Medical Simulation 3.0: Improving Patient Safety
and Healthcare Delivery Transformation
Yue Dong, M.D.
Disclosures
• The views and opinions are expressed in
following presentations are presenters’ own,
not representative of Mayo Clinic, Society of
Simulation of Healthcare(SSH), Healthcare
Systems Modeling and Simulation Affinity
Group (HSMSAG)
• Faculty and organizing committee do not
endorse or recommend any specific products or
services mentioned on this presentation.
• Faculty and organizing committee do not have
any personal financial interest related to the
presentation.
©2011 MFMER | 3123886-3
Mayo Clinic Core Value:
Quality (Outcome + Safety + Service)
Value =
Cost per over time
Smoldt RK, Cortese DA. Pay-for-performance or pay for value? Mayo Clinic Proceedings 2007;82:210-3
“The needs of the patient come first.”
Surgical never events and contribution human factors
Mayo Clinic
roughly 1 in every
22,000 procedures
National Practitioner
Data Bank
1 in every 12,000
procedure
Thiels CA, et al. Surgery 2015 May 29 http://www.ncbi.nlm.nih.gov/pubmed/26032826
Minnesota Adverse Events 2015
©2011 MFMER | 3123886-6
Rates of All Harms, Preventable Harms, and High-Severity Harms per 1000 Patient-Days,
Identified by Internal and External Reviewers, According to Year
Landrigan CP et al. N Engl J Med 2010;363:2124-2134
Rates of All Harms, Preventable Harms, and High-Severity Harms per
1000 Patient-Days, Identified by Internal and External Reviewers,
According to Year
Landrigan CP et al. N Engl J Med 2010;363:2124-2134
Healthcare systems safety
• 400,000 Americans
die each year as a
result of medical
errors. (3rd after heart
disease and cancer)
• $765 billon (35%) US
healthcare cost is
wasted each year
• US annual healthcare
cost more than $ 3
trillion (16% GDP)
James JT. Journal of Patient Safety 2013;9:122-128; CDC.gov;
http://resources.iom.edu/widgets/vsrt/healthcare-waste.html
ICU as Systems of Systems
Adopted from: Network medicine--from obesity to the "disease". Barabási AL., N Engl J Med. 2007 Jul 26;357(4):404-7.
SHOCK
DIC AKI
ALI
Physician RT
Pharmacist
Nurse
Time 
Baseline
PatientOutcome,
ProviderSatisfactions
Learning Healthcare Systems
• Significant changes in the health
care delivery system, changes
largely concerned with organization
• quality improvement
• operational efficiency
• error reduction and patient safety
IOM. The Learning Healthcare System: Workshop Summary. Washington, DC: The National Academies Press; 2007.
“Blue Highways” on the NIH Roadmap
Practice-based
research
Phase 3 and 4 clinical
trials
Observational studies
Survey research
Basic science
research
Preclinical studies
Animal research
Human clinical
research
Controlled
observational studies
Phase 3 clinical trials
T1
Case series
Phase 1 and 2
clinical trials
Clinical practice
Delivery of recommended
care to right pt at right time
Identification of new clinical
questions and gaps in care
T2
Translation
to humans
T2
Guideline
development
Meta-analyses
Systematic
reviews
Translation
to patients
T3
Dissemination
research
Implementation
research
Translation
to practice
Westfall JM et al: JAMA 297:403, 2007
Bench Bedside Practice
The Science of Healthcare Delivery
• Understanding disease biology
• Finding effective therapies
•Therapies delivered effectively
2011, Health IT and Patient Safety: Building Safer Systems for Better
Care, Committee on Patient Safety and Health Information Technology; Institute of
Medicine
What is simulation?
• Simulation is the imitation or
representation of one act or system by
another.
