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Narrative Writing Worksheets Free Downloa Narrative Writing Worksheets Free Downloa

Tay Sachs Disease Essay
Tay Sachs is an incurable genetic disease that affects the central nervous system. It is a rare disorder
that occurs chiefly in infants and children, especially those of the Jewish heritage. It is characterized
by a red spot in the retina, paralysis, gradual blindness, and loss of muscle movement.
Tay Sachs can only be inherited, which means it is passed from parents to child only. The process
begins in the fetus, very early in pregnancy. However, the disease does not become physically
apparent until the child is several months old. Tay Sachs is caused by the absence of a vital enzyme,
called the Hex A gene, which is in chromosome 15. This gene plays an important role in the nervous
system. It breaks down the fatty substance called ... Show more content on Helpwriting.net ...
Parents who suspect they might be at risk are strongly encouraged to be tested before pregnancy.
Pregnant mothers can have their unborn babies tested for Hex A deficit that causes Tay Sachs. If these
tests do not detect the Hex A gene, the baby has the Tay Sachs mutation. If the tests do detect the Hex
A gene, then the baby is perfectly healthy. Between the 10th and 12th weeks of pregnancy, an
expectant mother can get a chorionic villus sampling or CVS. In this procedure, a small sample of the
placenta is drawn into a needle or small tube for analysis. Between 15 18 weeks of a pregnancy, an
expecting mother could have an amniocentesis to test for the Hex A mutation. This test involves a
needle that is inserted into the mother s belly to draw a sample of amniotic fluid that surrounds the
fetus. Children are usually tested for Tay Sachs after having hearing, sight, and movement problems.
The disease can be identified by a doctor through blood tests and screening.
Children affected by Tay Sachs disease are born seemingly normal and develop like any other child in
the first three to six months of life. Throughout the next month, and sometimes even years, the baby
will progressively lose the ability to see, hear, and move. The child will develop a cherry colored red
spot in the back of the eye and they lose or never even gain important motor and mental skills. The
child will stop smiling, crawling, sitting, turning over, and reaching for things. By
... Get more on HelpWriting.net ...

Human Impact On Humans And Chimpanzees
The chimpanzee is one of the most interesting mammals on this earth. These animals are the cousins
of humans. According to the National Geographic chimpanzees share 98% of our DNA . This in
relative terms make humans and chimpanzees very alike, we are them and they are us. The
chimpanzee population inhabitants Africa. Although many believe that chimpanzees are monkeys,
they are great apes. (savethechimps.org). The chimpanzee population in the last few years has
diminished drastically and this has cause them to become endangered species. Like humans the
chimpanzees lives in communities they also have a hierarchy, and they consume a diet of vegetables,
meats and fruits. (savethechimps.org).
Although humans and chimpanzee are considered relatives, humans are one of the biggest threats to
the great ape. Humans are one of the biggest reasons the chimpanzee are endangered. According to
World Wildlife poaching is one of the biggest threats. Poaching means to hunt, kill and then consume
the chimpanzees. This gruesome act is usually done by wealthy urban residents who desire to eat
bushmeat. This is an expensive luxury that is costing the chimpanzee their lives and is significantly
decreasing their population. Another unlawful act happening to these great apes, their young babies
are being captured and sold for recreational pets.
The Scientific American discuss the illegal acts of the criminals who hurt these beautiful animals.
Even though many chimpanzees are captured to be

Employment and Workforce Diversity Essay
3RTO ACTIVITY 1
1.1: 3 organisation benefits of attracting and retaining a diverse workforce
In this era of economic globalization, many companies are making efforts to achieve workforce
diversity, which aims to employ workers from different backgrounds to provide tangible and
intangible benefits to the organization. Understanding the advantages of workforce diversity helps an
organization to establish with a competitive edge. This can include employing workers with cultural
and language skills that can lead to greater reach for the business.
3 organisation benefits of attracting and retaining a diverse workforce
1: Increase in Productivity
Workforce diversity can bring about an increase in productivity and competitive ... Show more content
on Helpwriting.net ...
When companies outsource, that reduces the need for recruiting new employees. The human resources
department will have to shift resources away from recruiting for the outsourced functions, and focus
on supplying employment candidates for the company s core business units.
3: Competition:
Companies within the same industry are competing for qualified candidates to ensure future growth.
There is competition in the recruiting end of your business just as there is in selling products. You
need to analyze what your competition is offering new employees, and try to develop a competitive
package to lure in the talent that you need.
2.1 Describe the benefits of at least 3 different recruitment methods
1: Internal Recruitment: benefit is cheaper and quicker to recruit. People are already familiar with the
business and how it operates. It can be motivating as it provides opportunities for promotion with in
the business. Organization is already aware of the strength and weaknesses of candidates. Easy to pick
up the best talents within an organization. It builds a long relationship with employees.
2: External Recruitment: The benefit is the outside people bring in new ideas. You get a larger pool of
workers from which you can select the best candidate. Candidates will have a wider range of
experience. Uniqueness in employees worked for different companies

William Faulkner s Literary Analysis
William Cuthbert Faulkner was an American writer, born on September 25, 1897 in Oxford,
Mississippi. He died on July 6, 1962, of a heart attack. Faulkner is credited with many literary works
including novels, short stories and poetry. He had a tendency to focus his writings on families, time,
sex, the past and the south where he was born. He created voices for children, criminals, the mentally
unstable and the dead (Faulkner, 2013). In Faulkner s A Rose for Emily, he elucidates the effect of
time versus tradition and looking at the world in a vividly obscured view through symbolic
representations anchored to a rose and a house.
This house, like Emily Grierson, represented the wealth and tradition of the Old South. Built in 1870s,
the exterior ... Show more content on Helpwriting.net ...
The rose is most often thought of as a symbol for love in which case Homer is the representation the
rose or love for Emily. Her father thought no man was good enough for her or for the Grierson family.
Therefore, she was never able to experience desire or the rose of love until she met Homer. However,
there is another meaning of rose to consider. In Medieval times the rose was used as a sign of silence
or secrecy (Lowe, 2001, Feb 14). A rose was hung from the ceiling at a meeting of secret societies
indicating a demand for discretion. The rose in the title of the story could therefore stand for Emily s
secret; that is Homer her rose whom she cherished, loved and kept to herself even after his body was
corrupted by the decay of

Cause And Symptoms Of Alzheimer s Disease
What is Alzheimer s disease?
Alzheimer s is a disease that erases the memory of people quietly. People will have difficulty in
memorize recently happened events rather than the things happened years ago.
Changes in the brain:
It will damage the brain by a protein which will abnormally form amyloid plaques and tan tangles.
The damages to the brain probably exist more than 10 years before cognitive problems occur which
means it is symptom free during preclinical stage. At beginning, damage happens in hippocampus,
affects the forming of memories. Then, after more neuron is died and more parts of brain are affected,
the brain began to shrink. Lastly, damage spreads widely and the shrinkage can be seen obviously.
Signs and symptoms
Memory problems ... Show more content on Helpwriting.net ...
The cancer drug works as a completely different role in the brain. It is now trying to reduce the high
level of abnormal protein amyloid beta (A beta). It will change the behavior of a cholesterol carrying
protein (ApoE).
When tested on mice that brain was full of A beta, only hours after, the A beta level fell. Later on, 25%
reduced after hours and 75% reduced after 14 days. The reverse of A beta level was significantly. The
testing mice also started to be no longer have memory loss since mice used to have Alzheimer s were
able to building nest like home again. Another testing is about sense of smell, the testing mice became
familiar with the kind of odor that put several time. From the changes of these testing mice, it is
clearly that bexarotene may eleventh or even reverse the happening of Alzheimer s. Since this drug is
used to treat T cell lymphoma, so it is FDA approved. This means it will be easier for therapists to
work with this drug. However, although this cancer drug worked on the mice, transform the drug for
human uses is the most difficult step in drug development process. Therefore, it is hard to say whether
bexarotene will work for treating

