Infection and inflammation of heart includes endocarditis, myocarditis, peric...Mahesh Sivaji
Here we have seen about the infections and inflammatory diseases of the heart. It includes the endocarditis, Myocarditis, pericarditis, and the inflammation includes the rheumatic fever and heart diseases. Regarding the nursing care the betty neuman theory was applied for the better outcome in patient care. At last the journal references from the Indian medical council and the West Indian med from Jamaica they says that the Rheumatic fever (RF) and rheumatic heart disease (RHD) continue to be a major health hazard in most developing countries as well as sporadically in developed economies. They concluded that the infection and inflammatory disease of heart is completely preventable one. The study too says that it occurs mostly in the age group of 5-15 yr of children. Finally Rheumatic fever and rheumatic heart disease have relatively long and expensive hospital stays which are preventable by careful adherence to prevention programme. Thank you guys, i think this will useful for u to understand easily.
pericardial effusion, cardiac tamponade and myocardial rupturegufuabdikadir96
consists of P.E,cardiac tamponade and myocardial rupture and describes their definitions, pathophysiologies, clinical manifestations, dx, medical-surgical mgt and nursing mgt
for more inquiries/feedback; gufuabdikadir96@gmail.com
Infection and inflammation of heart includes endocarditis, myocarditis, peric...Mahesh Sivaji
Here we have seen about the infections and inflammatory diseases of the heart. It includes the endocarditis, Myocarditis, pericarditis, and the inflammation includes the rheumatic fever and heart diseases. Regarding the nursing care the betty neuman theory was applied for the better outcome in patient care. At last the journal references from the Indian medical council and the West Indian med from Jamaica they says that the Rheumatic fever (RF) and rheumatic heart disease (RHD) continue to be a major health hazard in most developing countries as well as sporadically in developed economies. They concluded that the infection and inflammatory disease of heart is completely preventable one. The study too says that it occurs mostly in the age group of 5-15 yr of children. Finally Rheumatic fever and rheumatic heart disease have relatively long and expensive hospital stays which are preventable by careful adherence to prevention programme. Thank you guys, i think this will useful for u to understand easily.
pericardial effusion, cardiac tamponade and myocardial rupturegufuabdikadir96
consists of P.E,cardiac tamponade and myocardial rupture and describes their definitions, pathophysiologies, clinical manifestations, dx, medical-surgical mgt and nursing mgt
for more inquiries/feedback; gufuabdikadir96@gmail.com
Acute Rheumatic Fever and Rheumatic Heart Disease, are two common conditions in children between 3-15 years of age following a Group B Streptococcal throat infection. We discuss these two conditions in the slides above, as well as their management.
This presentation is about pericarditis it's
pathophysiology Sign and symptoms classification types diagnostics treatment. This presentation also includes video demonstrations at the end
Pericarditis is an inflammation of the pericardium. causes of this RW infection like bacterial, viral, cancer, trauma, radiation theses are the causes of the pericardium. management of the antibiotic, pain killer, and cardiac steroid. and some surgical procedure is pericardial synthesis, heart transplantation
Acute Rheumatic Fever and Rheumatic Heart Disease, are two common conditions in children between 3-15 years of age following a Group B Streptococcal throat infection. We discuss these two conditions in the slides above, as well as their management.
This presentation is about pericarditis it's
pathophysiology Sign and symptoms classification types diagnostics treatment. This presentation also includes video demonstrations at the end
Pericarditis is an inflammation of the pericardium. causes of this RW infection like bacterial, viral, cancer, trauma, radiation theses are the causes of the pericardium. management of the antibiotic, pain killer, and cardiac steroid. and some surgical procedure is pericardial synthesis, heart transplantation
A complete presentation about all-aspects of the Alzheimer's disease, including Patho Physiology, Treatment, Nursing Management, Prevention, Disease Overview, Clinical Manifestation, etc.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
263778731218 Abortion Clinic /Pills In Harare ,ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group of receptionists, nurses, and physicians have worked together as a teamof receptionists, nurses, and physicians have worked together as a team wwww.lisywomensclinic.co.za/
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
2. Pericardium:
• Pericardium is the outer most
layer and is made up of two
fibrous serous sacs
Functions:
• Limits cardiac distention
• Restricts excessive movements
• Protect from injury
• Lubricate to prevent friction
• Hold the heart in place
3. Pericarditis
• Pericarditis is inflammation of the pericardium,
• Pericarditis is swelling and irritation of the thin, saclike tissue
surrounding the heart (pericardium).
