The document outlines the agenda for the Northern Innovation and Networking Event 2017 on the adoption and spread of innovation. The event will include presentations on topics such as the importance of innovation, AHSN commercial support for SMEs, and case studies of innovations. Speakers will discuss the AHSN network and its role in improving health and supporting economic growth. The event aims to provide information to help health and life sciences SMEs engage with AHSNs and the NHS to drive the adoption and spread of innovations.
Let us share with you our successes, impacts and performance over the past year. The Innovation Agency is proud to bring you our Annual Report for 2015/16.
Harness digital platforms to accelerate R&D and drive proper adoptionSharpBrains
Pioneers in education, medicine and pharma discussed new data-rich approaches to help assess what works and what doesn’t, and for whom, accelerating R&D initiatives and proper adoption.
--Chair: Alvaro Fernandez, CEO & Editor-in-Chief of SharpBrains
--Richard Varn, Director of the Center for Advanced Technology and Neuroscience at Educational Testing Service (ETS)
--Dr. Brian Iacoviello, Director of Scientific Affairs at Click Therapeutics
--Dr. Gahan Pandina, Senior Director, Venture Leader at Janssen Research & Development
--Dr. Sarah Banks, Head of Neuropsychology at the Cleveland Clinic Lou Ruvo Center for Brain Health
Learn more at sharpbrains.com
Energesse and Palladium Executive Breakfast Series.
The healthcare ecosystem is becoming increasingly complex and consumer/patient needs and expectations are escalating. The drive to create a more sustainable healthcare system means that industry players are forced to deliver new models of care whilst developing more sustainable business models under ever more stringent budgetary conditions. As cost cutting and reengineering efforts reach diminishing returns, it has become obvious that the solution to this complex set of issues is to reframe the problem, working backwards from patients and health consumers to build models that deliver compelling experiences to consumers/patients and superior societal health outcomes.
Let us share with you our successes, impacts and performance over the past year. The Innovation Agency is proud to bring you our Annual Report for 2015/16.
Harness digital platforms to accelerate R&D and drive proper adoptionSharpBrains
Pioneers in education, medicine and pharma discussed new data-rich approaches to help assess what works and what doesn’t, and for whom, accelerating R&D initiatives and proper adoption.
--Chair: Alvaro Fernandez, CEO & Editor-in-Chief of SharpBrains
--Richard Varn, Director of the Center for Advanced Technology and Neuroscience at Educational Testing Service (ETS)
--Dr. Brian Iacoviello, Director of Scientific Affairs at Click Therapeutics
--Dr. Gahan Pandina, Senior Director, Venture Leader at Janssen Research & Development
--Dr. Sarah Banks, Head of Neuropsychology at the Cleveland Clinic Lou Ruvo Center for Brain Health
Learn more at sharpbrains.com
Energesse and Palladium Executive Breakfast Series.
The healthcare ecosystem is becoming increasingly complex and consumer/patient needs and expectations are escalating. The drive to create a more sustainable healthcare system means that industry players are forced to deliver new models of care whilst developing more sustainable business models under ever more stringent budgetary conditions. As cost cutting and reengineering efforts reach diminishing returns, it has become obvious that the solution to this complex set of issues is to reframe the problem, working backwards from patients and health consumers to build models that deliver compelling experiences to consumers/patients and superior societal health outcomes.
Best practices to fund, develop and commercialize evidence-based innovationSharpBrains
In this session we discussed key lessons learned for scientists and start-ups to successfully bring to market evidence-based innovative solutions. We will also present non-dilutive funding opportunities and commercialization resources offered through the US small business research programs. A scientist and inventor turned serial entrepreneur will wrap-up the day sharing insights from his previous venture–funded by the NIMH and sold to McKesson–and his current strategy and vision.
--Chair: Dr. Alison Fenney, Executive Director of the Neurotechnology Industry Organization
--Dr. Margaret Grabb, SBIR/STTR Program Director at the National Institute of Mental Health (NIMH)
--Dr. Rex Jakobovits, Founder of Vivalog Technologies and Experiad
Learn more at sharpbrains.com
Expo Day: Bridge Builders Collaborative, American Academy of Clinical Neurops...SharpBrains
During Expo Day selected Summit Partners and Sponsors showcased their latest initiatives and solutions.
--Charlie Hartwell, Operating Partner at The Bridge Builders Collaborative, delivered an Overview of the Mind Training Space.
--Dr. Bob Bilder, Chief of Medical Psychology & Neuropsychology at UCLA, announced the Disruptive Technology Initiative by the American Academy of Clinical Neuropsychology (AACN).
--Ron Riesenbach, Managing Director of the Canadian Centre for Aging and Brain Health Innovation (CC-ABHI), presented Spark and three other new funding programs.
Learn more at sharpbrains.com
Using Technology to Lower Costs & Delight CustomersBJ Hoffpauir
This presentation outlines the challenges facing manufacturers, distributors, retailers and ultimately Consumers of Health Care Products - particularly those in need of Durable Medical Equipment (DME) Supplies and Products like Breast Pumps.
With the passage of the Affordable Care Act, every participant in the Health Care Product, Service, and Delivery value chain is facing increased competition in the marketplace while simultaneously being pressured from both Consumers, Government and Insurance Providers to reduce costs, profits and waste.
It's an incredibly difficult challenge for even the most Agile and nimble startups that are well funded from Venture Capital Investors or Private Equity Groups, but for the established participants in the the DME Marketplace, many of whom are over 100 years old, some of the oldest companies in America, adapting quickly to changing market environments is not a capability they have ever developed. Many of these markets are heavily regulated and the ACA was the first major change to some of those markets in 50+ years.
This presentation discusses how ACA Ventures, owner and operator of some of the most successful retail and wholesale distributors of Breast Pumps and Breast Feeding Accessories and Supplies in the USA went from it's first order to becoming a national innovator leading the market in customer service and technological innovation based on Open Source technology like Magento and a commitment to agile principles, customer service and delivering real value to every one of its partners and customers in the value chain of their market.
The Other Side of Wireless - Connecting Medical Devices with Mobile, Cloud Co...Orthogonal
Discussion of the market opportunities, engineering and regulatory challenges, as well as approaches for building systems that incorporate medical devices, diagnostics and sensors with mobile, cloud computing and analytics to deliver solutions for improved health outcomes. Areas of opportunity include remote patient monitoring, early detection and prevention, extending therapies outside of a clinical environment, adherence for medication and other therapies, as well as management of chronic conditions and perioperative management.
Presentation by Bernhard Kappe at MD&M East 2014 in New York on June 9th, 2014
Presentations by Mike Kenny, Acting Co-Director of Enterprise and Growth, Innovation Agency and Dr Neil Paul, a GP and Board Member with Cheshire East ICP at the Excel in Health: Understanding the NHS Landscape webinar on Wednesday 11 May 2022.
Putting innovation into practice (NHS vs Widnes Vikings)Richard Harding
Where is the Front Door to the NHS?
How do we procure innovation and innovate procurement in Health?
What does health want?
