The document outlines the roles and functions of the Pharmacy and Therapeutic Committee (PTC) in hospitals, which includes formulating drug use policies, ensuring drug safety, and monitoring adverse drug reactions. It emphasizes the need for qualified pharmacists and educational support for medical staff, as well as the development of emergency drug lists. The document also details procedures for reporting adverse drug reactions and the establishment of guidelines for medication management.

1. P R E P A R E D B Y :
S H I V A N E E V Y A S
M . P H A R M A C Y
Pharmacy and therapeutic
committee
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Prepared by:
Shivanee Vyas
M. Pharmacy

2. committee
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3. contents
 Introduction
 Role of pharmacy and therapeutic committee
 PTC composition
 Functions
 Role of PTC in drug safety
 Role of PTC in adverse drug reaction
monitoring
 Role of PTC and emergency drug list
 Role of PTC in drug utilization programme
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4. Introduction
The pharmacy and therapeutic committee is a group of
persons which formulate policies regarding therapeutic
use of drugs. This committee is composed of physician
pharmacists and other health professional with the
inclusion of the medical staff.
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5. ROLE OF PTC
 ADVISORY:
• They assist in the formulation of broad of professional policies
regarding evaluation, selection and therapeutic use of drug in
hospital.
• The committee has an advisory capacity to medical staff and
hospital administration in all matters regarding the use of drug.
• It makes recommendation concerning the drugs to be stocked in
hospital patient care area.
 EDUCATIONAL:
• The committee evaluates the problem related to the distribution
and administration of medication including medical incident.
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6. ROLE OF PTC
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• They assist in the need of professional staff like the
physician, nurse, pharmacist and other health care
practitioners for the complete knowledge related to the
drugs and their use.
• The committee should minimize duplication of some
basic drugs and cost.
 Drug safety and Adverse drug monitoring:
• As the therapeutic agents are increasing, the scope,
knowledge and responsibility if the hospital is also
increasing.

7. Pharmacy and therapeutic committee
 Medical staff department of pharmacy
Sub
commit
tee(neo
plastic)
Sub
committ
ee(anti
infective)
Sub
committee
1 cvs
2 diuretics
3 vasodilator
4 spasmolytic
5 anti
coagulants
Sub
committee
1 sedative
2 CNS agents
3 analgesic
4 antipyretics
5 respiratory
6 cerebral
stimulants
Sub
committee
1 GIT
2
autonomic
drugs
3 laxatives
Sub committee
1 hormones
2.Thyroid
3.anti-
inflammatory
4
endocrinology
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8. FUNCTIONS
 Prevent unnecessary loading of drugs, prescribing and to
promote rational therapeutic guideline.
 Medication errors and adverse drug reaction monitoring.
 Visit the outside manufacturing units before approving their
products to the hospital purchase list.
 Written policies and procedure for the selection, procurement,
storage, distribution and use of drugs.
 Recommended the level of stock for each medicine to be
maintained.
 Checking the pharmacy record and drug quality.
 To establish or plan suitable educational schemes for the
hospital professional staff on the matter related to the
use of drugs.
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9. Role of PTC in drug safety
 The hospital must employ a qualified and registered pharmacist with at
least B Pharmacy degree as chief pharmacist and the rest with at least D.
Pharmacy degree.
 The pharmacists should be aware of narcotic and psychotropic drugs.
 The hospital should not permit non-pharmacy person to dispense drugs.
 Does the hospital provide adequate, safe work space and storage
facilities for the pharmacy.
 Is there proper regulation of dangerous drugs.
 Are the poisons and poisonous material adequately separated from non
poisonous material in the pharmacy and in wards.
 The pharmacy should have adequate references library texts on
pharmacology, toxicology, posology and gernals containing adequate
information of pharmaceutical world.
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10. Role of PTC in adverse drug reaction monitoring
 An ADR is defined as any unusual and unexpected
harmful reaction including actual poisoning by narcotics,
barbiturates and amphetamines.
 Every case of adverse reaction must be reported by the
physician to the chairman of pharmacy and therapeutic
committee. physicians should provide complete adverse
reaction report, name of drug, route of administration,
date of starting and ending the treatment, use, adverse
reaction and steps to treat.
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11. PROFORMA FOR MONITORING OF ADR IN
INDIA
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1. Do not leave any section blank.
2. Mark tick in the appropriate box.
3. Type or write in BLOCK LETTERS.
1. Center Name……………………………………….
2. Type of Patient 1. Inpatients 2. Outpatients
3. Serial no……………………………………………..
4. Name of the Patient……………………………..
5. Address (complete)..……………Pin code…..
6. Age……..(Years)
7. Gender 1. Male 2. Female
8. Occupation………………………………………….
9. Hospital record no……………………………….
10. Registration date…………………………………

12. PROFORMA FOR MONITORING OF ADR IN
INDIA
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11. Dietary habit 1. Veg 2. Non-Veg
12. Smoking habit 1. No 2. Yes
If yes duration (years)
13. Alcoholic habit 1. No 2. Yes
If yes details
14. Relevant medical history
- Allergy 1. No 2. Yes
- Environmental exposure 1. No 2. Yes
- Previous drug reaction 1. No 2. Yes
- Family history of ADR 1. No 2. Yes
15. Background sign/symptoms……………………………..
16. Treatment schedule
Drug name Indication Total daily dose route Duration

13. PROFORMA FOR MONITORING OF ADR IN
INDIA
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17. Date of End of Treatment
18. Outcome of end of treatment
1) Recovery 2) Still under medication 3) Died 4)Lost to
follow up 5) ADR suspected
19. If ADR suspected fill in the PROFORMA – II 1. No 2. Yes
Every case of ADR must first reported by the attending physician to the
chairman of the PTC. The attending physician should complete the ADR
proforma.

14. Role of PTC in developing Emergency Drug List
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It is necessary for the PTC of a hospital to get prepared boxes containing
emergency drugs which should be always available for use at the bed side in
emergency situation.
List of such drugs and supplies should be maintained by the PTC
A) Supplies to be maintained in emergency box:
1. Syringe of various ranges 2 each of 1ml, 2ml and 5ml syringe and 1 each
of 10ml, 20ml syringe.
2. Niddle of 16’, 18’, 20’, 23’, & 26’.
3. Files of breaking the ampules.
4. Tourniquets.

15. Role of PTC in developing Emergency Drug List
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B) Drugs for emergency box
1. Atropine sulphate 0.4 mg/ml
2. Ca gluconate 1g/10ml
3. Aminophyllin 0.25 g/ml
4. Heparin 10,000 units/ml
5. Mannitol injection 25%
6. Epinephrine HCL 1mg/ml
7. Water for injection
C) Supplies for cabinet room
1. Oxygen catheters
2. Sterile suction catheters
3. Each set 12 & 17 venous catheters
4. Razors with blades

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