• Healthcare simulations have four main
purposes – education, assessment,
research, and health systems
integration to facilitate patient safety…
©2011 MFMER | 3123886-16
Society for Simulation in Healthcare
SSH Membership Continuing Growth
17
180
539
1205
1520
1702
1850
2438
2925 2918
0
500
1000
1500
2000
2500
3000
3500
2005 2006 2007 2008 2009 2010 2011 2012 2013
History of medical simulation
1026
宋代针灸铜人
1969
SimOne
Dr. Abrahamson
Simulation 1.0
Education Assessment
Systems
Integration
Research
Simulation
Mayo Clinic Multidisciplinary Simulation Center
Ultrasound guided central line insertion
Precourse- literature review
Precourse exam (Online)
Cadaver lab (Procedural Skills Lab)
(1 hour)
Ultrasound hands-on station
(1 hour)
Gown/Gloving/Universal Precautions
(1 hour)
Certification Station
(following with feed back)
Briefing
Experience
Debriefing
Learninggoaldriven
Central Line Workshop
Courtesy of William Dunn, MD
Clinical competence
Metricassessment
Time
Traditional training
Safety standard
Simulation-based training
Simulation-based objective assessment Discern Clinical Proficiency in Central Line Placement, Dong, et. al,
CHEST 2010
©2011 MFMER | 3123886-24
©2011 MFMER | slide-25
WHO Global Priorities for Patient Safety Research
Bates DW, et al. Global priorities for patient safety research. BMJ 2009;338:b1775
ED Trauma Team Training
©2011 MFMER | 3123886-26
Learning Objective
Faculty Development
Curriculum
Facility and
Technology
Assessment
Debriefing
Simulation based education
Learners
Key questions for SBT?
• Does the simulation-based education work
• How does simulation compare with other
instructional approaches?
• Why are some simulation interventions better
than others (and how can we improve them
all)?
• Is simulation-based education worth its costs?
David Cook, The literature on healthcare simulation education: What does It show ?
http://webmm.ahrq.gov/perspective.aspx?perspectiveID=138#ref8
ROI of Simulation based training
• Approximately 9.95 CRBSIs were
prevented among MICU patients with
CVCs/year
• Cost of CRBSI were $82,000 in 2008
dollars and 14 additional hospital days
(including 12 MICU days).
• Cost of the simulation-based education
$112,000.
• 7 to 1 rate of ROI
Shannon DW. How a Captive Insurer Uses Data and Incentives to Advance Patient Safety. PSQH. Nov/ Dec 2009.
Simulation 1.0
©2011 MFMER | 3123886-32
Education Assessment
Systems
Integration
Research
Simulation
©2011 MFMER | 3123886-33
Five steps to develop checklists for evaluating clinical performance: An integrative approach。 Schmutz J, Eppich WJ,
Hoffmann F, Heimberg E, Manser T. Academic Medicine. 2014 Jan;89(7):996-1005
Central Line Procedure Checklist
Simulation-based objective assessment Discern Clinical Proficiency in Central Line Placement, Dong, et. al, CHEST 2010
©2011 MFMER | slide-35
Simulation-based objective assessment Discern Clinical Proficiency in Central Line Placement, Dong, et. al, CHEST 2010
Short-term and Long-term Impact of the Central Line Workshop on Resident Clinical Performance During Simulated
Central Line Placement。 Laack, Dong, et al. Simulation in Healthcare 9 (4), 228-233
“Medicine used to be simple, ineffective and relatively
safe. Now it is complex, effective and potentially
dangerous” Sir Cyril Chantler
Information overload
2012, IOM, Discussion Paper1: The Clinical Trials Enterprise in the United States: A Call for Disruptive Innovation
The Complexities of Physician Supply and Demand: Projections Through 2025. 2008 AAMC http://www.aamc.org/workforce
“ Simply educating and
training more physicians
will not be enough to
address these
shortages. Complex
changes such as
improving efficiency,
reconfiguring the way
some services are
delivered and making
better use of our
physicians will also be
needed.”
Simulation 2.0
©2011 MFMER | 3123886-41
Education Assessment
Systems
Integration
Research
Simulation
Human Factor Research
• Using simulation as a tool to study human
performance variation under different “stress
conditions” (fatigue, cognition, workload,
etc.)
• conduct usability testing of devices
instrument and processes
The effect of drug concentration expression on
epinephrine dosing errors: a randomized trial
Wheeler DW, Carter JJ, Murray LJ, Degnan BA, Dunling CP, Salvador R, et al.. Ann Intern Med 2008;148:11-4.
