Phytochemical Analysis Of Plants Product And Study It's Biological Activities Widely used in the human therapy, veterinary, agriculture, scientific research and countless other areas Have inhibitory effects on all types of microorganisms in vitro
The importance of medicinal plants in the treatment of a variety of human ailments man has been dependent on the higher plants as a source of food and medicine.
A purified and standardized fraction with a defined minimum of four bioactive or phytochemical compounds of an extract of a medicinal plant or its part, for internal or external use of human beings or animals for diagnosis, treatment, mitigation, or prevention of any diseases but does not include administration by parenteral route.
This presentation comprehensively tells about not only the classical methods of extraction but also the modern methods by which herbal products can be easily and efficiently extracted for further use in isolation and formulation
Free radicals: are compounds that have an odd (uneven) number of electrons and therefore unbalanced and reactive (stealing an electron from compounds they encounter to gain stability)
Antioxidants: are compounds that offer an electron to free radicals to neutralize their destructive nature
The importance of medicinal plants in the treatment of a variety of human ailments man has been dependent on the higher plants as a source of food and medicine.
A purified and standardized fraction with a defined minimum of four bioactive or phytochemical compounds of an extract of a medicinal plant or its part, for internal or external use of human beings or animals for diagnosis, treatment, mitigation, or prevention of any diseases but does not include administration by parenteral route.
This presentation comprehensively tells about not only the classical methods of extraction but also the modern methods by which herbal products can be easily and efficiently extracted for further use in isolation and formulation
Free radicals: are compounds that have an odd (uneven) number of electrons and therefore unbalanced and reactive (stealing an electron from compounds they encounter to gain stability)
Antioxidants: are compounds that offer an electron to free radicals to neutralize their destructive nature
Emblica is very important medicinal plant.It is also called Indian goose berry ,rich in vitamin c belongs to the family Euphorbiaceae,very much used in Ayurveda.
It contains information regarding five medicinal plants - Aloe vera, Cranberry, Clove, Lavender, Turmeric. Their Binomial classification, introduction and their uses.
INDUSTRIAL PHARMACOGNOSTICAL TECHNOLOGY
Herbal drug industry: Infrastructure of herbal drug industry
involved in production of standardized extracts and various
dosage forms. Current challenges in upgrading and
modernization of herbal formulations. Entrepreneurship
Development, Project selection, project report, technical
knowledge, Capital venture, plant design, layout and construction.
Pilot plant scale –up techniques, case studies of herbal extracts.
Formulation and production management of herbals.
These slides represent a comprehensive view of history of using natural products caused to appearance of pharmacognosy as a science and show several aspects of pharmacognosy and natural products use and final their importance in discovering new drugs.
n Ayurveda, withania is widely claimed to have potent aphrodisiac, sedative, rejuvenative and life prolonging properties. It is also used as a general energy-enhancing tonic known as Medharasayana, which means 'that which promotes learning and a good memory' and in geriatric problems.
Ethnobotany and Ethnopharmacology-Approaches of Traditional Medicine Studies, Traditional use & management of medicinal plants in Asian countries, Application of Ethnobotany to community conservation and medicinal plant resource management
method to separate compounds based on their relative solubilities in two different immiscible liquids, usually water and an organic solvent. It is an extraction of a substance from one liquid into another liquid phase.
Emblica is very important medicinal plant.It is also called Indian goose berry ,rich in vitamin c belongs to the family Euphorbiaceae,very much used in Ayurveda.
It contains information regarding five medicinal plants - Aloe vera, Cranberry, Clove, Lavender, Turmeric. Their Binomial classification, introduction and their uses.
INDUSTRIAL PHARMACOGNOSTICAL TECHNOLOGY
Herbal drug industry: Infrastructure of herbal drug industry
involved in production of standardized extracts and various
dosage forms. Current challenges in upgrading and
modernization of herbal formulations. Entrepreneurship
Development, Project selection, project report, technical
knowledge, Capital venture, plant design, layout and construction.
Pilot plant scale –up techniques, case studies of herbal extracts.
Formulation and production management of herbals.
These slides represent a comprehensive view of history of using natural products caused to appearance of pharmacognosy as a science and show several aspects of pharmacognosy and natural products use and final their importance in discovering new drugs.
n Ayurveda, withania is widely claimed to have potent aphrodisiac, sedative, rejuvenative and life prolonging properties. It is also used as a general energy-enhancing tonic known as Medharasayana, which means 'that which promotes learning and a good memory' and in geriatric problems.
Ethnobotany and Ethnopharmacology-Approaches of Traditional Medicine Studies, Traditional use & management of medicinal plants in Asian countries, Application of Ethnobotany to community conservation and medicinal plant resource management
method to separate compounds based on their relative solubilities in two different immiscible liquids, usually water and an organic solvent. It is an extraction of a substance from one liquid into another liquid phase.
extraction of bioactive compounds from plant sources using maceration processNivaasvignopathy
extraction of bioactive compounds from plant sources using maceration process.Maceration is a technique used in wine making and has been adopted in medicinal plant research.
