Odontogenic myxoma is a benign mesenchymal lesion resembling dental pulp or follicular connective tissue, primarily affecting individuals aged 10 to 50 years with no gender preference. Clinically, it presents as a radiolucent, well-circumscribed or diffuse lesion that may show a honeycomb pattern, while histopathologically, it consists of acellular myxomatous connective tissue with benign fibroblasts, myofibroblasts, and scattered capillaries. It can lead to cortical plate expansion, as well as root displacement or resorption.

1. ODONTOGENIC
MYXOMA
DR AMITHA G
DEPT OF ORAL AND MAXILLO FACIAL PATHOLOGY

2. ODONTOGENIC MYXOMA :
• Benign mesenchymal lesion that mimics microscopically the dental pulp or follicular
connective tissue
• Derived from odontogenic ectomesenchyme

3. Clinical feature:
• Age : 10- 50 yrs with mean age of 30 yrs
• No gender predilection
• Both mandible and maxilla are equally effected

4. Radiographic feature :
• Radiolucent and it appear as a well
circumscribed or diffuse lesion
• Often multilocular with honey comb pattern
• Cortical plate expansion, root displacement
or resorption may be seen

5. Histopathology :
• Tumor consist of acellular myxomatous
connective tissue.
• Benign fibroblast and myofibroblast with
some amount of collagen are found in matrix
• Bony island representing residual tubeculae
• Capillaries are scattered through out the lesion