The document discusses the Innovation Exchange and SBRI Healthcare programs which aim to accelerate the development and adoption of innovative healthcare solutions in England. It provides background on Karen Livingstone, the director of the programs. It then outlines key forces shaping global healthcare and describes the 15 Academic Health Science Networks that work locally and nationally to drive innovation adoption across England. The rest of the document details how the Innovation Exchange identifies healthcare needs and supports companies through funding competitions, needs assessments, and providing support to help ready solutions for adoption across the NHS. It provides examples of companies it has supported in areas like patient engagement, chronic condition management, and early disease detection.
Translate: Medical Technologies in the Leeds City Region is a new partnership of universities in the Leeds City Region with world-class expertise in the development of new medical technologies. Translate are working in partnership with DHEZ and the University of Bradford.
A very important result from the EUPATI project was the development, broad consultation and final release of guidances on the best approach to interaction of patients with pharmaceutical industry-led medicines R&D, regulatory authorities, ethics committees and HTA agencies. This webinar focuses on the Patient Involvement in Industry-led R&D guidance document
Presentation by Andy Cairns, Programme Manager, Innovation Agency: Welcome and introduction at the Funding - Liverpool City Region SME workshop on Thursday 7 February 2019 at The Accelerator, Liverpool
Translate: Medical Technologies in the Leeds City Region is a new partnership of universities in the Leeds City Region with world-class expertise in the development of new medical technologies. Translate are working in partnership with DHEZ and the University of Bradford.
A very important result from the EUPATI project was the development, broad consultation and final release of guidances on the best approach to interaction of patients with pharmaceutical industry-led medicines R&D, regulatory authorities, ethics committees and HTA agencies. This webinar focuses on the Patient Involvement in Industry-led R&D guidance document
Presentation by Andy Cairns, Programme Manager, Innovation Agency: Welcome and introduction at the Funding - Liverpool City Region SME workshop on Thursday 7 February 2019 at The Accelerator, Liverpool
At Dakota's technology showcase Trusts also heard from Peter Coates, Open Source Programme Head for NHS England. Here is are the materials he shared with us showing the benefits for the NHS set within the wider public sector technology objectives.
Presentation of CRAASH Barcelona, the new project of Biocat (Moebio Barcelona). The initiative is a 12-week program that helps European research teams launch successful device, diagnostic and e-/digital health innovations to improve health and patient care.
Mogens Sehested's, Per Grønbech's, Christian Christensen's, Jesper Allerup's,...Healthcare DENMARK
All presentations from the panel discussion with Mogens Sehested (Chief Financiel Officer, Central Denmark Region), Per Grønbech (Chief Financiel Officer, Region of Southern Denmark), Christian Christensen (Chief Procurement Officer, Zealand Region), Jesper Allerup (Head of Unit, Research and Innovation, Capital Region of Denmark), and Kjeld Lisby (Chief Innovation Officer, North Denmark Region).
Helle Gaub's presentation from Hospital + Innovation 2015Healthcare DENMARK
Helle Gaub's (Project Director, University Hospital Koege, Region Zealand) presentation from the Hospital + Innovation Congress 2015 in Odense, Denmark.
Niki Nicolas Grigoriou's presentation from Hospital + Innovation 2015Healthcare DENMARK
Niki Nicolas Grigoriou's (CEO and Software Architect, Intelligent Systems A/S) presentation from the Hospital + Innovation Congress 2015 in Odense, Denmark.
"Improving Decision Making in Health & Social Care Through Quality Information & Technology": Dr. Mark Davies (Director of Clinical and Public Assurance) of the Health and Social Care Information Centre (HSCIC) discusses this at the Healthcare Efficiency Through Technology Expo 2013.
First eStandards conference Healthcare Executives Panel Introductionchronaki
This is the introduction to a panel in the first eStandards conference aiming to bring together with Hospital CIOs, actors in the healthcare system: representative of payers, healthprofessionals to get a sense of the issues with interoperability in largescale eHealth deployment.
ONC Market R&D Pilot challenge Webinar finalhealth2dev
The Market R&D Pilot Challenge, brought to you by the Office of the National Coordinator for Health Information Technology (ONC), will help bridge technological gaps by bringing together health care organizations and innovative companies through $300,000 in pilot funding awards and facilitated matchmaking. This webinar provides more detail on the challenge and answers some common questions
New Funding & Development Opportunities for InnovatorsIsabelle Sparrow
On November 8th GM AHSN invited innovators from the region to an event at the Nowgen Centre in Manchester. The event provided information about some of the current funding and support opportunities available to healthcare innovators, including programmes from GM AHSN's Innovation Nexus, SBRI Healthcare and the Business Growth Hub.
