The document provides a historical overview of the development of pharmacy as a profession from ancient times to the present. It discusses early medicine practices in ancient Egypt, Greece, Rome, the Arab world, and Renaissance Europe. Key developments included the establishment of the first pharmacy shops in Baghdad in the 8th century AD, the separation of pharmacy from medicine in the 13th century, and the founding of the first pharmacy schools and professional organizations in the 18th-19th centuries. The document then outlines the major eras and advances in pharmacy, from the industrialization and standardization of drugs in the 19th-20th centuries to current research areas like biotechnology and personalized medicine.
Historical background and development of profession of pharmacy: History of profession of Pharmacy in India in relation to pharmacy education, industry and organization, Pharmacy as a career, Pharmacopoeias: Introduction to IP, BP, USP and Extra Pharmacopoeia.
In ancient India the sources of drugs were of vegetable, animal and mineral origin.(Ayurveda).They were prepared empirically by few experienced persons. Knowledge of that medical system was usually kept secret within a family (Folkore).There were no scientific methods of standardization of drugs.
Historical Background and development of profession of pharmacy, History of profession of pharmacy in relation to Pharmacy Education, History of pharmacy in relation to Industry & Organization.
HISTORICAL BACKGROUND & DEVELOPMENT OF PROFESSION OF PHARMACYTeny Thomas
The following presentation deals with what the course of pharmacy is and what a pharmacist is. Also a short brief on the historical growth of the profession of pharmacy when related to education and industry is also discussed here. A detailed view on career in pharmacy is described lastly.
1. History Of Profession Of Pharmacy In India
It is the 1st Chapter under ER-2020 By PCI for Diploma in Pharmacy Students .
You can Increase Your Knowledge about the history of Pharmacy India . and also know about the history of India Health care systems with simple language
this ppt is used full all type of pharmacy students and faculty .
In this chapter we are learned
1.Definition Of Pharmaceutics
2.Scope Of Pharmaceutics
3.SCOPE AND POTENTIAL OF PHARMACY
4.History Of Profession Of Pharmacy In India
5.Drug Enquiry Committee
Historical background and development of profession of pharmacy: History of profession of Pharmacy in India in relation to pharmacy education, industry and organization, Pharmacy as a career, Pharmacopoeias: Introduction to IP, BP, USP and Extra Pharmacopoeia.
In ancient India the sources of drugs were of vegetable, animal and mineral origin.(Ayurveda).They were prepared empirically by few experienced persons. Knowledge of that medical system was usually kept secret within a family (Folkore).There were no scientific methods of standardization of drugs.
Historical Background and development of profession of pharmacy, History of profession of pharmacy in relation to Pharmacy Education, History of pharmacy in relation to Industry & Organization.
HISTORICAL BACKGROUND & DEVELOPMENT OF PROFESSION OF PHARMACYTeny Thomas
The following presentation deals with what the course of pharmacy is and what a pharmacist is. Also a short brief on the historical growth of the profession of pharmacy when related to education and industry is also discussed here. A detailed view on career in pharmacy is described lastly.
1. History Of Profession Of Pharmacy In India
It is the 1st Chapter under ER-2020 By PCI for Diploma in Pharmacy Students .
You can Increase Your Knowledge about the history of Pharmacy India . and also know about the history of India Health care systems with simple language
this ppt is used full all type of pharmacy students and faculty .
In this chapter we are learned
1.Definition Of Pharmaceutics
2.Scope Of Pharmaceutics
3.SCOPE AND POTENTIAL OF PHARMACY
4.History Of Profession Of Pharmacy In India
5.Drug Enquiry Committee
Historical background and development of profession of pharmacyRohit Kumar Trivedi
History and development of pharmacy profession
Historical background and development of profession of pharmacy
#rohitkumrtrivedi
B Pharma 1st semester pharmaceutics
Pharmacopoeia: the word derives from the ancient Greek word pharmakon means drug & poeia- to make.
It is a legally binding collection, prepared by a national or regional authority& contains list of medicinal substances, crude drug & formulas for making preparation from them.
it is GTU based syllabus chapter and all the points are covered like... handling of prescription , etc... very helpful for pharmacy students...and its in easy language..
Pharmaceutics is the area of study concerned with the formulation,
manufacturing stability and effectiveness of pharmaceutical dosage form. In
the previous unit various communicable, non-communicable disorders were
described. In this unit we will study how the drugs are administered in the body
to be effective. Drugs are rarely used alone. They are used as a part of a
formulation with other non-drug substances. These non-drug substances or
additives serve specific function. The drugs presented in the dosage form are
given in a specific quantity i.e. dose for a specific period. These dosage forms
are available in various forms as required for a specific disease condition.
Packaging of dosage form is another important aspect as the dosage form
should not degrade during storage. A good packaging is necessary to protect
the drug component from any type of deterioration till it reaches the consumer.
This presentation provide you the basic knowledge about the Pharmacopoeia and later about the Indian Pharmacopoeia. Details about the Indian Pharmacopoeia i.e Who publish it? When first edition was published? Published Addendum? Latest edition and its Addendum?
Career in pharmacy and scope of pharmacy. Pharma industry, Hospital pharmacy , Community Pharmacy, Teaching in Pharmacy, Sales & Marketing , Clinical research , Career in Regulatory Body, Biotechnology, Cosmetic, Food Industry etc.
Historical background and development of profession of pharmacyRohit Kumar Trivedi
History and development of pharmacy profession
Historical background and development of profession of pharmacy
#rohitkumrtrivedi
B Pharma 1st semester pharmaceutics
Pharmacopoeia: the word derives from the ancient Greek word pharmakon means drug & poeia- to make.
It is a legally binding collection, prepared by a national or regional authority& contains list of medicinal substances, crude drug & formulas for making preparation from them.
it is GTU based syllabus chapter and all the points are covered like... handling of prescription , etc... very helpful for pharmacy students...and its in easy language..
Pharmaceutics is the area of study concerned with the formulation,
manufacturing stability and effectiveness of pharmaceutical dosage form. In
the previous unit various communicable, non-communicable disorders were
described. In this unit we will study how the drugs are administered in the body
to be effective. Drugs are rarely used alone. They are used as a part of a
formulation with other non-drug substances. These non-drug substances or
additives serve specific function. The drugs presented in the dosage form are
given in a specific quantity i.e. dose for a specific period. These dosage forms
are available in various forms as required for a specific disease condition.
Packaging of dosage form is another important aspect as the dosage form
should not degrade during storage. A good packaging is necessary to protect
the drug component from any type of deterioration till it reaches the consumer.
