Tonsillectomy is the surgical removal of the palatine tonsils. It is indicated for recurrent throat infections, tonsillitis causing medical issues, or enlarged tonsils obstructing breathing.
Pre-operative assessment involves evaluating the patient's medical history, examining the throat, and in some cases checking coagulation or doing a sleep study. Certain conditions like bleeding disorders or Down syndrome require special pre-operative management.
The surgery involves using various techniques like dissection and snare to separate the tonsils from surrounding tissue and remove them. Post-operative care focuses on pain management, diet, hygiene and watching for potential complications like bleeding or infection. Newer techniques aim to reduce morbidity through less invasive procedures
Foreign bodies refer to any object that is placed in the ear, nose, or mouth that is not meant to be there and could cause harm without immediate medical attention.
Foreign bodies refer to any object that is placed in the ear, nose, or mouth that is not meant to be there and could cause harm without immediate medical attention.
Disease of the nasal septum can cause nasal obstruction, excessive nasal discharge, epistaxis, headache and sinusitis. The diseases could be deviated nasal septum, septal haematoma, septal abscess and septal perforation. All these complaints are treatable.
Disease of the nasal septum can cause nasal obstruction, excessive nasal discharge, epistaxis, headache and sinusitis. The diseases could be deviated nasal septum, septal haematoma, septal abscess and septal perforation. All these complaints are treatable.
Managing Upper airway problems in children for ENT / Paediatric / Anaesthetic...MTD Lakshan
Here I discuss approach to managing an obstructed upper airway of a child. Details about clinical assessment, investigations and management stratergies are outlined.
The neonatal bowel obstruction is suspected based on polyhydramnios in utero, bilious vomiting, failure to pass meconium in the first day of life, and abdominal distension.The presentations of NBO may vary. It may be subtle and easily overlooked on physical examination or can involve massive abdominal distension, respiratory distress and cardiovascular collapse.Unlike older children, neonates with unrecognized intestinal obstruction deteriorate rapidly.
Neonatal bowel obstruction is grouped into two general categories: high, or proximal, obstruction and low, or distal obstruction, both of which are suspected by failure to pass meconium at birth. High obstruction can be suspected based on the double bubble sign. Cases without distal gas are usually related to duodenal atresia, while high obstruction with distal gas need an upper gastrointestinal series because of the need to distinguish duodenal web, duodenal stenosis and annular pancreas from midgut volvulus, the latter being a surgical emergency. Confirmation is ultimately by surgical intervention.
Jejunal and ileal atresia are caused by in utero vascular insults, leading to poor recanalization of distal small bowel segments, a condition in which surgical resection and reanastamosis are mandatory. Hirschsprung disease is due to an arrest in neural cell ganglia, leading to absent innervation of a segment distal bowel, and appears as a massively dilated segment of distal bowel on contrast enema. Surgical resection is necessary for this condition as well. Imperforate anus also requires surgical management, with the diagnosis made by inability to pass the rectal tube through the anal sphincter.[6] Supportive intravenous hydration, gastric decompression, and ventilatory support may be needed due to poor neonatal nutrition resulting from dysfunctional bowel absorption.
A low obstruction is suspected on plain film, but needs follow up with a gastrografin enema, which itself can be therapeutic. The differential for low obstruction is ileal atresia, meconium ileus, meconium plug syndrome and Hirschsprung disease. In cases of meconium ileus or ileal atresia, the colon distal to the obstruction is hypoplastic, usually less than 1 cm in caliber, as development of normal colonic caliber in utero is due to the passage of meconium, which does not occur in either of these conditions. When diffusely small caliber is seen, it is referred to as microcolon. Radiographs in meconium ileus classically demonstrate a bubbly appearance in the right lower quadrant due to a combination of ingested air and meconium. If, on contrast enema, reflux into the dilated distal small bowel loops can be achieved, the study is both diagnostic and therapeutic, as the ionic contrast medium can dissolve the meconium to allow passage of enteric content into the unused colon.
If contrast cannot be refluxed into the distal small bowel, ileal atresia remains a diagnostic possibility.
With early intervention, morbidity and mortality.
ANESTHETIC MANAGEMENT OF TRACHEOESOPHAGEAL FISTULA by Dr.Sravani VishnubhatlaDrSravaniVishnubhatl
Learning Objectives:
Review the clinical presentation of a patient with tracheoesophageal fistula (TEF)
Understand the prevalence of TEF, types, and associated syndrome
Discuss the diagnosis of TEF
Describe the medical and surgical management of TEF
Understand the anesthetic-related implications and develop an anesthetic plan
Tracheo oesophageal atresia and fistula A-Z for medical students
This powerpoint covers everything you need to know about tracheoesophageal fistula and atresia as a medical student.It is not intended for patients. Covers anatomy, embryology,types ,classification and treatment of tracheo-oesophageal fistula and atresia.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
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These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
3.