Executive Healthcare Seminar - Belgium - Saudi Arabia - Belgian Embassy RiyadhJan Demey
Belgian and Saudi Healthcare executives met in the Belgian Embassy to discuss several topics in the evolving healthcare market and the Vision 2030 of the Kingdom of Saudi Arabia. The ambition to work together to make healthcare better is our joined ambition. This presentation brings the supporting ideas as discussed during the seminar.
At Dakota's technology showcase Trusts also heard from Peter Coates, Open Source Programme Head for NHS England. Here is are the materials he shared with us showing the benefits for the NHS set within the wider public sector technology objectives.
Presentation of CRAASH Barcelona, the new project of Biocat (Moebio Barcelona). The initiative is a 12-week program that helps European research teams launch successful device, diagnostic and e-/digital health innovations to improve health and patient care.
Mogens Sehested's, Per Grønbech's, Christian Christensen's, Jesper Allerup's,...Healthcare DENMARK
All presentations from the panel discussion with Mogens Sehested (Chief Financiel Officer, Central Denmark Region), Per Grønbech (Chief Financiel Officer, Region of Southern Denmark), Christian Christensen (Chief Procurement Officer, Zealand Region), Jesper Allerup (Head of Unit, Research and Innovation, Capital Region of Denmark), and Kjeld Lisby (Chief Innovation Officer, North Denmark Region).
Helle Gaub's presentation from Hospital + Innovation 2015Healthcare DENMARK
Helle Gaub's (Project Director, University Hospital Koege, Region Zealand) presentation from the Hospital + Innovation Congress 2015 in Odense, Denmark.
Niki Nicolas Grigoriou's presentation from Hospital + Innovation 2015Healthcare DENMARK
Niki Nicolas Grigoriou's (CEO and Software Architect, Intelligent Systems A/S) presentation from the Hospital + Innovation Congress 2015 in Odense, Denmark.
"Improving Decision Making in Health & Social Care Through Quality Information & Technology": Dr. Mark Davies (Director of Clinical and Public Assurance) of the Health and Social Care Information Centre (HSCIC) discusses this at the Healthcare Efficiency Through Technology Expo 2013.
First eStandards conference Healthcare Executives Panel Introductionchronaki
This is the introduction to a panel in the first eStandards conference aiming to bring together with Hospital CIOs, actors in the healthcare system: representative of payers, healthprofessionals to get a sense of the issues with interoperability in largescale eHealth deployment.
ONC Market R&D Pilot challenge Webinar finalhealth2dev
The Market R&D Pilot Challenge, brought to you by the Office of the National Coordinator for Health Information Technology (ONC), will help bridge technological gaps by bringing together health care organizations and innovative companies through $300,000 in pilot funding awards and facilitated matchmaking. This webinar provides more detail on the challenge and answers some common questions
New Funding & Development Opportunities for InnovatorsIsabelle Sparrow
On November 8th GM AHSN invited innovators from the region to an event at the Nowgen Centre in Manchester. The event provided information about some of the current funding and support opportunities available to healthcare innovators, including programmes from GM AHSN's Innovation Nexus, SBRI Healthcare and the Business Growth Hub.
Executive Healthcare Seminar - Belgium - Saudi Arabia - Belgian Embassy RiyadhJan Demey
Belgian and Saudi Healthcare executives met in the Belgian Embassy to discuss several topics in the evolving healthcare market and the Vision 2030 of the Kingdom of Saudi Arabia. The ambition to work together to make healthcare better is our joined ambition. This presentation brings the supporting ideas as discussed during the seminar.
Putting innovation into practice (NHS vs Widnes Vikings)Richard Harding
Where is the Front Door to the NHS?
How do we procure innovation and innovate procurement in Health?
What does health want?
How does an SME leverage Local Infrastructure
Academic Health Science Networks supporting strategic commissioningInnovation Agency
Dr Liz Mear, Chief Executive of the Innovation Agency, presented at NHS Confed 17 on Academic Health Science Networks (AHSNs) supporting strategic commissioning and bringing innovators, commissioners, clinicians and patients to together to develop closer collaboration and a demonstrably clearer understanding of NHS needs and opportunities.
eHealth Summit: "Case Study: The applied research for connected health (ARCH)...3GDR
Slides from National eHealth Summit, 30 Sept 2015 at Carton House, Kildare: Maria Quinlan, Research Lead Change Work-Package, ARCH.
