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PRESENTED BY: DR.SHILPA PRAJAPATI (1st YEAR MPT)
   An unpleasant sensory and
    emotional experience associated
    with actual or potential tissue
    damage, or described in term of
    such damage.



          -International Association For the Study of pain
NOCICEPTIVE                NEUROPATHIC



Somatic                Visceral
• bones, joints        • Organs –
• connective tissues     heart, liver,
• muscles                pancreas, gut,
                         etc.



            Deafferentation       Sympathetic   Peripheral
                                   Maintained
•   Aching, often constant
•   May be dull or sharp
•   Often worse with movement
•   Well localized

Eg
– Bone & soft tissue
– chest wall
   Somatic pain and visceral pain are actually two
    very different types of pain. Somatic pain comes
    from the skin and deep tissues, while visceral pain
    comes from the internal organs. Both somatic pain
    and visceral pain are detected the same way:
    Nociceptors, or pain-detecting nerves, send an
    impulse from the painful site up through the spinal
    cord and to the brain for interpretation and
    reaction. This is called nociceptive pain, and
    differs from neuropathic pain, which is caused by
    nerve damage. Though they are detected in similar
    ways, somatic pain and visceral pain do not feel
    the same
   How Somatic Pain Feels
   Somatic pain is generally described as
    musculoskeletal pain. Because many nerves
    supply the muscles, bones and other soft
    tissues, somatic pain is usually easier to
    locate than visceral pain. It also tends to be
    more intense. Some chronic pain conditions
    caused by somatic pain include:
•   Constant or crampy
•   Aching
•   Poorly localized
•   Referred

Eg
– CA pancreas
– Liver capsule distension
– Bowel obstruction
   How Visceral Pain Feels
   Visceral pain is internal pain. It comes from
    the organs or the blood vessels, which are
    not as extensively innervated, or supplied
    by, sensory nerves. Unlike somatic pain,
    visceral pain may feel dull and vague, and
    may be harder to pinpoint. Some common
    types of visceral pain include:
COMPONENT          DESCRIPTORS              EXAMPLES
   Steady,     •   Burning, Tingling    • Diabetic neuropathy
 Dysesthetic   •   Constant, Aching
                                        • Post-herpetic
               •   Squeezing, Itching     neuropathy
               •   Allodynia
               •   Hypersthesia

 Paroxysmal,   • Stabbing               • trigeminal neuralgia
  Neuralgic
               • Shock-like, electric   • may be a component
               • Shooting                 of any neuropathic
                                          pain
               • Lancinating
   MECHANORECEPTORS
    -Meissner’s Corpuscles (light touch)
    - Pacinian corpuscles (deep pressure)
    - merkel's corpuscles (deep pressure)

   THERMORECEPTOR
     -krause's end bulbs (decrease temperature,
    touch )
     -ruffini corpuscles( in the skin)

   PROPRIOCEPTOR
     -muscle spindle , golgi tendon
   NOCICEPTOR
   ACUTE:
     onset is well defined,

     response to tissue injury,
     responds to pain treatment,
     associated with anxiety,
     affects the individual

   CHRONIC PAIN:
     Onset is ill defined,
     response to change in nervous system,
     less response to medication,
     associated with depression,
     involves social network
   MELZACK & WALL,1965- Substentia
    Gelatinosa(SG) in dorsal horn of spinal cord acts
    as a "gate"- only allows one type of impulses to
    connect with the SON

   Transmission Cell(T-cell)- distal end of the SON

   If A-beta neurons are stimulated- SG is activated
    which closes the gate to A-delta & c neurons

    If B-delta and C neurons are stimulated- SG is
    blocked which closes the gate to A-beta neurons
   Gate - located in the dorsal horn of the spinal cord

   Smaller, slower nerve carry pain impulses
   Larger, faster nerve fibers carry other sensations

   Impulses from faster fibers arriving at gate 1st inhibit
    pain impulses (acupuncture/pressure, cold, heat, chem. skin
    irritation).
                   Brain



                                                     Pain
                               Gate (T
                               cells/ SG)            Heat, Cold,
                                                     Mechanical
   Descending neurons are activated by:
    stimulation of A-delta & C neurons, cognitive
    processes, anxiety, depression, previous
    experiences, expectations which Cause
    release of enkephalins (PAG).

