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Peripheral Nerve Injuries
Dr.Ashutosh Kumar
AP, Dept. of Orthopaedics
RMCH, Bareilly
Introduction
• Peripheral nerve damage affecting the upper and lower extremities can vary widely
in cause and extent. E.g. stretching, compression and transection.
• Many disorders, ranging from mild carpal tunnel syndrome to severe brachial
plexopathy, need to be considered in a patient presenting with pain, sensory loss, or
weakness involving the shoulder, arm, or hand.
Nerve injuries: Acute injury
: Chronic injury
Mechanism of injury:
• Crush/compression
• Strech/Traction
• Laceration/Transection
• Metabolic disturbances
• Ischaemia
• Radiation
• Electrical injury
• Thermal injury
•
SystemicDiseases
InfectiousCauses
• & Idiopathic
Entrapment Syndromes
Common nerve injuries
Upper limb
• Axillary nerve injury
• Radial nerve injury
• Median nerve injury
• Ulnar nerve injury
Lower limb
• Femoral nerve injury
• Sciatic nerve injury
• Peroneal nerve injury
Primary injury
– Results from same trauma that injures a bone or joint
– Radial nerve is the most commonly injured. Of humeral
shaft fractures, 14 % is complicated by radial nerve injuries
– Displaced osseous fragments
– Stretching
– Manipulation
Secondary injury
– Results from involvement of nerve by infection, scar, callous or
vascular complications which may be hematoma, AVfistula,
Ischemia or aneurysm
Diagnosis of Peripheral nerve injuries
• History
– Which nerve ?
– What level ?
– What is the cause ?
– What degree of injury ?
– Old or fresh injury ?
Diagnosis of Peripheral nerve inuries
1. Motor:
– All muscles distal to the injury – paralyzed &
atonic
–
–
Atrophy : 50 -70 % in 1sttwomonths
Striations & motor end plate configurations
retained for 12 – 18 months (critical limit of
delay)
2. Sensory :
• Sensory loss usually follows a definite
anatomical pattern, although factor of
overlap from adjacent nerves may be
present
• Autonomous zone
• Tinel’s sign
(3) Reflex
• Abolishes all reflexes transmitted by that
nerve, either afferent or efferent arc.
• Complete & incomplete lesion. So , not a
reliable guide to injury severity.
(4) Autonomic:
• Loss of sweating
• Loss of pilomotor response and
• Vasomotor paralysis in autonomous zone
(5) Others:
• Trophic Changes
•
•
Esp. hand and feet
Skin – thin, glistening, breaks easily to form
ulcers that heal slowly
• Fingernails
• Ridged, distorted and brittle
• Osteoporosis (Reflex sympathetic dystrophy)
Classification of nerve injuries
Seddon Classification
1. Neuropraxia:
1. Minor contusion or compression with preservation of axis – cylinder of
myelin sheath.
2. Impulse transmission physiologically interrupted.
3. Complete recovery in a few days toweeks
2. Axonotemesis :
1.More significant injury
2.Breakdown of axon and distal Wallerian degeneration butwith
preservation of schwann cell & endoneurial tubes
3.Spontaneous regeneration with good functional recovery canbe
expected
3.Neurotmesis
1.More severe injury
2.Complete anatomical severance, avulsion or crushing of nerve
3.Axon, Schwann cell & endoneurial tubes are
completely disrupted
4.Spontaneous recovery cannot be expected unlessexplored
Sunderland
Classification


Each degree of injury suggesting a greater anatomical
disruption with its correspondingly altered prognosis
Anatomically various degrees (1st – 5th) representinjury
to





Myelin
Axon
Endoneurial tube & it’scontent
Perineurium
Entire nerve trunk


Sixth degree (Mackinson) or mixed injuries occur in
which a nerve trunk is partially severed and
remaining part of trunk sustains 1st to 4thdegree
injury.
Mixed recovery pattern depending on degree of
injury to each portion of nerve.