How does an SME leverage Local Infrastructure
Best practices to fund, develop and commercialize evidence-based innovationSharpBrains
In this session we discussed key lessons learned for scientists and start-ups to successfully bring to market evidence-based innovative solutions. We will also present non-dilutive funding opportunities and commercialization resources offered through the US small business research programs. A scientist and inventor turned serial entrepreneur will wrap-up the day sharing insights from his previous venture–funded by the NIMH and sold to McKesson–and his current strategy and vision.
--Chair: Dr. Alison Fenney, Executive Director of the Neurotechnology Industry Organization
--Dr. Margaret Grabb, SBIR/STTR Program Director at the National Institute of Mental Health (NIMH)
--Dr. Rex Jakobovits, Founder of Vivalog Technologies and Experiad
Learn more at sharpbrains.com
Expo Day: Bridge Builders Collaborative, American Academy of Clinical Neurops...SharpBrains
During Expo Day selected Summit Partners and Sponsors showcased their latest initiatives and solutions.
--Charlie Hartwell, Operating Partner at The Bridge Builders Collaborative, delivered an Overview of the Mind Training Space.
--Dr. Bob Bilder, Chief of Medical Psychology & Neuropsychology at UCLA, announced the Disruptive Technology Initiative by the American Academy of Clinical Neuropsychology (AACN).
--Ron Riesenbach, Managing Director of the Canadian Centre for Aging and Brain Health Innovation (CC-ABHI), presented Spark and three other new funding programs.
Learn more at sharpbrains.com
Using Technology to Lower Costs & Delight CustomersBJ Hoffpauir
This presentation outlines the challenges facing manufacturers, distributors, retailers and ultimately Consumers of Health Care Products - particularly those in need of Durable Medical Equipment (DME) Supplies and Products like Breast Pumps.
With the passage of the Affordable Care Act, every participant in the Health Care Product, Service, and Delivery value chain is facing increased competition in the marketplace while simultaneously being pressured from both Consumers, Government and Insurance Providers to reduce costs, profits and waste.
It's an incredibly difficult challenge for even the most Agile and nimble startups that are well funded from Venture Capital Investors or Private Equity Groups, but for the established participants in the the DME Marketplace, many of whom are over 100 years old, some of the oldest companies in America, adapting quickly to changing market environments is not a capability they have ever developed. Many of these markets are heavily regulated and the ACA was the first major change to some of those markets in 50+ years.
This presentation discusses how ACA Ventures, owner and operator of some of the most successful retail and wholesale distributors of Breast Pumps and Breast Feeding Accessories and Supplies in the USA went from it's first order to becoming a national innovator leading the market in customer service and technological innovation based on Open Source technology like Magento and a commitment to agile principles, customer service and delivering real value to every one of its partners and customers in the value chain of their market.
The Other Side of Wireless - Connecting Medical Devices with Mobile, Cloud Co...Orthogonal
Discussion of the market opportunities, engineering and regulatory challenges, as well as approaches for building systems that incorporate medical devices, diagnostics and sensors with mobile, cloud computing and analytics to deliver solutions for improved health outcomes. Areas of opportunity include remote patient monitoring, early detection and prevention, extending therapies outside of a clinical environment, adherence for medication and other therapies, as well as management of chronic conditions and perioperative management.
Presentation by Bernhard Kappe at MD&M East 2014 in New York on June 9th, 2014
Presentations by Mike Kenny, Acting Co-Director of Enterprise and Growth, Innovation Agency and Dr Neil Paul, a GP and Board Member with Cheshire East ICP at the Excel in Health: Understanding the NHS Landscape webinar on Wednesday 11 May 2022.
Putting innovation into practice (NHS vs Widnes Vikings)Richard Harding
Where is the Front Door to the NHS?
How do we procure innovation and innovate procurement in Health?
What does health want?
How does an SME leverage Local Infrastructure
Presentation by Mike Kenny, Associate Commercial Director, Innovation Agency: The NHS Landscape at Excel in Health: understanding the NHS as a market place on Tuesday 26 February 2019 at Vanguard House, Daresbury.
Karen Livingstone - ECO 17: Transforming care through digital healthInnovation Agency
Presentation by Karen Livingstone, Director of Innovation Exchange and SBRI Healthcare, NHS England: Transforming Health and Social Care Services - The Innovation Exchange and SBRI Healthcare at ECO 17: Transforming care through digital health on Tuesday 4 December at Lancaster University, Lancaster
New Funding & Development Opportunities for InnovatorsIsabelle Sparrow
On November 8th GM AHSN invited innovators from the region to an event at the Nowgen Centre in Manchester. The event provided information about some of the current funding and support opportunities available to healthcare innovators, including programmes from GM AHSN's Innovation Nexus, SBRI Healthcare and the Business Growth Hub.
Executive Healthcare Seminar - Belgium - Saudi Arabia - Belgian Embassy RiyadhJan Demey
Belgian and Saudi Healthcare executives met in the Belgian Embassy to discuss several topics in the evolving healthcare market and the Vision 2030 of the Kingdom of Saudi Arabia. The ambition to work together to make healthcare better is our joined ambition. This presentation brings the supporting ideas as discussed during the seminar.
By: Fiona Fitzgerald, GE Healthcare Canada
At Sherbrooke International Life Sciences Summit - 2nd edition | September 28/29/30 2015
www.sils-sherbrooke.com
Presentations by Tawfiq Choudhury and Rocco Hadland from the second webinar of the Mastering Cholesterol webinar series on Thursday 11 May 2023, focusing on Statins.
Targeting lipids: a primary and secondary care perspectiveInnovation Agency
Presentations by Dr Sue Kemsley and Dr Gavin Galasko from the first webinar of the Mastering Cholesterol webinar series on Thursday 26 January 2023, focusing on lipid management from a primary and secondary care perspective.
Supporting the optimal detection and management of BP in Primary CareInnovation Agency
Presentation by Jane Briers, Programme Manager - Innovation Agency at the Supporting recovery in Primary Care using Proactive Frameworks for Long Term Conditions event on Thursday 15 September 2022.
Presentation by Dr Lauren Moorcroft, GP Partner - Brookvale Practice at the Supporting recovery in Primary Care using Proactive Frameworks for Long Term Conditions event on Thursday 15 September 2022.
Introduction to Supporting recovery in Primary Care using Proactive Framework...Innovation Agency
Presentation by Julia Reynolds, Associate Director for Transformation - Innovation Agency at the Supporting recovery in Primary Care using Proactive Frameworks for Long Term Conditions event on Thursday 15 September 2022.
Presentation by Paul Brain, Project Manager at the Excel in Health series - Introduction to data webinar on Monday 6 June 2022.
In this session we discussed how SMEs can use data to grow their business and access new opportunities in the market.
LCR and Cheshire and Merseyside Health MATTERS networking eventInnovation Agency
Master slide deck from the LCR and Cheshire and Merseyside Health MATTERS networking event on Wednesday 24 November 2021 at Sci-Tech Daresbury Laboratory.
Master slide deck from the Excel in Health webinar series: The NHS landscape presentation.
This webinar identifies the structure of the NHS and its national priorities.