Homosexuality In Ancient Greece
In the wake of the 2016 presidential election and the stunning reality for many LGBT people of the
country electing an incredibly anti LGBT president and vice president, there was one area of
redemption for the LGBT community. Kate Brown, who is bisexual, became the first openly LGBT
governor (Phillips). For LGBT people, representation is a huge step forward for voices to be heard and
for equality to become a reality and to have an openly bisexual woman in an influential leadership
position, is important for the same reasons for the rest of the LGBT community, but also because of
how few bisexuals are out of the closet. The Pew Research Center has found that 71% of lesbians and
77% of gay men are out to all or most of the important people ... Show more content on
Helpwriting.net ...
On February 21, 1903, The first New York anti gay police raid takes place at the Ariston Bathhouse.
Police detained 60 men, and arrested 14 ( A History of the LGBTQA Movement ). Same sex attraction
and acting on this attraction was seen as a dangerous threat to the community that called for police
presence in the early twentieth century in the United States as seen through this raid. In the same
article from 1934 to 1968, the Motion Picture Production Code, known as the Hayes Code, prohibited
depiction of homosexuality in film ( A History of the LGBTQA Movement ). Not only was there no
representation for LGBT people in film for this long period in twentieth century America, it was
illegal to for movie makers to depict homosexuality which leads to homosexuality becoming even
more taboo than how cultural attitudes around it create. In 1945, After the Allied forces liberated the
concentration camps, those interned for homosexuality are not freed, but required to serve out their
full sentences because of the German law outlawing homosexual behavior ( A History of the
LGBTQA Movement ). The Holocaust is often seen as a major injustice in Jewish history, but it also
had a huge impact on lesbians, gay men, and bisexuals who were found guilty of homosexuality and
even though they faced the same horrors of the Holocaust that Jewish people did, they did

Essay about Cholera Project
1. Models are analogies that allow us to clarify hypotheses proposed explanation of relationships
between. What roles do models play in testing hypotheses?
Models provide the physical testing and proof of a hypothesis by exploring the extent to which the two
factors relate within the given hypothesis. It puts a theory into action, to see if the theory is corrected
causes and effects.
2. What did the humoral model of disease propose as the cause for cholea?
The humoral model of disease said that disease was caused by an imbalance in one or more of four
humors or fluids in the body: blood, phlegm, black bile, and yellow bile. Physicians would decide on a
treatment based on what they thought was the cause of the ... Show more content on Helpwriting.net
...
2. Why weren t Snows ideas about cholera accepted at this early date? 3. Explain why cholera
outbreaks are more consistent with contamination of water than air. 4. Given that cholera outbreaks
are more consistent with contamination of water that air, why did the miasma model persist? 5. How
did Snow s experimental research on anesthesia help him design a new model for the cause of
cholera? 6. Why would evidence of cholera in people living side by side, differing only in water
supply, provide critical evidence? 7. When was the germ theory of disease proposed, and on what
basis?
Part three:
1. Why was it useful to be able to verify the source of the water? 2. Why would a neighborhood served
by two different water companies be more useful for testing Snow s hypothesis than two
neighborhoods each with their own source? 3. Epidemiologists often draw causal webs to illustrate the
interrelationships among biological, social, and environmental variables that contribute to disease
outbreak. Based on what you have learned so far, what variables should be included in a causal web
for cholera? 4. Snow considered his conclusions about cholera to be inferences from observations
whereas the reviewer from the medical journal considered these to be conjectures. What is the
difference between inference and conjecture?
Part four:
1. The basic questions of epidemiology focus on the

The Effects Of Music On Our Country Today
Music in today s day and age has the ability to be a very pervasive form of media. There is an
indisputable truth that media has the ability to effect the masses. But, the effect of music and the
message it is sends to its listeners is not always a positive one. I am aiming to describe how sexism in
music is an epidemic in our country today. I ll also be comparing and contrasting different music
genres, to see if certain types of music are better or worse than others. A common phrase in media and
advertising is Sex Sells , but at what cost?
Before examining sexism in the different genres, I d like to take an in depth look at the visual side of
the music industry. Music is an auditory medium, but there is an obvious visual side to its market as
well. Music videos became popular back in the early 80 s thanks to MTV. Steven A. Seidman wrote an
article titled Profile: An investigation of sex‐role stereotyping in music videos , in which he conducted
a study, and discovered that male characters were portrayed as adventuresome, domineering,
aggressive, violent, and victimize, while females were depicted as affectionate, dependent, nurturing,
and fearful than males. He also found that a large percentage of female characters wore revealing
clothing and that they initiated and received sexual advances more often than males. (Seidman) What
type of message does this send to the general public? And how does this portrayal influence
individuals? Another study aiming to answer

Misogyny In Antigone
Antigone as a Greek Feminist
The strong female protagonist in the play Antigone, is Antigone herself, who is portrayed as a
powerful woman, making the play have feminist critique to it.
There is no direct point in the drama that Sophocles makes it clear that Antigone is not being treated
with the respect that she deserves based on the situation that is happening to her. There is sexism and
misogyny as Creon gives Antigone a harsh and unfair sentence due to the crime she has committed.
Creon exclaims, If she can thus, flout authority unpunished, I am woman, she the man. Creon openly
and publicly disregards Antigone as a woman; as a king Creon feels the right to be able to do this to
Antigone. Part of the reason that Creon has sentenced her ... Show more content on Helpwriting.net ...
As a result of the fact, he ends up completely over reacting to something that though is legal. A
disregard of his rule should be met by a ruler with some sort of compassion and empathy, considering
Antigone s situation. Although, she committed a crime and went against the order of the king, her
illegal actions were of a civil matter and did not compromise anyone s safety and well being, destroy
anyone s right to property, or create a situation that might in any way harm another citizen. Her crime
was of a nonviolent nature, and the justice system should punish her accordingly. Creon s desire to
prove his man hood was the impetus for making such a rash and visceral decision on how to handle
Antigone s crime rather than taking a set back and assessing the situation in a more intellectual and
humane perspective. Had Antigone been a male who created the same disobedience against the king,
Creon may not have overreacted nearly as much because his ego as a man would not have been as
embarrassed. Creon s misogyny is evident when he exclaims, what evils are not wrought by anarchy!
She ruins state, and over throws home, she dissipates and routes the embattled host. Sophocles
portrays the word anarchy as a woman, and when he continues to describe the word anarchy, he does
not use the pronoun

Colombian Culture VS American culture
Culture can be seen from the interaction of many things such as history, activities and developments.
It is also represented in the form of people live. Living in two different countries is a unique
experience that gives you a new way of thinking. In my case I have lived in Colombia and now in the
United States. Despite bearing some minor similarities, the differences between this to countries are
notable in geography, festivities, economic and food. Colombia is located in South America, is divided
into five regions: Andina, Pacifica, Caribe, Amazonica and Orinoquia. It has thirty two states.
Colombia is bordered to the north by Panama, to the east by Venezuela and Brazil, south to Peru and
Ecuador, and to the west by the Pacific Ocean. Colombia is the only South American country with
coastlines on the Pacific Ocean and the Caribbean Sea, which has several islands as the Archipelago of
San Andrés, Providencia and Santa Catalina. Colombia has the largest number of species per unit area
in the world, total is the second most diverse country in the world after Brazil. United Sates is located
in North America where its 48 states and Washington DC, the capital district. Between the Pacific and
Atlantic Oceans, bordered by Canada to the north and Mexico to the south. The state of Alaska is in
the northwest of the continent, with Canada to the east. The state of Hawaii is an archipelago in the
Pacific Ocean, and is the only U.S. state that is not in America. The country also

Children Need a Healthy Breakfast
How Not Having a Healthy Meal in the Morning affects Children America is often referred to as the
most developed country worldwide where everything is easily accessible to residents. Recent research
has shown that 50 million Americans lack access to safe and nutritious food in the home, 17 million of
which are children. A perfect example of this can be seen in the recent film, A Place at the Table
where. Rosie, an 8 year old girl living in Colorado expressed the difficulty that she finds in
concentrating in school due to stomach discomfort. According to Rosie she spends most of her time in
class fighting her cravings while uncontrollably thinking of apples, oranges and bananas. Rosie is just
one of the 17 million children who does not have desert at nights. Most times when you picture a
starving child, America is the last place to come to mind. Being one of the most economically
advanced countries in the world, America is said to be the land of dreams and opportunities and the
home of proud citizens. However, in the recent film A Place at the Table , this idea was tarnished. The
film sought to expose the presence of hunger in the United States through the documentation of the
life of Americans who are unable to afford food. Jeff Bridges took on the role of a devoted advocate in
the battle against starvation in America. The US Department of Agriculture s statistical findings
revealed that out of the 50 million American residents that do not consume healthy nutritious

Is Yours a Learning Organization
TOOL KIT
Is Yours a Learning Organization?
Using this assessment tool, companies can pinpoint areas where they need to foster knowledge
sharing, idea development, learning from mistakes, and holistic thinking.
by David A. Garvin, Amy C. Edmondson, and Francesca Gino
L
Daniel Chang
EADERS MAY THINK that getting their organizations to learn is only a matter of articulating a clear
vision, giving employees the right incentives, and providing lots of training. This assumption is not
merely flawed it s risky in the face of intensifying competition, advances in technology, and shifts in
customer preferences. Organizations need to learn more than ever as they confront these mounting
forces. Each company must become a learning ... Show more content on Helpwriting.net ...
Our instrument enables your company to compare itself against benchmark scores gathered from other
firms; to make assessments across areas within the organization (how, for, example, do different
groups learn relative to one another?); and to look deeply within individual units. In each case, the
power is in the comparisons, not in the absolute scores. You may find that an area your organization
thought was a strength is actually less robust than at other organizations. In effect, the tool gives you a
broader, more grounded view of how well your company learns and how adeptly it refines its
strategies and processes. Each organization, and each unit within it, needs that breadth of perspective
to accurately measure its learning against that of its peers.
Building Blocks of the Learning Organization
Organizational research over the past two decades has revealed three broad factors that are essential
for organizational learning and adaptability: a
Our tool is structured around the three building blocks and allows companies to measure their learning
proficiencies in great detail. As you shall see, organizations do not perform consistently across the
three blocks, nor across the various subcategories and subcomponents. That fact suggests that different
mechanisms are at work in each building block area and that improving performance in each is likely
to require distinct supporting activities. Companies, and units within them,