(1 mg in 1 mL) (1 mL of a 1:1000 solution)
Arriaga AF, Bader AM, Wong JM, et al. Simulation-based trial of surgical-crisis checklists. N Engl J Med 2013;368:246-253
Ahmed, et al. Critical Care Medicine, 39(7) 1626-1634
The effect of two different electronic health record user interfaces on
intensive care provider task load, errors of cognition, and performance
Simulation 3.0
©2011 MFMER | 3123886-46
Education Assessment
Systems
Integration
Research
Simulation
Dr. Lucian Leape Dr. Donald M. Berwick
Transforming healthcare: a safety imperative
L Leape, D Berwick, C Clancy, et al. Qual Saf Health Care 2009; 18:424-428
A technical systems grow in
complexity and
connectedness, inevitably
will lead to accidents with
catastrophic potential
• the degree of system
complexity
• tight coupling of processes,
• and the inability of a single
individual or small group of
individuals to manage all
the potential interactions
• Stochastic escalation
©2011 MFMER | 3123886-49
Perrow, C. Living with high-risk technologies. Princeton University Press:
John Wiley and Sons Ltd; New Jersey: 1999.
What is system integration?
Caffezo, et al rom discovery to design, Human factor in healthcare, 2012
Modeling Complexity (Rouse, 2007)
“ Starting with this model of the enterprise, the overarching strategy should focus on increasing complexity where
it can be managed best and decreasing complexity for end users.”
Adjust structure and process to eliminate or minimize
risks of health care-associated injury, before they have
an adverse event-impact on the outcomes of care
Donabedian. Evaluating of Medical Care. The Milbank Memorial Fund Quarterly, Vol. 44, No. 3, Pt. 2, 1966 (pp. 166–203)
Systems Engineering Initiative for Patient Safety (SEIPS) Work system design for patient safety: the SEIPS model.Carayon P, et al . Qual Saf Health Care. 2006 Dec;15 Suppl
1:i50-8. Review.
Simulation, modeling and Analysis, Law and Kelton, 2000
Robert Pool, Science, Vol. 256, No. 5053 (Apr. 3, 1992)
“ Computation has become a ‘third branch’ of
science, alongside theory and experiment”
McDonnell , G. (July, 2007).Workshop on Multiscale Modeling using AnyLogic 6 with Health Examples at International System Dynamics
Society Conference. Boston, MA
Simulation Application in Healthcare
Operation Research using DES
(Discrete Event Simulation)
1. Formulate the research question
2. Define the operational process (workflow)
3. Collect date to fit distribution
4. Construct and validate the model
5. Run experiment
©2011 MFMER | 3123886-60
Crit Care Med 2007 Vol. 35, No. 11
Critical Importance of Timing
Spain Study
Ferrer R, et al. Improvement in process of care and outcome after a multicenter severe sepsis educational program in Spain. JAMA.
2008;299(19):2294-2303.
Research Methodology
Baseline Process
Identify Causes of
Delay
Process Modeling
Suggestions for
Improvement
Measure ImpactSensitivity Analysis
Statistical Analysis
Root Cause Analysis &
FMEA
Discrete-Event
Simulation
ANOVA
Design of Experiment
User Requirement
and Scope
Workflow analysis by providers
Data Collection
• Time frame
• Dec 2007 to June 2009
• Sample size:
• 600 sepsis patients
• Source of data
• Sepsis QI Project (Courtesy of Dr. Afessa)
• EMR: ICU Datamart
• Direct observations: CVC, fluid infusion, etc.
• Expert opinions: MD, RN, RT, Pharmacist, et al
• Administration database
• Obstacles with data
• Uncompleted dataset
• Care process variation
Fellow ResidentConsultant PharmacistBedside RN
Sepsis
Recongnition
Antibiotics/
Source Control
Fluid
Resuscitation
Central Venous
Catheterization
Vesopressor
Administration
Inotrope
Administration
Transfusion
Patient
SepsisResuscitationGoalReached
Simulation Modeling of Healthcare Delivery During Sepsis Resuscitation
Dong Y, et al. Optimization of healthcare delivery during sepsis resuscitation by simulation and modeling. Simulation in Healthcare 2010;5:423.