The session will cover the following topics:
Understand the structure of the NHS
Understand the national priorities of the NHS
Recognise the barriers to sale
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
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Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
6. Spread and adoption:
AHSN Commercial support
Mike Kenny,
Associate Commercial Director
Innovation Agency (AHSN for the NW Coast)
Mike.kenny@innovationagencynwc.nhs.uk
@innovation_mike 6
7. Spread and adoption:
AHSN Commercial support
The AHSN Network
Why Health & Life Sciences SMEs?
Innovation & Transformation = New Models of care &
reimbursement
AHSN Offer for driving Adoption & Spread
Good to know before you go “all in”
11. 11
• Health and Lifesciences employment >10% of UK GVA
• Aging population / rising demand = high growth
potential for employment/GVA
• Local and Regional Authorities targeting Health and Life
Sciences sector for infrastructure investment
• >60% of all employment in UK is via SMEs (0 to 249
employees)
• Over 99% of businesses are SMEs
• >85% of businesses supplying the NHS are SMEs
• NHS = £120 Bill sized Market / System
• Health & Care Market - £150 Bill in 2013…..
AHSNs, the NHS & SMEs
12.
13. The NHS is Brilliant at Innovation….
• Traditionally slow to adopt….
• Needs new approaches to support adoption
14. New Models of Care Programmes are challenging existing
methods of service design and reimbursement….
• Services will remain – e.g. AF, COPD
• Technology & Innovations enable them to become
Safer, Better, Faster, Cheaper
• Implementation requires clinicians & citizens to
change behaviour
– …for which professionals expect evidence
– …and which takes time
• Evidence ‘gold standard’ - medicines, RCT’s
• Apps, PoC Innovation, Digital Health – don’t fit into
traditional commissioning /procurement/
reimbursement “boxes”
• Need new approaches to support adoption
19. Some Tips for Engaging with AHSNs & NHS
• Funding – we are not organisations who can provide monies for product
development or commercialisation
• But we will provide support to access it
• We are not research organisations
• But we can provide access to those that are
• We are not a sales resource
• But we can help you build your NHS value proposition
• We can support access to key people – clinicians, commissioners,
procurement
We Are – a Critical Friend We Are – an Honest Broker
20. • Clarity – Have a clear focus– know what your “ask” is
• Understand - the Needs & Priorities of the NHS around your innovation
• Avoid the hard sell –understand what is in it for the NHS, Patients, Citizens
• Long Game – AHSNs can vastly speed up adoption by removing barriers, but
working with CCGs & Trusts requires a patient & controlled approach
• Co-create – the solution to the perceived problem you believe your
innovation solves for the NHS:
• Engage & Partner rather than Tell or Sell
• Understand through policy documents and plans/ procurement calls –
• How relevant your product is
Some Tips for Engaging with AHSNs & NHS
21. Some Tips for Engaging with AHSNs
and the NHS
• If you want to do business with the NHS – your local AHSN should be an
early port of call
• Before you engage with the NHS/AHSNs – conduct your own honest
appraisal of your innovative product
• Ask yourself – in the context of the NHS & Healthcare, is this product
Safer
Better
Faster
Cheaper
• The more of these boxes you can tick, the more likely your AHSN will be
able to help you
23. Innovation in the NHS:
Commercialisation process for Doncaster & Bassetlaw
Teaching Hospital NHS FT’s eNOF (Electronic Pathway for Neck
of Femur Fracture) Product
Stephen Taylor-Parker
Innovation Manager
Medipex
31. Identification of unmet need/problem
Potential benefits from proposed development
Financial – Increase BPT fee from £700 > £1,399
Clinical – Reduce Number of aborted Operations
Patient experience – Less time as in-patient
Development of Business Case
Scoping of project and management of development budget
Landscape survey of “Patent and Prior Art”
Created in depth market intelligence report
Involvement of Medipex at all Stages
Example based on 100 annual patient incidents (£)
Cost of manual data input 24,000.00
Annual software licence 15,000.00
Support and maintenance
@ 12.5% of licence fee 1,875.00
Cost Saving 7,125.00
Additional revenue by meeting
uplift guideline (50%) 69,995.00
Total revenue increase 77,075.00
Baseline revenue 100 x £700 70,000.00
Potential unit revenue £147,075.00
32. Support for inventor and development team
Regular Project meetings
Advice on MedDev regulations & CE marking
Liaison with Trust executive team on potential
commercialisation
Support for internal testing and Proof of Concept
Draft Non Disclosure Agreement for external discussions
Involvement of Medipex at all Stages
33. Commercialisation Process
Discussion options with Trust Exec team to agree
appropriate pathway
Trade sale
Direct sales via NHS
Licencing to 3rd party sales organisation
Partner with Medipex
Develop Sales and Marketing Business plan
Involvement of Medipex at all Stages
35. Appointment of Medipex by Trust for Sales and Marketing Activity
Draft Sales and Marketing Outsourcing Agreement
Identify and contract with external software support organisation
Draft Support and Maintenance Contract
Draft Sales Licence
Create targeted contact marketing database
Develop marketing collateral
Product fact sheet
Marketing brochure
Pop Up banners for exhibitions
Create product website incorporating enquiry capture and
response mechanism
Involvement of Medipex at all Stages
41. Cervix Visual Assessment Guide
Alison Roberts
Specialist Nurse Colposcopist
South Tees Hospitals NHS Foundation Trust
Last year’s business case winner….
42. Innovation and Production of A Cervix Visual
Assessment Guide
Sister Alison Roberts
Specialist Nurse Colposcopist
M.A. Grad.Dip. RGN
South Tees Hospital’s NHS Foundation Trust
43. CVAG Design
Assisting primary care professionals with the identification of symptoms and
(unaided) visual appearances. The CVAG is comprised of:
• A desktop booklet with multiple (unaided) images of the cervix typical of those
seen in a primary care environment.
• Clinical management and referral criteria reflecting guidelines from the
NHSCSP publication 20 (March 2016); PHE, Service Specification no.25 (2015)
and NICE
• Book and leaflet explaining use and learning outcomes
• The CVAG is designed for ease of accessibility in a clinical area and for ease
of use by the practitioners. Because of the infrequency of practitioners viewing
abnormal cervix, an unusual presentation of a normal cervix or benign condition,
may result in the patient being referred into a two week rule clinic.
44. Development and Objectives
• The concept was initiated and developed as project work for
MA Advancing Practice; Teesside University 2011-2014
• Designed to assist primary care health professionals with the
assessment and evaluation of the cervix
• To raise awareness of the signs, symptoms and appearance
of cervical cancer compared with the normal cervix and benign
cervical conditions
• To promote excellence in practice
45. Systematic way
Enabling Engaging
Evaluating
Patient
centredness
Professional accountability
Evidence base practice
Quality improvement
Outcome
Individual
Team
Organisational
Cultural Systems and
process
Governance principles
Change
Supporting
Practice development
Facilitating
Encouraging
Collaboration
Communication
Practice development: a framework for excellence in practice, McSherry & Warr, (2008)
Enlightening
Kotter’s 8 stage process of
creating major change
46. Innovation Scout Business Case
• £1000 Prize Competition October 2016
• Author time to update and complete CVAG v2 2017
• Application of ISBN
• Production and Printing Costs (1000 copies)
• Promotional Leaflets and Marketing through the LRI website
at: www.southteeslri.co.uk/innovation
• Educational Poster timed for official launch at BSCCP Annual
Scientific Meeting, Cardiff. (May 2017)
47.