Maria Theresa Research Paper
Maria Theresa was born in Vienna, Austria at the Hofburg Palace on May 13, 1717 and was the
second child and eldest daughter of Charles VI, who was the Holy Roman Emperor of the Holy
Roman Empire and his wife, Elisabeth Christine of Brunswick Wolfenbüttel. Since Charles VI was the
last remaining male heir to the Habsburg throne as his only son and sole male heir and Maria Theresa
eldest brother died shortly before Maria was born. So Charles VI reformed the Salic Law, which
prevented any heir who were female to succeed her father as Charles VI feared that he might not
produce a son. In 1713 Charles VI issued the Pragmatic Sanction, which ensure his eldest daughter the
right to take over and succeed the throne and inherit his united lands when he died. During 1720
Charles VI worked endlessly to earn supports for the Pragmatic sanction from his crown lands and
over time they reluctantly agreed to honor and uphold the sanction. Charles VI was often encouraged
by Prince Eugene who was his most trusted and loyal adviser of Savoy to marry Maria off to a very
powerful prince but instead, Charles VI allowed his daughter to be one of the few people in her ...
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Maria Theresa was only 23 years old when she succeed the Habsburg throne. After Maria Theresa
gained the titles of Holy Roman Empress, Empress of Austria, and Queen of Hungary the Austrian,
Netherlands, Bohemia, and Hungary who were her subjects were quick to accept Maria Theresa as
their empress. But Maria Theresa immediately faced resistance to her succession from European
powers especially Prussia who had previously agreed to her father s Pragmatic Sanction. Under the
leadership of Frederick II who was King of Prussia, the Europeans powers formed a coalition against
Maria Theresa which was call the War of the Austrian Succession. The war ended in 1748, and Maria
was forced to accept the loss of her three Italian territories to France and let Prussia keep the province

The Importance Of Multilingualism As An Official Language
Every nation should set multilingualism as their main objective. There are many benefits both at an
individual level as well as at state level for people to be multilingual. Firstly, knowing multiple
languages helps us to adapt into and interact in this globalised world we live in. Secondly, being able
to express ourselves in a language we identify ourselves most with, and have the strongest knowledge
of, is a human right.
It is important to make a distinction between a national language and an official language before
discussing any further. National language is a language associated with a particular country where it is
recognised as a symbol of national identity (Joan Swann, 2004) whereas an official language can be
defined as a language which is used for political, legal and administrative communications within a
given political territory. (Joan Swann, 2004) This essay will focus on national languages and their
importance across the globe from small communities to national level without overruling the
importance of having official language(s) helping to run governments.
Due to globalisation, the world nowadays is significantly interconnected economically,
technologically and culturally. Even though globalisation is not a new phenomenon, and can be argued
to have started already in the 1500s when the transatlantic exploration and consolidation of European
hegemony began, the pace and the scope of it is greater than ever² (Ruth Wodak, 2011). Consequently,
we

The President Of Honeywell Fm T
Describe who you gathered the information from for the paper? What is their job role? How have they
been involved in the strategic planning process at the company?
The President of Honeywell FM T was the subject of the interview for the following information. The
President of Honeywell FM T is the leader of the organization and currently leads over 3000
employees. Even though, many individuals are involved and provide valuable input for the plan, the
president is the final decision maker, when it comes to the strategic planning and ultimately
responsible for the path forward. In the end, he is accountable for the strategy and is evaluated through
his performance review, based on the actions taken and achieved by the organization. Therefore, he
ensures that he is a key part of the defining, planning, scheduling, and control of the plan. The plan is
created based on alignment with the goals of Honeywell Corporate, the president then flows his goals
to the team, for the goal of drafting a solid plan for the future of the organization.
Describe briefly the company. What it does? Who are its customers and markets (in general terms)?
Honeywell itself is an extremely large organization spanning across numerous business divisions. The
division of focus, is a part of Honeywell s Aerospace Division, known as, Federal Manufacturing and
Technologies (FM T). Honeywell FM T is currently the contractor that manages the National Security
Campus in Kansas City, MO and Albuquerque, NM.

Who Is Van Gogh A Savage
Since the very young age Van Gogh s art caught my attention. Unique and expressive, Van Gogh
created his pieces to be representations of his mental work and experience. In his painting Dutch
master achieves architectural effects by putting extremely thick paint applications. From my personal
experience it is amazing (I ve seen couple of his works in Russian Hermitage) how he didn t fear the
canvas or paints. People of his epoch, when comparing his works to Monet s probably thought that
Van Gogh is a savage. But this pure energy of a savage had passed through generations and lives today
through many reprints and we study it today. But Van Gogh wasn t just a savage, he was a master, but
he achieved this state of perfection uniquely,

Essay On Circus Hotel
ENTER THE WORLD OF MAGIC THROUGH MAGIC CIRCUS HOTEL, DISNEYLAND PARIS
The Magic Circus Hotel, near Disneyland Paris, managed by Vienna International Hotels and Resorts,
is an excellent starting point for various excursions to Paris and its vicinity, and a convenient base
featuring a wide range of accommodation units, entertaining and commercial facilities. The hotel is
adapted for a pleasant stay for any type of traveller, offering to its guests everything one might need,
whether it is a peaceful environment, comfortable rooms or apartments, business centre or entertaining
zone.
Besides the quality of service, the hotel is distinctive by its unique design
Once you enter the Magic Circus Hotel through an entrance featuring a circus tent, ... Show more
content on Helpwriting.net ...
The impression is, however, that small kids are most happy in the hotel, due to its multi coloured
ambiance, handful children s programs and a variety of playgrounds. But it is also a great place for us
adults as well. We are all Big

Factors Affecting Second Language Acquisition
Different factors can affect second language acquisition in ELLs. It is important to determine what
may hinder an ELLs students success in a K 12 setting. One issue is negative transfer and the
differences between the L1 and English may cause an interference. However, that is just one of the
issues. This research addresses the impact school environment may have on SLA.
Literature Review
.
School Environment School environment does have an effect on a student acquiring language. Factors
such as students feeling stigmatized and lack of support for students and teachers can have negative
results.
Yi (2013) conducted a case study of a Korean high school student named Hoon (a pseudonym) in a
United States school. Hoon felt his ESL(English as a Second Language) status stigmatized him. He
felt embarrassed or that he was losing face because he was an ESL student. Hoon reported some his
classmates made fun of him for being in ESL which further contributed to his feeling of
stigmatization. Because of his negative feelings he had his ESL teacher move him from Beginning
ESL to Advanced ESL skipping over Intermediate ESL. However, he repeated Advanced ESL three
times. His teacher attributed his difficulties in English to him skipping over Intermediate ESL. Yi s
study of Hoon also discovered his stigmatized status was having an effect on his academic literacy.
For example, when he wrote essays he often wrote in long sentences, because he thought that is what
the

Overexpression Case Study
p16INK4a overexpression in pre malignant lesions
Several pieces of evidence suggested that the ability to bypass senescence is the main molecular
mechanism involved in the progression of pre malignant to malignant cells (Braig 2005; Collado
2007). This hypothesis is based on the concept of oncogene induced senescence, which was
established after demonstration of p53 and p16Ink4a mediated senescent like arrest in response to
expression of oncogenic Ras in normal primary cells (Collado 2007). This event (OIS) has been
considered as highly possible mechanism to prevent proliferation of incipient cancer cells (Sinha
2015). Consistent with this concept, senescent cells have been shown in a number of different benign
lesions, including ... Show more content on Helpwriting.net ...
p16INK4a methylation could thus have a diagnostic application; it can be used in the differential
diagnosis from pre malignant and malignant lesions (Feng 2015).
OIS is emerging as a potent cancer protective response to oncogenic events, serving to eliminate early
neoplastic cells from the proliferative pool. Kuilman et al. (2008) reported a unique role of interleukin
6 (IL 6) in OIS of cancer cells. Using combined genetic and bioinformatic analysis, they found that
OIS was linked specifically to the activation of an inflammatory transcriptome. Induced genes
included IL 6, which upon secretion by senescent cells acted mitogenically in a paracrine fashion
(Kuilman 2008). IL 6 was also required for the execution of OIS, but in a cell autonomous fashion. Its
depletion caused the inflammatory network to collapse and abolished senescence entry and
maintenance. They also demonstrated that C/EBPβ cooperated with IL 6 to amplify the activation of
the inflammatory network, including IL 8. In human colon adenomas, IL 8 specifically colocalized
with arrested, p16INK4a positive epithelium. They proposed a model in which the context dependent
cytostatic and pro mitogenic functions of interleukins contribute to connect senescence with an
inflammatory phenotype and cancer. The role of role of IL 6 in OIS has been confirmed by later
studies

