Pericarditis is an inflammation of the pericardium that can be caused by infection, connective tissue disorders, medications, or other cardiac issues. It leads to chest pain and may accumulate fluid in the pericardial sac, causing cardiac tamponade. Diagnosis involves echocardiogram, CT scan, or MRI. Treatment focuses on determining the cause, relieving symptoms like pain with NSAIDs or corticosteroids, and detecting signs of tamponade. Nursing care manages pain and encourages activity as the condition improves.