Piriformis syndrome is a condition where sciatica symptoms occur due to involvement of the piriformis muscle, often caused by muscle tightness or trauma. It results in entrapment of the sciatic or pudendal nerves, leading to pain, tingling, and numbness in the buttocks, thigh, and leg. Diagnosis involves physical tests like the Freiberg test and treatment focuses on stretching, strengthening, and modalities like massage to relieve tightness while surgery is rarely needed.