   Enkephalin interneuron in area of the SG
    blocks A-delta & C neurons
   Least understood of all the theories

   Stimulation of A-delta & C fibers causes release of B-
    endorphins from the PAG

   Mechanism of action – similar to enkephalins to block
    ascending nerve impulses

   Examples: TENS (low freq. & long pulse duration)
    Unlike specificity theory, pattern theory
    suggests that there are no separate systems for
    receiving pain, but instead the nerves are shared
    with other senses like touch.

    The most important feature of pain is the
    pattern of activity in the nervous system. So, too
    much stimulation (eg too much touch) will cause
    pain.
   Reduce pain!

   Control acute pain!

   Improve healing process

   Reduce inflammation and edema

   Decrease spasm and improve muscle
    contraction
   Use to control pain

   Muscle spasm decrease as result of
      decrease activity in gamma motor efferent,
     decrease excitability of muscle spindle and
     increase activity of Golgi tendon organs
   Moist heat packs and paraffin are examples
    of therapeutic conductive heating

   Therapeutic convective heating take place
    during hydrotherapy

   Therapeutic radiant is supplied infrared
   Cold therapy is the best modality for acute
    inflammatory reactions like:
       Acute inflammation of the bursa (bursitis)
       Epicondylitis (tennis elbow, golfer’s elbow)
       Acute trauma

   Cold therapy reduce:
     Muscle  spasm secondary to:
     Underlying joint and skeletal pathology
     Nerve root irritation
     Edema, hyperemia (excess blood in tissue) and pain
     Due to its vasoconstrictive (constriction of blood
      vessels) effect
   A local decrease in tissue temperature
   Reduction in metabolism
   Vasoconstriction (initially)
   Reduce blood flow (initially),
   Reduce muscle excitability, muscle spindle
    activity
   Reduce nerve conduction velocity
   Reduction in lymphatic and venous drainage
   Reduce Decrease formation and accumulation of
    edema
   Anesthesia
   After some minutes the vasoconstriction may
    give way to a marked vasodilatation which it self
    may last some 15minute before being replaced
    by another episode of vasoconstriction

   This alteration is called the “Lewis hunting
    reaction” (Lewis, 1930), in the sense that the
    vessels hunts about its mean position
   Electromagnetic waves that produce heat

   Frequency of 27.12 MHz and wavelength > 11 m.

   Use in
     muscle spasm- pain relief,


       Delayed healing

     Chronic   inflammation- increase blood circulation

     Fibrosis-   increases extensibility of fibrous tissue
   Principle effect is production of heat in the tissues
                    ↓
   rise temperature of that part
                    ↓
   Relaxation of muscle and increase the efficiency
    of their action
                    ↓
   Increase blood supply ensuring the optimum
    condition for the muscle contraction.
parameters   Chronic condition    Acute condition




Intensity    comfortable warmth   Below sensation of
                                  warmth



Duration     20 minutes           10 minutes


Frequency    Daily                Twice a day
   Electromagnetic radiation

   Frequency 2450 MHz and wavelength 12.245 cm

   Relief pain- in traumatic
    and rheumatic condition

   Muscle spasm
   Inflammation- increase blood supply and resorption
     of edema
   Delayed healing- promote healing
   Principle effect is production of heat in the tissues
                    ↓
   rise temperature of that part
                    ↓
   Relaxation of muscle and increase the efficiency of
    their action
                    ↓
   Increase blood supply ensuring the optimum
     condition for the muscle contraction.
   To produce deep tissue heat by molecular friction

   It helps to:
       Decrease the joint pain

       Prepare the joint for mobilization/manipulation

       It can break adhesions and calcification
        (e.g. calcific bursitis)

        Combined with deep tissue massage (trigger point
        therapy) it is effective for treatment of myofascitis
   It is impossible to treat C or A fiber
    selectively, ultrasound provides both pain
    relief and relief from muscle spasm

   Sounding of C fibers produce pain relief
    whereas sounding of large diameter fibers
    bring relief of spasm by changing gamma
    fiber activity, making muscle fiber less
    sensitive to stretch.
   Transcutaneous Electrical Nerve stimulation
   TYPES
     High tens or conventional tens
    (high freq:100-150Hz, law intensity:12-30mamp)

     Low tens or acupuncture tens
     (high intensity:300mamp, law freq:1-5Hz)