This presentation provide you the basic knowledge about the Pharmacopoeia and later about the Indian Pharmacopoeia. Details about the Indian Pharmacopoeia i.e Who publish it? When first edition was published? Published Addendum? Latest edition and its Addendum?
Career in pharmacy and scope of pharmacy. Pharma industry, Hospital pharmacy , Community Pharmacy, Teaching in Pharmacy, Sales & Marketing , Clinical research , Career in Regulatory Body, Biotechnology, Cosmetic, Food Industry etc.
history of pharmacy, pharmacopoeia, british pharmacopoeia, ameracan pharmacopoeia, pharmaceutical codex, formularis, chemical professionals code of conduct.
We know how pharmacy is important. Pharmaceutices is the part of pharmacy. It is very essential for B.pharm & M. pharm students to know well about this topic. I am trying my best to present this topic, hopefully You will love this topic.
Pharmacy has been inseparable from mankind’s history. The history of preparation and use of medicines dates back to ancient times.
In ancient times, diseases were thought to be produced by evil forces or by a God’s anger.
Thus, religious persons (priests or shamans) or magicians were found to be associated with the treatment of patients. So called religious rituals always accompanied with the drug treatment.
Palestine last event orientationfvgnh .pptxRaedMohamed3
An EFL lesson about the current events in Palestine. It is intended to be for intermediate students who wish to increase their listening skills through a short lesson in power point.
Welcome to TechSoup New Member Orientation and Q&A (May 2024).pdfTechSoup
In this webinar you will learn how your organization can access TechSoup's wide variety of product discount and donation programs. From hardware to software, we'll give you a tour of the tools available to help your nonprofit with productivity, collaboration, financial management, donor tracking, security, and more.
Model Attribute Check Company Auto PropertyCeline George
In Odoo, the multi-company feature allows you to manage multiple companies within a single Odoo database instance. Each company can have its own configurations while still sharing common resources such as products, customers, and suppliers.
The French Revolution, which began in 1789, was a period of radical social and political upheaval in France. It marked the decline of absolute monarchies, the rise of secular and democratic republics, and the eventual rise of Napoleon Bonaparte. This revolutionary period is crucial in understanding the transition from feudalism to modernity in Europe.
For more information, visit-www.vavaclasses.com
Synthetic Fiber Construction in lab .pptxPavel ( NSTU)
Synthetic fiber production is a fascinating and complex field that blends chemistry, engineering, and environmental science. By understanding these aspects, students can gain a comprehensive view of synthetic fiber production, its impact on society and the environment, and the potential for future innovations. Synthetic fibers play a crucial role in modern society, impacting various aspects of daily life, industry, and the environment. ynthetic fibers are integral to modern life, offering a range of benefits from cost-effectiveness and versatility to innovative applications and performance characteristics. While they pose environmental challenges, ongoing research and development aim to create more sustainable and eco-friendly alternatives. Understanding the importance of synthetic fibers helps in appreciating their role in the economy, industry, and daily life, while also emphasizing the need for sustainable practices and innovation.
The Art Pastor's Guide to Sabbath | Steve ThomasonSteve Thomason
What is the purpose of the Sabbath Law in the Torah. It is interesting to compare how the context of the law shifts from Exodus to Deuteronomy. Who gets to rest, and why?
How to Split Bills in the Odoo 17 POS ModuleCeline George
Bills have a main role in point of sale procedure. It will help to track sales, handling payments and giving receipts to customers. Bill splitting also has an important role in POS. For example, If some friends come together for dinner and if they want to divide the bill then it is possible by POS bill splitting. This slide will show how to split bills in odoo 17 POS.
The Indian economy is classified into different sectors to simplify the analysis and understanding of economic activities. For Class 10, it's essential to grasp the sectors of the Indian economy, understand their characteristics, and recognize their importance. This guide will provide detailed notes on the Sectors of the Indian Economy Class 10, using specific long-tail keywords to enhance comprehension.
For more information, visit-www.vavaclasses.com
Sectors of the Indian Economy - Class 10 Study Notes pdf
Pharmaceutics I
1. IPS Academy College of Pharmacy, Indore (M.P.)
PHARMACEUTICS- I
UNIT-1
HISTORICAL BACKGROUND OF PHARMACY
DOSAGE FORM,PRESCRIPTION,POSOLOGY
By: POOJA TIWARI
ASSISTANT PROFESSOR
1
4. INTRODUCTION
4
•The word pharmacy is derived from Greek word
pharmakon meaning medicine or drug. Galen is the
father of Pharmacy.. Prof. William Procter is the father
of American Pharmacy .
•Pharmacy is the art and science of preparing and
dispensing drugs and medicines.
•It is a health profession.
•A shop or hospital dispensary where medicinal drugs
are prepared or sold.
6. INTRODUCTION
• Pharmacy as a profession and as a health care
discipline has gone through phenomenal changes and
development during the last few decades, at global as
well as regional levels.
• In the past, Pharmacists were known by names like
alchemists, apothecaries and compounders.
• Modern pharmacists are professionally qualified,
scientifically trained and technically competent health
care professionals knowing the secrets and facts of
drugs and medicines.
6
7. Pharmaceutics
Pharmaceutics is a branch of pharmacy which
includes the study of, formulation of drug in to a
dosage form. It is a systematic approach to get an
effective and stable formulation without disturbing its
quality. It is deal with technology involve in large
scale manufacturing.
Mahadeva Lal Schroff is considered as the father of
Pharmaceutics
7
8. HISTORY
Five Historical Periods
• Ancient Era: The beginning of time to 1600 AD
• Empiric Era: 1600 to 1940
• Industrialization Era: 1940 to 1970
• Patient Care Era: 1970 to present
• Biotechnology and genetic engineering: The new horizon
8
9. The Ancient Era
• Leaves, mud, and cool water were used to stop
bleeding and heal wounds
• Early man learned from watching injured animals’
behaviors
• Knowledge of materials with healing properties was
passed down through the tribes
• Medical information was documented on clay tablets
around 2600 BC
9
10. The Beginnings of Pharmacy
• The Ebers Papyrus, written around 1500 BC,
contained formulas for more than 800 remedies for
700 drugs.