48. Sales
• Costs per unit reflect the numbers ordered ranging from
£12.00 to £20.00 per copy.
• Sales figures from May-Sept - £5,940
• Numbers sold from May-Sept – 427
• Widespread distribution: England, Scotland, Northern Ireland
and Wales
• Bulk orders received from the North East Cervical Screening
Training Centre and Northumbria University
49. Future Developments
• Trust and University supported evaluation project
• Application for NICE Endorsement
• NHSCSP Endorsement
• Promotional educational video
• Development of an electronic CVAG
51. References
• Cervical Screening Programme, England. Statistics for 2013-14 V1.0, Health and Social
Care Information Centre (Nov, 2014) http://www.hscic.gov.uk/catalaogue/PUB15968 -
Accessed 8th January 2015
• Kotter, J.P. (1996) Leading Change. Boston, Massachusetts, Harvard Business Review
Press.
• Master of Arts Advancing Practice Programme Handbook, (2011), School of Health and
Social Care: Teesside University.
• McSherry, R. and Warr, J. (2008) An Introduction to Excellence in Practice Development in
Health and Social Care. Berkshire, England, Open University Press.
• NHS Cervical Screening Programme (2016) Colposcopy and Programme Management,
Guidelines for the NHS Cervical Screening Programme, Third Edition, NHSCSP
Publication No 20, Sheffield: NHSCSP.
• NICE Clinical Guideline No.27 (2011) Referral Guidelines for Suspected Cancer
www.nice.org.uk/nicemedia/pdf/cg027niceguideline.pdf - Accessed: 15th December 2012
52. Diffusion and Adoption of Innovation:
International perspectives on theory and practice
Dr Yasser Bhatti
Research Fellow in Frugal Innovation
Institute of Global Health Innovation
Imperial College London / Helix Centre
53. Diffusion and adoption of innovation:
International perspectives on theory
and practice
12 Oct 2017
Yasser.Bhatti@imperial.ac.uk
54.
55. Dr Greg Parston
Dr Matthew Harris
Dr Yasser Bhatti
Dr Matthew Prime
Jacqueline del Castillo
Nikitha Reddy
Hamdi Issa
Matthew Quinn
Kavian Kulasabanathan
Ibtehal Attaelmanan
Seema Yalamanchali
56. NEED IDEATIO
N
KNOWLE
DGE
PERSU
ASION
ADAPTI
ON
ADOPTI
ON
SCALIN
G
EVALUA
TION
Investigatin
g what
constitutes
a reverse
innovation
and
developing
a typology.
Investigatin
g, to what
extent
reverse
innovation
as a
construct
challenges
current
institutions
and
narratives.
Investigating whether
cognitive biases and
prejudices exist against
research or innovations
from low income countries.
Evaluating International
health partnerships, and
volunteers knowledge of
innovation in partnership
countries and its translation
in the UK.
WISH showcase – an
annual competition
which captures and
features underexposed
healthcare innovations
from around the world to
global experts.
Evaluating
the spread
and
diffusion of
reverse
innovation
by
analysing
the Center
for Health
Market
Innovation
s
database.
GDHI Phase
1 -
Investigated
the enablers
and frontline
behaviours
necessary for
successful
diffusion of
healthcare
innovations
through in-
depth
interviews
with
healthcare
experts and
a large scale
survey of
HCPs and
IPs.
GDHI Phase 2 -
Investigated eight
successful examples of
rapid
innovation diffusion around
the world to better
understand the facilitators
and enablers of healthcare
innovations.
GDHI Phase 3 –
Investigating curator
organisations and how
relevant the innovations
found are to peoples needs.
Exploring how grassroots
innovation, as a source of
frugal innovation, can be
directed at prevention and
wellness-oriented
outcomes.
The
developme
nt and
diffusion of
surgical
frugal
Innovation
s –
Lessons
for the
NHS
Impact of
research
source on
evidence
interpretatio
n – an
individual,
randomised
, controlled,
blinded trial
CWF:
Translating
Frugal
Innovation
s to the US
By
Identifying
and
evaluating
frugal and
reverse
innovations
in
healthcare
Social
movements
in
healthcare
and the
NHS
Co-design
and Open
innovation
for end of
life care
57. Big questions
• Sources (who, where)
– Who innovates?
– Where to find it?
• Process (how)
– How does it happen and diffuse?
• Outcomes (what).
– What does it do?
57
58.
59. GDHI 2015
Innovation
Phase 1
Create a climate
for change
Phase 2
Engage and enable
organisations to
implement change
Phase 3
Embed and sustain
the change
Transformation
Specific agent
for change
ICT
incentives
and Rewards
Specific
funding for
diffusion
Vision
strategy and
leadership
Transparency
of research
and data
Communication
channels
Standards
and
Protocols
Time and
space for
learning
Identify
champions
Delayering
Improving
the next
journey
Adapt to
local context
Engaging
patients and
the public
Address
concerns of
professionals
EnablersFrontlinebehaviours
Accelerating the journey: building organisational capacity for change
60. 60
2013 & 2015 GDHI findings about frontline
Making time
and space
for learning
and adopting
new ways of
working
Engaging the
public to
create social
demand for
innovation
61. Learning new ways in innovation
• Open Innovation
• Grassroots Innovation
• Reverse Innovation
61
73. 73
Literature
FHW &
Leaders
Top-down
hierarchical sourcing
Low – High
income
country
sourcing
High – Low
income
country
sourcing
Internal
sourcing
Bottom-up
hierarchical sourcing
External
sourcing
Reverse
innovation
Grassroots
innovation
Open
innovation
78. Reverse
Very little reverse innovation
appears to be taking place. Only
10 percent of FHWs report that
they source ideas from practice in
other countries.
79.
80. “Insanity is doing the
same thing over and over
again and expecting
different results.”
Albert Einstein
87. UK Key findings
• While concerns about quality and safety are relatively
low in England, FHWs cite challenges surrounding
the delivery of care and patient experience; particularly
integration between levels of care and the complexity
of the patient journey.
• Leaders also recognise these challenges, however
finances are the leading concern.
• FHWs in England tend to source new ideas from other
organizations in England, with only a small proportion
looking to other countries.
• FHWs in England almost exclusively name other HICs as
useful sources of innovation. They tend to look to
these countries due to their perceived similarities.
98. Status: ConfidentialIssue Date: 2-Mar-17
As well as the above, I’m…
- Speech and Language Therapist
- Clinical Lead in Telesolutions Blackpool
Teaching Hospitals NHS Foundation
Trust
- Digital Leader at NW STP
- Consultant to New Care Models
Programme
- Director Veronica Southern Telerehab
Ltd/ Teleswallowing Ltd
- Ideas generator and
implementer
- Proud dog owner
vstr.mybiz.org.uk
Who’s this??