Test for peripheral nerves of upper limb
• Radial nerve injury
– very high / high / low injury
– Wrist drop / finger drop / thumb drop
– Test for triceps/ /Brachioradialis/ wrist extensors /
extensor digitorum / EPL
• Median nerve
– High / low injury
– Test for FPL / FDS / FDP (lat. half) / FCR /Abd. Pollicis brevis
( pen test) / Oppenenspollicis
– See for pointing index / complete claw hand
• Ulnar nerve
– High / low palsy –ulnar paradox
– Test for FCU / Abd. digiti minimi / Interossei (dorsal - Egawa’s test ; palmar –
card test ) / lumbricals /Add. Pollicis (Froment’s sign / book test )
– Ulnar claw hand
Nerve injuries in the upper limb
Brachial plexus
Erbs – C 5 6 with or without c7 dysfunction
Extended elbow, adducted internally rotated
If serratus ant, levator scapulae, rombiods gone indicating lesion
medial to dorsal scapular and long thorasic
 Denervation potention in segmental paraspinous muscles inervated by
post rami.
Myelography- pseudo meningocele
Klumpke-C8 T1 with or without C 7 dysfunction
 Intrinsic of hand / flexors of wrist and finger
 Horner syndrome -ptosis /anhydrosis /miosis enopthalmos / loss of
cilio spinal reflex
Axillary nerve injury
• Sensory function:
sensation of an oval shaped
area over the lateral
shoulder “ sergeant's patch
“
• Motor function: it
innervates the deltoid
(shoulder abduction) and
teres minor (shoulder
external rotation) muscles.
• Common causes of injury:
Trauma, usually with
shoulder dislocation or
humeral fracture, iatrogenic
Axillary nerve injury manifestations
• Sensory loss: sharply-
defined region of sensory
loss over the lateral shoulder
“sergeant's patch “
• Motor loss: The patient
complains of shoulder
‘weakness’. Although
abduction can be initiated
(by supraspinatus), it cannot
be maintained.
• Deformity: wasting of the
deltoid
Radial nerve injury
• Sensory function: posterior
arm and forearm , lateral ⅔
of dorsum of hand and
proximal dorsal aspect of
lateral 3½ fingers
• Motor function: posterior
compartment of the arm and
forearm
• Common causes of injury:
fractures of proximal
humerus, shaft of humerus
or radius, stab wounds to
antecubital fossa, forearm or
wrist
Radial nerve injury manifestations
• Sensory loss: numbness of
skin over posterior
posterior forearm and
arm,
radial
distribution of dorsum of hand
• Motor loss: weak elbow ,
wrist , thump and MCPJ
extension, absent triceps
and supinator reflexes
• Deformity: “WRIST DROP”
deformity
Radial nerve
 In closed humeral fracture normal function may return
in 3-6 months
 In absence of nerve recovery and advancing tinel
exploration can be done after 3 months
 Tendon transfer can be done after 6 months
Median nerve injury
• Sensory function: Skin over
thenar eminence, lateral ⅔
palm of hand and palmar
aspect of lateral 3½ fingers
• Motor function: all muscles of
anterior compartment of
forearm except flexor carpi
ulnaris and the medial two
parts of flexor digitorum
profundus
• Common causes of injury:
supracondylar fractures of
humerus , compression by
carpal tunnel syndrome
Median nerve injury manifestations
• Sensory loss: numbness of
skin over thenar eminence
and median distribution of
hand
• Motor loss: weak forearm
pronation, wrist flexion
and abduction, and weak
finger flexion, weak pincer
grip
• Deformity: ape hand
deformity, wasting of thenar
m.
Median nerve
 Flexion of index and middle finger- side to side suture
with ulnar inervated fdp
 Fpl – brachioradilis / ECRL / ECU
 Thumb opposition- EIP
Ulnar nerve injury
• Sensory function: skin over
hypothenar eminence,
medial ⅓ palm of hand
,palmar aspect of lateral 1½
fingers
• Motor function: two
muscles of anterior
compartment of forearm ,
and most of the intrinsic
muscles of the hand
• Common causes of injury:
supracondylar fractures of
humerus , compression
cubital tunnel in the elbow.
Ulnar nerve injury manifestations
• Sensory loss: numbness of
skin over hypothenar
eminence and ulnar
distribution of hand
• Motor
flexion
loss: weak wrist
and adduction,
flexion of ring and little finger
DIPJs
HAND”• Deformity: “CLAW
deformity and wasting of
hypothenar m.