Soxhlet extraction is a continuous process of extraction with a hot organic solvent. Typically, Soxhlet extraction is used when the desired compound has a limited solubility in a solvent, and the impurity is insoluble in that solvent.
Soxhlet extraction is a continuous process of extraction with a hot organic solvent.
Typically, Soxhlet extraction is used when the desired compound has a limited solubility in a solvent, and the impurity is insoluble in that solvent.
This is about the large extraction, hope you all get benefit from this and feel easy to use it .
This is all about how we do extraction at large scale and what is the best procedure to do it properly, as a pharmacist we must know about little details of our formulations how they are extracted and their further process and machinery used. All the terms should be considered and handling is the most important step. This will be a ready to explain type information.
The process of separating medicinally active constituents of plant and animal tissues with the help of selective solvents and standard procedures is termed extraction.
The extracted products of plant tissues obtained in liquid or semisolid state (after removing the solvent) or in dry powdered form are complex mixtures of metabolites.
The extracted preparations include decoctions, infusions, fluid extracts, tinctures, semisolid extracts, or powdered extracts; these preparations are named as galenicals after Galen (a Greek physician of 2nd century)
The standardised extraction procedures involve treatment with a selective solvent (menstrum) to yield the therapeutically active constituents of crude drugs, removing the inactive ones.
The undissolved residue left behind is termed marc.
Extraction
Various methods
Extraction with reflux
Extraction with agitation
Counter current extraction
reserve percolation process, continuous hot percolation process
decoction
infusion
digestion
Extraction with agitation
Maceration with adjustment
All about extraction methods in pharmacognosy.
The procedure of separating active compounds, active substances, or active medications from basic materials derived either directly from plants or animals,
It is the separation of medicinally active tissues from inert or inactive components in plants or animals using specific solvents.
Solvent ;
Can be Polar or Non-polar
Depends on the nature of secondary metabolite
Example;
Polar Solvents; Water, Alcohol etc.
Non- polar; Benzene, chloroform etc.
Ideal properties of the solvent;
Must be highly selective for the compound to be extracted
Inert with the extracted compound or with other compounds in the plant material
Cost effective
Be harmless to man & eco-friendly
CHOICE OF EXTRACTION METHODS DEPENDS ON;
Size of Sample
Quantity of the extract required
Choice of solvent
The time taken for extraction
Cost
Terms used in extraction;
MENSTRUUM;
Solvent or solvent mixture used for extraction.
MISCELLA /Extract;
Solution containing extracted substances.
MARC;
Inert insoluble material that remains after extraction.
Drying of crude drugs;
To prevent microbiological contamination, it is necessary.
Drugs should be dried below 60°C unless otherwise specified.
Shade drying
Lowered heat exposure
Less chance to chemical alteration
Sun drying
Use less intense sun light
Economic, Most efficient
Far infrared drying
Less explored yet
Expensive, Used for expensive drugs
Vacuum Drying
Low Pressure rapid drying method
For thermolabile compounds
Oven/Hot air drying
Often used
Steps of Extractions;
Size reduction
Maximum surface area
Mesh size is 30-40 optimum
Extraction
Maceration, Infusion, Percolation, soxhlation etc.
Filtration
With the help of musciline cloth, filter paper, filter press
Concentration
By evaporation of solvent
Drying
Spray drying
Extraction;
Extraction is the process of efficiently dissolving & separating the desired chemical constituents from the crude drug with the use of solvent.
Types Of Extraction ;
Solid Extraction
The name refers to the separation of solid components from solid substance by using appropriate solvent. This type of extraction is generally performed before any further separation or processing..
2. Solvent Extraction
The liquid-liquid extraction is one in which phytoconstituents that are extracted by solid extraction process are partitioned between any two immiscible solvents.
Ideally this process needs to be carried out after solid extraction process & it is considered as purification process.
On a laboratory scale Solvent extraction is carried out in a separating funnel.
Mechanism of .......
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
The increased availability of biomedical data, particularly in the public domain, offers the opportunity to better understand human health and to develop effective therapeutics for a wide range of unmet medical needs. However, data scientists remain stymied by the fact that data remain hard to find and to productively reuse because data and their metadata i) are wholly inaccessible, ii) are in non-standard or incompatible representations, iii) do not conform to community standards, and iv) have unclear or highly restricted terms and conditions that preclude legitimate reuse. These limitations require a rethink on data can be made machine and AI-ready - the key motivation behind the FAIR Guiding Principles. Concurrently, while recent efforts have explored the use of deep learning to fuse disparate data into predictive models for a wide range of biomedical applications, these models often fail even when the correct answer is already known, and fail to explain individual predictions in terms that data scientists can appreciate. These limitations suggest that new methods to produce practical artificial intelligence are still needed.
In this talk, I will discuss our work in (1) building an integrative knowledge infrastructure to prepare FAIR and "AI-ready" data and services along with (2) neurosymbolic AI methods to improve the quality of predictions and to generate plausible explanations. Attention is given to standards, platforms, and methods to wrangle knowledge into simple, but effective semantic and latent representations, and to make these available into standards-compliant and discoverable interfaces that can be used in model building, validation, and explanation. Our work, and those of others in the field, creates a baseline for building trustworthy and easy to deploy AI models in biomedicine.
