Neonatal necrotizing enterocolitis
NEC is the most common life-threatening emergency of the gastrointestinal tract in the newborn period. The disease is characterized by various degrees of mucosal or transmural necrosis of the intestine. The cause of NEC remains unclear but is most likely multifactorial. The incidence of NEC is 1-5% of infants in neonatal intensive care units (NICUs). Both incidence and case fatality rates increase with decreasing birthweight and gestational age. Because very small, ill preterm infants are particularly susceptible to NEC, a rising incidence may reflect improved survival of this high-risk group of patients.
Clinical Manifestations
Infants with NEC have a variety of signs and symptoms and may have an insidious or sudden catastrophic onset (Table 96-1). The onset of NEC is usually in the 2nd or 3rd week of life but can be as late as 3 mo in VLBW infants. Age of onset is inversely related to gestational age. The 1st signs of impending disease may be nonspecific, including lethargy and temperature instability, or related to gastrointestinal pathology, such as abdominal distention and gastric retention. Obvious bloody stools are seen in 25% of patients. Because of nonspecific signs, sepsis may be suspected before NEC. The spectrum of illness is broad, ranging from mild disease with only guaiac-positive stools to severe illness with bowel perforation, peritonitis, systemic inflammatory response syndrome, shock, and death. Progression may be rapid, but it is unusual for the disease to progress from mild to severe after 72 hr.
Diagnosis
A very high index of suspicion in treating preterm at-risk infants is crucial. Plain abdominal radiographs are essential to make a diagnosis of NEC. The finding of pneumatosis intestinalis (air in the bowel wall) confirms the clinical suspicion of NEC and is diagnostic; 50-75% of patients have pneumatosis when treatment is started (Fig. 96-4). Portal venous gas is a sign of severe disease, and pneumoperitoneum indicates a perforation (Figs. 96-4 and 96-5). Hepatic ultrasonography may detect portal venous gas despite normal abdominal roentgenograms .
Neonatal necrotizing enterocolitis
NEC is the most common life-threatening emergency of the gastrointestinal tract in the newborn period. The disease is characterized by various degrees of mucosal or transmural necrosis of the intestine. The cause of NEC remains unclear but is most likely multifactorial. The incidence of NEC is 1-5% of infants in neonatal intensive care units (NICUs). Both incidence and case fatality rates increase with decreasing birthweight and gestational age. Because very small, ill preterm infants are particularly susceptible to NEC, a rising incidence may reflect improved survival of this high-risk group of patients.
Clinical Manifestations
Infants with NEC have a variety of signs and symptoms and may have an insidious or sudden catastrophic onset (Table 96-1). The onset of NEC is usually in the 2nd or 3rd week of life but can be as late as 3 mo in VLBW infants. Age of onset is inversely related to gestational age. The 1st signs of impending disease may be nonspecific, including lethargy and temperature instability, or related to gastrointestinal pathology, such as abdominal distention and gastric retention. Obvious bloody stools are seen in 25% of patients. Because of nonspecific signs, sepsis may be suspected before NEC. The spectrum of illness is broad, ranging from mild disease with only guaiac-positive stools to severe illness with bowel perforation, peritonitis, systemic inflammatory response syndrome, shock, and death. Progression may be rapid, but it is unusual for the disease to progress from mild to severe after 72 hr.
Diagnosis
A very high index of suspicion in treating preterm at-risk infants is crucial. Plain abdominal radiographs are essential to make a diagnosis of NEC. The finding of pneumatosis intestinalis (air in the bowel wall) confirms the clinical suspicion of NEC and is diagnostic; 50-75% of patients have pneumatosis when treatment is started (Fig. 96-4). Portal venous gas is a sign of severe disease, and pneumoperitoneum indicates a perforation (Figs. 96-4 and 96-5). Hepatic ultrasonography may detect portal venous gas despite normal abdominal roentgenograms .
Definition of neonatal sepsis,type of neonatal sepsis ,early onset neonatal sepsis,late onset neonatal sepsis,Pathophysiology of neonatal sepsis,,sign and symptoms of neonatal sepsis, diagnosis of neonatal sepsis,management of neonatal sepsis, antibiotic used for neonatal sepsis,prevention of neonatal sepsis, prognosis of neonatal sepsis ,and A summary
Chronic Liver Disease in pediatric: a case presentation and discussionDr Abdalla M. Gamal
A presentation from a tutorial about an interesting case that came to the Pediatric Department of Sebha Medical Center and was imaged by the Radiology Department.
