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PHARMACOTHERAPEUTIC
COMMITTEE (PTC)
1
SUBMITTED BY:
M.L.SUSHMITHA
15AB1T0016
4TH PHARM D
UNDER THE GUIDENCE
G.RAMESH
ASSISTANT PROFESSOR
DEPARTMENT OF PHARMACY PRACTISE
SUBMITTED TO;
SATHEESH.S.GOTTIPATI
DEAN OF ACADEMICS
DEFINITION
 The pharmacy and therapeutics committee(PTC) is an advisory group of
the medical staff and serves as the organizational line of communication
between the medical staff and the pharmacy department.
 The committee is composed of physicians, the pharmacist and the other
health professionals selected with guidance of the medical staff.
 This committee assists in the formulation of broad professional policies
regarding the evaluation, selection, procurement, distribution, use, safety
procedures and other matters relating to drugs use in the hospital.
VIGNAN PHARMACY COLLEGE,VADLAMUDI
2
Functions of PTC:
 Preparation of hospital drug formulary.
 Selection of manufacturer and supplier, mode of procurement.
 Addition of new drugs, deletion of old drugs.
 Drugs to be supplied in OPD.
 Policy formulation for pharmacy and monitoring
 Budget demand for pharmacy
 Developing Drug Information System
 Checking of pharmacy records and drug quality
 Maintenance of drug standard and quality control
 Disposal of Expiry Drug
VIGNAN PHARMACY COLLEGE,VADLAMUDI
3
Composition of PTC:
 At least three physicians
 A pharmacist
 A representative of the nursing staff
 A hospital administrator or his/her designated person and ex-officio member of
the committee
 The physician may be appointed as the “ Chairman ” of P.T.C.
 The pharmacist is designated as the “ Secretary ” of the committee.
VIGNAN PHARMACY COLLEGE,VADLAMUDI
4
Objectives of PTC:
Advisory:
• The committee recommends the
adoption of (or) assists in the
formulation of the broad
profession policies regarding
evaluation, selection and
therapeutic use of drugs in the
hospital.
• The committee serves in an
advisory capacity to medical staff
and hospital administration in all
matters pertaining to the use of
drugs including the
investigational drugs.
Educational:
• The committee recommends or
assists in the formulation of
functions, designed to meet the
needs of the professional staff, the
physicians, nurses, pharmacists and
other health care practitioners, for
the complete current knowledge of
the matters related to drugs and
their uses.
• The committee studies the problems
related to the distribution and
administration of medication.
• It establishes or plans suitable
educational scheme for the hospital
professional staff on the matters
related to the use of drugs.
Drug Safety and
Adverse Drug
Monitoring:
• As the therapeutic agents are
increasing, the scope, knowledge
and responsibility of the hospital
pharmacist is also increasing.
• The safety aspects are more or
less taken for granted by
pharmacy, medical and nursing
staff.
VIGNAN PHARMACY COLLEGE,VADLAMUDI
5
Organization and
Operation of PTC:
• Operation PTC should meet regularly at
least six times in an year and also as and
when necessary.
• The committee can invite its meetings and
persons within or outside the hospital who
can contribute specialized or unique
knowledge and skilled judgment.
• The agenda and the supplementary
materials should be prepared by the
secretary and furnished to the committee
members sufficiently in time before the
meeting.
• The pharmacy and therapeutics committee
should be.composed of at least three
physicians, a pharmacist, a nurse and an
administrator.
VIGNAN PHARMACY COLLEGE,VADLAMUDI
6
Meetings:
 The Pharmacy and Therapeutics Committee shall meet monthly or as otherwise
deemed necessary by the Chair, but not less than quarterly.