• Herbs were the predominant form of curatives
10
11. The Greeks
• Hippocrates, the “father of medicine,” liberated
medicine from the belief that disease was caused by
spiritual reasons
• Theophrastus, the “father of botany,” classified plants
by their various parts
Mithridates studied the adverse effects of plants and
later became known as the “father of toxicology
11
12. The Romans
• The Romans organized medical and pharmaceutical
knowledge and converted theories into scientific rules
• The Romans, as well as the Greeks, were responsible
for preparing their own prescriptions
• The Romans initiated the first job titles of various
pharmacy-related personnel
12
13. Other Pioneers
• Dioscorides began the transition of the Greek system
of knowledge into the Roman system of science; he
is known as the “father of pharmacology”
• Galen, a Greek physician, wrote “On the Art of
Healing,” and was very critical of physicians who did
not prepare their own remedies
• Cosmos and Damien, the patron saints of pharmacy
and medicine, practiced both disciplines around 300
AD
13
14. Roman Pharmacy Titles
• Pharmacopeia — makers of remedies
• Pharmacotritae — drug grinders
• Unguentarii — makers of ointments
• Pigmentarii –— makers of cosmetics
• Pharmacopolae — sellers of drugs
• Aromatarii — dealers in spices
14
15. The Arabian Influence
• Formularies — continuation of documentation of
drug information
• Dosage forms — syrups
• Pharmacy shops — first appeared in Baghdad around
762 AD, and were privately owned
• Hospital pharmacies followed in Marrakech around
1190 AD
15
16. The Italian Influence
• Europe’s first university was established in Salerno,
and was responsible for major contributions to
pharmacy and medicine
• The Magna Carta of Pharmacy, separating pharmacy
from medicine, was issued by Emperor Frederick II
• Guilds of pharmacists were established
16
17. New Ideas
• A Swiss physician, Paracelsus, contradicted the
Galenic theories of botanical orientation to medicine
with his own theories based on chemicals
• Monasteries became host to their own pharmacies
• Germany became the first to governmentally regulate
its pharmacies
17
18. The Influence of Royalty
• Pharmacists who worked for royal families provided
specialized services, and were known as apothecaries
• New medicinal herbal substances, plants, trees, and
seeds began to be used
• Better documentation of this new knowledge began to
occur
18
19. The Renaissance
(Cultural rebirth that occurred in Europe)
• Pharmacy became separated from medicine
• Pharmacy regulation began
• University education of pharmacists was now
required
• Larger quantities of known and new drugs were
imported from the New World and the Orient
• New chemical medicines were introduced
19
20. The Empiric Era
• Pharmacopeias became the regulatory tools of
government, with standardized medicines listed
• Existing medications were questioned and tested as to
their actual effectiveness
• In the 18th century, pharmacy began to develop in the
colonies of the New World
• In 1751, Benjamin Franklin started the first hospital
in America .The first hospital pharmacist was
Jonathan Roberts
• William Proctor introduced control into the practice
of pharmacy in the New World
20
21. 19TH CENTURY
• In 19th century, pharmacy began a transformation
from an art to a science.
• Scientists began exploring the structure of drugs,
linking it to the activity of compounds, and they
began to synthesis compounds with similar structures.
• The mass production of drug products had started in
industry.
• New standards and new knowledge meant new
opportunities for precision in prescribing
compounding and dosing
21
22. Drugs Discovered in the
19th Century
• Quinine
• Caffeine
• Morphine
• Codeine
• Niacin
• Adrenalin
• Penicillin
• Phenobarbital
• Testosterone
22
23. The Patient Care Era
• Increased concentration on rational, targeted research
through the use of computers
• Increased number of available medicines
• Well-coordinated teams of scientists with other
professions such as statisticians and financial
managers
• Multiple drug therapy, however, led to adverse
reactions, interactions, and therapeutic outcomes that
were greater or less than desired
23
24. The New Horizon
• Research into gene therapy and genetic defects has
greatly increased
• Recombinant DNA technology is producing new
medications based on the patient’s genetic make-up
• Some medications that come from natural sources,
such as insulin, are prone to producing allergies
• Genetic research is involved in the pursuit of cures
for major diseases, such as cancer
24
25. 20TH CENTURY
• The 20th century will be forever remembered for its
remarkable advances in chemistry, medicine and
pharmacy.
• Countless new drugs were discovered and
manufacturers were literally at war to stay ahead with
new patents
25
26. EDUCATION
• Independent pharmacies were first established in Italy
and then countries like France and Germany.
• Pharmacy education at College/ University level
started in 1777 in France.
• Later in 1803 six schools of pharmacy were started in
France.
• Private pharmacy educational institutions arose in
Bavaria, the south east state in Germany in 1808.
• It was in 1821 the first American Pharmacy College –
Philadelphia College of Pharmacy admitted the first
batch of pharmacy students which was followed by
New York College of Pharmacy (1829). 26
27. Industry and Organization
It is a well-known fact that because of the British rule,
Pharmaceutical industry could not be develop
significantly in India. After independence, the
Government declared its industrial policy in the year
1950. The Government gave importance to the
development of the pharmaceutical industry During
1950, there were 65 domestic pharmaceutical units in
India,while foreign units were 28 in number. In 1952,
about 1,643 licenses were issued under the Drug Act.
In 1989, the number had increased to 12,000. Of these
27
28. continued..
only 1,554 were manufacturing units.In the year
2003-04, it had increased to over 24,000 units.In
1952, total investment in the pharmaceutical industry
was only Rs.24 crores which increased to Rs. 1,175
corers in 1984-85. Now, in 2004-05, it has reached
over Rs 15,000 crores. Due to development of the
pharmaceutical industry, the average life expectancy
of Indian increased from 32 years to 60 years. In fact,
India has also made adequate research in this field.
However, the multinationals have already entered the
Indian market. These companies are competing with
the Indian pharmaceutical companies.
28
29. continued..
In fact, India has also made adequate research in this
field. However,the multinationals have already entered
the Indian market. These companies are competing
with the Indian pharmaceutical companies. To give a
planned direction to all industries, the Republic of
India passed a bill known as the‘Industrial
Development Regulation Act’ in1951.
The Pharmaceutical industry is divided into two parts –
1.Bulk Drugs [fermentation, synthetic and plant
products]
29
30. continued..
2.Formulations- The whole pharmaceutical
manufacturing industry is divided into three
categories. Small scale, Medium scale, and Large
scale depending upon the amount of the investment.
Investments in the pharma industry were Rs.5,796
crores in the year 1994-95. The large-scale companies
are required to obtain industrial license from the
Director General of Technical Department.Presently,
the multinational companies operating in India are
keeping 40% of the shares with them and the rest
with the public.
30
31. continued..
