This document provides guidance on pre-anaesthetic evaluation for paediatric patients. It discusses the importance of a thorough history, physical exam, and assessment to plan safe anaesthesia and post-operative care. The key components of evaluation are outlined, including assessing medical history, performing a physical exam, reviewing investigations, determining ASA classification, obtaining consent, and preparing the patient. Factors like temperature control, fluid management, and psychological preparation are also addressed to optimize patient safety and outcomes.
Evolution of Boyle's Anaesthesia apparatusSelva Kumar
The machine which is used to give general anaesthesia is generally called as Boyle's machine even though there are many other names for that machine.This presentation tries to trace the development of the Boyles machine from 1846.
Brief discussion on ultrasonography of the chest: Benefits, Techniques and Instrumentation, Normal Anatomy, Diagnostic US of the chest, Limitations of Thoracic US, US based differential diagnosis, Take home points.
Evolution of Boyle's Anaesthesia apparatusSelva Kumar
The machine which is used to give general anaesthesia is generally called as Boyle's machine even though there are many other names for that machine.This presentation tries to trace the development of the Boyles machine from 1846.
Brief discussion on ultrasonography of the chest: Benefits, Techniques and Instrumentation, Normal Anatomy, Diagnostic US of the chest, Limitations of Thoracic US, US based differential diagnosis, Take home points.
Slideshow is from the University of Michigan Medical School's M1 Cardiovascular / Respiratory sequence
View additional course materials on Open.Michigan:
openmi.ch/med-M1Cardio
Slideshow is from the University of Michigan Medical School's M1 Cardiovascular / Respiratory sequence
View additional course materials on Open.Michigan:
openmi.ch/med-M1Cardio
Hospital Dental Services for Children and the Use of General AnesthesiaAl-lehyani
“a drug-induced loss of consciousness
during which patients are not arousable, even by painful
stimulation. The ability to independently maintain ventilatory
function is often impaired. Patients often require assistance
in maintaining a patent airway, and positive-pressure
ventilation may be required because of depressed spontaneous
ventilation or drug-induced depression of neuromuscular
function. Cardiovascular function may be impaired.
Cardiac catheterization (kath-uh-tur-ih-ZAY-shun) is a procedure used to diagnose and treat cardiovascular conditions. During cardiac catheterization, a long thin tube called a catheter is inserted in an artery or vein in your groin, neck or arm and threaded through your blood vessels to your heart.
Using this catheter, doctors can then do diagnostic tests as part of a cardiac catheterization. Some heart disease treatments, such as coronary angioplasty, also are done using cardiac catheterization.
Usually, you'll be awake during cardiac catheterization, but given medications to help you relax. Recovery time for a cardiac catheterization is quick, and there's a low risk of complications.
Neonatal and Pediatric Critical Care - Mostafa QalavandWang Lang
Neonatal and pediatric critical care is markedly different from adult critical care because of the physiologic and hemodynamic dissimilarities between immature and adult animals. Clinicians are often wary of treating these patients because of their small size and the presumptive limitations in diagnostic and therapeutic interventions. Nevertheless, we have the ability to treat these young animals aggressively. In doing so, however, we must be cognizant of the unique distinctions among pediatric patients with regard to normal physiologic variables that affect physical examination findings and diagnostic test results.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
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Paediatric Pre-Anaesthetic Evaluation.pptx
1. D R . S H R I N I V A S K U L K A R N I
P R O F E S S O R & H O D
D E P T O F E M E R G E N C Y M E D I C I N E
A V M V & H P O N D I C H E R R Y
Paediatric Pre-Anaesthetic
Evaluation
2. INTRODUCTION
Careful preoperative assessment is the cornerstone
of safe anaesthetic practice.
Allows for careful planning of the child’s surgical and
post-anaesthetic care.
Evaluation of the child’s present health, past medical
and anaesthetic history, and review of relevant
investigations.
These factors then integrated with the anticipated
effects of surgery to allow planning of appropriate
anesthetic goals.
3. OBJECTIVES OF PAE
Evaluate the patient’s medical condition to ensure that it
has been optimised
Plan anaesthetic technique and peri-operative care.
Develop a rapport with the patient to allay anxiety and
facilitate conduct of anaesthesia
Allow appropriate discussion with the patient and/or
guardian regarding anaesthesia, peri-operative care and
pain management
Obtain informed consent for anaesthesia and related
procedures.
5. HISTORY
Social and Demographic Details: Name, Age, Sex,
Guardian/Informant’s name, Educational Status of
both child and Parents, the family’s SocioEconomic
Status, Contact details.