Accelerated
T&X
CVC Efficiency
ScVO2
Monitors
No CXR DelayEarly Recognition
ResuscitationRecognition
Sepsis Care Optimization by Discrete Event Simulation (S-CODES)
Model Validation
Empirical
Data
Model
Data
%
Variance
Duration (months) 18 18 0%
Total Sepsis
Patients
597 600 0.5%
Average number
of patients/day
2.4 2.7 -1.3 %
Average Cycle
Time (min)
382 418 9.4 %
Sepsis Resuscitation Time Reduction by Different Options
Clinical
Data
Sepsis Resusiation Time Reducation by Different Options
29.16
26.81
7.81
137.92
16.11
55.94
0.00
30.00
60.00
90.00
120.00
150.00
Opt 1 - Early Recog Opt 2 - Quick CVC Opt 3 - No X-Ray Opt 4 - Pre
Type/Cross
Opt 5 - ScVO2
Monitors
Opt 6 - All
Time(min)
DES study in clinical practices
• Analyze & Visualize patient
flow (Batarseh 2014)
• Optimize unit bed capacity
(Zhu 2012)
• Forecast near-future
operation status (Hoot
2009)
• Study interaction between
providers (Lim 2013)
• Evaluate ED/EMS
interaction (Stahl 2003)
• Decrease inpatient
boarding (Levin 2008)
©2011 MFMER | 3123886-71
Recent Major Reports
• Executive Office of the President President’s Council of Advisors on Science and Technology: Report To The President Better Health Care And Lower Costs: Accelerating
Improvement Through Systems Engineering (May 2014)
• National Science Foundation: Operations Research - A Catalyst for Engineering Grand Challenges (May 2014)
• The ASQ Healthcare Division Marshall Plan: "Put Me In The Game, Coach! ” (The Quality Management Forum, Winter 2014)
Simulation to improve quality and safety
Constructive
Virtual
Live
Training
Assessment
Research and
Integration
Patient
Healthcare Providers
Healthcare Systems
©2011 MFMER | 3123886-76
Learning from others
Summary
• Quality and patient safety are the
driver for value based healthcare
delivery
• Use more simulation to
• Improve provider and team skills
• Improve systems performance
From Mayo Clinic Center for Innovation
Healthcare Systems Modeling & Simulation Affinity
Group
goo.gl/PRIkog
goo.gl/0r5mOs
http://www.ssih.org/Interest-
Groups/Healthcare-Systems-Modeling-
Simulation
goo.gl/7QuuQd

Medical Simulation 3.0

  • 1.
    Medical Simulation 3.0:Improving Patient Safety and Healthcare Delivery Transformation Yue Dong, M.D.
  • 2.
    Disclosures • The viewsand opinions are expressed in following presentations are presenters’ own, not representative of Mayo Clinic, Society of Simulation of Healthcare(SSH), Healthcare Systems Modeling and Simulation Affinity Group (HSMSAG) • Faculty and organizing committee do not endorse or recommend any specific products or services mentioned on this presentation. • Faculty and organizing committee do not have any personal financial interest related to the presentation.
  • 3.
    ©2011 MFMER |3123886-3
  • 4.
    Mayo Clinic CoreValue: Quality (Outcome + Safety + Service) Value = Cost per over time Smoldt RK, Cortese DA. Pay-for-performance or pay for value? Mayo Clinic Proceedings 2007;82:210-3 “The needs of the patient come first.”
  • 5.
    Surgical never eventsand contribution human factors Mayo Clinic roughly 1 in every 22,000 procedures National Practitioner Data Bank 1 in every 12,000 procedure Thiels CA, et al. Surgery 2015 May 29 http://www.ncbi.nlm.nih.gov/pubmed/26032826
  • 6.
    Minnesota Adverse Events2015 ©2011 MFMER | 3123886-6
  • 7.
    Rates of AllHarms, Preventable Harms, and High-Severity Harms per 1000 Patient-Days, Identified by Internal and External Reviewers, According to Year Landrigan CP et al. N Engl J Med 2010;363:2124-2134 Rates of All Harms, Preventable Harms, and High-Severity Harms per 1000 Patient-Days, Identified by Internal and External Reviewers, According to Year Landrigan CP et al. N Engl J Med 2010;363:2124-2134
  • 8.
    Healthcare systems safety •400,000 Americans die each year as a result of medical errors. (3rd after heart disease and cancer) • $765 billon (35%) US healthcare cost is wasted each year • US annual healthcare cost more than $ 3 trillion (16% GDP) James JT. Journal of Patient Safety 2013;9:122-128; CDC.gov; http://resources.iom.edu/widgets/vsrt/healthcare-waste.html
  • 10.