DIVIDED INTO 3:
1.ABSOLUTE.
2.RELATIVE.
3.AS A PART OF ANOTHER OPERATION.
INDICATIONS OF TONSILLECTOMY
4.
Recurrent infections of the throat. Paradise et al
> 7 ep. In 1 year or
5 ep. / year for 2 years or
3 ep. / year for 3 years or
>2 weeks of lost school or work in 1 year
Clinical features of each episode
Fever
Lymphadenopathy
Tonsillar/pharyngeal exudate
Positive-hemolytic streptococcus test
Medically treated
1.ABSOLUTE
5.
Peritonsillar abscess.
Tonsillitis causing febrile seizures.
Hypertrophy of tonsils causing
-airway obstruction
-difficulty in deglutition.
-interference with speech.
Suspicion of malignancy:
unilaterally enlarged tonsil
(Lymphoma in children/epidermoid ca in adult)
Cont…
6.
Diptheria carriers who do not respond to antibiotics.
Streptococcal carriers, who may be source of
infection to others.
Chronic tonsilltis with bad taste or halitosis which is
unresponsive to medicines.
Recurrent strep tonsillitis in pts with valvular heart
disease.
2.RELATIVE
7.
Palatopharyngoplasty which is done for sleep
apnoea syndrome.
Glossopharyngeal neurectomy.
Tonsil is removed first and then IX nerve is severed in the
bed of tonsil.
Removal of styloid process.
3.AS A PART OF OTHER
OPERATION
8.
Hb level less than 10 g%.
Presence of a/c infection in URI.
Children under 3 yrs of age.
Overt or submucous cleft palate.
Bleeding disorders eg:leukemia, hemophilia...
At the time of epidemic of polio.
Uncontrolled systemic diseases.
During the period of menses.
CONTRAINDICATIONS
14.
B –
potential CI e.g velopharyngeal,hematologic or
infection
Condition with increasing risk for postponing the
surgery e.g acute pharyngitis,fever,cough and
wheeze
C – management of pre -operative anxiety and
postoperative pain discussed with the patient and
family
16. Hematologic
Family or past history for unusual bleeding &
bruising
AAO-HNS & SFORL ; lab. Study indicated only
when the pt. or family hx is suggestive
Family hx is unavailable
Lab .studies ; PT, aPTT,INR, PLATLATE COUNT,
BT
Studies reveal that preoperative evaluation of coagulation
profile is NOT effective in identifying children who will
have post op. hg and it is NOT cost effective
17. Cardiac evaluation
Otherwise healthy children do not require a preoperative
cardiac evaluation for tonsillectomy and/or adenoidectomy
(T&A).
PSG & airway
A 2011 guideline recommends PSG in children who are
obese, have Down syndrome, craniofacial abnormalities,
neuromuscular disorders, sickle cell disease, or
mucopolysaccharidoses.
The PSG useful in ;
Level of post op. Care and the need for post op. oxymetry
Postponing or avoiding surgery
When the parental hx and physical ex. Are discordant
18.
Bleeding disorders
VWD and platelet function defect leads to increasing
perioperative hg.
Post op. hg in mild vwd who receive prophylactic
intervention can approach those unaffected
Autosomal dominant bleeding disorder
Increased bleeding time and prolonged aPTT.
Perioperative management
o IV Desmopressin (0.3ugm/kg)
o Serum Sodium
Pre-operative care in
specific condition
19.
Sickle cell disease
Risk for pain crisis ,acute chest syndrome, priapism and
strok if they became hypoxic ,acidotic or hypovolemic
during perioperative period
Pead.heamtologist included in periop. Period
To solve ;
Preoperative blood transfusion
Preoperative hydration
Preop. PSG
20.
Down syndrome
Risk of anaesthia related comp. due to soft and
skeletal alterations
OSA is common with DS so requir PSG
Increasing risk of delayed hospital stay due to
pulmonary comp.
Possibility of delayed oral intake
21. Emotional and pain preparation
Anxiety leads to increase post op. pain experience
So decrease in anxiety leads to decrease in post op.
pain
A prospective study of 241 children aged 5-12 yrs
who undergoes T&A surgery shows
More anxiety=
More postop. Pain
More consumption of pain medication
Hi incidence of delirium after op.
Hi post op. anxiety and sleep problem
22.
Other Tests
Antibodies for streptolysin-O (ASLO) have been
studied as possible indicators for tonsillectomy. [2]
These antibodies are correlated with previous
infection with group A beta-hemolytic streptococcus
(GABHS)..
When the diagnosis of recurrent GABHS is
questioned, high ASLO titers can shed light on the
patient's history.
23.
Imaging Studies
Imaging studies include plain radiography, CT
scanning, and MRI in an appropriate patient with a
tonsillar mass suggestive of malignancy.
In addition, a patient with a pulsatile area adjacent to
the tonsil should undergo magnetic resonance
arteriography (MRA) before routine tonsillectomy to
evaluate for an aberrant internal carotid artery.