     Burst   tens(50-150Hz)

     Brieftens
     (high freq:100Hz, law intensity:20-50mamp)
     Modulated tens
   Tens selectively stimulates the low-
    threshold, large-diameter A-beta fibers

   It resulting in presynaptic inhibition within
    the dorsal horns

   Tens delivered at low rate is thought to
    facilitate elevation of the level of
    endogenous opiates in the CNS
Pulse shape               Rectangular type impulses

 Pulse width               100 microsecond, generally 50
                           microsec- 300 microsec
 Inensity                  0 – 60 milliamp, satisfactory
                           intensity till tingling sensation


Frequency range            effect

1 – 250 pulse per second   decrease pain

50 – 100 pps               sensory level (high level)

2 – 3 pps                  Motor level (low level)


2 pps                      Increase in the pain threshold
   short frequency therapeutic current

   Types
     Plain
     Surged   faradic

   Its use
     Muscle contraction that is inhibited by pain
     Pumping action which result in increase venous
      and lymphatic returns
   Chemical ions are driven through the skin by small
    electrical current

   Ionizable compounds are placed on the skin under the
    electrode, which when polarized by direct(galvanic)
    current, repels the ion of like charge into the tissue

   Ions are known to be effective analgesics:
     Xylocain
     Hydrocortisone
     Manesium
     Iodine
     salicylate
   Light amplification by stimulated emission of
    radiation

   A low intensity laser therapy is used

   It resolve inflammation and infection
   Reduce pain
   Increase speed, quality and strength of tissue repair

   TYPES:
     Rubby laser,
     Helium-neon laser,
     Diod laser
Laser―photons
                       ↓
  Visible red light absorbed in the mitochondria,
   infrared light absorbed at the cell membrane
                       ↓
Single oxygen production
                       ↓
Formation of proton gradients across cell membrane and
 across membrane of mitochondria
                       ↓
Physiological changes
Change in cell membrane permeability
Increase ATP levels-DNA production
Influences cell metabolism
                       ↓
Activation of regulatory process
1)    Power Density (W/cm2) =
     Laser Output Power (W)/Beam   area (cm2)

2) Beam Area (cm2) = Diameter(cm)2 x 0.7854

3) Energy (Joules)=Laser Output Power (Watts) x Time(Sec)

4) Energy Density (Joule/cm2)=Laser Output Power (Watts) x
   Time(Sec)/Beam Area (cm2)

5) Treatment Time (Seconds)=Energy Density
   (Joules/cm2)/Output Power Density (W/cm2)
THANK
 YOU!

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Pain managment with modalities 1

