This document discusses applications of nanotechnology in dentistry. It describes how nanotechnology can be used to mimic natural enamel formation, replace bone, diagnose and treat oral cancer using targeted drug delivery, induce local anesthesia, reduce dentin hypersensitivity, use nanorobots for orthodontics, and prevent dental caries. While this technology offers promising applications, it is not completely safe and further research is needed to ensure safety. The future of nanotechnology in dentistry may include whole new teeth and restorations formed at the nanoscale level.

1. Nanotechnology in
Dentistry
Done By :
Omar Hassem ,Karim
Mohamed ,Mark Nabeel
,Mena George
Under supervision of:
A.Prof Samah Kamel

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3. What is Nanotechology ?
 It is the study and application of
extremely small things
 It involves the ability to see and to
control individual atoms and
molecules
Why NANO ?
Because nano particles are
governed by a different set
of physics that govern
ordinary objects, so they
can be used for a wide
variety of uses
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5. I. Enamel Formation :
◇ It is mimicking processes that occur in nature such as formation of
dental enamel
◇ If carious or erosive enamel defects enlarge, they cannot be
repaired by remineralization techniques
◇ There is a cooperation interaction between the amelogenin and
the HA crystals
◇ The interaction happens at critical points during the HA crystal-
growth. There is matching between organic and inorganic
nanophases that may resemble processes that occur in actual
enamel formation.
◇ Amelogenin is important in directing and ordering apatite crystal
growth.
◇ Various types of amelogenin renders it versatile during enamel
formation
◇ Ultimately, Proper use of materials deal with this technology is a
must

6. II. Bone Replacement :
How can nanotechnology replace it?
◇ Bone is a natural nanostructure
◇ Composed of organic compounds and reinforced with
inorganic ones.

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8. I. Diagnosis and treatment of
oral cancer :
Nanotechnology is probably the only method that can be
used for site-specific action without causing side effects
by killing the normal cells.
How can we diagnose oral cancer?
◇ Optical Nanobiosensor
◇ Cantilever Array Sensors
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So How can we treat oral cancer ?
 Drug Delivery Across The Blood-Brain Barrier:
 Nanovectors For Gene Therapy
 Nanomaterials For Brachytherapy

9. What happens to the gingiva of the patient when
nanorobots are used to induce anesthesia?
 The gingiva of the patient is instilled with a colloidal suspension
dental robots that respond to input supplied by the dentist.
 Nanorobots in contact with the surface of the crown or mucosa can
reach the pulp via the gingival sulcus, lamina propria, or dentinal
tubules
 Once in the pulp, they shut down all sensations
II. Local anesthesia :

10. III. Dentin Hypersensitivity :
◇ Reconstructive dental nanorobots are able to selectively
and precisely block dentinal tubules, offering a quick and
permanent cure. These nanorobots travel toward the dental
pulp via the dentinal tubules. Desensitizing toothpaste
containing 15% hydroxyapatite nanoparticles has been
found to be effective in reduction of dentin
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11. IV:- Orthodontic Nanorobots :
◇ Orthodontic nanorobots could directly
manipulate the periodontal tissues,
thereby allowing a painless and rapid
method for correcting malocclusion
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12. V. Preventing dental caries :
◇ The use of a toothpaste containing nanosized
calcium carbonate enabled remineralization of
early enamel lesions. the bacteriostatic effects
of silver, zinc oxide and gold nanoparticles on
Streptococcus mutans, which causes dental
caries, have an antimicrobial effect.
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14. Is this technology totally safe ??
UNFORTUNATELLY, NO

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17. Future of nanotechnology
in dentistry
◇ Vital fillings and restorations
◇ Orthodontic nanorobots
◇ Whole new tooth !!

18. Thanks!
Any questions?
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19. References
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