Catcher In The Rye Alienation
No one likes being alienated, feeling alone, nor isolated from the outside world, yet so many people
are. At every glance someone takes, they will always find someone with first hand experience of
feeling left out from society due to events in their life, their own cause to leave themselves out, or
society alienating them. This is important to understand because there are so many people alienated
without any knowledge on why it is happening to them nor how it will affect them in the long run.
Even as much as people in real life have to deal with alienation so do the characters in J.D Salinger
remarkably told novel, the Catcher in the Rye. The Catcher in the Rye illustrates characters with a first
hand experience of alienation and the affects ... Show more content on Helpwriting.net ...
For example, when Holden was in New York, he goes from one bar to another trying to find a waiter
that would give him alcoholic drinks. After being left alone at the Wicked Bar, Holden sat at...[the] bar
till around one o clock or so getting drunk (149). All by himself, Holden goes into a marathon of
drinking until his gut forces him to leave. Being alienated, an individual will try to find ways of
coping with it even if it is not the correct way. In another quote given from, Growing Up Lonely:
Examining Teen Alienation by Linda Lyons, she recorded an experiment to see the percentages of
actions taken by people who struggle with alienation. The data indicates how people who are alienated
from the outside world, 25%... [of them] said they have tried marijuana, [while] 8% who are not
alienated have also tried marijuana. Furthermore, stating the fact that there is an increasing percentage
in risky behavior for the people who are alienated than the ones who are not. Once alienated, the
individual can become a danger to themselves causing irreversible damages, to both their mind and

David And Goliath Beliefs
Contest of David Goliath: The Philistine army had gathered for war against Israel. David volunteered
to fight Goliath. As Goliath moved in for the kill, David reached into his bag and slung one of his
stones at Goliath s head. Finding a hole in the armor, the stone sank into the giant s forehead and he
fell face down on the ground. David did the right thing in spite of discouraging insults and fearful
threats. Only God s opinion mattered to David.
Wisdom of Solomon:
Good Fortune of My cup runneth over: I have more than enough for my needs though interpretations
and usage may vary. Notably, it can be employed sarcastically to indicate that someone, e.g. one s
host, is being less than generous. Comes from the Hebrew Bible
Relations between ... Show more content on Helpwriting.net ...
Moses: Moses was born in a time when his people, the Israelites, an enslaved minority, were
increasing in numbers and the Egyptian Pharaoh was worried that they might ally with Egypt s
enemies. God sent Moses back to Egypt to demand the release of the Israelites from slavery. Moses
said that he could not speak with assurance or eloquence, so God allowed Aaron, his brother, to
become his spokesperson. After the Ten Plagues, Moses led the Exodus of the Israelites out of Egypt
and across the Red Sea, after which they based themselves at Mount Sinai, where Moses received the
Ten Commandments
Prodigal Son: a father has two sons. The younger son asks for his inheritance before the father dies,
and the father agrees. The younger son, after wasting his fortune (the word prodigal means wastefully
extravagant ), goes hungry during a famine, and becomes so destitute he longs to eat the same food
given to hogs, unclean animals in Jewish culture. He then returns home with the intention of repenting
and begging his father to be one of his hired servants, expecting his relationship with his father is
likely severed. Eventually, they still celebrate the return of the younger son because he was lost and is
now

Essay on Peace Like a River, by Leif Enger
Consequences come from choices individuals make, such as waking up in the morning at a specific
time in order to avoid traffic. However, even if the decisions are not made by the individual, they still
have to suffer the consequences of those decisions made by others. Take, for instance, the choice that
someone makes to drink and drive while under the influence. If that person kills someone, then his
decision impacts the lives of everyone involved and not just himself. A theme in Peace Like a River,
by Leif Enger, is that people must accept the consequences of their actions because it influences the
direction they go in life. This theme is developed through the character of Jeremiah, the conflict
between Davy and the law, and the symbolism ... Show more content on Helpwriting.net ...
Jeremiah s intervention is observed when he insists, breathe ....breathe! .... Reuben Land, in the name
of the living God I am telling you to breathe (Enger, p. 3). Jeremiah ordered his son to breathe, even
though twelve minutes had passed since he was dead; however, when he orders Reuben to come back
to life, he says that in the name of God he must resuscitate. Reuben was not destined to live, and
because his father s choice went against what was supposed to happen, Reuben must live an asthmatic
life that limits what he is able to do. Ultimately, Enger portrays how all decisions have consequences,
and many times the results will not be the expected ones.
The conflict presented between Davy and the law depicts that people must take responsibility for the
consequences of their actions. Davy is Reuben s independent older brother. While only seventeen
years old, he always gives the appearance of an adult fully capable of caring for himself. He has a
mind of his own and does not want anybody telling him what to do. Davy s independence seems to
follow his dad s advice, which is shown at the end of the first chapter when Jeremiah tells his children,
We and the world, my children will always be at war. Retreat is impossible. Arm yourselves (Enger,
p.4). Jeremiah advises his children that life is difficult, and

Frederick Douglass and Benjamin Franklin
Frederick Douglass and Benjamin Franklin
American success history recognizes the contributions made by two of its renowned leaders. The two
are regarded as heroes despite the obvious differences between them abound. The two figures are
regarded with comparable amounts of reverence even though they lived their lives in different ways.
Nevertheless, both Benjamin Franklin and Fredrick Douglas gained their status through treading
pathway of hard work. This paper, therefore, seeks to discuss the experiences that shaped the lives of
both Franklin and Douglas. It also seeks to analyze the life of Fredrick Douglas as presented by John
Stauffer. In comparing the two personalities, I will lay much emphasis on the role education played in
making ... Show more content on Helpwriting.net ...
He was in early 1817 on one of the plantations of Maryland. The identity of Douglas s father and
exact date of birth is not well known, but it is assumed to be a white man from a family who owned
his mother. Harriet Bailey originally named his son Fredrick Bailey but, unfortunately, he parted with
his mother while still young and was raised by other slaves in the plantation (Douglas 67).
Fredrick Douglas went to the North and was married to Anna Murray, a black woman who married
him in New York City. They then fled to New Bedford where Douglas found work as a laborer. In
around 1841, Douglas had an opportunity of attending the Massachusetts Anti Slavery society which
was held in Nantucket. It was during this time that he got on stage and delivered a speech which
moved the crowd. He delivered his life as a slave with passion such that he was encouraged to
dedicate himself in speaking against slavery (Douglas 45). This marked the beginning of his activism
in northern states. For instance, in 1843, he was nearly killed while giving out a speech in Indiana.
During the 1850s, Douglas was in the fore front in abolishing slavery, which was threatening, to tear
the country apart. In the beginning, Douglas felt that John Brown s anti slavery ideas and plans were
suicidal and he refused to engage in a raid on Harper Ferry. Brown s activities saw him captured and
hanged, an act which

Sartre s Conception Of Human Consciousness
A question that continues to puzzle scholars (and Honors students, alike) is that of what defines human
consciousness. It would be simple to say that it is defined by one s awareness of itself and of its
surroundings. What makes the question so difficult to answer, though, is that consciousness is much
more than an acute awareness; it is the process of becoming aware, finding the purpose of our
consciousness, and building morals and intelligence from that awareness that entangles those who
search for answers in a web of utter confusion. In beginning my search for the understanding of
consciousness, I chose to look into the thoughts and beliefs of Karl Marx and Jean Paul Sartre. Marx
and Sartre are similar in their philosophy in that ... Show more content on Helpwriting.net ...
Starting with Sartre s existentialist point of view, consciousness is defined as being for itself. When we
are for itself, we recognize our consciousness, but also understand that we are incomplete (SparkNotes
Editors, 2005). This notion of being for itself is what makes clear Sartre s belief that existence
proceeds essence; we aren t born with innate traits, but rather, we create our consciousness. We are
free to choose how we will interpret our surroundings, what we will believe, and what type of
personality we wish to have in accordance to those beliefs and interpretations. Sartre further explains
that this freedom comes with heavy responsibility. Once we make a choice, we cannot make excuses
for ourselves or put the blame on someone or something else if the choice turns sour or ends up being
faulty; when we accept the freedom, we accept the full responsibility, too. If we fail to take up this
responsibility and live dishonestly about inevitabilities, such as death, or possibilities, we are living in
bad faith , as Sartre says. On the other hand, to live in good faith is to understand and acknowledge
that control of the outside world is not in our hands, yet to still take the responsibility and freedom of
choices that we have over ourselves. Living nobly in good faith may be what is troubling about
existentialism to some people, especially those who are religious. I believe that Sartre feels that
humans are innately good and have the