All the pharmaceutical companies are governed by
the Drugs and Cosmetic Act, 1940 and the Rules of
1945 for the purpose of manufacturing, storage,
marketing, quality control, etc. Before starting the
manufacturing and marketing of the pharmaceutical
products, an industry is compelled to obtain license
from the Food and Drug Department. The food and
drug department is located in every part of the
country. In every state, there is a Commissioner or a
Director appointed by the Government.
31
32. continued..
Their major task is to enforce the existing rules and
regulations as well as the Bills passed by the
Parliament and the State Assemblies, from time to
time. In ancient days, medicinal and mineral herbs
were in practice,systematic drugs production took
place only by the 20th century.The modern
pharmaceutical industry came into existence in the
20th century with the invention of many active
medicinal compounds that could be efficiently
manufactured on a large scale.
32
33. continued..
In the process of research, new inventions have
replaced the old time herbal medicines. Since the
invention of Aspirin in 1899, the Indian
Pharmaceutical Industry has done remarkable
research work on life saving drugs.
33
34. CONCLUSION
• The face of pharmacy may have changed over the
past 1000 years, but its traditional role remains the
same.
• Although the preparation and preservation of drug
products have moved from pharmacy to the
pharmaceutical industry, the pharmacist continues to
fulfill the prescriber's intentions, by not only
dispensing a medication but also by providing a
quality product, providing advice and information,
and monitoring drug therapy.
34
36. 1. Before the Dawn of History
From beginnings as remote and simple as these came the proud profession of
Pharmacy. Its development parallels that of man. Ancient man learned from instinct,
from observation of birds and beasts. Cool water, a leaf, dirt, or mud was his first
soothing application. By trial, he learned which served him best. Eventually, he
applied his knowledge for the benefit of others..
36
37. 2. Pharmacy in Ancient China
Chinese Pharmacy, investigated the medicinal value of several hundred herbs and
Medicinal plants .
37
38. 3. Days of the Papyrus Ebers
Though Egyptian medicine dates from about 2900 B.C., best known and most
important pharmaceutical record is the "Papyrus Ebers" (1500 B.C.), a collection of
800 prescriptions, mentioning 700 drugs.
38
39. 4. Theophrastus–FatherofBotany
Theophrastus (about 300 B.C.), among the greatest early Greek philosophers and
natural scientists, is called the "father of botany.". He lectured to groups of
students.
39
40. 5. Galen Experimenter in Drug Compounding
He was the originator of the formula for a cold cream, essentially similar to
that known today. Many procedures Galen originated have their counterparts
in today's modern compounding laboratories.
40
41. 06. The First Apothecary Shops
The Arabs separated the arts of apothecary and physician, establishing in Bagdad late
in the eighth century the first privately owned drug stores.
41
42. 07. Separation of Pharmacy
In the 17th century Emperor of Germany at his palace in Palermo, he presented
subject Pharmacists with the first European edict completely separating their
responsibilities from those of Medicine, and prescribing regulations for their
professional practice.
42
43. 08. The First Official Pharmacopeia
The idea of a pharmacopoeia with official status, to be followed by all apothecaries,
originally written in Italian, was published and became the legal standard for the
city-state in 1498.
43
44. 09. American Pharmacy Builds its Foundations
The Philadelphia College of Pharmacy; a school of pharmacy; first pharmaceutical
association in the United States; American Pharmacy's first educational institution.
44
45. 10. The Pharmacopeia Comes of Age
The first "United States Pharmacopoeia" (1820) was the work of the medical
profession. It was the first book of drug standards .
45
46. 11. The Standardization of Pharmaceuticals
Despite the professional skill and integrity of 19th-century pharmacists.
46
47. 12. Pharmaceutical Manufacturing Comes of Age
Pharmaceutical manufacturing as an industry apart from retail Pharmacy had its
beginnings about 1600; really got under way in the middle 1700's. It developed
first in Germany, then in England and in France.
47
48. 13. Pharmacy Today and Tomorrow
Pharmacy, great professions. Like Medicine, it has come through many revolutions,
has learned many things, has had to discard many of its older ways. Pharmacists are
among the community's finest educated people. When today's retail pharmacist fills
a prescription written by a physician, he provides a professional service
incorporating the benefits of the work of pharmacists in all branches of the
profession - education, research, development, standards, production, and
distribution. Pharmacy's professional will continue to grow in the future.
48
56. 56
Pharma Industry
R & D Production Marketing
Formulation Tablet Sales Promotion
Quality Assurance Capsule Sales executive
Quality Control Injections Product development
Bioanalytical Manager
Biotechnology
Pharmacology
Drug Discovery
Technology Transfer
57. 57
Key role as community pharmacist
Evaluates a patient's drug-related needs
● Determine whether the patient has any actual or potential
drug related problems.
● Works with the patient and other healthcare professionals
to design, implement and monitor a therapeutic plan that
will resolve/prevent the problem.
58. 58
PHARMACIST IN GOVERNMENT SERVICE
Pharmacist in Army, Navy, Air force & Govt.
Hospitals
Drug Inspectors –Govt of INDIA and State level
Scientists- Food and Drugs
Govt.University Proffesors and HODs
Opportunity to be Selected in UPSC and State
Public Service Commissions.
Government Analysts and Forensic Scientists
Research on tropical diseases, Public health
Govt.Certified Pharmacologist &Toxicologist
59. PHARMACIST IN GOVERNMENT SERVICE
59
Govt. Approved Chemist
Consultants ( Mental health,Addiction, family
planning, poisons, self-medication, immunization
61. Pharmacopoeia
• Derived from Greek word ‘Pharmakon’ means drug
and ‘Poiea’ means to make.
• It is a legal and official book issued by recognized
authorities usually appointed by Government of each
country.
• It comprises list of pharmaceutical substances, formulae
along with their description and standards.
61
62. Indian Pharmacopoeia
• It is written in English & official titles of monographs given in
Latin.
• Indian Pharmacopeia committee under chairmanship of Dr. B. N.
Ghosh Published first edition of IP in 1955.
• It covers 986 monographs
• Second edition of IP was published in 1966 under the
chairmanship of Dr. B. Mukkerji.
• Official titles of monographs given in English.
• Dose were expressed in Metric system.
• For Tablets and Injections “USUAL STRENGTH” have been
given.
• Formulations of the drugs were given immediately after the
monograph of drugs.
62
63. Continued…
63
•93 new monographs were added.
•Supplement to this edition was published in 1975.
•126 new monographs have been included & 250 monographs
have been amended.
•Third edition of IP was published in 1985 with two volumes
•261 new monographs have been added.
•450 monographs were deleted.
• Addendum I to IP was published in 1989 were 46 new
monographs added and 126 amended.