Veronica Southern MA BSc MRCSLT
99. People Centred Positive Compassion Excellence
‘The Workplace of the Future:
it’s not where you go
but what you do’Hugh Bradlow, Chief Technology Officer, Telstra, Sept 2011
Winner: Clinician in
Informatics 2016
Veronica Southern MA BSc MRCSLT
101. Status: Confidential
…swallowing difficulties are prevalent among elderly…
Swallowing difficulties are prevalent among the elderly, are a
frequent corollary of neurological disease and are a predictor of
poor rehabilitation, increased hospital stay and poor outcome.
• 426,000 elderly and disabled people in residential care
• 50-75% of nursing home residents have dysphagia
• as population ages the NHS resources needed to provide early
identification, assessment and management will escalate.
National Clinical Guidelines for good practice already supports
early identification, assessment and management of dysphagia
Issue Date: 28-Aug-17
1
0
102. Status: Confidential
…and poses a challenge.
Assessment of care home residents’ swallowing by SLT requires:
• domiciliary visits by SLT which are an inefficient use of NHS time & resources
• attendance at out-patient clinics which require carer supervision, hospital
transport, inconvenience and stress for elderly and infirm patients and missed
appointments waste considerable NHS SLT time
Delays in the identification, assessment and management of
dysphagia due to staff shortages, work patterns and waiting lists may
cause:
• the deterioration of a care home resident’s health
• subsequent hospital admission
Issue Date: 28-Aug-17
1
0
104. Status: Confidential
The journey…….
Veronica Southern
30 years experience NHS
MA in Health Research
Innovation bids and development of
remote access for communication
disorders
the problem
Issue Date: 28-Aug-17
1
0
Liz Boaden
29 years experience NHS
PhD: improving the
identification and
management of aspiration
the problem
A rapid, cost-effective identification, assessment and
management of dysphagia
106. …an innovative use of technology that
significantly enhances the use of limited
NHS resources by reducing costs, saving
time, improving productivity and
increasing capacity while enhancing the
quality of care experienced by the
patient ...
The Teleswallowing video
tells the story…please tap my app
http://vstr.mybiz.org.uk
107. Status: ConfidentialIssue Date: 2-Mar-17
“I like the fast track. It
minimises the delay
of assessment and
implements a plan to
reduce distress to
patients and
residents”
Nurse
“Nursing Home staff have
increased knowledge
when they discuss clients
on the phone.
They are more
knowledgeable and
this makes the case
discussions
more effective and less
risky”
Speech and Language Therapist
“We thought there would
be a lack of personal
touch but we found that
this was not the case.”
Speech and Language
Therapist
108. Status: Confidential
Benefits realised from teleswallowing evaluation…
Removed the need for patients to receive a care home visit and none were
admitted to hospital
100% diagnostic accuracy for diet and fluid modification compared to bedside
assessment
79.5% reduction in cost per patient compared to home visits
98.5% reduction in cost per patient where early assessment and treatment by
Teleswallowing prevents deterioration in patient health and subsequent
admittance to hospital
66% reduction in time taken to assess each patient vs to home visits
50% reduction in time taken to assess each patient compared to bedside
assessment in hospital
Improved response time to referrals
Improved quality of service for patients and care homes
Issue Date: 28-Aug-17
1
0
109. Status: Confidential
It’s a clinical tool adding tangible value
Enabling faster access to patients before they deteriorate and require
costly hospital admission – reduce costly 999 calls from care homes
Triage and review tool which can monitor 3 people vs 1 home visit
Enables nurses in care homes to become more skilled in rehabilitating
their patients, e.g. positioning/feeding patients, improving resilience in
care homes
Reduction in home visits, increase in productivity - easier to slot in a 30
minute remote assessment than a 90 minute home visit
Reduce waiting lists
Remote training tool as well as a clinical tool (delivering programme of
dysphagia management and awareness)
Linking specialists to junior staff in the community
Issue Date: 28-Aug-17
1
0
110. Status: Confidential
Money, money, money…
Issue Date: 28-Aug-17
1
1
Cost of one home visit: £47.60 clinician
time + £21.15 travel time + £7.28 travel
cost = £76.03 vs one Teleswallowing
assessment = £15.87.
£60.16 saving per assessment
e.g. The saving from 500
Teleswallowing assessments (via a team
of different therapists increasing
patient throughput at the same
clinician rate of pay) =
£30,080 saving
111. Status: Confidential
London Speech and Language
Therapy and University College
London
Workforce Scoping Project
Phase 2:
modelling workforce
transformation example
Results:
The Teleswallowing model could
free up a total of 10.38 weeks SLT
time in one year, and 1.9 weeks
of care home staff time.
Issue Date: 28-Aug-17
1
1
1
112. Status: ConfidentialIssue Date: 28-Aug-17
1
1
New Care Models
Teleswallowing Ltd has been
successful in a bid to NHS
England New Care Models
Programme; Harnessing
Technology Investment Fund
Teleswallowing training is being
delivered in 100+ care homes in
the Fylde Coast Vanguard: Care
Home Connect
Also being used at Blackpool Teaching
Hospitals and Central Cheshire Integrated
Partnership
115. Status: ConfidentialIssue Date: 2-Mar-17
1
1
5
A Digital Practitioner prescribing digital solutions
www.healios.org.uk
Reimagining
psychological therapies
using technology
www.Salaso.com
Promoting self
management and
independence through an
online app
patient
Hands-on
Remote teaching
A Digital Practitioner prescribing digital solutions
Apps
Therapy software
116. Status: Confidential
Contact me now on my Digital Business Card!
Issue Date: 2-Mar-17
Open the web browser on your
phone and type the following web
address into the top field.
vstr.mybiz.org.uk
You can then save my card to your home screen as a button for
instant phone, text or email contact in the future.
Please contact me!
117. Using Technology to Improve Patient
Experience
Mark Simpson
Project Support Officer
Leeds Community
Healthcare NHS Trust
Iona Taylor
Dietetic Clinical Lead
Leeds Community
Healthcare NHS Trust
Mike Odling-Smee
Technical Director
Aire Logic
130. Established in 2007 – three main streams of
business, Consultancy, Development and
Product (forms4health) year on year growth
Involved in the definition of the national
interoperability approach, inc GP Connect,
Care Connect and Spine 2
Developed the recognised agile healthcare
enterprise architecture method EA Light, to
support organisations reviewing their ICT
and deliver an organisational ICT roadmap
for the future
forms4health now being used from Leeds to
the US
ABOUT AIRE LOGIC
131. Clinical electronic forms platform
capturing, presenting and graphing clinical
data
Nursing assessments, EoL care plan,
discharge summary, patient facing forms
and many more
Contain pre-population capability, skip
logic, calculations, lightweight decision
making support, input validation, business
logic
Building block approach to form
development, rapid design and
deployment – easy to replicate, proving
cheaper to deliver
THE forms4health SOLUTION
132. Structured data for business intelligence,
monitor, evaluate and report on the data
Working across a range of devices, iPad,
smartphone, android tablets
Scalable, small numbers of forms to EPR
Users can develop, edit and ‘withdraw’
forms
Can ‘gap fill’ for other solutions –
provision of solutions for existing system
gaps and full integration with existing
solutions
THE forms4health SOLUTION
133. A case study
LTHT – 13,000 users; 215,000+ forms
per month
40,000 handover documents preventing
accidental loss, and delivering
consistency of process and time for shift
handovers ‘markedly reduced’
90,000+ National Early Warning System,
e-obs forms per month – meeting
national standards
Primary Care Access Line – eForm
saves 4,000 pieces of paper per month
and removed fax referrals
forms4health IN NUMBERS
134. A case study
50-100 integrations achieved per
annum, from patient information
between systems to specialist
information to regional providers
Massive cost savings, the LCR efficiency
benefits alone were over £3 million
Unplanned patient list – forms4health
allowed £150k cost improvement,
reducing calls, faxes and administrative
time
Paper and ink saving £15,000 per month
forms4health IN NUMBERS
138. ePAQ
electronic Personal Assessment Questionnaire
Supporting healthcare with web-based instruments
12th October 2017, Leeds
Y&H AHSN Showcase
Stephen.Radley@sth.nhs.uk
Gynaecologist & Director of Research
Jessop Wing, Sheffield Teaching Hospitals NHS FT
Director of R&D, ePAQ Systems Ltd
An STH, NHS spin-out technology company
141. Bristol female urinary
tract symptoms - Q
Birmingham
bowel & urinary
tract - Q
Sheffield prolapse
symptoms - Q
Female sexual
function index
ICS
Male
Pelvic Floor
Assessment (PAQ)
Questionnaires
Developing a web-based ‘Virtual Clinic’ in Urogynaecology
142. Radley S et al. Development & validation of a questionnaire for the
assessment of bowel symptoms in women. BJOG 2002
Radley SC et al. Computer interviewing in urogynaecology. BJOG 2006
143. Why an electronic
personal assessment
questionnaire (ePAQ)?