Clear Cell Carcinoma Case Study
Title: Clear cell carcinoma of thymus and thymoma. Abstract: we report a case of 63 years old man
affected by myasthenia gravis associated to two nodular lesions of thymic tissue and, after complete
thymothymomectomy, pathologic findings revealed a B3 thymoma and a clear cell carcinoma. Post
operative period was uneventful. The patient had no recurrence or metastasis after the first year of
follow up. Key words: thymic neoplasm; clear cell carcinoma; minimally invasive
thymothymomectomy; robot assisted surgery. Introduction The association of thymic epithelial cancer
(thymoma) and thymic carcinoma is extremely rare. Thymoma is often correlated to paraneoplastic
syndrome as myasthenia gravis (MG), where as carcinoma has frequently an aggressive and invasive
pattern. We describe the ... Show more content on Helpwriting.net ...
The patient had no recurrence nor metastasis after the first year of follow up. Discussion Thymic clear
cell carcinoma (TCCC) is a rare and aggressive variant of thymic carcinoma classified into high grade
category due to its poor prognosis: in a series of eight patients with a diagnosis of TCCC the median
survival was only 13 months (1). Other case series report always a poor disease free and overall
survival (10 15% at five years). TCCC is traditionally not associated to para neoplatic syndrome
(myasthenia gravis, pur cell aplasia), but symptoms, if present, are more frequently related to
aggressive behaviour or compression to surrounding structures. The diagnosis of primary thymic
carcinoma depends of exclusion of other sites clinically, especially kidney and lung, but also pancreas,
thyroid, larynx and salivary gland. For its rarity, are not available multimodal treatment and complete
surgical resection is still the best way to treat but is not always

The Outdoors Research Paper
I was in Galveston, riding in a speedboat going 100 miles per hour.We were fishing for King mackerel
50 miles off shore in the Gulf of Mexico. Suddenly, a rod was running out of line, it was my turn to
reel in. This was the toughest fight I had in my entire life. I want you to have this feeling as well as I
do. The outdoors was a great experience. Nature was the greatest thing about my trip. With the most
fun I have ever could . .The outdoors could be dangerous, but it could be a lots of fun.You can
probably see wild animals such as deer, birds, insects, and more. The trees will give you fresh air
instead of that gross house air you breath all the time.You can also take hikes in the outdoors down old
long trails. Nature could be lots of fun

How Does Amenabar Create Suspense
The others directed by, Alejandro Amenabar is a haunted house themed ghost story, which creates a
thrilling atmosphere as Amenabar emphasizes a combination of uncertainty, tension, suspense and
shock. Amenabar creates an atmosphere, which has the time and patience to generate a mood and
create mystery to the characters. The setting Amenabar has chosen is very cliché and fits into the
horror theme perfectly being a large house, which is trapped in fog. Amenabar also adds mystery to
the characters as the two children are extremely sensitive to light and can only confine in only the
dark. Amenabar let s the audiences use their imaginations to put the film together and make sense of
it, which is really what thriller/horror films need. Using different melodies and sound affects along
with different camera angles and viewpoints the opening scene of Grace screaming, the storage room
scene and the bedroom scene all support the evidence of atmosphere and suspense.
After the drawings follows up a shot of a an isolated house surrounded in fog, this ... Show more
The setting of the film is trapped in darkness; this of course is because the children are photosensitive.
However the darkness creates doubt for the characters and the audience what they can see occurring.
Nervousness rises as the characters become more paranoid and suspicious of what they call the others
in their house. The usage of light is particularly significant in the bedroom scene where both Anne and
Nicholas are in twin beds sleeping, when Victor who is seemingly messing around with the curtains
suddenly awakes Anne. Anne quickly wakes up Nicholas to tell him Victor has opened the curtains. In
result of the curtains being open we can now see the children s face and the audience can t see
anything in the background apart from shadows due to the

Personal Leadership Philosophy Paper
Abstract Leadership is essential to the success of any organizations. Strong and effective leaders must
have clarity of purpose and a compelling vision to propel organizations forward. Every leader has a
philosophy which is a founding principle for their belief. Successful leaders know their personal
leadership philosophy and know how to communicate it in everything they do. Leaders must know
who they are, their priorities, and their values. This paper will highlight my personal philosophy and
the attributes that aspires me.
The Christian Leader Christians can face obstacles on how to be an effective employee especially in a
superior position. Christians in management to me means I still can maintain my morals and ... Show
more content on Helpwriting.net ...
Being a transformational leader is great because they are visionaries and motivators. However, the
downside to being such a leader can lead to some disadvantages along the way which can go wrong.
Some situations under this leadership style can quickly change to actions where decisions can be made
abruptly out of emotions. Typically abrupt decisions can be detrimental to the people and can also
result in negative implications. Another weakness of this leadership style is employees being burned
out. Employees can easily become inspired and hopeful to attain goals under transformational
leadership but can feel the disadvantage when they are made to work long hours and obliged to go
beyond their normal tasks in order to achieve

Walmart Supply Chain Management System
WALMART
REATIL SUPPLY CHAIN MANAGEMENT System
Karan Dewan
300808446
Professor Jeff Parsons
Business Communication
BUSN 733 102
12th November 2014 Executive Summary
Wal Mart supply chain management system is one of the best in the world. Wal Mart emphasized the
need to reduce purchasing costs and offer the best price to the customer. The company directly
procured from manufacturers, by passing all intermediaries. For Wal Mart, its SCM methods yield
lower costs for products and inventory, better control over selection in its stores and the ultimate result
of lower prices that can be passed to customers, Trade Gecko said.(Alliance, 2014)
Wal Mart was successful in launching the new technologies in their supply chain management system
like Cross docking which makes sure that once the order is placed it is tracked from the warehouse till
it reaches the end customer. In this system, the finished goods were directly picked up from the
manufacturing plant, sorted out and then directly supplied to the customers. The main plan of Wal
Mart s SCM is providing good quality product to customers with lower price. In addition, Wal Mart
also plans to minimize it inventory quantities (University of San Francisco, 2010). In order to achieve
those plans, Wal Mart integrates manufacturing, suppliers, and warehousing together. Wal Mart
purchases the goods from very fast range of vendors. In order to get the right product at right place
and at right time they need to maintain a

The Chernobyl Nuclear Power Of Ukraine
Radiation Disperses after Nuclear plant Explosion in Northeast Ukraine On April 26th, 1986, the
disaster at the Chernobyl nuclear power plant in Ukraine dramatically changed the world s opinion
about using nuclear reaction for power. At 1:23am, reactor four exploded, releasing more than a
hundred times the radiation of the bombs dropped on Hiroshima and Nagasaki (Rosenberg, 2014). As
a result of the incident and producing fire, large amounts of radioactive material were consequently
released into the environment. The accident caused the largest uncontrolled radioactive release into the
environment ever recorded for any civilian operation, and large quantities of radioactive substances
were released into the air for about 10 days. This caused serious social and economic disruption for
large populations in Belarus, Russia and Ukraine (Chernobyl Accident, 2014). While the radiological
impact from this disaster was minimal outside of Russian and Ukraine, it did bring to light the risks
associated with the use of nuclear energy across the global stage. Over the next sixteen years, world
leaders devoted their attention to conducting reactor safety studies, as well as improving emergency
preparedness for public workers and these industries. Located in Northern Ukraine, the Chernobyl
nuclear power plant is situated just approximately 80 miles north of Kiev, and just over 12 miles south
from the Belarus border. The power plants first reactor became operational in 1977, with the

The Psychosocial Theory Of Play During The Life Stages Of...
My report paper is based upon Erikson s psychosocial approach in the dimension of play during the
life stages of infancy and early school age. Psychosocial approach interested me the most because it
involves every stage of development from infancy to death in which there is a psychosocial crisis that
the person has to overcome to successfully move to the next stage of development. These
psychosocial crises are viewed as tension which are a normal experience for each individual because a
person s competencies and the demands that are place upon them by society are not the same. Erikson
s view of play interested me more than Piaget and Vygotsky s which is why I chose to focus on the
psychosocial theory of play. According to Erikson, The play often not only represented the problem
but also offers a solution so that children experience some new sense of resolution and a reduction in
the tension associated with the conflict (Newman Newman, 2012, p. 214). Psychosocial is a
combination of interactions among biological, psychological, and societal processes which allows us
to understand that this approach has a multi disciplinary view. When a person has a positive resolution
to each crisis it helps the person become able to be successful in the following stages which is why it
is so important to be able to adapt. The way a person handles their life experiences also influences
how the direction of development occurs as well as the biological and societal aspects. These