• Addendum II was published in 1991 were 62 new monographs
added and 110 amended
64. Continued…
64
•Fourth edition of IP was published in 1996 under the
chairmanship of Dr. Nityanand.
•It has been made effective from 1st December 1996.
• It covered 1149 monographs and 123 appendices.
• It includes 294 new monographs & 110 monographs have
been deleted.
•Addendum I has been made effective from 31st December 2000
were 42 new monographs have been added.
• Addendum II has been made effective from 30th June 2003
were 19 new monographs have been added.
•The veterinary supplement to IP 1996 contains 208 monographs
65. Continued…
65
•Fifth edition of IP was published in 2007 & addendum to this
edition was published in 2008.
•IP 2007 is presented in Three Volumes.
•Volume One contains general notices & general chapters.
• Volume Two & Three contains general monographs on drug
substances , dosage forms & Pharmaceutical aids.
• 6th edition of IP is published in 2010.
• The 6th edition of the Indian Pharmacopoeia 2010 is published by
the Indian Pharmacopoeia Commission (IPC) Ghaziabad
66. Continued…
66
•This edition would be effective from 1st September, 2010.
• The Indian Pharmacopoeia 2010 is presented in three volumes
•Volume I contains the Notices, Preface, the Structure of the
•IPC, Acknowledgements, Introduction, and the General Chapters.
•Volume II contains the General Notice, General Monographs
on Dosage Forms and Monographs on drug substances, dosage
forms and pharmaceutical aids (A to M).
•Volume III contains Monographs on drug substances,dosage
forms and pharmaceutical aids (N to Z). Followed by Monographs
on Vaccines and Immunosera for Human use, Herbs and Herbal
products, Blood and blood related products, Biotechnology
products and Veterinary products.
67. 67
•The scope of the Pharmacopoeia has been extended to include
products of biotechnology, indigenous herbs and herbal products,
veterinary vaccines and additional antiretroviral drugs and
formulations, inclusive of commonly used fixed-dose
combinations. Standards for new drugs and drugs used under
National Health Programmes are added and the drugs as well as
their formulations not in use now a day are omitted from this
edition.
•The number of monographs of Excipients, Anticancer drugs,
Herbal products and antiretroviral drugs has been increased in
this edition.
Continued…
68. Continued…
68
•Monographs of Vaccines and Immunosera are also upgraded in
view of development of latest technology in the field.
•A new chapter on Liposomal products and a monograph of
Liposomal Amphotericin B injection is an added advantage in
view of latest technology adopted for drug delivery.
• A chapter on NMR is incorporated in Appendices.
•The chapter on microbial contamination is also updated to a
great extent to harmonise with prevailing international
requirements.
69. Continued…
69
•The seventh edition of the Indian Pharmacopoeia (IP 2014) is
published by the Indian Pharmacopoeia Commission (IPC) on
behalf of the Government of India, Ministry of Health & Family
Welfare.
• The Indian Pharmacopoeia 2014 is presented in four volumes.
The scope of the Pharmacopoeia has been extended to include
additional anticancer drugs & antiretroviral drugs and
formulations, products of biotechnology, indigenous herbs and
herbal products, veterinary vaccines.
• The IP 2014 incorporates 2550 monographs of drugs out of
which 577 are new monographs consisting of APIs, excipients,
dosage forms and herbal products etc.
70. Continued…
70
• list of 577 New Monographs not included in IP-2010 and its
Addendum-2012 but added in this edition containing 313 New
Monographs on drug substances, Dosage forms & Pharmaceutical
aids (A to Z), 43 New Drugs Substances Monographs, 10
Antibiotic Monographs, 31 Herbal Monographs, 05 Vaccines &
immunosera for human use, 06 Insulin Products, 07
Biotechnology Products etc. along with the 19 new General
Chapters.
• 19 New Radiopharmaceutical Monographs & 1 General chapter
is first time being included in this edition.
• This edition of Indian Pharmacopoeia-2014 is now under
printing and will be available to stakeholders probably in
Sept.2013, before three months of its effective date, i.e. 1st Jan.
2014.
71. IP 2018
71
The Eighth edition of Indian Pharmacopoeia (IP- 2018) is
published by the Indian Pharmacopoeia Commission (IPC) on
behalf of the Ministry of Health & Family Welfare, Government
of India.
Indian Pharmacopoeia 2018 Salient Features:
Incorporating with 4 volume
New Monographs : 220
170 New Chemical Monographs
49 API
64 Formulations
53 Fixed Dose Formulations
02 Excipients
02 Antibiotic
72. Continued..
72
15 New Herbs and Herbal Products Monographs
03 New Radiopharmaceutical Monographs
14 New Veterinary Non-Biological Monographs
18 New Biological Monographs :
02 Vaccines & Immunosera for Human Use
06 Biotechnology Derived Therapeutic Products
10 Blood and Blood Related Products
73. Continued..
73
Standards for New Drugs, Drugs under National Health
Programme & Drugs in National List of Essential Medicines have
been included.
For ease of access and to make Pharmacopoeia more user friendly
index has been incorporated in Volume 1 along with that already
existing in Volume IV of IP
75. British Pharmacopoeia
• First edition of BP was published in 1864.
• It consist of two sections
• Part I:- Materia Medica & Part II:- Preparation & compounds.
• In this edition titles of drugs & preparations were in English
instead of Latin and metric system. Fourth edition of BP was
published in 1898.
• Fifth edition of BP was published in 1914.
• Eighth edition of BP was published in 1953.
• It has been published annually.
• In BP 2007 monographs has been introduced for material
specifically used in preparation of Traditional Chinese medicines
• BP 2008 contains approximately 3100 monographs for substances,
preparations and articles used in practice
75
77. UNITED STATE PHHARMACOPEIA
77
• First edition of United state Pharmacopeia was
published on 15th December 1820 in both Latin &
English.
• From 1820 to 1942 it was published at Ten years
intervals.
• From 1942 to 2000 it was published at Five years
intervals.
• From 2002 it was published annually. First National
Formulary of the united state appeared in 1888.
78. UNITED STATE PHHARMACOPEIA
78
•USP21-NF16 have eight supplements.
•First appeared in January 1985 & last in November
1988.
•USP22-NF17, 1990 is the third revision that
consolidates USP & NF into a single volume.
• Electronic version of USP-NF on floppy disks was
introduced in 1992.
•USP23-NF18, was published in Mumbai as an Asian
edition at the end of 1994.
79. UNITED STATE PHHARMACOPEIA
79
•USP23 has ten supplements.