Burden
Value (interactive, simple & easy, help pages)
144. ePAQ – Pelvic Floor
A questionnaire for clinical use
154. Benefits of questionnaires in practice
• Embedded outcome measures (PROMs & PREMs) 1
• Avoiding clinician bias 2
• Engagement, enablement, empowerment 3
• Disclosure, discussion & shared decision making 4
1. Black et al Relationship between patient reported experience (PREMs) and
patient reported outcomes (PROMs) in elective surgery. BMJ 2013
2. Black et al. Impact of surgery for stress incontinence on morbidity: cohort study.
BMJ 1997
3. Dua et al: Understanding women’s experiences of electronic interviewing during
the clinical episode in urogynaecology: A qualitative study. IUGA Journal 2013
4. Schussler-Fiorenza et al. Using an electronic pelvic floor questionnaire to increase
discussion rates of urinary incontinence in primary care: an RCT. JWH 2015
155. Questionnaires to improve discussion & disclosure
Prevalence of coital incontinence in urogynaecology clinics
Author(s) Number Outcome measure Prevalence
Moran et al, 1999 2153 Interview 10.6%
Serati et al, 2008 132 Interview 11.6%
Madhu et al, 2015 11689 Interview 11.8%
Monsterrat et al, 2008 633 Questionnaire 36.2%
Bekker et al, 2009 136 Questionnaire 56%
El Azab, 2011 90 Questionnaire 66%
Jha et al, 2012 480 Questionnaire (ePAQ) 60%
Gray et al, 2016 2312 Questionnaire (ePAQ) 47%
156. The Virtual
Clinic
Name Tel Time
Anna Smith AS1234 078212344 14:00
Beryl Jones BJ8765 0114 3098909 14:10
Connie Lewis CL2345 0114 3897890 14:20
Diane Cole DC4567 07989997654 14:30
Edna Rose ER3847 07635668234 14:49
Fiona Groves FG2783 0114 3897890 14:50
Greta Holmes GH1783 0114 3897890 15:00
Heidi Hill HY7896 0114 3897890 15:10
Ida France TA1256 0114 3897890 15:20
Joanne Davies JD3456 0114 3897890 15:30
Kay Somers KS2365 07885668234 15:40
Lisa Tandy LY5698 0757 3897890 16:00
Margaret Smith MS3452 0114 3897890 16:10
Nora Bates NB2344 0114 3897890 16:20
Orla Charles OC3567 07835668234 16:30
Penelope Roper PR5702 07835668234 16:40
Rose Doyle RD5098 07835668234 16:50
Selena Bird SB8090 07835668234 17:00
Tina Moores TM3409 07835668234 17:10
Ursula King PL0987 07835668234 17:20
Violet Bonnett VB0934 07735668239 17:30
158. Patient comments…
I preferred answering embarrassing questions via the questionnaire
Helped focus on urgent and relevant problem
Made me realise the extent of my problem
Helped talk at ease about my problems
It was really easy to use
Not having to worry about childcare
Not being examined
159. Evaluating the impact of a ‘virtual clinic’ on the quality and cost of patient care in
urogynaecology: An RCT
Jones GL, Radley SR, Jacques RM, Wood HJ, Brennan V, Dixon S.
195 Women: New patient referrals to urogynaecology clinic
Mean difference between groups (95% CI) for post consultation Patient Experience (PEQ) score
160. Resource
Cost per patient
(Intervention) (£)
N = 27
Cost per patient
(control) (£)
N = 30
Mean Difference
(£)
95% CI
Lower
95% CI
Upper
P-value
Cost of
Consultations
Consultation cost1 29.35 69.52 -40.17 - - -
Cost of software 2.40 2.40 0 - - -
Cost of computer N/A 0.25 -.25 - - -
Total consultation
costs per pt 31.75 72.17 £40 (56%) - - -
Direct costs 6/12
GP Visits 41.22 35.33 5.89 -25.29 37.06 .654
Practice nurse 0.94 2.13 -1.18 -3.77 1.41 .063
Appointments 251 188 62.67 -87.02 212.36 .405
Surgery 330 286 44.88 -353.35 442.97 .822
Other professionals
Physio 5 5 .05 -7.58 7.68 .989
Nurse 4.5 2 2.49 -5.48 10.45 .534
Consultant 8 14 -6.35 -23.22 10.51 .454
Total direct costs 641 532 108.37 -346.93 563.67 .635
Indirect costs 6/12
Personal
expenditure (£)
24 16 7.9 -6.04 21.84 .261
Loss of productivity 443 481 -37.81 -847.04 771.42 .926
Total indirect costs 467 497 -29.91 -839.47 779.66 .946
Total costs per pt 1,140 1102 38.04 -1119.34 1196.03 .948
RCT: New patient referrals in urogynaecology
161. New instruments
• Menstrual Connor / Gray
• Vulva Palmer / Tidy
• Knee Sutton
• Vascular Michaels / Jones
• Cardiac Briffa
• Penile Ca Braney
• GTD Tidy / Ireson
• Pre Op Andrzejowski / Goodhart
162. • To develop and validate a novel electronic
instrument for pre-operative assessment: ePAQ-PO.
• The study was approved by the South Yorkshire
Regional Ethics Committee (REC 09/H1308/127)
• £50K Grant from Sheffield Hospitals Charity
– Full time nurse for a year
169. Conclusion…
e-assessment will be routine in healthcare,
patients will be…
Well-prepared
Well-informed
Have optimal communication tools & access
Engaged and responsible for their healthcare
Making best, informed decisions for themselves
Right place, right time, right clinician
173. 3D PRINTING IN CARDIOLOGY –
AN AID TO PERSONALISED
STRUCTURAL INTERVENTION?