The tutorial was a joint effort between Dr Zeinab Salem Ali (from Pediatric Department) and me (from Radiology Department). In her slides, Dr Zeinab presented the case history, examination, investigations, differential diagnosis and discussed the clinical presentation, investigations and management for chronic liver diseases in pediatric patients.In my slides, I discussed the definition, etiology, natural history of this condition and explained the role of imaging in its diagnosis.
These are my slides after some modifications. I added an aknowlegement page to illustrate Dr Zeinab effort and to thank Dr Khaled Aljasem from Pediatric Department for his effort in revising the original presentations and the constructive feedback he provided which improved the quality of the presented material. Then I added a summary for the parts Dr Zeinab has presented to make this powerpoint presentation complete.
This presentation was presented by Dr Zeinab Salem (from Pediatric Department) and me in a joint tutorial between Pediatric Department and Radiology Department of Sebha Medical Center.
NEONATAL BILIOUS VOMITING- PART 1 & 2
Dear Viewers,
Greetings from “Surgical Educator”
Today I have uploaded two videos on “Neonatal bilious Vomiting- Part 1 & 2. In this episode, I talked about various congenital causes for bowel obstruction in neonatal babies that also cause bilious vomiting. Since there are many causes, I have created two videos to cover everything. In Part1, I talked about duodenal atresia, annular pancreas, malrotation, jejunal & ileal atresia and necrotising enterocolitis. In Part2, I talked about Hirschsprung’s disease, meconium ileus, meconium plug, small left colon syndrome and meconium peritonitis. I request you to watch both videos together and I hope you will enjoy them. You can watch all my surgical teaching video casts in the following links:
Surgicaleducator.blogspot.com
Youtube.com/c/surgicaleducator
Thank you for your support.
I have included in this PPT slides the various causes for acute abdomen- Ac Appendicitis, Ac Cholecystitis, Ac Pancreatitis, Peptic Ulcer Disease, Small Bowel Obstruction, Mesenteric Ischemia and sigmoid Colon. you can read and learn all these acute abdominal problems in this one PDF file.
Definition of neonatal sepsis,type of neonatal sepsis ,early onset neonatal sepsis,late onset neonatal sepsis,Pathophysiology of neonatal sepsis,,sign and symptoms of neonatal sepsis, diagnosis of neonatal sepsis,management of neonatal sepsis, antibiotic used for neonatal sepsis,prevention of neonatal sepsis, prognosis of neonatal sepsis ,and A summary
Chronic Liver Disease in pediatric: a case presentation and discussionDr Abdalla M. Gamal
A presentation from a tutorial about an interesting case that came to the Pediatric Department of Sebha Medical Center and was imaged by the Radiology Department.
The tutorial was a joint effort between Dr Zeinab Salem Ali (from Pediatric Department) and me (from Radiology Department). In her slides, Dr Zeinab presented the case history, examination, investigations, differential diagnosis and discussed the clinical presentation, investigations and management for chronic liver diseases in pediatric patients.In my slides, I discussed the definition, etiology, natural history of this condition and explained the role of imaging in its diagnosis.
These are my slides after some modifications. I added an aknowlegement page to illustrate Dr Zeinab effort and to thank Dr Khaled Aljasem from Pediatric Department for his effort in revising the original presentations and the constructive feedback he provided which improved the quality of the presented material. Then I added a summary for the parts Dr Zeinab has presented to make this powerpoint presentation complete.
This presentation was presented by Dr Zeinab Salem (from Pediatric Department) and me in a joint tutorial between Pediatric Department and Radiology Department of Sebha Medical Center.
NEONATAL BILIOUS VOMITING- PART 1 & 2
Dear Viewers,
Greetings from “Surgical Educator”
Today I have uploaded two videos on “Neonatal bilious Vomiting- Part 1 & 2. In this episode, I talked about various congenital causes for bowel obstruction in neonatal babies that also cause bilious vomiting. Since there are many causes, I have created two videos to cover everything. In Part1, I talked about duodenal atresia, annular pancreas, malrotation, jejunal & ileal atresia and necrotising enterocolitis. In Part2, I talked about Hirschsprung’s disease, meconium ileus, meconium plug, small left colon syndrome and meconium peritonitis. I request you to watch both videos together and I hope you will enjoy them. You can watch all my surgical teaching video casts in the following links:
Surgicaleducator.blogspot.com
Youtube.com/c/surgicaleducator
Thank you for your support.