#eHealthSummit15
http://www.ehealthsummit.ie
http://mhealthinsight.com/2015/09/25/mhealth-insights-from-the-ehealth-summit/
Dr Liz Mear, Chief Executive of the Innovation Agency presented at NHS Confed 17 about the NHS’ role in growing local economies and how Academic Health and Science Networks (AHSNs) can generate economic growth in life sciences through their role as catalysts, connectors and collaborators by spreading innovation, advancing health technology and improving healthcare
Increasing the success rate of developing startup-corporate partnerships by a structured program to build and validate a joint value story
by Kors van Wyngaarden, Medical Officer @Philips HealthWorks
Based on extensive experience in engaging with startups in 12 weeks programs Philips HealthWorks is continuously tweaking their approach to increase the value of sustainable partnerships between Philips and Healthcare startups. Kors will share how HealthWorks uses a structured approach, stakeholder and ecosystem engagements to help startups increase their own value and, in parallel, to build and validate the partnership value story.
Transforming Clinical Practice InitiativeCitiusTech
The Transforming Clinical Practice Initiative (TCPI) is designed to help small practices and clinicians achieve large-scale health transformation. The initiative is designed to support more than 140,000 clinician practices over four years duration in sharing, adapting and further developing their comprehensive quality improvement strategies. The TCPI is one part of a unique strategy advanced by the Affordable Care Act to strengthen the quality of patient care and manage health care expenditures, ultimately saving the taxpayer from substantial costs. This document describes the initiative in detail with the type of participants, eligibility and reporting requirements of the participants. Understanding the implementation of this initiative not only helps clinicians, but opens up a huge market for Healthcare IT companies offering the products and services like EHR implementation, Integration, EHR/ Data Migration, Implementation of HIE etc.
The external healthcare environment is changing rapidly and providers are under increasing pressure to innovate with increasing speed and efficiency.
Be it experimenting with new care delivery models to improve care coordination, redesigning workflows to enhance efficiency, or developing new products that improve clinical outcomes, hospitals and their service lines are looking for effective ways to harness the creative power of physicians and employees to solve problems that matter. However, few organizations innovate in an orderly, reliable way.
Great ideas remain captive in the heads of physicians and employees and one-off attempts to spur innovation through “hack-a-thons” and “pitch days” prove disappointing. As an academic medical center and a world leader in orthopedics, Hospital for Special Surgery has a long history of results-oriented innovation.
In this webinar, we will share:
– HSS’ systematic approach for driving innovation
– strategies for generating new insights and developing novel solutions
– processes for piloting and testing new ideas
– guiding principles for creating a culture of innovation
– advice on how to build your very own innovation infrastructure
About the Speaker:
Mark Angelo is Vice President, Innovation & Business Development for Hospital for Special Surgery. Mark joined HSS in 2009 and has held various senior management positions at the Hospital across operations, strategy and business development. As Vice President, Innovation & Business Development, Mark is responsible for advancing hospital strategic priorities related to quality and efficiency, innovation, growth and diversification. One of his key responsibilities includes leading the Operational Excellence program, a hospital-wide initiative that leverages industrial engineering principles to maximize quality and efficiency. Mark also leads the HSS Innovation Center whose mission is to support the development and commercialization of early-stage technologies and solutions.
Prior to joining HSS, Mark worked as a management consultant for Monitor Group where he specialized in operations strategy and organizational design. Mark holds a Bachelor of Applied Science in Biomedical Engineering from the University of Toronto and a Master of Business Administration from Harvard Business School.
Rachael Colley - Transformation of Procurement in the Changing NHS Landscape.Innovation Agency
Presentation by Rachael Colley, Head of Procurement Solutions and Innovation, NHS Shared Business Services on The Transformation of Procurement in the Changing NHS Landscape on Thursday 20 September at Northwich Memorial Court.
The MaRS EXCITE (Excellence in Clinical Innovation and Technology Evaluation) program helps innovators collaborate with the health system to accelerate the pace of adoption of innovative health technologies in Ontario and global markets.
At the end of the program, innovators will have feedback and data on the effectiveness, competitiveness, and economic value of their medical devices or health technology. With this data, innovators are better equipped to approach payers in multiple markets for reimbursement.
Prioritized by senior executives from the health system, only technologies that have true breakthrough potential are allowed into the program.
