This document provides guidance on conducting literature searches and reviews. It discusses choosing search terms, developing a search strategy worksheet, searching bibliographic databases like PubMed and EMBASE, applying limits, and evaluating search results. Screenshot examples from PubMed demonstrate how to use Medical Subject Headings (MeSH) to search for and combine concepts. Useful references and websites for literature searching are also listed. The overall aim is to guide researchers in developing an effective, systematic approach for comprehensively searching the existing literature.