I have included in this PPT slides the various causes for acute abdomen- Ac Appendicitis, Ac Cholecystitis, Ac Pancreatitis, Peptic Ulcer Disease, Small Bowel Obstruction, Mesenteric Ischemia and sigmoid Colon. you can read and learn all these acute abdominal problems in this one PDF file.
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Subsequently, in February, the committee successfully submitted its recommendations regarding amendments to the criminal law. These recommendations are intended to serve as a foundation for enhancing the current legal framework, promoting safety and security, and upholding the constitutional principles of justice, dignity, and the inherent worth of every individual.
NATURE, ORIGIN AND DEVELOPMENT OF INTERNATIONAL LAW.pptxanvithaav
These slides helps the student of international law to understand what is the nature of international law? and how international law was originated and developed?.
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ALL EYES ON RAFAH BUT WHY Explain more.pdf46adnanshahzad
All eyes on Rafah: But why?. The Rafah border crossing, a crucial point between Egypt and the Gaza Strip, often finds itself at the center of global attention. As we explore the significance of Rafah, we’ll uncover why all eyes are on Rafah and the complexities surrounding this pivotal region.
INTRODUCTION
What makes Rafah so significant that it captures global attention? The phrase ‘All eyes are on Rafah’ resonates not just with those in the region but with people worldwide who recognize its strategic, humanitarian, and political importance. In this guide, we will delve into the factors that make Rafah a focal point for international interest, examining its historical context, humanitarian challenges, and political dimensions.
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Car Accident Injury Do I Have a Case....Knowyourright
Every year, thousands of Minnesotans are injured in car accidents. These injuries can be severe – even life-changing. Under Minnesota law, you can pursue compensation through a personal injury lawsuit.
2. What is
Necrotizing
Enterocolitis?
Necrotizing Enterocolitis (NEC) occurs in
premature infants and involves damage
to the intestine. It can range from a
small mucosal lesion to full thickness
necrosis (death) of a portion of the
bowel.
GENERAL MEETING | 2020
3. Symptoms of
NEC
Feeding intolerance
Abdominal distention
Temperature instability
Lethargy
Vomiting
Bloody stools
If not promptly diagnosed and treated,
NEC can lead to bowel perforation,
peritonitis, sepsis and death.
Initial symptoms of NEC include:
4. Diagnosing NEC
NEC is usually suspected clinically, but is
confirmed with x-rays or other radiologic
studies. Diagnostic studies help identify
the severity, or Bell’s stage, of the disease.
5. Bell’s Stage 1:
Suspected Disease
Mild systemic disease with apnea
Bradycardia and temperature instability
Mild abdominal distention
Feeding residuals
Bloody stools
Normal or non-specific radiologic signs
6. Bell’s Stage 2:
Definite Disease
Moderate systemic symptoms
Pneumatosis intestinalis or portal
venous air on radiology studies
Blood test results showing metabolic
acidosis or thrombocytopenia
7. Bell’s Stage 3:
Advanced Disease
Severe systemic illness with unstable
vital signs or low blood pressure
Severe abdominal distention or
peritonitis
Pneumoperitoneum or air in the
abdominal cavity
Worsening blood test results,
respiratory acidosis or disseminated
intravascular coagulation (DIC)
8. Treating NEC
NEC can develop at any time in the absence of
medical negligence, but once it is suspected,
treatments must be started immediately to
minimize the extent of damage to the bowel.
Treatment consists of supportive care including:
Bowel rest by stopping feedings
Decompression of the intestines with
intermittent suction
Fluid and electrolyte replacement
Blood pressure support and antibiotic therapy
If the destruction is not halted, it can lead to bowel
perforation requiring immediate surgery, bowel
resection, colostomy placement, or even death.
9. Understanding
Your Rights
If your infant had NEC and you believe he or
she was not properly treated and that led to
a permanent intestinal injury or wrongful
death, you may want to contact
an experienced medical malpractice
attorney for additional information.
GENERAL MEETING | 2020
10. We Maintain Offices in Philadelphia, Pittsburgh,
New Jersey, Delaware, and New York. For Cases Outside of These
States, We Work With Local Attorneys as Applicable.
Call (800) 243-1100 to schedule a consultation.