For more information visit www.marsdd.com.
Similar to Karen Livingstone - ECO 17: Transforming care through digital health (20)
Presentations by Tawfiq Choudhury and Rocco Hadland from the second webinar of the Mastering Cholesterol webinar series on Thursday 11 May 2023, focusing on Statins.
Targeting lipids: a primary and secondary care perspectiveInnovation Agency
Presentations by Dr Sue Kemsley and Dr Gavin Galasko from the first webinar of the Mastering Cholesterol webinar series on Thursday 26 January 2023, focusing on lipid management from a primary and secondary care perspective.
Supporting the optimal detection and management of BP in Primary CareInnovation Agency
Presentation by Jane Briers, Programme Manager - Innovation Agency at the Supporting recovery in Primary Care using Proactive Frameworks for Long Term Conditions event on Thursday 15 September 2022.
Presentation by Dr Lauren Moorcroft, GP Partner - Brookvale Practice at the Supporting recovery in Primary Care using Proactive Frameworks for Long Term Conditions event on Thursday 15 September 2022.
Introduction to Supporting recovery in Primary Care using Proactive Framework...Innovation Agency
Presentation by Julia Reynolds, Associate Director for Transformation - Innovation Agency at the Supporting recovery in Primary Care using Proactive Frameworks for Long Term Conditions event on Thursday 15 September 2022.
Presentation by Paul Brain, Project Manager at the Excel in Health series - Introduction to data webinar on Monday 6 June 2022.
In this session we discussed how SMEs can use data to grow their business and access new opportunities in the market.
Presentations by Mike Kenny, Acting Co-Director of Enterprise and Growth, Innovation Agency and Dr Neil Paul, a GP and Board Member with Cheshire East ICP at the Excel in Health: Understanding the NHS Landscape webinar on Wednesday 11 May 2022.
LCR and Cheshire and Merseyside Health MATTERS networking eventInnovation Agency
Master slide deck from the LCR and Cheshire and Merseyside Health MATTERS networking event on Wednesday 24 November 2021 at Sci-Tech Daresbury Laboratory.
Master slide deck from the Excel in Health webinar series: The NHS landscape presentation.
This webinar identifies the structure of the NHS and its national priorities.
The session will cover the following topics:
Understand the structure of the NHS
Understand the national priorities of the NHS
Recognise the barriers to sale
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Karen Livingstone - ECO 17: Transforming care through digital health
1. The Innovation Exchange and SBRI Healthcare
Transforming Health and Social Care Services
4 December 2018
Eco 18
2. 2
• National Director NHS – leading £81m innovation programme
• Fellow of the Judge Business School, Cambridge
• Graduate of the Global Health Leadership, Yale University
• Formerly board member of 5 public and private boards
• Formerly Special advisor to Secretary of State for Health
• Politics graduate with 20+ years of national political
3. Forces shaping global healthcare
• Population pyramids are inverting
• Chronic disease will dwarf other needs
• Patient expectations are rising
• Emerging markets will be a large driver of growth across all
markets
• Financial pressures will require focus on productivity
• Health systems shifting to integrated care and outcomes
based payments
• Explosion of patient level healthcare data
• Innovation is rapidly evolving the life sciences towards
convergence
4. 15 Academic Health Science Networks (AHSNs)
across England.
• 15 Academic Health Science Networks, complete
coverage of England
• Five-year licence to drive innovation, adoption
and spread
• Working nationally to deliver major programmes
such as the Accelerated Access Review and the
Innovation Exchange
• Working locally to support transformation and
improvement, linking with STPs and other key
partners
www.ahsnnetwork.com
5. Evidence assessment frameworks & evaluation of evidence
Innovation support landscape
Proof of
concept Development Testing
Clinical
Trials Adoption 1
Regional
adoption
Wide spread
adoption
SBRI Healthcare
NIA Accelerator
National Institute for
Health Research
Innovation Technology
Payments
Clincal entrepeneurs
Digital accelerator
Med Tech
Accelerator
Venture funding
Innovate UK
Angel funding
Accelerated Access
Collaborative
The INNOVATION Exchange
6. Ideas into Practice
Accelerate solutions
• Define problems: 3-5 year
• Create solutions through
competitive process
• Invest in their co-development
• Develop solutions that bring
patient & economic success
Accelerate adoption
• Define problems: 1-3 year
• Support NHS to adopt ready to
use solutions
• Support innovators to navigate
& connect
• Broker solutions that bring
patient and economic value
The INNOVATION Exchange
7. Contract
Due diligence &
contracting. Fix and
agree milestones.
