This document discusses the principles of physics of diagnostic radiology. It describes the structure of atoms including the nucleus containing protons and neutrons, and electrons orbiting in shells. Electrons have binding energies that increase with atomic number and decrease with increasing shell number. Ionization occurs when energy is applied to eject an electron from its shell, creating a vacancy. Excited atoms undergo rearrangement as electrons transition between shells to fill vacancies, and may emit electromagnetic radiation in the process.