• Pericarditis often causes sharp chest pain.
• The chest pain occurs when the irritated layers of the
pericardium rub against each other.
6. Symptoms
Chest pain, is the most common symptom,
• Characterized by Sharp or stabbing pain,
may dull, achy or pressure-like chest pain
• Locate behind the breastbone,
or on the left side of the chest.
• Radiate to the left shoulder and neck
• Get better when sitting up or leaning forward
• Referred to trapezius muscles (shoulder, upper back)
is only the distinction between pericardial pain and angina
7. Other signs and symptoms
• Fever
• Shortness of breath
• when lying down
• Pericardial friction rub,
• is a scratching, grating, and high-pitched sound one of the
hallmark finding in acute pericarditis
• Cough
• Fatigue
• Palpitation
• Pounding or racing heartbeat)
8. Types
• Acute pericarditis:
• Begins suddenly but doesn't last longer than three weeks
• Difficult to differentiate between acute pericarditis and MI pain
• Recurrent pericarditis:
• Occurs about four to six weeks after an episode of acute pericarditis
with no symptoms in between.
• Incessant pericarditis:
• Lasts about four to six weeks but less than three months.
• The symptoms are continuous.
• Chronic constrictive pericarditis;
• usually develops slowly and lasts longer than three months.
9. Complications
• Pericardial effusion
• The fluid buildup can lead to further heart complications.
• Constrictive pericarditis).
• long-term pericarditis develop permanent thickening and scarring of the
heart lining
• The changes prevent the heart from filling and emptying properly.
• Cardiac tamponade)
• Pressure on the heart due to fluid buildup
• Prevents the heart from filling properly.
• Causing a dramatic drop in blood pressure.
• A life-threatening condition requires emergency treatment
10. Diagnosis
• History and Physical Examination
• Sharp chest pain and shortness of breathing are 2 major clues
• Heart Auscultation:
• Rubbing or creaking sound, called “pericardial rub” is the best
heard when the pt lean forward, hold breath and breathe out.
• Crackles in the lungs, which are signs of pleurisy or pericardial
effusion
• ECG: Normal/specific defused changes over aperid of hours to
days/wks. we
• PR segment depression,
• ST segment elevation and
• T wave flattening
12. • Chest X-ray
• to see the size of the heart and any fluid in lungs.
• Echocardiogram (echo) ;
• To find fluid or pericardial effusion around the heart
• Cardiac MRI;
• CT scan;
• to look for calcium in the pericardium, fluid, inflammation, tumors
around the heart
• Cardiac catheterization:
• to confirm a diagnosis of constrictive pericarditis.
• Blood tests
• ESR, CRP,
• To confirm heart attack
• To find the cause of pericarditis.
•
13. Collaborative Care
Medical treatment:
• Pain Relievers:
• Nonsteroidal anti-inflammatory (NSAIDs) use to treat pain and inflammation
such as aspirin or Ibuprofen
• Antibiotics :
• to reduce inflammation and pain
• Steroids:
• strong anti-inflammatory drug, may used in pericarditis secondary to
autoimmune conditions
• Pericardiocentesis:
• is usually performed for pericardial effusion with cardiac tamponade,
purulent pericarditis and a high suspicious of neoplasm
14. Nursing management:
• Strict bed rest
• Keep in prop-upped position
• Elevate the bed at 45 degree
• Provide an overbed table for support
• Observe for post anti-inflammatory drugs complications such as upper GI
bleed, gastric upset etc
• Advise to take these drugs with food and milk
• Instruct avoid alcohol beverages
• Take anxiety-reduce measures by explaining performed procedures and
possible cause of pain , treatment and prognosis
• Reassure the client