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Dr. Sandeep Kumar Raghuvanshi
Department of Zoology
Bareilly College, Bareilly
•Polygene is when a dominant allele controls only a unit or partial
quantitative expression of a trait.
•Several non-allelic genes affect same character.
•Also called multiple gene or quantitative or cumulative inheritance
as trait becomes more pronounced when dominant alleles are added.
•Each gene contributes equally.
•Environmental factors may also effect.
•Does not follow Mendelian ratio.
•Examples include skin color in human, kernel color on wheat,
human height, cob length in maize, etc.
Joseph Gottlieb Koleuter : Father of polygenic inheritance
Herman Nilsson-Elhe and East : First to discover polygenic
inheritance in kernel color in wheat
Charles B. Davenport and Gertrude C. Devenport:
Discovered that the inheritance of skin color in human occurs
by p
J.B Koleuter H Nilsson C.B Davenport
=*=--• ------A • • 1 __I ^
in pigmentation in human
Trait
Distribution
Proportion of population
7T
D*
"O
to’
Though melanin production is regulated by 3 genes as above, for
convenience, we consider only two pairs of genes.
AABB
Parents
Negro
aabb
Albino
Gametes AB ab
FI generati»n Mullato
Fi
Gametes
AB Ab aB ab
AB AABB
Negro
AABb
Dark
AaBB
Dark
AaBb
Mulatto
Ab AABb
Dark
AAbb
Mulatto
AaBb
Mulatto
Aabb
Fair
aB AaBB
Dark
AaBb
Mulatto
aaBB
Mulatto
aaBb
Fair
ab AaBb
Mulatto
Aabb
Fair
aaBb
Fair
aabb
Albino
F2 generation phenotypic Ratio= 1: 4: 6: 4: 1
Gene 1 d'd1 d1D1 d'D' D'D1 D’d1
D1d» D'D1
Gene 2 d2d2 d2d2 d2D2 D2d2 D2d2 D2D2
D2D2
Gene 3 d3d3 d3d3 d3d3 d3d3 D3D3 D3D3 D3D3
Total 0 1 2 3 4 5 6
numberof
dark-skin
genes
Medium Very
dark
# of light
“d" alleles
U of dark
UD’
alleles
5
1
Kernel Color in Wheat
aa bb cc x AA BB CC
(pure white line) (pure red line)
l
Aa Bb Cc (medium red)
Self-fertilization
aabbcc
AAbbcc AaBbcc
aaBBcc Aabbcc
AabbCc aaBbcc
aabbCC aabbCc
aaBbCc
AABbcc
AAbbCc AABBcc AaBBcc AABbCc
AabbCC AAbbCC aaBBCc AaBbCC
AABBCc aaBbCC aaBBCC AaBBCC
AaBbCc AaBBCc AABbCC AABBCC
0 1 2 3 4 5 6
Number of red pigment alleles (A, B or C) in genotype
AABb
DARK
AaBB
OARK
AaBt>
MEOIUM
AABB AABb AaBB AaBb
RED OARK DARK MEOIUM
AAbb AaBb Aabt
MEOIUM MEDIUM LIGHT
AaBb aaBB aaBb
MEOIUM MEOIUM LIGHT
Aabb aaBb aabb
LIGHT LIGHT WHITE
REO
AABB
1
WHITE
aabb
i
ab
Parents
Gametes ► AB
F* Generation MEOIU
M
AaBb
Gametes
F2 generation phenotypic Ratio=1:4:6:4:1
Mother
Human Eye Color
Father
AaBb
AB Ab aB ab
AB
•
AABB
•
AABb
•
AaBB
9
AaBb
Ab
•
AABb
#
A Abb AaBb
#
Aabb
aB
•
AaBB
m
AaBb
#
aaBB
•
aaBb
ab
#
AaBb
#
Aabb
#
aaBb
#
aabb
onogenic v/s Polygenic Inheritance
Monogenic Inheritance Polygenic Inheritance
Monogenic Inheritance Polygenic Inheritance
Discontinuous variation Continuous variation
Single allelic gene Many non-allelic genes
Qualitative inheritance Quantitative inheritance
F1 individual resembles
dominant parent
F1 individual are intermediate
between the parents
Phenotype not influenced by
environment
Phenotype influenced by
environment
No intermediates Numerous intermediates
Eg: All seven characters studied
by Mendel
Eg: Skin color in human, Wheat
kernel color, etc.
