, 10th Edition
• NCCN Clinical Practice Guidelines in Oncology, 2017
• Ellis’ Applied Anatomy for Students and Junior Doctors, 11th Edition
• Moore’s Clinically Oriented Anatomy, 7th Edition
• Gray’s Anatomy for Students, 2nd Edition
• Netter’s Atlas of Human Anatomy, 6th Edition
• Google Images
THANK YOU
Editor's Notes
CEA-still the most widely used tumor marker for gastrointestinal cancer,
originally thought to be a specific marker for colorectal cancer but turned out to be a nonspecific marker on further studies.
-- can be elevated in breast, lung, and liver cancers
--used to follow patients during therapy and to detect recurrence after successful surgery.
marker for monitoring colorectal cancer
The association between highly elevated serum tumor marker concentration and
metastases and poor prognosis was also discovered through CEA studies.
Elevated CEA levels before resection of colon cancer may suggest a worse prognosis.
However, a low positive predictive value for diagnosis in asymptomatic patients limits its widespread use in screening.
Normal CEA 3 ng/mL
Plain X-rays of the abdomen are useful for detecting free intra-abdominal air, bowel gas patterns suggestive of
small or large bowel obstruction
Triple contrast- oral, IV and rectal contrast medium
To find pathology by enhancing the contrast between a lesion and normal tissue
detection of extraluminal disease, such as intra-abdominal abscesses and pericolic inflammation,
sensitivity in detection of hepatic metastases
However, a standard CT scan is relatively insensitive for the detection of intraluminal lesions specially in
assessing bulky rectal tumors and perirectal adenopathy.
Extravasation of oral or rectal contrast- perforation
Nonspecific findings such as bowel wall thickening or mesenteric stranding may suggest inflammatory bowel disease, enteritis/colitis,
or ischemia.
A chest xray of a 75 year old female taken on PA view.
With good visualization (entire thoracic cage)
With good inspiratory effort (> 8 intercostal spaces, 6-8 ant. Ribs, 9-11 post ribs)
Wth good exposure
No obliquity
(+) poorly defined densities on the upper lobes, more on the right- consider PTB(+) atheromatous aorta
Normal heart size.
No blunting of costophrenic angle
With thoracic dextroscoliosis.
Understanding thorough anatomy is key in surgical mgt
rectum is straight in lower mammals (hence its name) but
rectum is straight in lower mammals (hence its name) but
rectum is straight in lower mammals (hence its name) but
Valves of Houston:
Thought to serve as support to fecal mass to avoid distention of rectal ampulla
Rectal ampulla-lies immediately above the pelvic diaphragm and stores the feces.
Has a peritoneal covering on its anterior, right, and left sides for the proximal third;
only on its front for the middle third; and
no covering for the distal third.
Receives blood from the superior, middle, and inferior rectal arteries and the middle sacral artery.
(The superior rectal artery pierces the muscular wall and courses in the submucosal layer and anastomoses with branches of the inferior rectal artery. The middle rectal artery supplies the posterior part of the rectum.)
Posteriorly lie sacrum and coccyx and the middle sacral artery, which are separated from it by extraperitoneal connective tissue containing the rectal vessels and lymphatics. The lower sacral nerves, emerging from the anterior sacral foramina, may be involved by growth spreading posteriorly from the rectum, resulting in severe sciatic pain.
A layer of fascia (Denonvilliers) separates the rectum from the anterior structures and forms the plane of dissection which must be sought after in excision of the rectum.
Laterally, the rectum is supported by the levator ani.
pudendal nerve is formed from the sacral plexus – a network of nerve fibres located on the posterior pelvic wall. ... It then crosses the sacrospinous ligament (close to its insertion to the ischial spine), and then re-enters the pelvis through the lesser sciatic foramen.
Has venous blood that returns to the portal venous system via the superior rectal vein and to the caval (systemic) system via the middle and inferior rectal veins. (The middle rectal vein drains primarily the muscular layer of the lower part of the rectum and upper part of the anal canal.)
Anastomoses occur between SUPERIOR RECAL VEIN (PORTAL) and SYSTEMIC VEINS– PORTOSYSTEMIC Shunt--- increase in portal pressure may lead to rectal varices
Abdominal xrays of the same pt. taken on AP supine and standing views.
With good visualization, exposure, no obliquity.
With notable gas-dilated bowels with multiple air fluid levels- indication bowel obstruction
In the upright projection, there is lack of noticeable gas in the lower abdomen.
No sign of intraperitoneal free air
Had the patient come in at a different time or condition, for example, without obstructive symptoms,
*pT1 tumours are those that invade into the subepithelial connective tissue or lamina propria
The amount of serosanguineous fluid should decrease each day and the color of the fluid will turn light pink or light yellow. Your surgeon will usually remove the bulb when drainage is below 25 ml per day for two days in a row. On average, JP drains can continue to drain for 1 to 5 weeks.
Complications of ileostomy:
Stoma necrosis = early postoperative period; usually caused by skeletonizing the distal small bowel and/or creating an overly tight fascial defect.
Limited mucosal necrosis above the fascia may be treated expectantly, but necrosis below the level of the fascia requires surgical revision.
Stoma retraction= may occur early or late and may be exacerbated by obesity. Local revision may
be necessary.
dehydration with fluid
and electrolyte abnormalities= creation of an ileostomy bypasses the fluidabsorbing
capability of the colon
Ideally, ileostomy output should be maintained at less than 1500 mL/d to avoid this problem.
Bulk agents and opioids (Lomotil, Imodium, tincture of opium) are useful. The somatostatin analogue,
octreotide, has been used with varying success in this setting.
Skin irritation can also occur, especially if the stoma appliance fits poorly. Skin-protecting agents and custom pouches can help to solve this problem.
Obstruction may occur intra-abdominally or at the site where the stoma exits the fascia. Parastomal hernia
is less common after an ileostomy than after a colostomy but can cause poor appliance fitting, pain, obstruction, or strangulation.
In general, symptomatic parastomal hernias should be repaired.
A variety of techniques to repair these hernias have been described, including local repair (either with or without mesh), laparoscopic repair, and stoma resiting.
Prolapse is a rare, late
complication and is often associated with a parastomal hernia.
P53- tumor suppressor
K-ras= signals cell growth and multiplication
Surgery is mainstay of treatment
Pre-operative radiotherapy or chemoradiation for rectal CA
Post-operative chemoTx and radioTx for stage II rectal CA
Post-operative chemoTx for stage III colon CA
Therapeutic decisions, therefore, are based on the location and depth of the tumor and its relationship
to other structures in the pelvis.
5-FU acts in several ways, but principally as a thymidylate synthase (TS) inhibitor. Interrupting the action of this enzyme blocks synthe
Leucovorin-used in combination with 5-fluorouracil to treat colorectal cancer, may be used to treat folate deficiency that results in anemiasis of the pyrimidine thymidine, which is a nucleoside required for DNA replication.