Ulnar nerve
restoration of intrinsic
If wrist extensors are strong to prevent flexion of wrist
and intrinsics are weak not paralyzed – bunnell transfer ( 4
fds, modified 1 ring finger fds split)
If wrist flexion is chronic habit- Riordan
Brand- ECRB/ 4 tailed free graft - volar to deep tansverse
metacarpal lig – lumbrical canal- radial side of extensor
apponeurosis except index finger difficult to re-educate
if wirst ext stronger than flex – brand – ECRL volarward 4
tail free graft
 If fds /wrist flex /ext not available- fowlers – EIP or
riordan modification of fowler- EIP + PL free plantaris
 If n0 muscle/ joint supple – zancolli capsulodeisis
 Bouvier test- if ext at ip present then static procedure
if ext not present dynamic procedure required
 Thumb adduction- omer- ring fds split brown- EIP in
palm near 3rd metacarpal
Nerve injuries in the
lower limb
Femoral nerve injury
• The femoral nerve may be injured by a gunshot
wound, hip or pelvic fractures, by pressure or
traction during an operation or by bleeding into the
thigh.
• Clinical manifestations: Quadriceps action is
lacking (week knee extension). There is
numbness of the anterior thigh and medial aspect
of the leg. The knee reflex is depressed. Severe
neurogenic pain is common
Sciatic nerve injury
• Division of the main sciatic nerve is rare except in
gunshot wounds. Traction lesions may occur with
traumatic hip dislocations and with pelvic
fractures.
• Clinical manifestations: In a complete lesion the
hamstrings and all muscles below the knee are
paralyzed; the ankle jerk is absent. Sensation is
lost below the knee, The patient walks with a drop
foot and a high-stepping gait to avoid dragging the
insensitive foot on the ground.
Common peroneal nerve injury
• The most frequent site of injury is just below the
knee as the nerve wraps around the lateral aspect
of the fibula, immediately before dividing into its
deep and superficial branches
• Common causes include: Trauma or injury to the
knee , Fracture of the fibula , Crossing the legs,
protracted squatting, and leg casts.
Common peroneal nerve injury
• Clinical manifestations:
• Drop foot deformity, the
patient can neither dorsiflex
nor evert the foot.
• He or she walks with a high-
stepping gait to avoid
catching the toes.
• Sensation is lost over the
front and outer half of the
leg and the dorsum of the
foot.
• Pain may be significant.
Time of Surgery
• Primary repair : First 24 hours
• Delayed primary repair : First 1 – 18 days
• Secondary repair : 18 days- 3months
Indications for surgery
1. When a sharp injury has obviously divided a nerve.
2. When abrading, avulsing or blast wounds have rendered
the condition of nerve unknown
3. When a nerve deficit follows a blunt or closed trauma & no
clinical or electrical evidence of regeneration has occurred
after an appropriate time
4. When a nerve deficit follows a penetrating wound as stab or
low velocity gunshot wound, part observed for evidence of
nerve regeneration for appropriate time.
Skeletal stability
Healthy tissue bed
Healthy nerve ends
No undue tension
Adequate soft tissue coverage
Types of Nerve Repair
1. Endoneurolysis
2. Partial Neurorrhaphy
3. Neurorrhaphy
1. Epineural
2. Epi-perineural
3. Perineural
4. Nerve grafting
Method of closing gap between nerve ends
1. Nerve grafting
2. Transposition
3. Bone resection
1. Mobilization ( critical nerve gap distance – value of
Grantham)
2. Positioning of extremity
–
–
Flex knee and elbow < 90°
Flex wrist < 40°
Motor
Proprioception
Touch
Temperature
Pain
Sympathetic
Recovery
Injury
Prognostic Factors of Outcomes
Patient
factor
•Age
• Level of injury (distal vs
proximal)
• Type of nerve (pure vs mixed
functions)
• Condition of nerve ends
Injury
factors
• Delay to repair
• Length of gap
Surgical
factors
History
• The diagnostic processbeginswith the physician obtaininga careful history.
• The family, social, and occupational histories are important for identifying familial occurrences
or toxicexposures.
Evaluation of patient with neuropathy
KeyQuestions:
•Isthe onsetsuddenorgradual?
• Isthe progressionrapidorslow?
• Isthe predominant manifestationsensory,motor,orboth?
•Isthe distribution focalor generalized,distalorproximal,
symmetric orasymmetric?
• Is there autonomicinvolvement?
• Doesthe patient haveanyassociateddiseases?
