PubMed Essentials
       Feb 22, 2011

   ROBIN FEATHERSTONE,
SLIDES: www.slideshare.net/featherr
Levels of Evidence Pyramid
      Systematic Reviews of                       Less Time
      Randomized Controlled Trials                Less Work
                                                  Less Evidence

      Critically Appraised Topics


                                      FILTERED



Randomized Controlled Trials

Cohort Studies & Case
Reports
                                     UNFILTERED               More Time
Case Controlled                                               More Work
Studies                                                       More Evidence
Needs Assessment
•   How often do you use PubMed?
•   Why do you use it?
•   What are you looking for?
•   What (if any) problems have you encountered?
Objectives
After this class, you’ll be able to do the following
                       in PubMed:

1.   Execute a simple search
2.   Locate full text
3.   Use subject headings
4.   Use Single Citation Matcher
5.   Apply limits
6.   Save searches
Simple Searches
What are you looking for?
                Well… I’m working on this
                research team and we’re
                investigating the use of
                magnesium sulfate as a
                possible mechanism for
                improving neurological
                outcomes after acute
Identify your   traumatic brain injury in
key concepts:   young adults. We’d like to
                know what studies have
                been conducted.
Find the key concepts…
1. What are risk factors for myocardial infarction as a
   postoperative complication after infrarenal
                                     infrarenal
   abdominal aortic aneurysm repair?
                               repair

2. Are childhood cancer survivors more likely to have
   gastrointestinal complications later in life?

3. What impact does population density have on
                      population density
   incidence of Type II Diabetes
                        Diabetes?
Combining search terms

• Use OR to find MORE
  results on the same
  concept
                         ex. heart attack OR myocardial infarction




• Use AND to find LESS
  results using two or
  more concepts
                          ex. heart attack AND diet therapy
AND or OR?

A. myocardial infarction   B. infrarenal abdominal
                           aortic aneurysm repair
AND or OR?

A. myocardial infarction         B. infrarenal abdominal
                                 aortic aneurysm repair




                           AND
Exercise: Search PubMed using these
    terms with either AND or OR
1. myocardial infarction ? heart attack
2. diet therapy ? caloric restriction
3. childhood cancer ? gastrointestinal
   complications
4. population density ? Type II Diabetes
Locating Full Text
Where to go from here?
3 Ways to Find Full Text
1. Select the publisher link in PubMed




2. Search the journal name in the McGill
   Library catalogue
3 Ways to Find Full Text, cont…
3. Request it from us!
   http://muhclibraries.mcgill.ca/
Exercise
• Conduct a quick search in PubMed on
  complications following laparoscopic robotic
  hysterectomy

• Locate two full text articles
Using Subject Headings
Medical Subject Headings (MeSH)
• MeSH Terms are added to references to
  describe the subject of these articles

• Search with MeSH Terms to increase the
  relevancy of your results
Search Using MeSH
•   Identify key concepts
•   Search MeSH database to find MeSH Terms
•   Send terms to the Search Box with AND or OR
•   Search PubMed
Demo


Using MeSH, find articles about cardiac
catheterization methods for patients awaiting a
heart transplant
Exercise & 10 min Break
Using MeSH, find articles on the following:

1. NSAIDS for rheumatoid arthritis during
   pregnancy

2. Metformin for breast cancer prevention

Bonus – immunosuppression for HIV infected
   patients following kidney transplantation
Objectives
After this class, you’ll be able to do the following
                       in PubMed:

1.   Execute a simple search
2.   Locate full text
3.   Use subject headings
4.   Use Single Citation Matcher
5.   Apply Limits
6.   Save searches
Scenario
You’re looking for:

• A particular article
• Articles written by a specific author
• Articles published in a particular journal
Demo
• Find an articles published in 2011 in the
  journal Diagnostic Cytopathology about
  fibroadenoma of the breast
Exercise
•   Using Single Citation Matcher find:

1. Articles written by Daniel M. Bernad
2. Articles published in Canadian Journal of
   Surgery in 2010
3. An article about hospital construction in the
   journal Modern Healthcare
Applying Limits
Limits
• Filter your search results using practical screens

  Examples:
  Date range        Articles published in the last five years

  Type of article   Only review articles

  Age group         All infants

  Species           Only articles about humans
Demo
•   You need to find a case report, published in
    French or English over the last five years of
    pregnancy in lupus nephritis.
Exercise
Using Limits, find:
1. Review articles on electrocardiography for
   left ventricular hypertrophy published in the
   past two years
2. Clinical trials on perioperative anxiety in
   children
3. An English language practice guideline for
   treating postoperative pain

    TIP: REMOVE your Limits after each search
Save searches
Create a My NCBI Account
A free account with My NCBI will allow you to:

1. Save your searches
2. Create reference lists
3. Set-up email updates of new search results
Demo
• Save and set up a monthly email alert to the
  search for lupus nephritis case studies in
  pregnancy
Exercise
• Register for a My NCBI account (must verify
  via email)
• Run a search on a topic of interest to you
• Save your search and set up an email alert
  (optional)
Recap – Fill in the Blanks
• PubMed is a ___ information resource
• Combine synonymous search terms with ___
• Search ___ when the publisher link doesn’t find
  the full text
• Increase the relevancy of searches with ___
• Find an article by a particular author with ___
• Use ___ to screen results by publication type
• To set up email alerts, ____ your search

