This document provides an overview of Microsoft Office 365 Data Loss Prevention (DLP). It defines DLP as a practice to protect sensitive data from loss or sharing. It describes how Office 365 DLP works by detecting sensitive content, defining policies to monitor activities, and taking protective actions. It also outlines how to configure DLP policies by specifying monitoring targets, locations, conditions, and actions. Finally, it discusses best practices for planning, preparing, testing and deploying DLP policies within an organization.