Quasi-experimental research designs involve manipulating an independent variable to observe its effects on a dependent variable, unlike true experiments which require random assignment and control groups. Quasi-experiments lack one of these characteristics. There are two main types: non-randomized control group designs where experimental and control groups are not randomly assigned, and time series designs which measure the effects of a treatment over multiple time periods with an individual or small group. Quasi-experiments are more practical than true experiments but less reliable for establishing causation due to lack of control over extraneous variables.