Three Certainty Requirement
This question require us to consider the three certainty requirements and the circumstances in which a
valid trust is said to be properly constituted. The general requirement to create a trust is that if the trust
is properly constituted, it bind the settlor and be enforceable by the beneficiaries. On the other hand, if
the trust is not completely constituted, it will be ineffective as the general rule requires. Equity will not
be able to help because of two of its maxims equity will not assist a volunteer and equity will not
perfect the imperfect gift . The court will be prevented from coming to the aid of a volunteer
beneficiary regardless of how undesirable the outcome might appear.
i. Is this a gift in favour of the sister or a trust in favour of his friends? If it is a trust, has the settlor
sufficiently shown intention to subject the property to a trust obligation? An express trust is created if
only the settlor can show that he intended to subject the property to a trust obligation. It is necessary
for the settlor to show that he intend to create a trust instead of some other type of legal relationship,
e.g. gift, a power or bailment.
As Megary .J. put it in Re Kayford Ltd, the question is whether in substance a sufficient intention to
create a trust has been manifested . However, a trust can be created ... Show more content on
Helpwriting.net ...
To Brown Wilkinson in Re Barlow s Will Trusts Friends has a great range of meanings, indeed its
exact meaning varies from person to person. Some will include only those with whom they had been
on intimate terms over a long period, others would include acquaintances who they liked. Some would
include people with whom their relationship was primarily one of business, others would no. Indeed,
many people, if asked to draw up a complete list of friends, would probably have some difficulty in
deciding whether certain of the people they knew were really friends as opposed to

The Mind Controls Our Brain
For the last few years, with this significant progress in the field of neuroscience and the researches on
brain s study, there has been a huge modification of some statement that were considered as relevant
in the past such our brain controls our mind but, nowadays it s quite clear that science agrees the
contrary , which is our mind controls our brain and this can be elucidated by the fact that statistics
confirm that 75 98 % of physical, mental and behavior illnesses come from our thought life; 350
million worldwide people suffer from depression;40 million people in the U.S. suffer from anxiety and
disorders and there are more deaths from suicides than from car accidents. The interesting part of such
study is when the neuroplasticity ... Show more content on Helpwriting.net ...
This essay will demonstrate some of these facts: It will show first that positives thoughts build healthy
proteins in the brain, and secondary that negatives thoughts interfere one s ability to make wise
decision. The impact of healthy thought is obvious. The science has proved that human brain is wired
for beauty and for love (there is no room for the negative).Therefore when people are thinking and
choosing, they are causing genetic expression and that means that at that appropriate time the
production of proteins is happening and all these proteins grouped altogether form thought trees in the
brain. A human being is also a thinking being .Every time one is thinking; he is growing a physical
substance inside of the brain; he is actually changing the structure and function of his brain. So when
one s choosing to think life which is positives thoughts, he is building an extraordinary ability to
determine, achieve, and maintain optimal levels of intelligent, mental health, peace, and happiness, as
well as the prevention of disease in one s body and mind. If someone through conscious mind is able
to gain control of thoughts and feeling, by doing so, he gains the ability to change the programming
and chemistry of his brain. There are even more encouragement pieces about the plasticity of the
brain. For example, Universality believe logic and language are learned at fixed age, and someone
passed that fixed age, he can t learn. Plasticity research proves

Math Essay
I VE GOT A SECRET!
Learning outcome:
Upon completion student will be able to: * Given linear and exponential data, interpret the rate of
change within the given context. * Represent linear and exponential models as equations, tables,
graphs and verbal descriptions.
Scoring/Grading rubric:
Each question is worth 10 points.
Introduction:
Everyone has had some experience with gossip. In this lab, you will explore how well rumors (or
secrets) spread when this information is passed on to other people.
Scenario A: At noon, you get some great news but you need to keep it a secret. It s just too good to
keep to yourself; so 5 minutes after you get the news you call 2 friends and tell them, but swear them
to secrecy. ... Show more content on Helpwriting.net ...
How many people know your secret at 12:40 in Scenario A?
In Scenario B?
2. Describe the pattern of growth in the Number of people told column for both Scenario A and
Scenario B.
3. Describe the pattern of growth in the Number of people who know column for both Scenario A and
Scenario B.
4. Write an equation to find the Number of people told for any 5 minute interval(n) in
Scenario A.
5. Write an equation to find the Number of people told for any 5 minute interval in Scenario B.
6. Write an equation to find the Number of people who know for any 5 minute interval in Scenario A.
7. Write an equation to find the Number of people who know for any 5 minute interval in Scenario B.
Using the equations you wrote in problems 4 7, create an Excel spreadsheet with the columns 5
minute interval, Number of people told, and Number of people who know . Make sure your

spreadsheet matches your tables above before answering the following questions. 8. After how many
minutes would at least 100 people know in Scenario A?
In Scenario B?
9. According to the 2012 US Census, the population of NC is 9,752,073. Using Scenario B,

Selective Incorporation
The process of Selective Incorporation has been used in the nationalization of the Bill of Rights
conceived by the Federal Government and the Supreme Court. Discuss the process and what events
brought about the necessity of using this action. Be sure to include at least four (4) nationalizations of
Amendments from the Bill of Rights and the dates they were nationalized through the Fourteenth
Amendment, and a brief explanation of the 14th Amendment. Many amendments have been ratified
since the 18th century, and there have been many court cases of those amendments being violated such
as the freedom of speech and the 5th amendment and many others. We will further discuss some of
those cases and amendments and how they ve impacted our current lives ... Show more content on
Helpwriting.net ...
The State of Connecticut which happened in 1937. In 1935 Frank Palka broke into a music store and
stole a phonograph and began to flee on foot later being cornered by the authorities. Palka killed two
police officers and escaped being caught one month later. Palka was charged with first degree murder
but later being convicted with second degree murder and sentenced to life imprisonment. The state of
Connecticut appealed and obtained a new trial, this time Palka was found guilty of first degree murder
and sentenced to death. Palka appealed this under the fifth amendment and argued that he was
protected under double jeopardy which is being trialed for the same case twice and claimed it applied
to the state governments under through the Due Process Claim, which I mentioned earlier, of the
fourteenth amendment. Applying selective incorporation, the court decided Palka s conviction on the
premise of double jeopardy appeal was not a fundamental right. Palka was executed in Connecticut by
electric chair in the state of Connecticut on April 12, 1938. This case was later overruled by Benton V.
Maryland in the year 1969. The year the fifth amendment was

Essay about No One Would Listen
Review Essay No one would listen By Joseph Kiobbo, Newman University No one would Listen: A
True Financial Thriller. Harry Markopolos, ed. New Jersey: John Wiley and Sons, Inc. 2010. Pp. 345.
$17.35 (hard cover) This book brought out the failures of the Securities and Exchange Commission
(SEC) in one of the biggest Ponzi schemes in America s history, as orchestrated by Bernie Madoff.
Harry Markopolos caught up with Madoff s Ponzi scheme earlier on in his career and saw all the red
flags. There was no explanation of the continuous one percent yield in over forty five stocks that
Madoff dealt with. Madoff took advantage of the laxity by the SEC officials in failing to follow up
complains with an investigation, and the trust ... Show more content on Helpwriting.net ...
The employees and traders shrugged it off. As it would later turn out, Madoff s illegal investment
business was indeed subsidizing his legal trading operation. Among the charges to which Madoff
pleaded guilty in March were three counts of money laundering, which involved transferring millions
of dollars from Madoff s fraudulent business through his London operation to his legitimate New York
business. At least $250 million was transferred in this manner, according to the charges. In 2006 when
the SEC launched an investigation into Madoff s dealings it was from persuasion from Markopolos
that Madoff was running a Ponzi scheme and he was also a key source for the Mar/Hedge article. The
SEC also examined whether Fairfield Greenwich, a giant feeder fund, was properly disclosing the
extent of its reliance on Madoff. According to research by Harry Markopolos, it grew from as much as
$7 billion in 2000 to as much as $50 billion by the end of 2005. What had started decades before as a
small time recruiting effort by Madoff agents at country clubs had gone global. Massive international
institutions such as Grupo Santander, Fortis Bank, and Union Bancaire Privée were all funneling
billions sometimes through intermediaries to Madoff, lured by the call of steady 10% to 12% returns.
Even one of the world s biggest sovereign funds, the Abu Dhabi Investment Authority, ended up
sinking tens of millions of