YOU!

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Polygenes and their inheritance pattern.pptx

  • 1. Dr. Sandeep Kumar Raghuvanshi Department of Zoology Bareilly College, Bareilly
  • 2. •Polygene is when a dominant allele controls only a unit or partial quantitative expression of a trait. •Several non-allelic genes affect same character. •Also called multiple gene or quantitative or cumulative inheritance as trait becomes more pronounced when dominant alleles are added. •Each gene contributes equally. •Environmental factors may also effect. •Does not follow Mendelian ratio. •Examples include skin color in human, kernel color on wheat, human height, cob length in maize, etc.
  • 3. Joseph Gottlieb Koleuter : Father of polygenic inheritance Herman Nilsson-Elhe and East : First to discover polygenic inheritance in kernel color in wheat Charles B. Davenport and Gertrude C. Devenport: Discovered that the inheritance of skin color in human occurs by p J.B Koleuter H Nilsson C.B Davenport
  • 4. =*=--• ------A • • 1 __I ^ in pigmentation in human
  • 6. Though melanin production is regulated by 3 genes as above, for convenience, we consider only two pairs of genes. AABB Parents Negro aabb Albino Gametes AB ab FI generati»n Mullato
  • 7. Fi Gametes AB Ab aB ab AB AABB Negro AABb Dark AaBB Dark AaBb Mulatto Ab AABb Dark AAbb Mulatto AaBb Mulatto Aabb Fair aB AaBB Dark AaBb Mulatto aaBB Mulatto aaBb Fair ab AaBb Mulatto Aabb Fair aaBb Fair aabb Albino F2 generation phenotypic Ratio= 1: 4: 6: 4: 1
  • 8. Gene 1 d'd1 d1D1 d'D' D'D1 D’d1 D1d» D'D1 Gene 2 d2d2 d2d2 d2D2 D2d2 D2d2 D2D2 D2D2 Gene 3 d3d3 d3d3 d3d3 d3d3 D3D3 D3D3 D3D3 Total 0 1 2 3 4 5 6 numberof dark-skin genes Medium Very dark # of light “d" alleles U of dark UD’ alleles 5 1
  • 9. Kernel Color in Wheat aa bb cc x AA BB CC (pure white line) (pure red line) l Aa Bb Cc (medium red) Self-fertilization aabbcc AAbbcc AaBbcc aaBBcc Aabbcc AabbCc aaBbcc aabbCC aabbCc aaBbCc AABbcc AAbbCc AABBcc AaBBcc AABbCc AabbCC AAbbCC aaBBCc AaBbCC AABBCc aaBbCC aaBBCC AaBBCC AaBbCc AaBBCc AABbCC AABBCC 0 1 2 3 4 5 6 Number of red pigment alleles (A, B or C) in genotype
  • 10. AABb DARK AaBB OARK AaBt> MEOIUM AABB AABb AaBB AaBb RED OARK DARK MEOIUM AAbb AaBb Aabt MEOIUM MEDIUM LIGHT AaBb aaBB aaBb MEOIUM MEOIUM LIGHT Aabb aaBb aabb LIGHT LIGHT WHITE REO AABB 1 WHITE aabb i ab Parents Gametes ► AB F* Generation MEOIU M AaBb Gametes F2 generation phenotypic Ratio=1:4:6:4:1
  • 11. Mother Human Eye Color Father AaBb AB Ab aB ab AB • AABB • AABb • AaBB 9 AaBb Ab • AABb # A Abb AaBb # Aabb aB • AaBB m AaBb # aaBB • aaBb ab # AaBb # Aabb # aaBb # aabb
  • 12. onogenic v/s Polygenic Inheritance Monogenic Inheritance Polygenic Inheritance Monogenic Inheritance Polygenic Inheritance Discontinuous variation Continuous variation Single allelic gene Many non-allelic genes Qualitative inheritance Quantitative inheritance F1 individual resembles dominant parent F1 individual are intermediate between the parents Phenotype not influenced by environment Phenotype influenced by environment No intermediates Numerous intermediates Eg: All seven characters studied by Mendel Eg: Skin color in human, Wheat kernel color, etc.
  • 13. YOU!