 Topics that may be discussed at meetings include:
 New brand or generic drugs
 PDL changes based on any local or national issues (including contract issues)
 Stakeholder feedback through a Public Comment session
VIGNAN PHARMACY COLLEGE,VADLAMUDI
7
Responsibility of PTC:
 Ensure safety medication to patients The preparations of a hospital formulary
 Publishing of a pharmacy educational bulletin, The establishment of automatic
stop orders for dangerous drugs
 The supervision of investigational use drugs
 The development of a program for reporting and investigating adverse drug
reactions
 Assisting in the preparation of emergency kits or carts for medical emergencies
VIGNAN PHARMACY COLLEGE,VADLAMUDI
8
Role of PTC in drug safety:
 Drug safety is the moral, legal and professional obligation of pharmacist .
 It includes responsibility from dispensing of drugs to drug administration .
 Following guidelines may sub serve the committee in ascertaining the adequate
safety factor of hospital pharmacy.
 The hospital must employ a qualified, at least, a registered pharmacist with at least
B. Pharm degree as ‘Chief pharmacist’ and the rest are may be at least diploma
holders in pharmacist.
VIGNAN PHARMACY COLLEGE,VADLAMUDI
9
Role of PTC in drug safety: (CONT)
Following guidelines may subserve the committee in
asertaining the adequate safety factor of the hospital
pharmacy.
 1) A registered pharmacist – chief pharmacist -
diploma holders
 2) Not permit non-pharmacist perssonel
 3) A sufficient numbers of qualified perssonel
 4) Adequate safe, work space, and storage
facilities
 5) Have equipment necessary
 6) Automatic stop order-narcotics, hypnotics, anti
coagulants
 7) Firm policy-research drugs
 8) Drug formulary
 9) Out side its working hours
 10) Poisonous materials- non poisionous materials
 11) External use drugs-internal use drugs
 12) Quality control measures, GMP during processing
 13) Teaching programme
 14) Periodical inspection
 15) Adequate reference library
VIGNAN PHARMACY COLLEGE,VADLAMUDI
10
Role in the adverse drug reaction
program:
 A consequence of recent advances in drug therapy is the proportionate increase in
drug reactions. Reaction caused by blood and plasma products need to be reported
unless a chemical agent other than the basic substance is responsible.
 An adverse Drug Reaction(ADR) Report From, should be prepared by the PTC and
made available on every nursing station.
 Every case of adverse drug reaction must be reported by the attending doctor to the
clinical pharmacologist, if one is available, otherwise to the chairman of PTC.
 The completed ADR from of any having adverse drug reaction, will remove from the
medical record and forward to the chairman or clinical pharmacologist, after discharge
of the patient.
VIGNAN PHARMACY COLLEGE,VADLAMUDI
11
Role of PTC in Developing “Emergency
Drug Lists”:
 Since time factor is of very great urgency to most true emergency situations, it is
absolutely necessary for the PTC of a hospital to get prepared boxes containing
emergency drugs which should be always available readily for use at the bed-side.
 List of such drugs and other supplies should be complied by the committee, and it
should find their place in emergency kits.
VIGNAN PHARMACY COLLEGE,VADLAMUDI
12
Role of PTC in Developing “Emergency
Drug Lists”: (CONT)
Supplies to be maintained in Emergency
Box:
 Syringes of various range Two each of 1 ml.
i.e tuberculin or insulin syringe, 2 ml. syringe
and 5 ml. syringe; and one each of 10ml and
20ml syringe.
 Needles, preferebly two each of 16’, 18’, 20’,
21’, 23’, and 26’,
 Files for breaking the ampoule
 Torniquets
 Airway equipment
 Ryles tube
Drugs for Emergency Box:
 Aminophylline 0.25 g/ml
 Amylnitrite glass capsules for inhalation
 Atropine sulphate 0.4mg/ml
 Caffeine sodium benzoate 0.5g/2 ml.
 Calcium Gluconate 1 g/10 ml vi.