Comparing Lord Of The Flies And Seize The Day Essay
First and foremost, the books Lord of the Flies by William Golding and Seize the Day by Saul Bellow
are related in concept, theme, and depth. In fact, these novels consist of characters that could relate to
one another in their personal struggles. Although the characters have much in common, their present
environment forces them in different ways to work and talk with people they don t enjoy being
around. Because of this, there is a common disposition of darkness. Despite their many similarities,
there are different themes present. In Lord of the Flies, the focus is on the boy s strange environment
that forces them to work together and evokes fear which doesn t turn out well for their prosperity. This
is because a couple of the kids make choices that wrongly affect the island s turnout. Similarly, Lord
of the Flies and Seize the Day consist of characters with darkness of the heart and mind, and these
people affect everyone around them. In comparison, these texts both consist of deplorable characters
that only look to benefit themselves. Conversely, Seize the Day centers around inner struggle and
accentuates that throughout the novel, and Lord of the Flies focuses on societal ... Show more content
on Helpwriting.net ...
Clearly, the novels share a common theme of characters who won t help those who need it. In addition
to this idea, Wilhelm from Seize the Day and Piggy from Lord of the Flies both have someone who
wishes to do harm to them. Jack constantly puts Piggy down and Dr. Tamkin takes Wilhelm s money
and runs off with all of it.
Lord of the Flies and Seize the day are extremely similar novels. They both have depth and characters
which have much in common with each other. Though they are very similar, they do have prominent
differences too that differ from the other text. Lord of the Flies focuses primarily on external conflicts
and societal collapse contrary to Seize the day which accentuates internal

Charles Lutwidge Dodgson
In Daresbury in 1832, Charles Lutwidge Dodgson, or better know as Lewis Carroll was born. He grew
up with several younger siblings who he told stories to, one of those being Alice in Wonderland . This
beautifully written story is about a ten year old girl named Alice who falls down a rabbit s hole into a
colorful world full of mad characters called Wonderland. England in 1865 has become part of the
victorian time period and along with it came many traits that set it apart. Throughout the piece, Carroll
challenges many traits of England s society and turns them into something that made this story so
unforgettable. Victorian etiquette, education for children, government, and drugs are just some of the
things Carroll brings in from his time period ... Show more content on Helpwriting.net ...
At the very ending of the book, the King and Queen of Hearts make everyone attend court over the
case of the missing tarts. Alice thought everything seemed very official with the jury box that held all
of the jurors with their slates, and the king as the judge with his white wig on. Eventually, Alice
discovers that the jury is writing the words Stupid things on their slates, and one of them does not
even spell the word stupid correctly (130 Carroll). This continues on with the witnesses, but between
every break the king calls for the verdict of the jury. This does relate to the time period because it was
rumored that when it came to the court system in the 1800 s, the witnesses never really mattered to the
judge. This rumor was reflected onto the King of Heart s character. Throughout the court case, Alice
begins to openly announce her thoughts to the courtroom. She criticizes the queen s decision to make
the sentence before the verdict, Stuff and nonsense! The idea of having the sentence first! (146). It is
thought that the Queen of Hearts actually symbolizes a real queen of England. Queen Margaret of
Anjou ruled from 1445 to 1461, and then again from 1470 to 1471. She was married to King Henry
VII and she had a son named Edward. She fought for the house of Lancaster which has a red rose for
its family name (Margaret). This does connect to the Queen of Hearts when her servants had to paint
the roses red. Why, the fact is, you see, Miss, this here ought to have been a red rose tree, and we put a
white one in by mistake; and, it the Queen was to find it out, we should all have our heads cut off, you
know. (90). The white roses were the symbol for the house of York, these two houses fought for the
right to the English throne in the War of the Roses. In the end of Queen Margaret s reign, her son was
killed by getting his head cut off, which is

A Sexual Reproduction
ASEXUAL REPRODUCTION
Asexual reproduction is a mode of reproduction by which offspring arise from a single parent, and
inherit the genes of that parent only; it is reproduction which does not involve meiosis, ploidy
reduction, or fertilization. The offspring will be exact genetic copies of the parent. A more stringent
definition is agamogenesis which is reproduction without the fusion of gametes. Asexual reproduction
is the primary form of reproduction for single celled organisms such as the archaea,bacteria, and
protists. Many plants and fungi reproduce asexually as well.
While all prokaryotes reproduce asexually (without the formation and fusion of gametes), mechanisms
for lateral gene transfer such as conjugation, transformation and ... Show more content on
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Plants that reproduce vegetatively may form a clonal colony, where all the individuals are clones, and
the clones may cover a large area.
SPORE FORMATION
Many multicellular organisms form spores during their biological life cycle in a process called
sporogenesis. Exceptions are animals and some protists, who undergo gametic meiosisimmediately
followed by fertilization. Plants and many algae on the other hand undergo sporic meiosis where
meiosis leads to the formation of haploid spores rather than gametes.
FRAGMENTATION
Fragmentation is a form of asexual reproduction where a new organism grows from a fragment of the
parent. Each fragment develops into a mature, fully grown individual. Fragmentation is seen in many
organisms such as animals (some annelid worms, turbellarians and sea stars), fungi, and plants. Some
plants have specialized structures for reproduction via fragmentation, such asgemmae in liverworts.
AGAMOGENESIS
Agamogenesis is any form of reproduction that does not involve a male gamete. Examples are
parthenogenesis and apomixis. Parthenogenesis is a form of agamogenesis in which an unfertilized
egg develops into a new individual. Parthenogenesis occurs naturally in many plants, invertebrates
(e.g. water fleas, rotifers, aphids, stick insects, some ants, bees and parasitic wasps), and vertebrates
(e.g. some reptiles, amphibians, fish, very rarely birds).
REGENERATION
In biology, regeneration is the process of renewal,

Greek City States Vs. Modern Greece
Greek city states are perfect examples of historian Peter Stearn s definition of classical civilizations.
At the height of its power between the 5th and 4th centuries, Greece s land included Asia Minor (in
modern Turkey), southern Italy, the island of Sicily, and the Greek islands. (Hornblower) Most of
these territories were independently governed and had strong political systems primarily democracy
which was born in Athens and became the basis for modern democratic governments in the United
States, France and other nations. Many Greek city states also developed core traditions in the arts and
sciences that endure today. All these factors distinguished Greek city states from river valley
civilizations as Stearns states, but like every society in history, each city state had its strengths and
weaknesses.
For example, there was a wide range of military power because Greek city states held different views
on its importance. During ancient times, Sparta built one of the strongest armies in classical Greece.
At the age of seven, all boys were moved from their homes to government barracks where they were
trained to be soldiers for 23 years. After that, they were expected to serve in the army for 30 years
until they retired at age 60. Sparta had an insatiable appetite for battle and aggressively went after the
territories of other city states, especially the land of its arch rival Athens.
Like Sparta, Athens was one of the largest and most formidable city states, but military

Taking a Look at the Manhattan Project
Although the Manhattan project was a bomb it was the psychological effects of the two bomb
droppings that did more damage than the actual destruction caused. The projected was started through
United States concern that the Germans were developing a similar weapon. It was kept a well guarded
secret and when it was used for the first time on a city caused a horrible shock. The decision to use the
bomb was not made lightly and had many different reasons behind it. It was made especially hard after
seeing the actual destruction it could cause because unveiling the technology would lead to others
wanting to replicate it. In the end though it was used on Japan and though it caused less damage than
previous air raids it lead to their surrender. While nuclear fission was believed to be possible in
Germany since 1938 it was not put into actionin the United States until 1943. That year Allied
scientists created a plan to use the fission to build an atomic bomb before the Germans could. In early
1939 word spread like wildfire that Germany had learned hot to split an atom. The fears this struck in
the scientific community encouraged scientist, like Albert Einstein, who fled Nazi persecution, and
Enrico Fermi, who escaped Fascist Italy, to approach the President. They wanted to express the
dangers of the technology and to urge him to start an atomic research program in the United States.
Fermi decided to travel to Washington only to be faced with the fact that no one else felt the