    ICU as Systemsof Systems Adopted from: Network medicine--from obesity to the "disease". Barabási AL., N Engl J Med. 2007 Jul 26;357(4):404-7. SHOCK DIC AKI ALI Physician RT Pharmacist Nurse Time  Baseline PatientOutcome, ProviderSatisfactions
  • 11.
    Learning Healthcare Systems •Significant changes in the health care delivery system, changes largely concerned with organization • quality improvement • operational efficiency • error reduction and patient safety IOM. The Learning Healthcare System: Workshop Summary. Washington, DC: The National Academies Press; 2007.
  • 12.
    “Blue Highways” onthe NIH Roadmap Practice-based research Phase 3 and 4 clinical trials Observational studies Survey research Basic science research Preclinical studies Animal research Human clinical research Controlled observational studies Phase 3 clinical trials T1 Case series Phase 1 and 2 clinical trials Clinical practice Delivery of recommended care to right pt at right time Identification of new clinical questions and gaps in care T2 Translation to humans T2 Guideline development Meta-analyses Systematic reviews Translation to patients T3 Dissemination research Implementation research Translation to practice Westfall JM et al: JAMA 297:403, 2007 Bench Bedside Practice
  • 13.
    The Science ofHealthcare Delivery • Understanding disease biology • Finding effective therapies •Therapies delivered effectively
  • 14.
    2011, Health ITand Patient Safety: Building Safer Systems for Better Care, Committee on Patient Safety and Health Information Technology; Institute of Medicine
  • 15.
    What is simulation? •Simulation is the imitation or representation of one act or system by another. • Healthcare simulations have four main purposes – education, assessment, research, and health systems integration to facilitate patient safety…
  • 16.
    ©2011 MFMER |3123886-16 Society for Simulation in Healthcare
  • 17.
    SSH Membership ContinuingGrowth 17 180 539 1205 1520 1702 1850 2438 2925 2918 0 500 1000 1500 2000 2500 3000 3500 2005 2006 2007 2008 2009 2010 2011 2012 2013
  • 18.
    History of medicalsimulation 1026 宋代针灸铜人 1969 SimOne Dr. Abrahamson
  • 19.
  • 20.
  • 21.
  • 22.
    Precourse- literature review Precourseexam (Online) Cadaver lab (Procedural Skills Lab) (1 hour) Ultrasound hands-on station (1 hour) Gown/Gloving/Universal Precautions (1 hour) Certification Station (following with feed back) Briefing Experience Debriefing Learninggoaldriven Central Line Workshop Courtesy of William Dunn, MD
  • 23.
    Clinical competence Metricassessment Time Traditional training Safetystandard Simulation-based training Simulation-based objective assessment Discern Clinical Proficiency in Central Line Placement, Dong, et. al, CHEST 2010
  • 24.
    ©2011 MFMER |3123886-24
  • 25.
    ©2011 MFMER |slide-25 WHO Global Priorities for Patient Safety Research Bates DW, et al. Global priorities for patient safety research. BMJ 2009;338:b1775
  • 26.
    ED Trauma TeamTraining ©2011 MFMER | 3123886-26
  • 27.
    Learning Objective Faculty Development Curriculum Facilityand Technology Assessment Debriefing Simulation based education Learners
  • 28.
    Key questions forSBT? • Does the simulation-based education work • How does simulation compare with other instructional approaches? • Why are some simulation interventions better than others (and how can we improve them all)? • Is simulation-based education worth its costs? David Cook, The literature on healthcare simulation education: What does It show ? http://webmm.ahrq.gov/perspective.aspx?perspectiveID=138#ref8
  • 30.
    ROI of Simulationbased training • Approximately 9.95 CRBSIs were prevented among MICU patients with CVCs/year • Cost of CRBSI were $82,000 in 2008 dollars and 14 additional hospital days (including 12 MICU days). • Cost of the simulation-based education $112,000. • 7 to 1 rate of ROI
  • 31.
    Shannon DW. Howa Captive Insurer Uses Data and Incentives to Advance Patient Safety. PSQH. Nov/ Dec 2009.
  • 32.
    Simulation 1.0 ©2011 MFMER| 3123886-32 Education Assessment Systems Integration Research Simulation
  • 33.
    ©2011 MFMER |3123886-33 Five steps to develop checklists for evaluating clinical performance: An integrative approach。 Schmutz J, Eppich WJ, Hoffmann F, Heimberg E, Manser T. Academic Medicine. 2014 Jan;89(7):996-1005
  • 34.