• First supplement was published in January 1995 & Last
in May 1999.
•USP24-NF19, appeared from first January 2000.
• USP30-NF25, appeared from May 2007.
• It contains Scientific standards for drugs, dietary
substances, biological products & Excipients used in
dosage forms.
•It contains 4,100 monographs and 200 general chapters.
• It has been printed in three volume set.
80. UNITED STATE PHHARMACOPEIA
80
• Volume I contains general chapters & Volume II & III
contains monographs.
•First supplement to USP30-NF25, appeared from
August 2007 & second supplement from November
2007 which will be considered official from May 2008.
•From 2006, Spanish edition of USP is also being
published.
•Current edition of USP 2014 is in process.
81. European Pharmacopeia
• European pharmacopeia commission started working since 1964
to prepare EP
Editions
• 1st edition: published 1967
• 2nd edition: published 1980
• 3rd edition: published 1997
• 4th edition: published 2001, valid from 1 January 2002
• 5th edition: published 15 June 2004, valid from 1 January 2005
• 6th edition: published 16 July 2007, valid from 1 January 2008
• 7th edition: published June 2010, valid from 1 January 2011
• 8th edition: published June 2013, valid from 1 January 2014
• 9th edition: published June 2017
81
88. continued..
88
Tablets:-
They are unit solid dosage forms
consisting of active ingredient and suitable
pharmaceutical excipients.
They may vary in size, shape, weight,
hardness, thickness, disintegration and
dissolution characteristics, and in other
aspects.
89. Capsules:-
• They are unit solid
dosage forms consisting
gelatin shell that breaks
open after the capsule
has been swallowed and
releasing the drug.
• Types-
• hard-shell gelatin capsule
• soft-shell gelatin capsule
89
90. continued..
1 . soft gelatin shell manufactured
in one piece with drug usually in
liquid form inside the shell, e.g.
fat-soluble vitamins A and E
2. hard shell manufactured in two
pieces that fit together and hold the
drug, either in powdered or
granular form.
90
91. continued..
Powder:-
• They are bulk solid
dosage forms consisting
two or more medicament
meant for internal or
external use.
• Size of the powder
determine the
effectiveness of
physiological properties.
91
92. 92
Granules :The bitter, nauseous and
unpleasant powders cannot be given in the tablet form or
in a capsule because a large number of them are required
to be taken as a single dose.
Examples
Proergy - protein granules
Promer plus - vitamins granules
Promiz - mineral and hematinic granules
94. continued..
• Semisolids contain both liquids and solids .They are meant
for topical application.
1.External application:
• Creams: -
• Creams are viscous semi-solid emulsions, that is used for
external application that is mixtures of oil and water.
• They usually contain a water soluble base due to which they
can be easily removed.
• They are divided into two types-
• 1.O/W TYPE
• 2.W/O TYPE
94
95. 95
Ointment : is a topical medication applied on the body
surfaces. In medical terms, an ointment is defines as a
homogeneous, viscous, semi-solid preparation with a high
viscosity, that is used for external application. An
ointment has medicated ingredients which serve a
protective, therapeutic, or prophylactic purpose when
applied on the skin or mucous membranes .
Pastes :a soft plastic mixture or composition; especially
an external medicament that has a stiffer consistency than
an ointment and is less greasy because of its higher
percentage of powdered ingredients.
96. 96
Jellies: are transparent or translucent, non greasy, semi
solid preparations mainly used for the external
application to the skin.eg. Ephedrine sulphate jelly
Internal application
suppository: is a drug delivery system that is inserted
into the rectum (rectal suppository), vagina (vaginal
suppository) or urethra (urethral suppository), were it
97. 97
dissolves or melts and is absorbed into the blood stream.
They are used to deliver both systemically and locally
acting medications.
Examples
Dulcolax - Bisacodyl suppositories
99. Monophasic liquid dosage form
99
•Monophasic dosage form refers to liquid preparation
containing two or more components in one phase
system, it is represent by true solution.
•A true solution is a clear homogenous mixture that is
prepared by dissolving solute in a suitable solvent
•The component of the solution which is present in a
large quantity is known as “SOLVENT” where as the
component present in small quantity is termed as
“SOLUTE”.
100. Liquids meant for internal
administrations
100
Syrup : Aqueous preparations of 60% to 85% sucrose
with or without flavoring agents and medicinal
substances. e.g. Chlorpheniramine maleate syrup, Chloral
hydrate .
•Elixirs : Clear, aromatic, sweetened hydro alcoholic
solutions with or without medicinal substances, intended
for oral use. Eg: Dexamethasone elixir .
•Linctuses : Viscous, liquid and oral preparations that are
generally prescribed for the relief of cough. Eg: Codeine
Linctus.(expactorant )
101. Liquids used in the mouth
101
Gargles :Aqueous solutions containing antiseptics or
antibiotics used to treat throat infections. Available in
concentrated form with direction for dilution with warm
water before use. eg: Povidone Iodine gargle.
• Mouthwash: Aqueous solution with a pleasant taste and
odor used to clean and deodorize the buccal cavity. Have
antiseptic and astringent activity.eg: Antiseptics-phenol
derivatives.
• Throat paints : Viscous liquid preparation used for
mouth and throat infections. Eg: Phenol glycerine,
Compound Iodine
102. Liquids instill into body cavity
102
•Eye drops: Sterile, aqueous/oily solutions intended for
instillation in eye. Eg: Timolol maleate eye drops.
• Nasal drops: Administered through the nose to obtain
local effect. Used during nasal congestion and upper-
respiratory tract problem. Eg: Oxymetazolin Hydrochloride
nasal drops.
• Enemas: Aqueous or oily solution that is introduced into
the rectum and colon via the anus for cleansing, therapeutic
or diagnostic purposes.
103. Liquid meant for skin
103
•Liniments : Oily liquid preparations, intended for
external application with rubbing action to the affected
area. Use to relief pain and stiffness, such as from
muscles spasm and arthritis.
•Lotions : Topical preparation with a low to medium
viscosity. Use to moisturize dry skin. Eg: Calamine
Lotion, baby lotion
•Paints : Solutions used to sterilize the skin. Eg.
Betadine antiseptic paint, Magenta paint
104. Biphasic liquid dosage form
104
The liquid which consist of two phases are known
as biphasic liquids e.g. emulsion and suspensions
105. Prescription
It’s written order, especially by a physician, for the
preparation and administration of a medicine or
other treatment.