 Digoxin 0.25 mg/ml
 Pentobarbitone 50mg/ml
 Pentzocine
VIGNAN PHARMACY COLLEGE,VADLAMUDI
13
Role of PTC in Developing “Emergency
Drug Lists”: (CONT)
Supplies for Cabinet Utility Room
 Venuous cannulation set.
 Each set 12&17 venous catheters
 Pieces 6’’shock blocks
 Oxygen catheters
 Sterile suction catheters
 Razor with blades
 Package sterile gelatine sponge
 Resuscitation tube
Other emergency supplies
 Resuscitation carts
 Phlebotomy sets
 Oxygen equipments
 Tracheotomy sets
 Dextran and tubing
 Burn sheets
VIGNAN PHARMACY COLLEGE,VADLAMUDI
14
Role of PTC in Drug Product Defect
Reporting Programme:
 The drugs purchased by hospital may be defective in quality. It is for the
committee to get information about the defective drug products and to inform it
first to the manufacturer for appropriate action.
 If satisfactory answer is not obtained from the manufacturer or supplier, it should
be reported to the Food and Drug Control Administration.
VIGNAN PHARMACY COLLEGE,VADLAMUDI
15
Role of PTC in Drug Utilization Review:
 Drug utilization includes prescribing, dispensing, administering and ingesting of
prescription of drugs. Hospital pharmacist should take medication history that
should include following information.
 Medication being taken at the time of admission, during admission, home
remedies (OTC) drugs.
 Drug-allergies and idiosyncrosy towards food products etc.
VIGNAN PHARMACY COLLEGE,VADLAMUDI
16
REFERENCE:
 https://www.medicalcenter.virginia.edu/clinicalstaff/csec/pharmacy.html
 https://www.ashp.org/-/media/assets/policy-guidelines/docs/guidelines/gdl-
pharmacy-therapeutics-committee-formulary
 https://en.wikipedia.org/wiki/Pharmacy_and_Therapeutics
 https://www.blueshieldca.com/bsca/pharmacy/faqs/pharmacy-therapeutics-
committee.sp
VIGNAN PHARMACY COLLEGE,VADLAMUDI
17
VIGNAN PHARMACY COLLEGE,VADLAMUDI
18

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AN OVERVIEW ON PHARMACO THERAPEUTIC COMMITTEE - M.L.SUSHMITHA

  • 1. PHARMACOTHERAPEUTIC COMMITTEE (PTC) 1 SUBMITTED BY: M.L.SUSHMITHA 15AB1T0016 4TH PHARM D UNDER THE GUIDENCE G.RAMESH ASSISTANT PROFESSOR DEPARTMENT OF PHARMACY PRACTISE SUBMITTED TO; SATHEESH.S.GOTTIPATI DEAN OF ACADEMICS
  • 2. DEFINITION  The pharmacy and therapeutics committee(PTC) is an advisory group of the medical staff and serves as the organizational line of communication between the medical staff and the pharmacy department.  The committee is composed of physicians, the pharmacist and the other health professionals selected with guidance of the medical staff.  This committee assists in the formulation of broad professional policies regarding the evaluation, selection, procurement, distribution, use, safety procedures and other matters relating to drugs use in the hospital. VIGNAN PHARMACY COLLEGE,VADLAMUDI 2
  • 3. Functions of PTC:  Preparation of hospital drug formulary.  Selection of manufacturer and supplier, mode of procurement.  Addition of new drugs, deletion of old drugs.  Drugs to be supplied in OPD.  Policy formulation for pharmacy and monitoring  Budget demand for pharmacy  Developing Drug Information System  Checking of pharmacy records and drug quality  Maintenance of drug standard and quality control  Disposal of Expiry Drug VIGNAN PHARMACY COLLEGE,VADLAMUDI 3
  • 4. Composition of PTC:  At least three physicians  A pharmacist  A representative of the nursing staff  A hospital administrator or his/her designated person and ex-officio member of the committee  The physician may be appointed as the “ Chairman ” of P.T.C.  The pharmacist is designated as the “ Secretary ” of the committee. VIGNAN PHARMACY COLLEGE,VADLAMUDI 4