    Central Line ProcedureChecklist Simulation-based objective assessment Discern Clinical Proficiency in Central Line Placement, Dong, et. al, CHEST 2010
  • 35.
    ©2011 MFMER |slide-35 Simulation-based objective assessment Discern Clinical Proficiency in Central Line Placement, Dong, et. al, CHEST 2010
  • 36.
    Short-term and Long-termImpact of the Central Line Workshop on Resident Clinical Performance During Simulated Central Line Placement。 Laack, Dong, et al. Simulation in Healthcare 9 (4), 228-233
  • 38.
    “Medicine used tobe simple, ineffective and relatively safe. Now it is complex, effective and potentially dangerous” Sir Cyril Chantler
  • 39.
    Information overload 2012, IOM,Discussion Paper1: The Clinical Trials Enterprise in the United States: A Call for Disruptive Innovation
  • 40.
    The Complexities ofPhysician Supply and Demand: Projections Through 2025. 2008 AAMC http://www.aamc.org/workforce “ Simply educating and training more physicians will not be enough to address these shortages. Complex changes such as improving efficiency, reconfiguring the way some services are delivered and making better use of our physicians will also be needed.”
  • 41.
    Simulation 2.0 ©2011 MFMER| 3123886-41 Education Assessment Systems Integration Research Simulation
  • 42.
    Human Factor Research •Using simulation as a tool to study human performance variation under different “stress conditions” (fatigue, cognition, workload, etc.) • conduct usability testing of devices instrument and processes
  • 43.
    The effect ofdrug concentration expression on epinephrine dosing errors: a randomized trial Wheeler DW, Carter JJ, Murray LJ, Degnan BA, Dunling CP, Salvador R, et al.. Ann Intern Med 2008;148:11-4. (1 mg in 1 mL) (1 mL of a 1:1000 solution)
  • 44.
    Arriaga AF, BaderAM, Wong JM, et al. Simulation-based trial of surgical-crisis checklists. N Engl J Med 2013;368:246-253
  • 45.
    Ahmed, et al.Critical Care Medicine, 39(7) 1626-1634 The effect of two different electronic health record user interfaces on intensive care provider task load, errors of cognition, and performance
  • 46.
    Simulation 3.0 ©2011 MFMER| 3123886-46 Education Assessment Systems Integration Research Simulation
  • 47.
    Dr. Lucian LeapeDr. Donald M. Berwick Transforming healthcare: a safety imperative L Leape, D Berwick, C Clancy, et al. Qual Saf Health Care 2009; 18:424-428
  • 49.
    A technical systemsgrow in complexity and connectedness, inevitably will lead to accidents with catastrophic potential • the degree of system complexity • tight coupling of processes, • and the inability of a single individual or small group of individuals to manage all the potential interactions • Stochastic escalation ©2011 MFMER | 3123886-49 Perrow, C. Living with high-risk technologies. Princeton University Press: John Wiley and Sons Ltd; New Jersey: 1999.
  • 50.
    What is systemintegration?
  • 51.
    Caffezo, et alrom discovery to design, Human factor in healthcare, 2012
  • 53.
    Modeling Complexity (Rouse,2007) “ Starting with this model of the enterprise, the overarching strategy should focus on increasing complexity where it can be managed best and decreasing complexity for end users.”
  • 54.
    Adjust structure andprocess to eliminate or minimize risks of health care-associated injury, before they have an adverse event-impact on the outcomes of care Donabedian. Evaluating of Medical Care. The Milbank Memorial Fund Quarterly, Vol. 44, No. 3, Pt. 2, 1966 (pp. 166–203)
  • 55.
    Systems Engineering Initiativefor Patient Safety (SEIPS) Work system design for patient safety: the SEIPS model.Carayon P, et al . Qual Saf Health Care. 2006 Dec;15 Suppl 1:i50-8. Review.
  • 56.
    Simulation, modeling andAnalysis, Law and Kelton, 2000
  • 57.
    Robert Pool, Science,Vol. 256, No. 5053 (Apr. 3, 1992) “ Computation has become a ‘third branch’ of science, alongside theory and experiment”
  • 59.
    McDonnell , G.(July, 2007).Workshop on Multiscale Modeling using AnyLogic 6 with Health Examples at International System Dynamics Society Conference. Boston, MA Simulation Application in Healthcare
  • 60.