24.
Histologic Findings
Histologic examination of the tonsils is unnecessary
unless cancer is suspected. If tonsils are asymmetric,
they should be submitted separately and examined
histologically to rule out cancer.
25.
Evaluation for allergy
Several studies have shown a higher-than-expected
incidence of allergy in children with adenotonsillar
disease. Therefore, evaluation for allergy may be
helpful, but only in children with the signs and
symptoms of allergic disease.
26.
Anaesthesia
The total duration of anesthesia should be as brief as is
practicable, certainly less than 30 minutes.
Total intravenous anesthesia with propofol and
remifentanil is associated with fast 'wake up' and little
'hangover
Propofol has the added merit of being an antiemetic agent.
perioperative
27.
Steroid therapy
single intravenous dose of dexamethasone was an effective,
relatively safe and inexpensive treatment for;
reducing morbidity from pediatric tonsillectomy.
an antiemetic.
Many units use a single dose of 2-4 mg
Cont..
32.
Boyle-Davis mouth gag is introduced and
opened.It is held in place by Draffins bipods or a string
over a pulley.
STEPS OF OPERATION
(DISSECTION AND SNARE
METHOD)
33.
Tonsil is grasped with tonsil holding forceps and pulled medially.
Incision is made in the mucous membrane where it reflects from
the tonsil to anterior pillar.
A blunt curved scissors may be used to dissect the tonsil from
the peritonsillar tissue and seperate its upper pole.
The tonsil is held in the upper pole and traction applied
downwards and medially.Dissection is continued until lower pole is
reached.
Wire loop of tosillar snare is threaded over the tonsil on to its
pedicle, tightened and the pedicle cut and tonsil removed.
A guaze is placed in the fossa and pressure applied for few mnts.
Bleeding points are tied with silk.
Procedure is repeated on the other side.
34.
IMMEDIATE GENERAL CARE
-keep the patient in coma position until fully recovered
from anesthesia.
- keep a watch on bleeding from nose and mouth.
-keep check on vitals ie pulse,BP,and RR.
POST OP CARE
35.
Diet
-after fully recovered; cold milk or icecream.
-sucking of ice cubes gives relief from pain.
-gradually from soft to solid food.
-plenty of fluids should be encouraged.
36.
Oral hygeine
-Pt is given Condy’s or hot water gargles 3-4 times a
day.
-Mouth wash with plain water after every feed.
Analgesics
-Pain, locally in the throat and reffered to ear can be
relieved by analgesics like paracetamol.
Antibiotics
-A suitable antibiotic can be given orally or by injection
for a week
37.
COMPLICATIONS
EARLY
•Primary h’ge(0.56%)
•Reactionary h’ge!!!!
•Injury to tonsillar
pillars,uvula,soft
palate,tongue or superior
costrictor muscle.
•Injury to teeth
•Aspiration of blood.
•Facial oedema.
DELAYED
•Secondary h’ge.(16.8%)
•Infection
(halitosis+fever)
•Lung complications
•Scarring in soft palate
and pillars.
•Tonsillar remnants.
•Hypertrophy of lingual
tonsil
39.
• Koltai et al, 2002
• Microdebrider at 1500 rpm in oscillating mode
• Hemostasis with suction cautery
Tonsil capsule is not violated thereby
avoiding pharyngeal muscle exposure to
secretions, injury, and inflammation As a
result, postoperative pain and recovery
time reduced
tonsillar regrowth with snoring
Intracapsular Tonsillectomy
40.
• Ultrasonic dissector and coagulator
• Vibratory energy
• Cutting: sharp blade with frequency of
55.5kHz
• Temp. of surrounding tissue is 80
• Coagulating: vibration breaks H-bonds,
thermal energy
Harmonic Scalpel Tonsillectomy
41.
No significant difference in intraoperative blood loss and postoperative
ability to eat and drink
Level of activity for the first postop day significantly lower in harmonic
scalpel group
Postoperative pain scores tended to be lower in harmonic scalpel
group
Willging et al
42.
• Kothari et al, 2002K
• KTP laser provides little benefit over dissection tonsillectomy
except to minimize intraoperative bleeding
higher postop pain scores
greater difficulty resuming postoperative diet
More risk for secondary bleeding
Limitations
• Technical expertise
Laser Tonsillectomy
43.
COBLATION TONSILLECTOMY
Technology combines radiofrequency
energy and saline to create a plasma
field. The plasma field remains at a
relatively low temperature 40-70°
as it precisely ablates the targeted tonsil
tissue.
The COBLATION plasma field
removes target tissue while minimizing
damage to surrounding areas.
The probes or 'wands' are single use
and there is a cost consideration
Haemorrhage' was defined as a bleed
that prolonged the patient's hospital stay, required blood
transfusion, a return to the operating theatre, or in the
case of 'secondary' haemorrhage readmission to hospital.