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This document discusses opioid analgesics, specifically morphine. It provides details on the classification, pharmacology, pharmacokinetics and adverse effects of morphine. Morphine is derived from opium extracted from the poppy plant. It acts primarily as an agonist at mu opioid receptors in the central nervous system to produce analgesia, sedation, euphoria and other effects. It has a wide distribution and undergoes extensive first-pass metabolism primarily through glucuronidation. Common adverse effects include sedation, constipation, respiratory depression and vomiting.














































