FDA has made several efforts to secure the pharmaceutical supply chain: 1. The Office of Compliance within CDER was reorganized to better address threats like counterfeiting, diversion, and intentional adulteration. A new Office of Drug Security, Integrity, and Recalls was created. 2. Preliminary analysis of FDA criminal case information from 2003-2008 found that the top five branded drugs targeted were Zyprexa, Viagra, Lipitor, Zoloft, and Risperdal, and that solid oral dosage forms were most at risk. 3. FDA is working on track and trace standards and held a public workshop on the topic in 2011. A track and trace system