  • 5. Objectives of PTC: Advisory: • The committee recommends the adoption of (or) assists in the formulation of the broad profession policies regarding evaluation, selection and therapeutic use of drugs in the hospital. • The committee serves in an advisory capacity to medical staff and hospital administration in all matters pertaining to the use of drugs including the investigational drugs. Educational: • The committee recommends or assists in the formulation of functions, designed to meet the needs of the professional staff, the physicians, nurses, pharmacists and other health care practitioners, for the complete current knowledge of the matters related to drugs and their uses. • The committee studies the problems related to the distribution and administration of medication. • It establishes or plans suitable educational scheme for the hospital professional staff on the matters related to the use of drugs. Drug Safety and Adverse Drug Monitoring: • As the therapeutic agents are increasing, the scope, knowledge and responsibility of the hospital pharmacist is also increasing. • The safety aspects are more or less taken for granted by pharmacy, medical and nursing staff. VIGNAN PHARMACY COLLEGE,VADLAMUDI 5
  • 6. Organization and Operation of PTC: • Operation PTC should meet regularly at least six times in an year and also as and when necessary. • The committee can invite its meetings and persons within or outside the hospital who can contribute specialized or unique knowledge and skilled judgment. • The agenda and the supplementary materials should be prepared by the secretary and furnished to the committee members sufficiently in time before the meeting. • The pharmacy and therapeutics committee should be.composed of at least three physicians, a pharmacist, a nurse and an administrator. VIGNAN PHARMACY COLLEGE,VADLAMUDI 6
  • 7. Meetings:  The Pharmacy and Therapeutics Committee shall meet monthly or as otherwise deemed necessary by the Chair, but not less than quarterly.  Topics that may be discussed at meetings include:  New brand or generic drugs  PDL changes based on any local or national issues (including contract issues)  Stakeholder feedback through a Public Comment session VIGNAN PHARMACY COLLEGE,VADLAMUDI 7
  • 8. Responsibility of PTC:  Ensure safety medication to patients The preparations of a hospital formulary  Publishing of a pharmacy educational bulletin, The establishment of automatic stop orders for dangerous drugs  The supervision of investigational use drugs  The development of a program for reporting and investigating adverse drug reactions  Assisting in the preparation of emergency kits or carts for medical emergencies VIGNAN PHARMACY COLLEGE,VADLAMUDI 8
  • 9. Role of PTC in drug safety:  Drug safety is the moral, legal and professional obligation of pharmacist .  It includes responsibility from dispensing of drugs to drug administration .  Following guidelines may sub serve the committee in ascertaining the adequate safety factor of hospital pharmacy.  The hospital must employ a qualified, at least, a registered pharmacist with at least B. Pharm degree as ‘Chief pharmacist’ and the rest are may be at least diploma holders in pharmacist. VIGNAN PHARMACY COLLEGE,VADLAMUDI 9
  • 10. Role of PTC in drug safety: (CONT) Following guidelines may subserve the committee in asertaining the adequate safety factor of the hospital pharmacy.  1) A registered pharmacist – chief pharmacist - diploma holders  2) Not permit non-pharmacist perssonel  3) A sufficient numbers of qualified perssonel  4) Adequate safe, work space, and storage facilities  5) Have equipment necessary  6) Automatic stop order-narcotics, hypnotics, anti coagulants  7) Firm policy-research drugs  8) Drug formulary  9) Out side its working hours  10) Poisonous materials- non poisionous materials  11) External use drugs-internal use drugs  12) Quality control measures, GMP during processing  13) Teaching programme  14) Periodical inspection  15) Adequate reference library VIGNAN PHARMACY COLLEGE,VADLAMUDI 10
