This document provides an overview and instructions for using PubMed, a database from the National Library of Medicine that includes MEDLINE and life science journals. It outlines the learning outcomes for a class on PubMed, which include being able to identify full-text availability, use Medical Subject Headings (MeSH) terms, limit and expand searches, use Boolean operators, and locate related resources. Step-by-step instructions are provided for conducting searches in PubMed and finding full-text articles.