  • 1. PRESENTED BY: DR.SHILPA PRAJAPATI (1st YEAR MPT)
  • 2. An unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in term of such damage. -International Association For the Study of pain
  • 3. NOCICEPTIVE NEUROPATHIC Somatic Visceral • bones, joints • Organs – • connective tissues heart, liver, • muscles pancreas, gut, etc. Deafferentation Sympathetic Peripheral Maintained
  • 4. Aching, often constant • May be dull or sharp • Often worse with movement • Well localized Eg – Bone & soft tissue – chest wall
  • 5. Somatic pain and visceral pain are actually two very different types of pain. Somatic pain comes from the skin and deep tissues, while visceral pain comes from the internal organs. Both somatic pain and visceral pain are detected the same way: Nociceptors, or pain-detecting nerves, send an impulse from the painful site up through the spinal cord and to the brain for interpretation and reaction. This is called nociceptive pain, and differs from neuropathic pain, which is caused by nerve damage. Though they are detected in similar ways, somatic pain and visceral pain do not feel the same
  • 6. How Somatic Pain Feels  Somatic pain is generally described as musculoskeletal pain. Because many nerves supply the muscles, bones and other soft tissues, somatic pain is usually easier to locate than visceral pain. It also tends to be more intense. Some chronic pain conditions caused by somatic pain include:
  • 7. Constant or crampy • Aching • Poorly localized • Referred Eg – CA pancreas – Liver capsule distension – Bowel obstruction
  • 8. How Visceral Pain Feels  Visceral pain is internal pain. It comes from the organs or the blood vessels, which are not as extensively innervated, or supplied by, sensory nerves. Unlike somatic pain, visceral pain may feel dull and vague, and may be harder to pinpoint. Some common types of visceral pain include:
  • 9. COMPONENT DESCRIPTORS EXAMPLES Steady, • Burning, Tingling • Diabetic neuropathy Dysesthetic • Constant, Aching • Post-herpetic • Squeezing, Itching neuropathy • Allodynia • Hypersthesia Paroxysmal, • Stabbing • trigeminal neuralgia Neuralgic • Shock-like, electric • may be a component • Shooting of any neuropathic pain • Lancinating
  • 10. MECHANORECEPTORS -Meissner’s Corpuscles (light touch) - Pacinian corpuscles (deep pressure) - merkel's corpuscles (deep pressure)  THERMORECEPTOR -krause's end bulbs (decrease temperature, touch ) -ruffini corpuscles( in the skin)  PROPRIOCEPTOR -muscle spindle , golgi tendon  NOCICEPTOR
  • 11. ACUTE:  onset is well defined,  response to tissue injury,  responds to pain treatment,  associated with anxiety,  affects the individual  CHRONIC PAIN:  Onset is ill defined,  response to change in nervous system,  less response to medication,  associated with depression,  involves social network
  • 12. MELZACK & WALL,1965- Substentia Gelatinosa(SG) in dorsal horn of spinal cord acts as a "gate"- only allows one type of impulses to connect with the SON  Transmission Cell(T-cell)- distal end of the SON  If A-beta neurons are stimulated- SG is activated which closes the gate to A-delta & c neurons  If B-delta and C neurons are stimulated- SG is blocked which closes the gate to A-beta neurons
  • 13. Gate - located in the dorsal horn of the spinal cord  Smaller, slower nerve carry pain impulses  Larger, faster nerve fibers carry other sensations  Impulses from faster fibers arriving at gate 1st inhibit pain impulses (acupuncture/pressure, cold, heat, chem. skin irritation). Brain Pain Gate (T cells/ SG) Heat, Cold, Mechanical
  • 14. Descending neurons are activated by: stimulation of A-delta & C neurons, cognitive processes, anxiety, depression, previous experiences, expectations which Cause release of enkephalins (PAG).  Enkephalin interneuron in area of the SG blocks A-delta & C neurons
  • 15. Least understood of all the theories  Stimulation of A-delta & C fibers causes release of B- endorphins from the PAG  Mechanism of action – similar to enkephalins to block ascending nerve impulses  Examples: TENS (low freq. & long pulse duration)
  • 16. Unlike specificity theory, pattern theory suggests that there are no separate systems for receiving pain, but instead the nerves are shared with other senses like touch.  The most important feature of pain is the pattern of activity in the nervous system. So, too much stimulation (eg too much touch) will cause pain.
  • 17. Reduce pain!  Control acute pain!  Improve healing process  Reduce inflammation and edema  Decrease spasm and improve muscle contraction
  • 18. Use to control pain  Muscle spasm decrease as result of  decrease activity in gamma motor efferent,  decrease excitability of muscle spindle and  increase activity of Golgi tendon organs
  • 19. Moist heat packs and paraffin are examples of therapeutic conductive heating  Therapeutic convective heating take place during hydrotherapy  Therapeutic radiant is supplied infrared