105
107. Parts of prescription
1. Date
2. Name, Age, Sex and Address of the patient.
3. Superscription (Rx)
4. Inscription
5. Subscription
6. Signatura
7. Renewal Instructions
8. Name, Signature & Registration no. of registered
physician
107
108. Date
It helps the pharmacist to find out the date of prescribing and the date
of prescription for filling. It also helps
-To know when the medicines were last dispensed
-To prevent the misuse of the drug by the patients.
The prescription which prescribes narcotic or other habit forming
drugs must bear the date so as to avoid the misuse of the
prescription.
Name, age, sex and address of the patient
Name, age, sex and address of the patient must be written in the
prescription because it serves to identify the prescription. Age and
sex of the patient especially the children, help the pharmacist to
check the prescribed dose of the medicine.
108
109. Inscription
This is the main part of the prescription, contains the names and
quantities of the prescribed ingredients
The names of the ingredients are generally written in English but
common abbreviation used can be written both in English and Latin
language. Extreme care should be taken by the pharmacist during
interpreting the abbreviations otherwise can lead to serious errors.
Subscription Subscription provides the direction to the pharmacist for
the preparation of the prescription information and the quantity and
dosage form of the drug to be dispensed.
109
110. Sugnatura
This consists of the direction to be given to the patient
regarding the administration of the drugs.
The instruction may include
• The quantity to be taken or the amount to be used.
• The frequency and timing of drug administration
• The route of drug administration
• The special instruction such as dilution direction.
110
111. 111
Renewal instruction
The prescriber indicates on every prescription,
whether it may be renewed and if so how many times.
It is particularly important for the prescriptions
containing the narcotic and other habit forming drugs
to prevent its misuse.
Name, signature, address & registration no. of the
prescriber
The prescription must bear the signature of the
prescriber along with the registration number and
address.
114. Receiving the Prescription
114
Pharmacist should himself receive the Prescription.
It includes:
1.Reading the prescription:-
Prescription should be completely and carefully read
from top to bottom.
2.Checking of prescription:-
Prescription should be checked for any
incompatibility
117. Continued…
117
Packaging
After compounding packaging of prescription
should be done.
For packaging following containers are used
1.Round vials
2.Oval bottles
3.Wide mouth bottles
4.Colored bottles
4.Collapsible tubes
5.Paper wrappers
6.Dropper bottles
118. Continued…
118
Labeling:
The filled container should be suitably labeled.
The label should be affixed on smooth surface of
bottle.
Label information's
Type of prescription
Name, age & sex of patient
Date of dispensing
Storage condition
Name & address of pharmacy
In case of liquid preparation attachauxiliary label
Route of administration
119. Continued…
119
Rechecking
Each prescription should be rechecked After
labeling container should be thoroughly polished
to remove finger prints
Recording
A variety of prescription files are available
which serve to maintain and preserve original
prescription in numerical order
120. Pricing of Prescription
120
The prescription should be priced immediately
after receiving it & informed the patient about
it. This should be done before starting the
compounding to avoid any dispute
122. Sources of errors in prescription
Following are the sources of errors which arise in
prescription:
1) Abbreviation: Abbreviation presents a problem in
understanding parts of the prescription order. Extreme
care should be taken by a pharmacist in interpreting the
abbreviation. Acromycin-Acro-Acrostatin
2) Name of the Drug: There are certain drugs whose
name look or sound like those of other drugs. Some of the
examples of such drugs are as under:
Examples of Drugs often Confused
Digitoxin- Digoxin
Prednisone -Prednisolone
123. Continued…
Name of the pharmaceutical products have been
changed on certain occasion due to the possible
confusion with the name of the other products, e.g., the
name of potassium supplement was changed from
Kalyum to Kolyum because of the possible confusion
of the former designation with valium.
3) Strength of the Preparation: The strength of the
preparation should be stated by the prescriber For
example, it will be a wrong decision on the part of a
pharmacist to dispense paracetamol tablet 500 mg
124. Continued…
when prescription for paracetamol tablet is received with
no specific strength.
4)Dosage Form of the Drug Prescribed: Many
medicines are available in more than one dosage form. For
example, liquid, tablet, capsule and suppository. The
pharmaceutical form of the product should be written on
the prescription in order to avoid ambiguity.
125. Continued…
5) Dose: Unusually high or low doses should be discussed
with the prescriber. For example, a prescription for
sustained release formulation to be administered after
every four hours should be thoroughly checked because
such dosage forms are usually administered only two or
three times a day.
6) Instructions for the Patient: The quantity of the drug
to be taken, the frequency and timing of administration,
and route of administration should be clearly given in the
prescription so as to avoid any confusion.
126. Continued…
126
7) Incompatibilities: It is essential to check that there are
no pharmaceutical or therapeutic incompatibilities in a
prescribed preparation and that different medicines
prescribed for the same patient do not interact with each
other to produce any harm to the patient.Certain Antibiotic
should not be given with meals since it is significantly
decrese the absorption of given drug.
128. Posology
128
The word posology is derived from the Greek word
posos means how much and logos means science.
So we can define posology as a branch of medical science
which deals with dose or quantity of the drug .
129. factors affecting posology
• These are many factors are:
• Age
• Body weight
• Gender
• Route of administration
• Time of administration
• Presence of diseases
129
132. Continued…
132
1.AGE: The pharmacokinetics of many drugs changes with
age. So while determining the dose of a drug, the age of an
individual is of great significance. Children and old people
need lesser amount of drug than the normal adult dose,
because they are unable to excrete drugs to that extent as
adults. Children can tolerate relatively larger amounts of
belladonna, digitalis and ethanol whereas, elderly patients
are more sensitive to some Drug effects e.g. hypnotics and
tranquillizers which may produce confusion states in them.
133. Continued…
133
2.SEX: Women do not always respond to the action of
drugs in the same manner as it is done in men. Morphine
and barbiturates may produce more excitement before
sedation in women. Special care should be taken when
drugs are administered during menstruation, pregnancy
and lactation. The strong purgatives such as aloes should
be avoided during menstruation. Similarly the drugs which
may stimulate the uterine smooth muscle e.g. drastic
purgatives, antimalarial drugs and ergot alkaloids are
contra indicated during pregnancy
134. Continued…
134
There are certain drugs which on administration t the
mother are capable of crossing the placenta and affecting
the foetus e.g. alcohol, barbiturates, narcotic and non
narcotic analgesics etc. During lactation, the drugs like
antihistamines, morphine and tetracycline which are
excreted in milk should be avoided or given very
cautiously to the mothers who are breast feeding to the
babies.
3.BODY WEIGHT: The average dose is mentioned either
in terms of mg per Kg weight or as a total single dose for
an adult weighing between 50-100 Kg.