Chief Complaint
History of Presenting Illness : elaboration of the
presenting complaint
History of any co-morbid conditions, congenital
abnormalities
6. Respiratory System :
-Recent history of URTI/LRTI
-history suggestive of airway compromise
- OSA
- History of bronchial asthma
8. Child with URTI
Peri-operative problems include laryngospasm,
bronchospasm, airway obstruction by secretion,
intraoperative atelectasis and hypoxemia, post-extubation
stridor.
Incidence greater in infants <1 year old.
Recommendations for anaesthesia in a child with RTI
depends on its severity and the nature of the surgery (elective,
emergency, minor or major)
The child with mild RTI (no fever, clear nasal discharge, mild
cough, child active, feeding well) can be anaesthetized for
minor surgical procedure without tracheal intubation.
Surgery for the child with active RTI (fever, recent onset of
purulent nasal discharge, cough) should be postponed for at
least 2 weeks, and ideally 4-6 weeks; LMA to be used if
possible, to avoid airway manipulation.
9. Cardiovascular System :
- Congenital or Rheumatic Heart Disease
- History of cyanotic or breath holding spells
- Consider possibility of cardiac lesion if child has any
associated congenital conditions : tracheoesophageal
fistula, esophageal atresia, Down Syndrome,
VACTERL anomalies
- History of Failure to thrive
- Medication history for CVS disease : Beta blockers,
anticoagulants, antihypertensives, digoxin,
antiplatelet drugs
10. CNS :
- Seizure history, including h/o anticonvulsants
- raised ICP features
- Progressive neurodevelopmental impairment
- Behavioural abnormalities
Hepatic and Renal System History:
- Kernicterus, Jaundice
- Nephrotic or Nephritic symptoms
- Obstructive uropathy symptoms
13. Antenatal History:
- booked/not booked case
- intake of Iron and Folic Acid tablets
- any other drug intake
- any infections/ febrile illness
- GDM, PIH, other maternal comorbid conditions
14. Birth History:
-gestational age at birth
-mode of delivery
-birth weight
-order of birth (whether firstborn)
-baby cried immediately after birth
- any NICU admission
- when breastfeeding was started
- h/o apnoeic spells- more likely to develop apnoea
following anaesthesia and should not be accepted for
day care procedures until they are atleast 50 wks
gestation.
15. Developmental History:
- Gross Motor, Fine Motor, Social, Language
Immunization History:
- Appropriate to age as per IAP schedule.
- Children may have received vaccines. Surgery should
be planned in accordance with the vaccination
programme.
16. Family History:
- Consanguinous or Non-consanguinous marriage
- Pedigree chart
- h/o sudden intraoperative death, or hyperthermia after
surgery : indicates risk of malignant hyperthermia
Past History:
- Any previous surgeries requiring anaesthesia, blood
transfusions
- History of mechanical ventilation
- Drug History
Personal History:
- Appetite, Sleep, Bowel and Bladder habits
- Passive smoking
- Medical allergies
17. GENERAL PHYSICAL EXAMINATION
Anthropometry : General nutritional state, weight,
height, mid arm circumference, head circumference
Skin and mucosal colour : pallor, icterus, cyanosis
Clubbing, Koilonychia
Heart Rate, Blood Pressure, Capillary Filling Time,
Oxygen Saturation.
Respiratory Rate, Character of respiration
Spine : spina bifida; whether hiatus well felt
Potential sites for venepuncture – mark out for EMLA
(Eutectic Mixture of Local Anaesthetic) application
Presence or absence of nasal discharge
18. AIRWAY ASSESSMENT
Inter Incisor Gap
Dentition
Modified Mallampatti Classification
Upper Lip Bite Test
Neck Circumference
Thyromental Distance
Sternomental Distance
19. Class I = visualize the soft palate, fauces, uvula, anterior
and posterior pillars.
Class II = visualize the soft palate, fauces and uvula.
Class III = visualize the soft palate and the base
of the uvula.
Class IV = soft palate is not visible at all.
Modified Mallampati Classification
20. Equipment Category Recommended Equipment
Airways
Oral and nasopharyngeal (trumpet) airways in all
sizes for preterm infants to adults
Endotracheal tubes
Cuffed and uncuffed endotracheal tubes of
various size (uncuffed down to size 2.0 mm ID)
Stylets Stylets in several sizes
Laryngoscopy
Laryngoscope blades in multiple sizes and
configurations
Several handles, extra batteries
Oxyscope (Heine Optotechnik, D-82211
Herrsching)
Laryngeal mask airways
All sizes 1.0 to 6.0
ProSeal LMAs for patients with a full stomach or
those who require higher peak inflation pressure
for successful ventilation
Large-volume syringes for the larger masks
Fiberoptic intubation
Fiberoptic scopes—several sizes, including one
that will fit through a 2.5-mm ID endotracheal
tube
Light source
Teeth protectors
Oral airways designed for fiberoptic intubation
Silicon lubricant
21. Systemic Examination
Cardiovascular System :
Features of cardiac murmurs
Innocent Pathological
o Asymptomatic Symptomatic
o Soft Loud
o Early systolic Pan or late systolic, diastolic
Continuous
o No thrill Thrill present
o Disappears with positioning
o May be a venous hum
22. Clinical Features of Congestive Cardiac Failure :
Tachypnea, Sweating, Hepatomegaly
25. LABORATORY INVESTIGATONS
For minor procedure – In healthy children
Hb%/Urine/ BT-CT
For major procedure – Haematological
profile/urine/X-ray-Chest/S.Electrolytes/BUN/S.