Bio
Dr. Michel Dumontier is the Distinguished Professor of Data Science at Maastricht University, founder and executive director of the Institute of Data Science, and co-founder of the FAIR (Findable, Accessible, Interoperable and Reusable) data principles. His research explores socio-technological approaches for responsible discovery science, which includes collaborative multi-modal knowledge graphs, privacy-preserving distributed data mining, and AI methods for drug discovery and personalized medicine. His work is supported through the Dutch National Research Agenda, the Netherlands Organisation for Scientific Research, Horizon Europe, the European Open Science Cloud, the US National Institutes of Health, and a Marie-Curie Innovative Training Network. He is the editor-in-chief for the journal Data Science and is internationally recognized for his contributions in bioinformatics, biomedical informatics, and semantic technologies including ontologies and linked data.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
1. TOPIC- Extraction And Phytochemical
Analysis Of Plants Product And Study
It's Biological Activities
Presented By:-
Abhishek Mahapatra
M.Sc
Subject- Industrial Chemicals
2. PHYTOCHEMICAL
Phytochemical are compounds that are produced by plants ("phyto" means "plant").
Natural bioactive compounds found in different parts of plant (fruit, flower, stem, leaf, root)
Widely used in the human therapy, veterinary, agriculture, scientific research and countless
other areas
Have inhibitory effects on all types of microorganisms in vitro
3. EXTRACTION
Extraction may be defined as the treatment of the plant or animal tissues with
solvent, whereby the medicinally active constituents are dissolved, and most of the
inert matter remains undissolved.
The solvent used for extraction is known as Menstruum and the inert insoluble
material that remains after extraction is called Marc.
4. TYPES OF EXTRACTION
1. Maceration
2. Percolation
3. Soxhlet Extraction
4. Water distillation
5. Steam distillation
5. MACERATION
In this process, the whole or coarsely powdered crude drug is placed in a stopper
container with the solvent and allowed to stand at room temperature for a period of at
least 3 days with frequent agitation until the soluble matter has dissolved.
The mixture then is strained, the marc (the damp solid material) is pressed, and the
combined liquids are clarified by filtration or decantation after standing.
6. PERCOLATION
Percolation is a continuous flow of the solvent through the
bed of the crude drug material to get the extract.
In this process, the powdered drug is moistened with an
appropriate amount of the specified menstruum and allowed
to stand for approximately 4 h in a well closed container,
after which the mass is packed and the top of the percolator
is closed.
Additional menstruum is added to form a shallow layer
above the mass, and the mixture is allowed to macerate in the
closed percolator for 24hrs.
7. CONT…
The outlet of the percolator then is opened and the liquid contained therein is allowed
to drip slowly.
Additional menstruum is added as required, until the percolate measures about three-
quarters of the required volume of the finished product
The marc is then pressed and the expressed liquid is added to the percolate.
Sufficient menstruum is added to produce the required volume, and the mixed liquid
is clarified by filtration or by standing followed by decanting
8. SOXHLET EXTRACTION
A Soxhlet extraction is only required where the
desired compound has a limited solubility in a
solvent, and the impurity is insoluble in that
solvent.
It is also known as counter current extraction.
9. CONT…
Drug is formed in to powder and the solvent is mixed in to it in equal quantity place
in apparatus and evaporate with heat condensation takes place,vapors are collected.
The thimble is loaded into the main chamber of the Soxhlet extractor. The extraction
solvent to be used is placed in a distillation flask.
The flask is placed on the heating element. The Soxhlet extractor is placed atop the
flask. A reflux condenser is placed atop the extractor
10. WATER DISTILLATION
This method is useful for the extraction of essential oils
Distilled water is water that has had many of its impurities removed through
distillation. Distillation involves boiling the water and then condensing the steam into
a clean container.
Applications - In chemical and biological laboratories, as well as in industry,
cheaper alternatives such as deionized water are preferred to distilled water.
But if these alternatives are not pure enough, distilled water is used.
11.
12. STEAM DISTILLATION
Steam distillation is a special type of distillation (a separation process) for
temperature sensitive materials like natural aromatic compounds.
It once was a popular laboratory method for purification of organic compounds,
but has become obsolete by vacuum distillation.
14. BIOLOGICAL ACTIVITIES
Biological activities of plant phytochemicals including
1. Anti-oxidant- Man-made or natural substances that may
prevent or delay some types of cell damage.
2. Anti-microbial- An agent that kills microorganisms or stops
their growth.
3. Anti-fungal- Medicines that kill or stop the growth of fungi.
15. CONCLUSION
Extraction, as the term is used pharmaceutically, involves the separation of
medicinally active portions of plant or animal tissues from the inactive or inert
components by using selective solvents in standard extraction procedures.
The products so obtained from plants are relatively impure liquids, semisolids or
powders intended only for oral or external use.