135. Continued…
135
However, the dose expressed in this fashion may not apply
in case of obese patients, children and malnourished
patients. It should be calculated according to Body Weight
4.ROUTE OF ADMINISTRATION: Intravenous doses of
drugs are usually smaller than the oral doses, because the
drugs administered intravenously enter the blood stream
directly. Due to this reason the onset of drug action is quick
with intravenous route and this might enhance the chances
of drug toxicity. The effectiveness controlled by the route of
administration.
136. Continued…
136
5.TIME OF ADMINISTRATION: The presence of food
in the stomach delays the absorption of drugs. The drugs
are more rapidy absorbed from the empty stomach. So the
amount of drug which is very effective when taken before
a meal may during or after meals. The irritating drugs are
better tolerated if administered after meals e.g. iron,
arsenic and cod-liver oil should always be given after
meals.
6.ENVIRONMENTAL FACTORS: Daylight is stimulant,
enhancing the effect of stimulating drugs and diminishing
the effect of hypnotics.
137. Continued…
137
Darkness is sedative. Hypnotics are more effective at night.
The amount of barbiturate required to produce sleep during
daytime is much higher than the dose required to produce
sleep at night. Alcohol is better tolerated in cold
environments than in summer.
7.EMOTIONAL FACTORS: The personality and
behaviour of a physician may influence the Effect of drug
especially the drugs which are intended for use in a
psychosomatic disorder. The females are more emotional
than males and requires less dose of certain drugs.
138. Continued…
138
Inert dosage forms called placebos which resemble the
actual medicament in the physical properties are known
to produce therapeutic benefit in diseases like angina
pectoris and bronchial asthma.
8.PRESENCE OF DISEASE: Drugs like barbiturates and
chlorpromazine may produce unusually prolonged effect
in patients having liver cirrhosis. Streptomycin is
excreted mainly by the kidney may prove toxic if the
kidney of the patient is not working properly. During
fever a patient can tolerate high doses of antipyretics than
a normal person.
139. Continued…
139
9.ACCUMULATION: The drugs which are slowly
excreted may built up a sufficient high concentration in the
body and produce toxic symptoms if it is repeatedly
administered for a long time e.g. digitalis, emetine and
heavy metals. This occurs due to accumulative effect of the
drug. The cumulative effects are usually produced by slow
excretion, degradation and rapid absorption of drugs.
Sometimes, a cumulative effect is desired in drugs like
phenobarbitone in the treatment of epilepsy.
140. Continued…
140
10.SYNERGISM:When two or more drugs are used in the
combination form, their action is increased. The
phenomena is called synergism. Synergism is very useful
when desired therapeutic result needed is difficult to
achieve with a single drug e.g. procaine and adrenaline
combination, increases the duration of action of procain.
11.ADDITIVE EFFECT: When the total pharmacological
action of two or more drugs administered together is
equivalent to sum of their individual pharmacological
action, the phenomena is called as an additive effect.
141. Continued…
141
For example, combination of ephedrine and aminophylline
in the treatment of bronchial asthma.
12.ANTAGONISM: When the action of one drug is
opposed by the other drug on the same physiological system
is known as drug antagonism. The use of antagonistic
responses to drugs is valuable in the treatment of poisoning
e.g. milk of magnesia is given in acid poisoning where
alkaline effect of milk of magnesia neutralize the effect of
acid poisoning. When adrenaline and acetylcholine are
given together they neutralise the effect of each other
142. Continued…
142
due to antagonism because adrenaline is vasoconstrictor and
acetylcholine is vasodilator.
13.IDIOSYNCRASY: An extraordinary response to a drug
which is different from its characteristic pharmacological
action is called idiosyncrasy. The word idiosyncrasy has
now been replaced by the term drug allergy. For example,
small quantity of aspirin may cause gastric haemorrhage and
a small dose of quinine may produce ringing in the ears.
Some persons are sensitive to penicillin and sulphonamide
because they produce severe toxic symptoms.
143. Continued…
143
14.TOLERANCE: When an unusually large dose of a drug
is required to elicit an effect ordinarily produced by the
normal therapeutic dose of the drug, the phenomena is
termed as drug tolerance. e.g., smokers can tolerate
nicotine, alcoholic can tolerate large quantity of alcohol.
The drug tolerance is of two types:-
(i) True tolerance, which is produced by oral and parentral
administration of the drug.
(ii) (ii) Pseudo tolerance, which is produced only to the
oral route of administration.
144. Continued…
144
15.TACHYPHYLAXIS: It has been observed that when
certain drugs are administered repeatedly at short
intervals, the cell receptors get blocked up and
pharmacological response to that particular drug is
decreased. The decreased response cannot be reversed by
increasing the dose. This phenomenon is known as
tachyphylaxis or acute tolerance. For example, ephedrine
when given in repeated doses at short intervals in the
treatment of bronchial asthma may produce very less
response due to tachyphylaxis. Similarly, drugs like
amphetamine, cocaine and nitrates behave in this way.
145. Continued…
145
16.METABOLIC DISTURBANCES: Changes in water
electrolyte balance and acid base balance, body temperature
and other physiological factor may modify the effects of
drugs. Salicylates reduce body temperature only in case an
individual has rise in body temperature. They have no
antipyretic effect if the body temperature is normal. The
absorption of iron from G.I.T. is maximum if the individual
has an iron deficiency anaemia.
147. Continued…
147
1.DOSES PROPORTIONATE TO AGE
(i) YOUNG’S FORMULA:
Dose for the child= (Age in years/Age in years+12)x Adult
dose
The formula for calculating the doses for children under 12
years of age.
(ii) DILLING’S FORMULA: Dose for the child= (Age in
years/20)x Adult dose The formula is used for
calculating the doses for children in between 4 to 20
years of age.
148. Continued…
148
2.DOSES PROPORTIONATE TO BODY WEIGHT:
Clark’s formula is used to calculate the dose for the child
according to body weight.
CLARK’S FORMULA:
Dose for the child= (Child’s weight in Kg/70)x Adult
dose
149. Continued…
149
3.DOSES PROPORTIONATE TO SURFACE AREA: The
calculation of child dose according to surface area is
satisfactory and appropriate rather than the method based
on age. The method is more complicated than the method
based on age. The method is based on the following
formula:- Percentage of adult dose = (Surface area of
child/Surface area of adult)X 100
The body surface area is calculated from the height and
weight of the child. It is better to depend on a handy
reference book rather than on one’s memory while
prescribing a dose for a child.