PubMed Essentials

  • 1.
    PubMed Essentials Feb 22, 2011 ROBIN FEATHERSTONE, SLIDES: www.slideshare.net/featherr
  • 2.
    Levels of EvidencePyramid Systematic Reviews of Less Time Randomized Controlled Trials Less Work Less Evidence Critically Appraised Topics FILTERED Randomized Controlled Trials Cohort Studies & Case Reports UNFILTERED More Time Case Controlled More Work Studies More Evidence
  • 3.
    Needs Assessment • How often do you use PubMed? • Why do you use it? • What are you looking for? • What (if any) problems have you encountered?
  • 4.
    Objectives After this class,you’ll be able to do the following in PubMed: 1. Execute a simple search 2. Locate full text 3. Use subject headings 4. Use Single Citation Matcher 5. Apply limits 6. Save searches
  • 5.
  • 6.
    What are youlooking for? Well… I’m working on this research team and we’re investigating the use of magnesium sulfate as a possible mechanism for improving neurological outcomes after acute Identify your traumatic brain injury in key concepts: young adults. We’d like to know what studies have been conducted.
  • 7.
    Find the keyconcepts… 1. What are risk factors for myocardial infarction as a postoperative complication after infrarenal infrarenal abdominal aortic aneurysm repair? repair 2. Are childhood cancer survivors more likely to have gastrointestinal complications later in life? 3. What impact does population density have on population density incidence of Type II Diabetes Diabetes?
  • 8.
    Combining search terms •Use OR to find MORE results on the same concept ex. heart attack OR myocardial infarction • Use AND to find LESS results using two or more concepts ex. heart attack AND diet therapy
  • 9.
    AND or OR? A.myocardial infarction B. infrarenal abdominal aortic aneurysm repair
  • 10.
    AND or OR? A.myocardial infarction B. infrarenal abdominal aortic aneurysm repair AND
  • 11.
    Exercise: Search PubMedusing these terms with either AND or OR 1. myocardial infarction ? heart attack 2. diet therapy ? caloric restriction 3. childhood cancer ? gastrointestinal complications 4. population density ? Type II Diabetes
  • 12.
  • 13.
    Where to gofrom here?
  • 14.
    3 Ways toFind Full Text 1. Select the publisher link in PubMed 2. Search the journal name in the McGill Library catalogue
  • 15.
    3 Ways toFind Full Text, cont… 3. Request it from us! http://muhclibraries.mcgill.ca/
  • 16.
    Exercise • Conduct aquick search in PubMed on complications following laparoscopic robotic hysterectomy • Locate two full text articles
  • 17.
  • 18.
    Medical Subject Headings(MeSH) • MeSH Terms are added to references to describe the subject of these articles • Search with MeSH Terms to increase the relevancy of your results
  • 19.
    Search Using MeSH • Identify key concepts • Search MeSH database to find MeSH Terms • Send terms to the Search Box with AND or OR • Search PubMed
  • 20.
    Demo Using MeSH, findarticles about cardiac catheterization methods for patients awaiting a heart transplant
  • 21.
    Exercise & 10min Break Using MeSH, find articles on the following: 1. NSAIDS for rheumatoid arthritis during pregnancy 2. Metformin for breast cancer prevention Bonus – immunosuppression for HIV infected patients following kidney transplantation
  • 22.
    Objectives After this class,you’ll be able to do the following in PubMed: 1. Execute a simple search 2. Locate full text 3. Use subject headings 4. Use Single Citation Matcher 5. Apply Limits 6. Save searches
  • 23.
    Scenario You’re looking for: •A particular article • Articles written by a specific author • Articles published in a particular journal
  • 24.
    Demo • Find anarticles published in 2011 in the journal Diagnostic Cytopathology about fibroadenoma of the breast
  • 25.
    Exercise • Using Single Citation Matcher find: 1. Articles written by Daniel M. Bernad 2. Articles published in Canadian Journal of Surgery in 2010 3. An article about hospital construction in the journal Modern Healthcare
  • 26.
  • 27.
    Limits • Filter yoursearch results using practical screens Examples: Date range Articles published in the last five years Type of article Only review articles Age group All infants Species Only articles about humans
  • 28.
    Demo • You need to find a case report, published in French or English over the last five years of pregnancy in lupus nephritis.
  • 29.
    Exercise Using Limits, find: 1.Review articles on electrocardiography for left ventricular hypertrophy published in the past two years 2. Clinical trials on perioperative anxiety in children 3. An English language practice guideline for treating postoperative pain TIP: REMOVE your Limits after each search
  • 30.
  • 31.
    Create a MyNCBI Account A free account with My NCBI will allow you to: 1. Save your searches 2. Create reference lists 3. Set-up email updates of new search results
  • 32.
    Demo • Save andset up a monthly email alert to the search for lupus nephritis case studies in pregnancy
  • 33.
    Exercise • Register fora My NCBI account (must verify via email) • Run a search on a topic of interest to you • Save your search and set up an email alert (optional)
  • 34.
    Recap – Fillin the Blanks • PubMed is a ___ information resource • Combine synonymous search terms with ___ • Search ___ when the publisher link doesn’t find the full text • Increase the relevancy of searches with ___ • Find an article by a particular author with ___ • Use ___ to screen results by publication type • To set up email alerts, ____ your search

Editor's Notes

  • #9  There are 2 commands (called Boolean operators) used to combine search terms – OR, AND. OR is used to search for related terms; the journal article may be about either term, so you will increase the number of your search results, e.g., exercise or walking (GB suppl. note: 20 articles, 1 overlap = you obtain 19 articles with OR, 1 article with AND) AND is used to retrieve articles that are about all your search terms; you will decrease the number of your search results using AND. If we wanted articles that discussed both cross infection and knowledge transfer, we would combine both subject headings with AND. Note that we tend to say AND in the English language when we mean OR, e.g., I want English and French articles. When I say this, I really mean that I want publications in either language, English or French. If I used AND in my search strategy, I would obtain only references to bilingual articles, very few or non-existent. (Show them how to combine the search sets from previous exercises.)1- exp Cross Infection/ 20658 2- exp "Diffusion of Innovation“/ 9720 3- 1 and 2 17