This document provides an overview of the steps to configure a Data Loss Prevention (DLP) policy in Office 365: 1. Create a new DLP policy and give it a name and description. 2. Choose the locations to include or exclude such as specific sites or users' OneDrives. 3. Configure the policy settings including whether to block or allow sensitive information types and what actions to take if sensitive info is detected, such as blocking access. Advanced settings allow creating custom rules. 4. Turn the policy on or off immediately and review before closing. Custom expressions can also be created to match specific content formats not covered by the default templates.