Rob Cooper
Consultant Cardiologist
Liverpool Heart and Chest Hospital
174. Patient education
Closing holes in the heart
Atrial septal defects
Innovation agency
Planning operations for patients with
hypertrophic cardiomyopathy
3D Cardiac printing at LHCH
177. Cardio - myo - pathy
Heart - muscle - problem
Hypertrophic – thickened / overdeveloped
“Is my heart enlarged?”
“What does hypertrophic mean?”
“You’re going to do what to my heart?!”
Patient education
185. Mike has helped to educate:
2 years worth of HCM patients at LHCH
Junior doctors
Ward nurses
Nurse specialists
GPs
Geneticists
Radiographers
Echocardiographers
Consultant cardiologists
Why stop there?
Education
186. Moving on to normal
Muscle print
Blood volume print
187. Born with abnormal plumbing or unhelpful
holes in the heart.
Operated on usually in neonatal period
Complex operations (variation on a theme)
Then years of use
End result is complex adult hearts!
Adult congenital heart disease
188. Transposition of the great arteries
RV
To lungs
RV
To bodyTo body
LV
To lungs
LV
Normal Abnormal
191. From education to treatment
Atrial septal defects (hole in the heart) predispose to heart
failure and stroke in adulthood
Often not diagnosed in childhood
In some cases closure of the hole is indicated
Can be done surgically
Can be ‘keyhole’
Closing holes in the heart
196. Funding from Innovation agency to print 15
successive ASD models
Site non-sterile devices in the defect the week
before
Hypothesis:
Siting a closure device in a 3D model before ASD
closure will reduce complications and wastage during
the procedure.
Understanding of the cardiac anatomy will improve
patients understanding of the procedure and ease
associated anxiety
ASD printing project
203. Attempts to build this in to NHS models and tariffs
Anecdotal evidence so far
Not a great currency to take to your finance officers
Approaching charities / local philanthropists to
support a formal project
?Reduce surgical operation times
?Reduce complications
Save money anywhere to squeeze a model in to the
operation cost!
Personalised model for myectomy
204. Patient education
ASD percutaneous (keyhole) closure guidance
Myectomy operation guidance
3D printing in Liverpool
208. April 2010 208September 2009 Commercial in ConfidenceOctober 2008 Commercial in Confidence 208
October 17 Commercial in confidence 208
October 2017 Northern Innovation, AHSN
209. The current practice falls short of an effective diagnostic standard
Current diagnostic techniques rely on visual indicators
Visual indicators are non-specific, highly variable, subjective and
labour-intensive
Some disease lacks the usual visual indicators making it very challenging
to identify
Therefore causing
Poor performance - high number of false positives
High false positive rate leads to overtreatment of patients and
increased cost of care
Unnecessary multiple diagnostic biopsies
1 in 4 treatment excisions are negative
Problems with Current Diagnostic Approach
October 2017 Northern Innovation, AHSN
210. How EIS Technology Works
Defined cell layers
Close packing of cells.
High electrical
impedance.
Disorganized with no
defined cell layers.
Increased extracellular
space.
Increased nuclear
cytoplasmic ratio.
Low electrical
impedance.
HealthyCervicalEpithelium
CIN3CervicalEpithelium
Electrical
Current
The electrical impedance of
cells is measured across a
range of frequencies. This
generates a tissue specific
spectrum. Therefore
changes in the spectrum
can be related to changes in
the underlying nature of the
tissue – depicted in the
spectra below.
Squamous
High grade (CIN2-3)
Low grade (CIN1)
Immature metaplasia
Columnar
October 2017 Northern Innovation, AHSN
211. Executive Summary
Zilico Ltd. manufactures next generation cancer diagnostic devices
Remove subjectivity and increase accuracy of results
Reduce costs and better target resources in screening programmes
Platform Technology based on Electrical Impedance Spectroscopy (EIS)
Differentiates normal, pre-cancer and cancer cells in real time
Patents granted in Europe, USA, Canada, Australia, Japan, India. Filed in Brazil
Lead product ZedScan for cervical cancer
Immediate addressable market opportunity of $500m ($700m including emerging markets)
Superior solution: Offers more accurate diagnosis in real-time, detecting additional disease
Helps clinicians to better manage patients
Already in routine use in the NHS
5 clinical trials completed & presented in peer-reviewed journals
Certification: CE marked (Sept 2013) cleared for EU launch. FDA expected in 2020
NICE (UK) has published a Medtech Innovation Briefing note on ZedScan
Significant growth opportunity as technology platform can be applied to a range of cancers, allowing for
product extensions
October 2017 Northern Innovation, AHSN
212. 1998
Applications for
cervical cancer:
Prof. J. Tidy & Prof.
B. Brown
2000
1st trial -
publication in
Lancet
2003
Founders receive
NEAT grant from
NHS
2006
UoS & NHS
form Zilico
2009/11
EU Multi-centre
trial completed
2005
3 further trials
2013
ZedScan
awarded CE
Mark
Evolution of ZedScan
£1m grant funding £6m equity investment
2014
ZedScan – 1st
commercial
order
October 2017 Northern Innovation, AHSN
Proof Of Concept
Technology
Optimisation /
HW
Development
Clinical
Evidence
213. STH - Medical Device Innovation
Support the academic research
Electronic and Mechanical design and development
Device production and labelling
Design and production to meet regulatory standards e.g. BS 60601
– Electrical safety +
Medical device risk management
Technical file production to support MHRA clinical trial applications
Clinical trial support – verification and validation activities in
respects of data accrued.
ZedScan QA as ongoing validation
216. Clinical pathway - ZedScan
Referral - 2-6 weeks
-ve+ve
+ve Results within 2 weeks
+ve -ve
Pap/LBC smear test
High
Grade
Low Grade
Borderline
Colposcopy
Dx Biopsy
< Low grade
precancer
High grade
precancer
Cancer
Another smear/colposcopy
within 6 months
LLETZ (excision)Treatment - Laser ablation,
Radiotherapy, Chemotherapy
ZedScan+
October 2017 Northern Innovation, AHSN
217. + ZedScan
The Future…mature healthcare markets
Referral - 2-6 weeks
-ve+ve
+ve
+ve -ve
HPV Test
HPV infection is
essential but
only 10% leads
to disease
Colposcopy
Dx Biopsy
< CIN 1CIN 2/3Cancer
Another smear/colposcopy
within 6 months
LLETZ (excision)Treatment - Laser ablation,
Radiotherapy, Chemotherapy
+ Cytology ?
“Conclusions The major concern with switching from cytology to more sensitive
HPV screening is management of the many HPV-positive women, including those
with still non-visible ≥CIN2 lesions. Our data support the need for a non-visual
diagnostic method to guide management and treatment of HPV-positive
women."
Schiffman et al 2011
“Conclusions: Human papillomavirus type 16 is related to more clear visual
acetowhite changes in the epithelium. Therefore, we should expect a
reduction of the performance of VIA for cervical cancer screening to identify
women with CIN2+, and reduction of the performance of colposcopy
to diagnose CIN2+, in vaccinated populations."