Interview Panel: 360 assessment
– investor style consideration of
tech, business and clinical
considerations
Clinical assessment: match to identified
need. Provenance of science/technology
approach. Team – engagement of clinical/
user voice
Tech assessment: competitive environment/ IP /
technology development / assessment of project plan &
deliverables
Workshop & briefings: specialist help from problem holders –
guidance to companies on NHS market access & reality of workplace
environment
Needs identification: policy context/service assessments / detailed workplace
considerations
AHSN support
• Access to key clinicians
• Access to patient groups
• Trial/pilot sites
• Roll out from one to many
SBRI team support
• Health Economic analysis &
market access understanding
• Support through ethics
approval & establishing clinical
trials
• Connection to UKTI, HMRA &
others
Approx
300/comp
Approx 130
apply
Approx 60
Approx 15
(12%)
SBRI funds
Phase 1 award: £100k – 6 months
Phase 2 award: up to £1m
9. Creation – case studies
Dovetail:
Working with blockchain
solutions to give patients full
control of their healthcare
records and deliver collaborative
exchange of data between
health services.
Increasing accountability and
mitigating risk and maximising
health outcomes for patients.
Brain Miner is developing
Diagnosis in Dementia (DIADEM),
an automated, extensible, and
personalised healthcare platform for
assisting the clinical diagnosis of
dementia. DIADEM using currently
available imaging data by delivering
a software infrastructure that can
automatically and intelligently
analyse MR imaging data and feed
the results to the end-user clinicians
in a visually intuitive fashion.
Owlstone Medical -
Ambition to save 100,000 lives &
$1.5bn in healthcare costs
Early detection of lung cancer is
first target.
Colorectal Cancer next target:.
Medium term: stratification of
asthma treatment.
Analysis of non-invasive
biomarkers in breath.
Company supported to connect
Clinical leads, patient voice &
backed for investors
10. From bench to bedside – case studies
uMotif/ADI/MyMHealth
iPLATO digital hub with a
population-wide, multi-channel
patient engagement platform
connected to consenting GP
practices. It allows regional
teams working in partnership
with GP surgeries to run
powerful, data driven, patient
engagement campaigns
across SMS.
365 response has a number of
cloud-based technology
solutions for transportation
companies, councils, facilities
management organisations and
community and social care
transport providers.
They offer a complete transport
and flow system, with auditable
compliance.
A range of companies with
patient engagement and
condition management tools.
ADI – pain management
uMotif – participation and
informed patients
My mHealth – chronic condition
management tools.
11. Ideas into Practice
Accelerate solutions
• Define problems: 3-5 year
• Create solutions through
competitive process
• Invest in their co-development
• Develop solutions that bring
patient & economic success
Accelerate adoption
• Define problems: 1-3 year
• Support NHS to adopt ready to
use solutions
• Support innovators to navigate
& connect
• Broker solutions that bring
patient and economic value
The INNOVATION Exchange
12. How the innovation exchange works
1. Innovator support and sign posting
A range of support for Innovators – SMEs, clinical entrepreneurs, digital, medtech, biotech.
Support to engage with the Innovation Exchange and across the NHS
6. Adoption and spread
Some products will be adopted in regionally supported
activity others in nationally led programmes
2. Needs Articulation
Patients, clinical, managerial voices drawn in to help define needs.
Needs will reflect the market opportunity as well as the efficiency expectations of the NHS.
3. Real world validation
Pathway testing of clinically validated innovations – to enable
workflow, training and system planning to be tested.
Economic and impact reviews will be shared across the AHSNs
1billion more people on the planet – 90% of whom will be in merging markets
Half a billion more people older than 50 and >320m people older than 80 by 2030
Chronic Diseases (those that are persistent/long lasting eg arthritis, asthma, COPD diabetes) will account for over 80% of (DALYs – disability adjusted life years)
By 2025 the global economy will almost double compared to today – led by Asia.
By 2023 emerging market pharma sales will account for 45% of the global total (up from 35% now)
NHS productivity shortfall likely to be £28bn by 2023
The Innovation Exchange is an AHSN coordinated approach to identify, select and support the adoption of innovations that improve our economy and patients lives.
The Innovation Exchange has four structured elements: needs articulation; innovator support & signposting; real world validation and spread adoption of supported innovations.
The Innovation Exchange will identify innovations for the Accelerated Access Collaborative and for local adoption.