Relative predisposition to injury to peroneal
component than tibial
More superficial
Greater disability because of over stretched muscles
Poorer blood supply single funiculus with major nutrient
Artery exposed on surface
Large and tighty packed funiculi with less connective tissue
Oblique course ,fixed at sciatic notch and neck of fibula
 Can distinguish a recent from old injury in medico –
legal cases
 At initial post injury- normal or recruitment at this
point depends on injury pattern
 10 to 14 day- abnormal spontaneous rest potential ,
positive sharp waves in denervated myotome
 14 to 18 days- fibrillations appear
 3 months – polyphasic potentials / motor unit
potential increase progressively
EMG
Peripheral nerve injury by dr ashutosh

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Peripheral nerve injury by dr ashutosh

  • 1. Peripheral Nerve Injuries Dr.Ashutosh Kumar AP, Dept. of Orthopaedics RMCH, Bareilly
  • 2. Introduction • Peripheral nerve damage affecting the upper and lower extremities can vary widely in cause and extent. E.g. stretching, compression and transection. • Many disorders, ranging from mild carpal tunnel syndrome to severe brachial plexopathy, need to be considered in a patient presenting with pain, sensory loss, or weakness involving the shoulder, arm, or hand.
  • 3.
  • 4.
  • 5. Nerve injuries: Acute injury : Chronic injury Mechanism of injury: • Crush/compression • Strech/Traction • Laceration/Transection • Metabolic disturbances • Ischaemia • Radiation • Electrical injury • Thermal injury •
  • 9. Common nerve injuries Upper limb • Axillary nerve injury • Radial nerve injury • Median nerve injury • Ulnar nerve injury Lower limb • Femoral nerve injury • Sciatic nerve injury • Peroneal nerve injury
  • 10. Primary injury – Results from same trauma that injures a bone or joint – Radial nerve is the most commonly injured. Of humeral shaft fractures, 14 % is complicated by radial nerve injuries – Displaced osseous fragments – Stretching – Manipulation Secondary injury – Results from involvement of nerve by infection, scar, callous or vascular complications which may be hematoma, AVfistula, Ischemia or aneurysm
  • 11. Diagnosis of Peripheral nerve injuries • History – Which nerve ? – What level ? – What is the cause ? – What degree of injury ? – Old or fresh injury ?
  • 12. Diagnosis of Peripheral nerve inuries 1. Motor: – All muscles distal to the injury – paralyzed & atonic – – Atrophy : 50 -70 % in 1sttwomonths Striations & motor end plate configurations retained for 12 – 18 months (critical limit of delay)
  • 13. 2. Sensory : • Sensory loss usually follows a definite anatomical pattern, although factor of overlap from adjacent nerves may be present • Autonomous zone • Tinel’s sign
  • 14. (3) Reflex • Abolishes all reflexes transmitted by that nerve, either afferent or efferent arc. • Complete & incomplete lesion. So , not a reliable guide to injury severity. (4) Autonomic: • Loss of sweating • Loss of pilomotor response and • Vasomotor paralysis in autonomous zone
  • 15. (5) Others: • Trophic Changes • • Esp. hand and feet Skin – thin, glistening, breaks easily to form ulcers that heal slowly • Fingernails • Ridged, distorted and brittle • Osteoporosis (Reflex sympathetic dystrophy)
  • 16. Classification of nerve injuries Seddon Classification 1. Neuropraxia: 1. Minor contusion or compression with preservation of axis – cylinder of myelin sheath. 2. Impulse transmission physiologically interrupted. 3. Complete recovery in a few days toweeks
  • 17. 2. Axonotemesis : 1.More significant injury 2.Breakdown of axon and distal Wallerian degeneration butwith preservation of schwann cell & endoneurial tubes 3.Spontaneous regeneration with good functional recovery canbe expected
  • 18. 3.Neurotmesis 1.More severe injury 2.Complete anatomical severance, avulsion or crushing of nerve 3.Axon, Schwann cell & endoneurial tubes are completely disrupted 4.Spontaneous recovery cannot be expected unlessexplored
  • 19. Sunderland Classification   Each degree of injury suggesting a greater anatomical disruption with its correspondingly altered prognosis Anatomically various degrees (1st – 5th) representinjury to      Myelin Axon Endoneurial tube & it’scontent Perineurium Entire nerve trunk   Sixth degree (Mackinson) or mixed injuries occur in which a nerve trunk is partially severed and remaining part of trunk sustains 1st to 4thdegree injury. Mixed recovery pattern depending on degree of injury to each portion of nerve.