  • 20. Cold therapy is the best modality for acute inflammatory reactions like:  Acute inflammation of the bursa (bursitis)  Epicondylitis (tennis elbow, golfer’s elbow)  Acute trauma  Cold therapy reduce:  Muscle spasm secondary to:  Underlying joint and skeletal pathology  Nerve root irritation  Edema, hyperemia (excess blood in tissue) and pain  Due to its vasoconstrictive (constriction of blood vessels) effect
  • 21. A local decrease in tissue temperature  Reduction in metabolism  Vasoconstriction (initially)  Reduce blood flow (initially),  Reduce muscle excitability, muscle spindle activity  Reduce nerve conduction velocity  Reduction in lymphatic and venous drainage  Reduce Decrease formation and accumulation of edema  Anesthesia
  • 22. After some minutes the vasoconstriction may give way to a marked vasodilatation which it self may last some 15minute before being replaced by another episode of vasoconstriction  This alteration is called the “Lewis hunting reaction” (Lewis, 1930), in the sense that the vessels hunts about its mean position
  • 23. Electromagnetic waves that produce heat  Frequency of 27.12 MHz and wavelength > 11 m.  Use in  muscle spasm- pain relief,  Delayed healing  Chronic inflammation- increase blood circulation  Fibrosis- increases extensibility of fibrous tissue
  • 24. Principle effect is production of heat in the tissues ↓  rise temperature of that part ↓  Relaxation of muscle and increase the efficiency of their action ↓  Increase blood supply ensuring the optimum condition for the muscle contraction.
  • 25. parameters Chronic condition Acute condition Intensity comfortable warmth Below sensation of warmth Duration 20 minutes 10 minutes Frequency Daily Twice a day
  • 26. Electromagnetic radiation  Frequency 2450 MHz and wavelength 12.245 cm  Relief pain- in traumatic and rheumatic condition  Muscle spasm  Inflammation- increase blood supply and resorption of edema  Delayed healing- promote healing
  • 27. Principle effect is production of heat in the tissues ↓  rise temperature of that part ↓  Relaxation of muscle and increase the efficiency of their action ↓  Increase blood supply ensuring the optimum condition for the muscle contraction.
  • 28. To produce deep tissue heat by molecular friction  It helps to:  Decrease the joint pain  Prepare the joint for mobilization/manipulation  It can break adhesions and calcification (e.g. calcific bursitis)  Combined with deep tissue massage (trigger point therapy) it is effective for treatment of myofascitis
  • 29. It is impossible to treat C or A fiber selectively, ultrasound provides both pain relief and relief from muscle spasm  Sounding of C fibers produce pain relief whereas sounding of large diameter fibers bring relief of spasm by changing gamma fiber activity, making muscle fiber less sensitive to stretch.
  • 30.
  • 31.
  • 32. Transcutaneous Electrical Nerve stimulation  TYPES  High tens or conventional tens (high freq:100-150Hz, law intensity:12-30mamp)  Low tens or acupuncture tens (high intensity:300mamp, law freq:1-5Hz)  Burst tens(50-150Hz)  Brieftens (high freq:100Hz, law intensity:20-50mamp)  Modulated tens
  • 33.
  • 34. Tens selectively stimulates the low- threshold, large-diameter A-beta fibers  It resulting in presynaptic inhibition within the dorsal horns  Tens delivered at low rate is thought to facilitate elevation of the level of endogenous opiates in the CNS
  • 35. Pulse shape Rectangular type impulses Pulse width 100 microsecond, generally 50 microsec- 300 microsec Inensity 0 – 60 milliamp, satisfactory intensity till tingling sensation Frequency range effect 1 – 250 pulse per second decrease pain 50 – 100 pps sensory level (high level) 2 – 3 pps Motor level (low level) 2 pps Increase in the pain threshold
  • 36. short frequency therapeutic current  Types  Plain  Surged faradic  Its use  Muscle contraction that is inhibited by pain  Pumping action which result in increase venous and lymphatic returns
  • 37. Chemical ions are driven through the skin by small electrical current  Ionizable compounds are placed on the skin under the electrode, which when polarized by direct(galvanic) current, repels the ion of like charge into the tissue  Ions are known to be effective analgesics:  Xylocain  Hydrocortisone  Manesium  Iodine  salicylate
  • 38. Light amplification by stimulated emission of radiation  A low intensity laser therapy is used  It resolve inflammation and infection  Reduce pain  Increase speed, quality and strength of tissue repair  TYPES:  Rubby laser,  Helium-neon laser,  Diod laser
  • 39. Laser―photons ↓ Visible red light absorbed in the mitochondria, infrared light absorbed at the cell membrane ↓ Single oxygen production ↓ Formation of proton gradients across cell membrane and across membrane of mitochondria ↓ Physiological changes Change in cell membrane permeability Increase ATP levels-DNA production Influences cell metabolism ↓ Activation of regulatory process
  • 40. 1) Power Density (W/cm2) = Laser Output Power (W)/Beam area (cm2) 2) Beam Area (cm2) = Diameter(cm)2 x 0.7854 3) Energy (Joules)=Laser Output Power (Watts) x Time(Sec) 4) Energy Density (Joule/cm2)=Laser Output Power (Watts) x Time(Sec)/Beam Area (cm2) 5) Treatment Time (Seconds)=Energy Density (Joules/cm2)/Output Power Density (W/cm2)