Jeronimo et al 2015
October 2017 Northern Innovation, AHSN
218. Real World Data – 1570 women
Detect more disease
An additional 13.25% of high-grade disease was identified.
50% increase in women with low grade abnormalities
Average biopsy rate was lower – 285 fewer biopsies
Colposcopy failed to identify 14.1% of all high-grade histology whereas ZedScan only failed to identify 3.8% of
all high-grade histology.
The ‘See and Treat’ rate has increased from 36-39% in previous years to 68% high-grade disease was
confirmed in 94.2% of the case exceeding the value of 90% PPV indicated by the national guidelines.
There has been a decline of >40% (302 appointments) in the number of follow up appointments since the
introduction of ZedScan.
October 2017 Northern Innovation, AHSN
220. Health Economics
1000
New patients pa
Colposcopy
HHH
HH H
£ £ £ £ £ £ £
£ £ £ £
Colposcopy &
ZedScan
£ £ £ £ £ £ £
£ £
Biopsies
Appointments
& follow ups
£210K net savings
1443 clinic appointments released
3 Years3 Years
HHH
H
6015 4572
3078
£0.85M
2008
£1.06M
-24%
-20%
-35%
October 2017 Northern Innovation, AHSN
221. Are you 1o HPV Ready?
England moving to 1o HPV in 2019 replacing smears
6 centre sentinel study
60% increase in referrals
HPV +ve Cytology –ve women
CSW meeting last month
70% increase in referrals
Need technology to manage this capacity time bomb!
October 2017 Northern Innovation, AHSN
223. Mobilise the NHS
Sarah Thew
Innovation Manager
Health Innovation Manchester
Chris Chapman
Salford Royal Foundation Trust
224. Click to edit Master title
Problems that Matter
Codesign Partnerships between the
NHS and Digital SMEs
Sarah Thew
Health Innovation Manchester
Chris Chapman
Salford Royal Foundation Trust
225. Click to edit Master title
Great design
depends upon a
deep understanding
of the problem
226. Click to edit Master title
A
Juicy Salif
Philippe Starck for Alessi
227. Click to edit Master title
A
UK Motorway Sign
Photo Credit: www.kitchen-kraft.co.uk
228. Click to edit Master title
How do we enable
great design in the
NHS?
230. Click to edit Master title
Mobilise the NHS
9Partnerships
Creative Partnerships between Clinicians and SMEs
3 Ongoing
CollaborationsPhysiotherapy
Teenage Diabetic
Support
Metabolic Disorders
Ongoing medical
education
Emergency Stoke Care
Anti-microbial
management
Diagnosis of autism
In-patient
communication support
Rheumatoid Arthritis
2015 Bolton FT
2016/16 Salford
Royal and the
NorthWest
Ambulance
Service
5
SMEs continue to
work with the NHS
More post-it notes
and cake that you
can imagine…!
231. Click to edit Master title
What next?
User Research to
Identify and Drive
Informatics Projects
Community building
232. Click to edit Master title
Thanks for Listening
Sarah.Thew@healthinnovationmanchester.org
@Sarri
Chris.Chapman@srft.nhs.uk
233. The Innovation Pathway in an Acute Trust
Charlotte Fox
Innovation Manager
City Hospitals Sunderland NHS Foundation Trust
234. The Innovation Pathway in an Acute Trust
Charlotte Fox, Innovation Manager
City Hospitals Sunderland NHS Foundation Trust
@charlottefox22@SunderlandRoyal
235. • CHSFT Innovation Journey
• Importance of structure
• Developing a pathway
• Networking to support the
pathway
• Case Studies
236. Our Innovation Journey
• Innovation at CHSFT was
launched in January 2015
• Using AHSN funding
appointed an Innovation
Manager and
Administrative Assistant
• As well as….
https://www.pinterest.com/explore/life-journey-quotes/
238. Director of Research &
Development
Research & Development
Business Manager
Research & Development
Manager
Senior Research Nurse
3x Research Nurses
Clinical Trials Officer
Research & Development
Officer
Data Manager
Research & Development
Admin Assistant
Research & Development at CHSFT pre
Innovation
239. Director of Research &
Innovation
Research & Innovation
Business Manager
Research Manager
Research & Admin
Assistant
Innovation Scouts
x4
Innovation
Admin Assistant
Deputy Director of
Innovation Device &
Digital
Deputy Director of
Innovation
Clinical Pathways & POCT
Deputy Director of
Research
Innovation Manager
Data Managers
x3
Research Nurses
(Generic)
x7
Research
Administration
Officer
Current Research &
Innovation
Structure at CHSFT
Innovation
Management
Trainee
243. Networking
• Find Opportunities
• Benefitted the organisational
reputation
• Built trusted relationships
• Plugs gaps in knowledge
“What you pay forward will
pay back in the future”
http://www.cyclonelife.net/2017/03/how-to-spend-your-spring-break-at-home/networking-meme/
248. Unmet need: Accidental line
fall out of Central Venous
Catheter
Occurs in ~20% of patients
Each line re-instatement costs
the NHS approximately
£3,000.00
https://www.cancer.gov/publications/dictionaries/cancer-terms?cdrid=45962
Connect
249.
250.
251. Solution: Adapting the Tookie
Paediatric Oncology Vest for
Renal patients to secure the
catheter
Tookie ethos is
#ALifeMoreNormal
Improving patient safety &
experience
252. • Medconnect North with City Hospitals Sunderland and Tookie
facilitated patient workshops to develop the vest
• The vest is now being manufactured
• It will be evaluated as part of a multicentre clinical trial
253. All About Me Boards
Debbie Hindmarsh
Ward Manager
Acute Stroke Unit
254. Communication problems are very common after stroke, around one
third of stroke survivors have problems with speaking, reading,
writing and understanding what other people say to them
When we communicate, our brain has to complete a series of tasks.
Different parts of the brain are responsible for each of these tasks. If
one of these parts is damaged by a stroke, it can cause problems
with communication
Unmet need: Communication
255. In response to a complaint from a different area in the Trust, a
patient who had previously had a stroke struggled to articulate his
nursing needs which resulted in distress for both the patient and his
relatives
As an organisation we listen to our patients and relatives and we
responded and acted upon comments from real time feedback about
them not being involved in their loved ones care and decision making
Using Lessons Learnt
256. Next steps
All about me...
Patient, family & friends: Please feel free to share information, pictures etc....
I prefer to
be called
You might be surprised
to know....
My favourite things:
activities, food, movies, games,
books, music, TV, etc,).....
Items that comfort me.....
Today's news...
Things I may need help with
(include fears)...
260. CHS Shoulder Bench
Developed by: Ala Mohammed, ED Consultant. City Hospitals Sunderland NHS
Foundation Trust
Multidisciplinary Training
Sessions
Online Training Video
Putting Research into
Practice
Shared learning and
innovation
Direct access from ED to new
Shoulder Dislocation Clinic
41% Less Procedural
Sedations Required
34% Reduction in Time to
Successful Treatment
29% Reduction in Time to
Discharge
6 week Reduction in Time to
specialist follow up
261.
262. Next Steps & Poster Competition Winners
Juliette Kumar
Associate Director of Education and Improvement
The Innovation Agency