    Operation Research usingDES (Discrete Event Simulation) 1. Formulate the research question 2. Define the operational process (workflow) 3. Collect date to fit distribution 4. Construct and validate the model 5. Run experiment ©2011 MFMER | 3123886-60
  • 62.
    Crit Care Med2007 Vol. 35, No. 11 Critical Importance of Timing
  • 63.
    Spain Study Ferrer R,et al. Improvement in process of care and outcome after a multicenter severe sepsis educational program in Spain. JAMA. 2008;299(19):2294-2303.
  • 64.
    Research Methodology Baseline Process IdentifyCauses of Delay Process Modeling Suggestions for Improvement Measure ImpactSensitivity Analysis Statistical Analysis Root Cause Analysis & FMEA Discrete-Event Simulation ANOVA Design of Experiment User Requirement and Scope
  • 65.
  • 66.
    Data Collection • Timeframe • Dec 2007 to June 2009 • Sample size: • 600 sepsis patients • Source of data • Sepsis QI Project (Courtesy of Dr. Afessa) • EMR: ICU Datamart • Direct observations: CVC, fluid infusion, etc. • Expert opinions: MD, RN, RT, Pharmacist, et al • Administration database • Obstacles with data • Uncompleted dataset • Care process variation
  • 67.
    Fellow ResidentConsultant PharmacistBedsideRN Sepsis Recongnition Antibiotics/ Source Control Fluid Resuscitation Central Venous Catheterization Vesopressor Administration Inotrope Administration Transfusion Patient SepsisResuscitationGoalReached Simulation Modeling of Healthcare Delivery During Sepsis Resuscitation Dong Y, et al. Optimization of healthcare delivery during sepsis resuscitation by simulation and modeling. Simulation in Healthcare 2010;5:423.
  • 68.
    Accelerated T&X CVC Efficiency ScVO2 Monitors No CXRDelayEarly Recognition ResuscitationRecognition Sepsis Care Optimization by Discrete Event Simulation (S-CODES)
  • 69.
    Model Validation Empirical Data Model Data % Variance Duration (months)18 18 0% Total Sepsis Patients 597 600 0.5% Average number of patients/day 2.4 2.7 -1.3 % Average Cycle Time (min) 382 418 9.4 %
  • 70.
    Sepsis Resuscitation TimeReduction by Different Options Clinical Data Sepsis Resusiation Time Reducation by Different Options 29.16 26.81 7.81 137.92 16.11 55.94 0.00 30.00 60.00 90.00 120.00 150.00 Opt 1 - Early Recog Opt 2 - Quick CVC Opt 3 - No X-Ray Opt 4 - Pre Type/Cross Opt 5 - ScVO2 Monitors Opt 6 - All Time(min)
  • 71.
    DES study inclinical practices • Analyze & Visualize patient flow (Batarseh 2014) • Optimize unit bed capacity (Zhu 2012) • Forecast near-future operation status (Hoot 2009) • Study interaction between providers (Lim 2013) • Evaluate ED/EMS interaction (Stahl 2003) • Decrease inpatient boarding (Levin 2008) ©2011 MFMER | 3123886-71
  • 73.
    Recent Major Reports •Executive Office of the President President’s Council of Advisors on Science and Technology: Report To The President Better Health Care And Lower Costs: Accelerating Improvement Through Systems Engineering (May 2014) • National Science Foundation: Operations Research - A Catalyst for Engineering Grand Challenges (May 2014) • The ASQ Healthcare Division Marshall Plan: "Put Me In The Game, Coach! ” (The Quality Management Forum, Winter 2014)
  • 75.
    Simulation to improvequality and safety Constructive Virtual Live Training Assessment Research and Integration Patient Healthcare Providers Healthcare Systems
  • 76.
    ©2011 MFMER |3123886-76
  • 78.
  • 79.
    Summary • Quality andpatient safety are the driver for value based healthcare delivery • Use more simulation to • Improve provider and team skills • Improve systems performance
  • 80.
    From Mayo ClinicCenter for Innovation
  • 81.
    Healthcare Systems Modeling& Simulation Affinity Group goo.gl/PRIkog goo.gl/0r5mOs http://www.ssih.org/Interest- Groups/Healthcare-Systems-Modeling- Simulation goo.gl/7QuuQd