The Midwife s Tale By Laurel Thatcher Ulrich
This generation of women, may it be young or old, are fortunate to live in a country where you can be
anything, do anything, and say anything that men can. Although in theory the playing fields are still
not completely even, we as a nation have made some substantial progress in women s rights. Just a
few hundred years ago, women livered mundane lives and rarely got to speak up for themselves. In the
book, The Midwife s Tale by Laurel Thatcher Ulrich, it follows the life of Martha Ballard through the
use of her own diary. Martha Ballard captures the lives of common women in the Early Republic Era
by providing an authentic record of the role women played in their communities throughout the
developmental years of the United States. Some back ... Show more content on Helpwriting.net ...
This is what makes Mrs. Ballard s diary so important. Her journal demonstrates how she chose an
occupation that gives her complete authority over her own actions and career choices, which was rare
in the Early Republic Era. Her being a midwife let her dictate the jobs that she did and did not accept.
Martha gets the honor of showing the world that women of her time did all they could to be as
independent as possible. In The Midwife s Tale, Laurel Ulrich explains, She gardened, sewed, cared
for her grandchildren, nursed the sick, laid out the dead, and delivered babies (276). She was a woman
of many talents. Martha lived by a value that she expects the same respect in return and undertakes
full authority over the responsibilities she considers to be her own.
An important quote that gives the newer generation an idea of the common women at this time is from
the March 1804 chapter. Historian Laurel Ulrich quotes, The mixing of governours in a household, or
subordinating or uniting of two masters, or two dames under one roof, doth fall out most times, to be a
matter of much unquietness to all parties (281). This is a quote from 1624, an early English essay on
marriage. This quote is in regards to the clear annoyance Martha journaled about in her March entries
regarding her husband. Martha feels she alone should get the right to manage all the female workers
who enter their

Negotiations In 12 Angry Men
Mahmoud Abdallah Instructor: Dr. Wael Zaraket
Negotiation Conflict resolution April 21, 2017
12 Angry Men illustrates how successful negotiations necessitates careful observation and analysis of
different, conflicting arguments presented by the various parties involved, such that emotions and
positions are effectively separated from the more deeply entrenched and often concealed interests.
These actions were performed by Juror 8, who proceeded to question the other jurors motivations
behind their assertion of a guilty verdict (position). This movie illustrates how specific positions were
of little significance in determining the ... Show more content on Helpwriting.net ...
Eventually, the audience and jurors do not know if the boy truly committed the murder or not (only
reasonable doubt was established, based on the testimonial evidence presented); the boy s true
innocence or guilt had no bearing on the jury s final agreement; the agreement was derived by
systemically questioning and addressing the assumptions and motivations (interests) backing the
jurors decisions.
While all twelve jurors essentially desired justice to be served (according to their personal definitions
and interpretations) in the case, which is all parties fundamental interest, Juror 8 adopted a different
position from the other jurors, due to his compassion and desire to see the teenager get a fairly
deliberated verdict. Juror 3 opted for guilty , making the mistake of attempting to solve the wrong
problem by having a

Examples Of Identity Formation In The Outsiders
Identity formation and point of view is affected by stereotypes and life circumstances. In S.E. Hinton s
The Outsiders circumstances and stereotypes makes the characters struggle with who they are. The
Outsiders is told from the point of view of Ponyboy. Ponyboy is golden and unconcerned with
stereotypes and through him we observed how the other characters are affected by those stereotypes.
The characters identity formations are delayed by stereotypes; greasers are seen as dirty, low life
hoodlums, and Socs are seen as rich kids with all the brakes. The life experiences of the characters are
explored throughout The Outsiders.
Dally and Johnny are two characters that display how their experiences and greaser stereotypes shape
them throughout the novel. Johnny is unable to form his identity because of the difficulties in his
relationships with his family and the Greasers. If you can picture a little dark puppy that has been
kicked too many times and is lost in a crowd of strangers you ll have Johnny. This quote demonstrates
that he s weak and broken as a result of being beaten, ignored, yelled at, and insulted at home. If
Johnny didn t get neglected, he may have been a completely different person. If it hadn t been for the
gang, Johnny would never have known what love and affection are. page 12. And here we see he
would have been completely shattered if it wasn t for the gang who treats him as ... Show more
Hinton s The Outsiders explores identity from the point of view of Ponyboy. Through Ponyboy, we
see how the greasers become who they are and struggle with their identities as young men. Our
personalities are influenced by many things. Stereotypes and circumstances are factors that can change
and shape people. Stereotypes can be broken down to find your real identity. Our circumstances and
experiences shape who we are and we see through Ponyboy that it s a constant give and take as he s
affected by his environment and in turn affects the environment around

Premature Infant Stimulation
It is known that then stimulation of infants during the first few months is important for proper
development to take place. Following, we will review the importance of both a stimulating
environment and the need for physical stimulation provided by caregivers.
A lot of emphasis has been placed on physical, mother infant, interaction, but studies have shown that
inanimate stimulation is as important as social stimulation. Yarrow, Rubenstein, Pedersen, and
Jankowski (1972) examined the importance of stimulation from caregiver interaction and the natural
environment. The emphasis of their work was to study the impact of disadvantaged environments on
infant development. What their work did show was that the environment of the infant was just ...
Show more content on Helpwriting.net ...
When we look at infants in orphanages in Romania, we find children that are deprived of the complex
physical contact normally received by other children that have a dedicated caregiver. These children
show serious intellectual deficits, and although they show improvement later, they never catch up to
their peers who were raised in more traditional environments (Berk, 2014). When we look at
premature infants, who spend a large amount of their time in incubators, we find that they show
slower gains in mass and motor function then their peers. Now, when premature infants are given 15
minutes of mechanosensory stimulation, three times a day for ten days, they show an increase in
weight along with more time awake and active. They also would show more improvement than their
unstimulated peers based on the Brazelton Neonatal Behavioral Assessment Scale (Ardiel Rankin,
2010)
The effects of stimulation on infant development cannot be understated. The more research that has
gone into the importance of this the more emphasis is placed on attempting to correct sensory
deprivation. In hospital NICUs we see more interaction with children that are born premature. We are
also seeing a greater emphasis on placing orphaned children into homes where they can benefit from
direct caregiver contact and have a more stimulating environment to explore. Now, more than in the
past, we see the need

Vegan Protein Powder
As a vegan, I had my fair share of gritty, bad tasting, plant based protein powders that cause bloating
or have mediocre ingredients. That s why I regularly check for new vegan protein powders that are
wholesome and undenatured and without cheap sugars and artificial sweeteners. Fortunately, I was
lucky and could receive one free full size bag of Healthy LifeStyle Vanilla Honey Vegan Meal
Replacement Shake / Smoothie Mix Protein in exchange for leaving my experience with and
assessment of this vegan protein/meal replacement in an honest review. This vegan protein powder
comes packaged in an easy to store, resealable zip lock bag and includes a measuring scoop which I
didn t see at first. It was buried deep in the bag and I had to dig for it with ... Show more content on
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All ingredients are natural, wholesome, and fully suitable for vegans. This protein powder features a
blend of organic proteins from sprouted rice, sprouted yellow pea and hemp. The keyword here is
sprouted: sprouting any grains, legumes or seeds neutralizes phytic acid and enzyme inhibitors.
Neutralizing enzyme inhibitors is important as they do not only inhibit enzymes in the actual seed but
can also inhibit your own enzymes once ingested. Hemp seeds in this powder are not sprouted as they
do not contain any harmful phytic acid and are easily digestible. Next on the list are the Superfoods
Blend w/ fiber and the Vegan Multi Vitamin/Mineral w/ Greens Superfoods Blend , I love those blends
very much as they contain so many power foods, antioxidants, vitamins, minerals and other nutrients
that make this protein powder a convenient, healthy meal replacement. Never did I feel bloated with
this very balanced protein/meal replacement powder. Its Digestive Enzymes Complex may help me
with my digestion. It is really gentle on my stomach and satisfies me very good as I have fewer urges
to grab a snack between

Love Machine Research Paper
Meta: Are you ready to feel the love? If so, SkillOnNet certainly has a treat in store, as Love Machine
serves up plenty or romance fuelled online slots fun!
//header//
Love Machine (SkillOnNet)
//copy//
It s quite likely that mentioning Love Machine would cause most of our readers to remember that
popular 70s song from The Miracles. Well this slot machine from SkillOnNet might not have much to
do with that song, but it s still got a similar theme of passionate love. To be frank from the start, Love
Machine isn t a slot machine that is going to get you all hot and bothered at the prospect of winning
big payouts, nor does it offer plenty of special symbols, bonus round, and gamble options. Its actually
rather basic and toned down, almost like an unplugged slot that offers easy play and even easier
enjoyment.
Say it with a Diamond
The symbols featured in Love Machine are ... Show more content on Helpwriting.net ...
Many newcomer players, in particular those with no prior knowledge of betting real cash with online
gambling and gambling portals, want to play at slots that are easy to use. They want to know they can
play a game, even if it means playing for smaller amounts of money. SkillOnNet have jumped on the
idea, as many slots in their catalogue are super simple and make betting a breeze. Love Machine is no
exception. The slot is hardly a mystery, as there s just 3 reels and 3 paylines.
To make the most out of the money you put into Love Machine, you ll want to land some good
combinations. Many online slots offer combinations made of three or more symbols, but Love
Machine brings the minimum down to 2 for some symbols; giving you even more chance of landing a
winning combination. There s a lot of love in the air. If you aren t feeling it, then spin the reels and
keep your fingers crossed, with a 600 coin base game jackpot riding on the line.
Feeling a Touch of

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