1. Microbiology Chapter 1

2. Part I Introduction to Microbiology

4. Prokaryotic vs. Eukaryotic

6. (Top) Coccidioidomycosis Arthrospores (Bottom) Development of Arthrospores Into spherule in lung tissue Fungal Infection of the lung Schistosoma (worms) at two different stages of development – liver Disease and other symptoms Staphylococcus Aureus Gram positive bacteria Staph infections and MRSA Trypanosoma Eukaryotic pathogen African Sleeping Sickness Treponema pallidum Bacterial spirochete Causes syphilis Mycobacterium tuberculosis. Acid fast bacteria (shown in pink) like this causes TB and leprosy. Light blue is Staph epi, a common bacteria cocci which inhabits the Skin. Not a common pathogen Herpes Virus

7. Size Comparisons

8. What Do Microbes Do? Photosynthesis Decomposition Soil Fertility & Microbial Ecology Microbial Physiology & Fermentation of Cheese Wine Bread Genetics, Gene Regulation & Biotechnology Bioremediation Oil Eating Bacteria & Fungi Water Purification Infectious Disease & Immunology Ch 4, 7, & 26 Ch 8 & 27 Ch 9 & 10 Ch 27 Briefly Need an Environmental & Applied Micro Course Ch 14 – 16 & Ch 18 - 25

9. Part II Historical Figures in Microbiology

20. Koch’s Postulates Mouse dies with sores Take scraping and plate on agar A heterogeneous population of bacteria Grow – which one is the causative agent Isolate all different strains and types and inject into healthy mice and see which mice develop similar phenotype and symptoms Take a sample again from mice which died of same symptoms and isolate the causative agent again

21. Koch’s Postulates A sequence of experimental steps to relate a specific microbe to a specific disease

22. Koch’s Postulates Used to prove the specific causative agent of an infectious disease

26. Part III Introduction to Disease

30. All Diseases Old Standards Syphilis Measles Staph Infections Chicken Pox Emerging Avia Flu Antigenic shift event HIV in the 80’s West Nile in US in 2001 Continental travel Reemerging Tuberculosis - TB New drug resistant strains Immunocompromised patients

31. Top Causes of Death * Stands for lower respiratory disease Infectious Diseases are shown in red 1.19 x 10 6 10. Accidents 33,865 10.Septicemia 1.27 x 10 6 9. Malaria 40,970 9. Kidney problems 1.57 x 10 6 8. Tuberculosis 58,870 8. Alzheimer disease 1.80 x 10 6 7. Diarrheal disease 65,680 7. Flu & Pneumonia 2.75 x 10 6 6. Chronic LRD* 73,250 6. Diabetes 2.78 x 10 6 5. HIV/AIDS 106,740 5. Accidents 3.33 x 10 6 4. Cancer 124,800 4. Chronic LRD* 3.88 x 10 6 3. Res infection 162,670 3. Stroke 5.51 x 10 6 2. Stroke 557,270 2. Cancer 8.12 x 10 6 1. Heart Disease 696,950 1. Heart Disease Deaths Worldwide Deaths United States

32. Infectious Disease Statistics

33. Part IV Taxonomy & Biological Classification

36. Taxonomy

40. Whittaker’s System

43. Three Domain System