  • 11. Role in the adverse drug reaction program:  A consequence of recent advances in drug therapy is the proportionate increase in drug reactions. Reaction caused by blood and plasma products need to be reported unless a chemical agent other than the basic substance is responsible.  An adverse Drug Reaction(ADR) Report From, should be prepared by the PTC and made available on every nursing station.  Every case of adverse drug reaction must be reported by the attending doctor to the clinical pharmacologist, if one is available, otherwise to the chairman of PTC.  The completed ADR from of any having adverse drug reaction, will remove from the medical record and forward to the chairman or clinical pharmacologist, after discharge of the patient. VIGNAN PHARMACY COLLEGE,VADLAMUDI 11
  • 12. Role of PTC in Developing “Emergency Drug Lists”:  Since time factor is of very great urgency to most true emergency situations, it is absolutely necessary for the PTC of a hospital to get prepared boxes containing emergency drugs which should be always available readily for use at the bed-side.  List of such drugs and other supplies should be complied by the committee, and it should find their place in emergency kits. VIGNAN PHARMACY COLLEGE,VADLAMUDI 12
  • 13. Role of PTC in Developing “Emergency Drug Lists”: (CONT) Supplies to be maintained in Emergency Box:  Syringes of various range Two each of 1 ml. i.e tuberculin or insulin syringe, 2 ml. syringe and 5 ml. syringe; and one each of 10ml and 20ml syringe.  Needles, preferebly two each of 16’, 18’, 20’, 21’, 23’, and 26’,  Files for breaking the ampoule  Torniquets  Airway equipment  Ryles tube Drugs for Emergency Box:  Aminophylline 0.25 g/ml  Amylnitrite glass capsules for inhalation  Atropine sulphate 0.4mg/ml  Caffeine sodium benzoate 0.5g/2 ml.  Calcium Gluconate 1 g/10 ml vi.  Digoxin 0.25 mg/ml  Pentobarbitone 50mg/ml  Pentzocine VIGNAN PHARMACY COLLEGE,VADLAMUDI 13
  • 14. Role of PTC in Developing “Emergency Drug Lists”: (CONT) Supplies for Cabinet Utility Room  Venuous cannulation set.  Each set 12&17 venous catheters  Pieces 6’’shock blocks  Oxygen catheters  Sterile suction catheters  Razor with blades  Package sterile gelatine sponge  Resuscitation tube Other emergency supplies  Resuscitation carts  Phlebotomy sets  Oxygen equipments  Tracheotomy sets  Dextran and tubing  Burn sheets VIGNAN PHARMACY COLLEGE,VADLAMUDI 14
  • 15. Role of PTC in Drug Product Defect Reporting Programme:  The drugs purchased by hospital may be defective in quality. It is for the committee to get information about the defective drug products and to inform it first to the manufacturer for appropriate action.  If satisfactory answer is not obtained from the manufacturer or supplier, it should be reported to the Food and Drug Control Administration. VIGNAN PHARMACY COLLEGE,VADLAMUDI 15
  • 16. Role of PTC in Drug Utilization Review:  Drug utilization includes prescribing, dispensing, administering and ingesting of prescription of drugs. Hospital pharmacist should take medication history that should include following information.  Medication being taken at the time of admission, during admission, home remedies (OTC) drugs.  Drug-allergies and idiosyncrosy towards food products etc. VIGNAN PHARMACY COLLEGE,VADLAMUDI 16
  • 17. REFERENCE:  https://www.medicalcenter.virginia.edu/clinicalstaff/csec/pharmacy.html  https://www.ashp.org/-/media/assets/policy-guidelines/docs/guidelines/gdl- pharmacy-therapeutics-committee-formulary  https://en.wikipedia.org/wiki/Pharmacy_and_Therapeutics  https://www.blueshieldca.com/bsca/pharmacy/faqs/pharmacy-therapeutics- committee.sp VIGNAN PHARMACY COLLEGE,VADLAMUDI 17