  • 20. Test for peripheral nerves of upper limb • Radial nerve injury – very high / high / low injury – Wrist drop / finger drop / thumb drop – Test for triceps/ /Brachioradialis/ wrist extensors / extensor digitorum / EPL • Median nerve – High / low injury – Test for FPL / FDS / FDP (lat. half) / FCR /Abd. Pollicis brevis ( pen test) / Oppenenspollicis – See for pointing index / complete claw hand • Ulnar nerve – High / low palsy –ulnar paradox – Test for FCU / Abd. digiti minimi / Interossei (dorsal - Egawa’s test ; palmar – card test ) / lumbricals /Add. Pollicis (Froment’s sign / book test ) – Ulnar claw hand
  • 21. Nerve injuries in the upper limb
  • 22. Brachial plexus Erbs – C 5 6 with or without c7 dysfunction Extended elbow, adducted internally rotated If serratus ant, levator scapulae, rombiods gone indicating lesion medial to dorsal scapular and long thorasic  Denervation potention in segmental paraspinous muscles inervated by post rami. Myelography- pseudo meningocele Klumpke-C8 T1 with or without C 7 dysfunction  Intrinsic of hand / flexors of wrist and finger  Horner syndrome -ptosis /anhydrosis /miosis enopthalmos / loss of cilio spinal reflex
  • 23. Axillary nerve injury • Sensory function: sensation of an oval shaped area over the lateral shoulder “ sergeant's patch “ • Motor function: it innervates the deltoid (shoulder abduction) and teres minor (shoulder external rotation) muscles. • Common causes of injury: Trauma, usually with shoulder dislocation or humeral fracture, iatrogenic
  • 24. Axillary nerve injury manifestations • Sensory loss: sharply- defined region of sensory loss over the lateral shoulder “sergeant's patch “ • Motor loss: The patient complains of shoulder ‘weakness’. Although abduction can be initiated (by supraspinatus), it cannot be maintained. • Deformity: wasting of the deltoid
  • 25. Radial nerve injury • Sensory function: posterior arm and forearm , lateral ⅔ of dorsum of hand and proximal dorsal aspect of lateral 3½ fingers • Motor function: posterior compartment of the arm and forearm • Common causes of injury: fractures of proximal humerus, shaft of humerus or radius, stab wounds to antecubital fossa, forearm or wrist
  • 26. Radial nerve injury manifestations • Sensory loss: numbness of skin over posterior posterior forearm and arm, radial distribution of dorsum of hand • Motor loss: weak elbow , wrist , thump and MCPJ extension, absent triceps and supinator reflexes • Deformity: “WRIST DROP” deformity
  • 27. Radial nerve  In closed humeral fracture normal function may return in 3-6 months  In absence of nerve recovery and advancing tinel exploration can be done after 3 months  Tendon transfer can be done after 6 months
  • 28. Median nerve injury • Sensory function: Skin over thenar eminence, lateral ⅔ palm of hand and palmar aspect of lateral 3½ fingers • Motor function: all muscles of anterior compartment of forearm except flexor carpi ulnaris and the medial two parts of flexor digitorum profundus • Common causes of injury: supracondylar fractures of humerus , compression by carpal tunnel syndrome
  • 29. Median nerve injury manifestations • Sensory loss: numbness of skin over thenar eminence and median distribution of hand • Motor loss: weak forearm pronation, wrist flexion and abduction, and weak finger flexion, weak pincer grip • Deformity: ape hand deformity, wasting of thenar m.
  • 30. Median nerve  Flexion of index and middle finger- side to side suture with ulnar inervated fdp  Fpl – brachioradilis / ECRL / ECU  Thumb opposition- EIP
  • 31. Ulnar nerve injury • Sensory function: skin over hypothenar eminence, medial ⅓ palm of hand ,palmar aspect of lateral 1½ fingers • Motor function: two muscles of anterior compartment of forearm , and most of the intrinsic muscles of the hand • Common causes of injury: supracondylar fractures of humerus , compression cubital tunnel in the elbow.
  • 32. Ulnar nerve injury manifestations • Sensory loss: numbness of skin over hypothenar eminence and ulnar distribution of hand • Motor flexion loss: weak wrist and adduction, flexion of ring and little finger DIPJs HAND”• Deformity: “CLAW deformity and wasting of hypothenar m.
  • 33. Ulnar nerve restoration of intrinsic If wrist extensors are strong to prevent flexion of wrist and intrinsics are weak not paralyzed – bunnell transfer ( 4 fds, modified 1 ring finger fds split) If wrist flexion is chronic habit- Riordan Brand- ECRB/ 4 tailed free graft - volar to deep tansverse metacarpal lig – lumbrical canal- radial side of extensor apponeurosis except index finger difficult to re-educate if wirst ext stronger than flex – brand – ECRL volarward 4 tail free graft
  • 34.