creatinine
Random Blood Sugar – In adolescent patients
2D echo / Echocardiography – should be done if
murmur is present or suspect CHD
Other investigations like renal and hepatic function
tests etc., should be done if systemic diseases are
present
26. ASA CLASSIFICATION
Class I: Healthy patient, no systemic disease
Class II: Mild systemic disease with no functional
limitations (mild chronic renal failure, iron deficiency
anaemia, mild asthma)
Class III: Severe systemic disease with functional
limitations (hypertension, poorly controlled asthma or
diabetes, congenital heart disease, cystic fibrosis)
Class IV: Severe systemic disease that is a constant threat
to life (critically and/or acutely ill patients with major
systemic disease)
Class V: Moribund patients not expected to survive 24 hr,
with or without surgery
add “E” for —emergency surgery
27. INFORMED CONSENT
Consent should be obtained from the parent or
guardian for a paediatric patient, while explanation
and discussion should involve the patient’s next-of-
kin if the patient himself/herself is in no condition to
provide consent for treatment.
30. PREPARATION
Paediatric Sedation :
Psychological preparation and premedication are
much needed in paediatric patients. Infants more
than 6 months do resent separation from parents
and it is advisable to either have the parent hold the
child for “stealing with inhalational induction”.
31.
32. Venous access should be secured under topical local
anaesthetic cover.
The commonly used drugs to avoid separation
anxiety are Midazolam and Ketamine. An attractive
alternative is transmucosal Fentanyl and oral
Clonidine. Routine use of atropine as a premedicant
is not recommended nowadays.
Atropine/Glycopyrrolate has only specific
indications like tonsillectomy, cleft lip and palate,
difficult intubation or when secretogogues like
ketamine are used.
38. PREPARARTION
TEMPERATURE CONTROL:
Due to their small size with increased body surface area to
body weight ratio and increased thermal conductance, infants
and young children are at significant risk for thermal
instability.
The minimal ability to shiver during the first 3 months of life
makes cellular thermogenesis (metabolism of brown fat) the
principal method of heat production.
Important to address all aspects of possible heat loss during
anesthesia, as well as during transport to and from the
operating room.
Placing the baby on a warming mattress and warming the
operating room (80°F or warmer) reduce heat lost by
conduction.
39. Keeping the infant in an incubator, covered with blankets,
minimizes heat lost through convection. The head should also
be covered.
Heat lost from radiation is decreased with the use of a double-
shelled Isolette during transport. Heat lost through
evaporation is lessened by humidification of inspired gases,
the use of plastic wrap to decrease water loss through the skin,
and warming of skin disinfectant solutions.
Hot air blankets are the most effective means of warming
children.
Anesthetic agents can alter many thermoregulatory
mechanisms, particularly nonshivering thermogenesis in
neonates.
40. Risk is higher for premature infants and infants who
are small for gestational age.
Although awake infants are able to maintain
normothermia, they can do so only within a narrow
range of ambient temperatures and only for a limited
amount of time.
Exposure to the operating room with its normally
low ambient temperature combined with the high
airflow from the air-conditioning system during
anaesthesia and surgery, and the use of cold
infusions and dry anaesthetic gases can easily
overwhelm the thermal homeostatic mechanisms
and result in potentially serious complications.
41. Hypothermia-related complications include increased
morbidity, surgical wound infections, coagulopathies,
increased allogenic transfusions, negative nitrogen
balance, delayed wound healing, delayed postoperative
anaesthetic recovery, prolonged hospitalization,
shivering, and patient discomfort.
Prevention of Hypothermia is crucial. Operating room
temperatures of 27° and 29° C are recommended for full
term and premature newborns, respectively.
Other measures of preventing hypothermia include use
of radiant heaters, reflecting blankets, skin surface
warming blankets, warming matresses, humidified and
heated gases and warming of intravenous fluids.
45. Careful assessment of dehydration and accordingly
correction should be done with:
50ml/kg IV Fluids for mild dehydration
100ml/kg for moderate
150ml/kg IV fluids for severe dehydration.
46. CONCLUSION
Paediatric assessment and preparation is always a
challenging subject and more with learning students.
Hence considering all above mentioned points may
help and also it’s now become a super speciality so
that further study is always recommended.