  • 35.  If fds /wrist flex /ext not available- fowlers – EIP or riordan modification of fowler- EIP + PL free plantaris  If n0 muscle/ joint supple – zancolli capsulodeisis  Bouvier test- if ext at ip present then static procedure if ext not present dynamic procedure required  Thumb adduction- omer- ring fds split brown- EIP in palm near 3rd metacarpal
  • 36. Nerve injuries in the lower limb
  • 37. Femoral nerve injury • The femoral nerve may be injured by a gunshot wound, hip or pelvic fractures, by pressure or traction during an operation or by bleeding into the thigh. • Clinical manifestations: Quadriceps action is lacking (week knee extension). There is numbness of the anterior thigh and medial aspect of the leg. The knee reflex is depressed. Severe neurogenic pain is common
  • 38. Sciatic nerve injury • Division of the main sciatic nerve is rare except in gunshot wounds. Traction lesions may occur with traumatic hip dislocations and with pelvic fractures. • Clinical manifestations: In a complete lesion the hamstrings and all muscles below the knee are paralyzed; the ankle jerk is absent. Sensation is lost below the knee, The patient walks with a drop foot and a high-stepping gait to avoid dragging the insensitive foot on the ground.
  • 39. Common peroneal nerve injury • The most frequent site of injury is just below the knee as the nerve wraps around the lateral aspect of the fibula, immediately before dividing into its deep and superficial branches • Common causes include: Trauma or injury to the knee , Fracture of the fibula , Crossing the legs, protracted squatting, and leg casts.
  • 40. Common peroneal nerve injury • Clinical manifestations: • Drop foot deformity, the patient can neither dorsiflex nor evert the foot. • He or she walks with a high- stepping gait to avoid catching the toes. • Sensation is lost over the front and outer half of the leg and the dorsum of the foot. • Pain may be significant.
  • 41. Time of Surgery • Primary repair : First 24 hours • Delayed primary repair : First 1 – 18 days • Secondary repair : 18 days- 3months
  • 42. Indications for surgery 1. When a sharp injury has obviously divided a nerve. 2. When abrading, avulsing or blast wounds have rendered the condition of nerve unknown 3. When a nerve deficit follows a blunt or closed trauma & no clinical or electrical evidence of regeneration has occurred after an appropriate time 4. When a nerve deficit follows a penetrating wound as stab or low velocity gunshot wound, part observed for evidence of nerve regeneration for appropriate time.
  • 43. Skeletal stability Healthy tissue bed Healthy nerve ends No undue tension Adequate soft tissue coverage
  • 44. Types of Nerve Repair 1. Endoneurolysis 2. Partial Neurorrhaphy 3. Neurorrhaphy 1. Epineural 2. Epi-perineural 3. Perineural 4. Nerve grafting
  • 45.
  • 46.
  • 47.
  • 48. Method of closing gap between nerve ends 1. Nerve grafting 2. Transposition 3. Bone resection 1. Mobilization ( critical nerve gap distance – value of Grantham) 2. Positioning of extremity – – Flex knee and elbow < 90° Flex wrist < 40°
  • 50. Prognostic Factors of Outcomes Patient factor •Age • Level of injury (distal vs proximal) • Type of nerve (pure vs mixed functions) • Condition of nerve ends Injury factors • Delay to repair • Length of gap Surgical factors
  • 51. History • The diagnostic processbeginswith the physician obtaininga careful history. • The family, social, and occupational histories are important for identifying familial occurrences or toxicexposures. Evaluation of patient with neuropathy KeyQuestions: •Isthe onsetsuddenorgradual? • Isthe progressionrapidorslow? • Isthe predominant manifestationsensory,motor,orboth? •Isthe distribution focalor generalized,distalorproximal, symmetric orasymmetric? • Is there autonomicinvolvement? • Doesthe patient haveanyassociateddiseases?
  • 52. Relative predisposition to injury to peroneal component than tibial More superficial Greater disability because of over stretched muscles Poorer blood supply single funiculus with major nutrient Artery exposed on surface Large and tighty packed funiculi with less connective tissue Oblique course ,fixed at sciatic notch and neck of fibula
  • 53.  Can distinguish a recent from old injury in medico – legal cases  At initial post injury- normal or recruitment at this point depends on injury pattern  10 to 14 day- abnormal spontaneous rest potential , positive sharp waves in denervated myotome  14 to 18 days- fibrillations appear  3 months – polyphasic potentials / motor unit potential increase progressively EMG