Bladder injuries are rare. But when present in cases of polytrauma they pose both a diagnostic as well as surgical challenge to the attending surgeon. Understanding the mechanisms underlying bladder injuries is pivotal in developing a diagnostic algorithm in order to avoid missing of any urologic injury. Once the extent and site of damage is diagnosed then prompt surgical intervention is the mainstay of treatment. The pathophysiology and management of bladder injuries is discussed in this paper.
Please find the power point on Renal and bladder stones. I tried present it on understandable way and all the contents are reviewed by experts and from very reliable references. Thank you
Bladder injuries are rare. But when present in cases of polytrauma they pose both a diagnostic as well as surgical challenge to the attending surgeon. Understanding the mechanisms underlying bladder injuries is pivotal in developing a diagnostic algorithm in order to avoid missing of any urologic injury. Once the extent and site of damage is diagnosed then prompt surgical intervention is the mainstay of treatment. The pathophysiology and management of bladder injuries is discussed in this paper.
Please find the power point on Renal and bladder stones. I tried present it on understandable way and all the contents are reviewed by experts and from very reliable references. Thank you
URETHRAL INJURY- Trauma Surgery
#surgicaleducator #babysurgeon
Dear viewers,
Greetings from “Surgical Educator”
Today I have uploaded a video on URETHRAL INJURY- one more in Trauma Surgery. I haven’t talked elaborately but have included the essential minimum an undergraduate medical student should know. I have talked about anatomy, classification, etio-pathogenesis, symptoms, signs, investigations, grading, treatment, complications, treatment algorithm and case vignettes of urethral injuries. My aim is, after watching this video all of you should be able to arrive at a correct working diagnosis of the type of urethral injury and should also be able to institute immediate treatment to the patients if there is a need. The definitive urethroplasty should be done by a Urologist. You can watch the video in the following links:
surgicaleducator.blogspot.com
youtube.com/c/surgicaleducator
Thank you for watching the video.
Types of Urethral injury, Mechanism of Urethral injury, Classification of Urethral injury, Symptoms of Urethral injury, Signs of Urethral injury,
Investigations for Urethral injury, Grading of Urethral Injury, Treatment for Urethral injury, Complications of Urethral Injury
URETHRAL INJURY- Trauma Surgery
#surgicaleducator #babysurgeon
Dear viewers,
Greetings from “Surgical Educator”
Today I have uploaded a video on URETHRAL INJURY- one more in Trauma Surgery. I haven’t talked elaborately but have included the essential minimum an undergraduate medical student should know. I have talked about anatomy, classification, etio-pathogenesis, symptoms, signs, investigations, grading, treatment, complications, treatment algorithm and case vignettes of urethral injuries. My aim is, after watching this video all of you should be able to arrive at a correct working diagnosis of the type of urethral injury and should also be able to institute immediate treatment to the patients if there is a need. The definitive urethroplasty should be done by a Urologist. You can watch the video in the following links:
surgicaleducator.blogspot.com
youtube.com/c/surgicaleducator
Thank you for watching the video.
Types of Urethral injury, Mechanism of Urethral injury, Classification of Urethral injury, Symptoms of Urethral injury, Signs of Urethral injury,
Investigations for Urethral injury, Grading of Urethral Injury, Treatment for Urethral injury, Complications of Urethral Injury
Ureters are retroperitoneal structues which run anterior to psoas muscle and cross lateral to medial.4sites are prone where ureter can be injured and its management
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
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New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
3. INTRODUCTION
• Urethral injury is a relatively uncommon
urological condition
• The management could be challenging to both
the urologist and patient
• It could affect all age groups but more
commonly males
• It is usually associated with pelvic fractures
and multiple organ injuries
4. RELEVANT ANATOMY
• Male Urethra is divided
into: Anterior and
Posterior Urethra
• Female Urethra is only
Posterior
• Blood Supply
• Nerve Supply
6. ANTERIOR URETHRAL INJURY
Blunt trauma
• Vehicular accidents
• Fall astride
• Kicks in the perineum
• Blows in the perineum from
bicycle handlebars, tops of
fences, etc.
Sexual intercourse
• Penile fractures
• Urethral intraluminal
stimulation
• Constriction bands
Penetrating trauma
• Gunshot wounds
• Stab wounds
• Dog bites
• External impalement
• Penile amputations
Constriction bands
• Paraplegia
Iatrogenic injuries
• Endoscopic
instrumentations
• Urethral catheters, dilators
7. CLINICAL FEATURES
• History of perineal or
penile trauma
• Blood at meatus
• Inability to void
• Suprapubic fullness
• Haematuria
• Haematoma
• Other associated
injuries
9. MANAGEMENT
• RUCG FINDINGS
1.Urethral contusion
2.Incomplete urethral
rupture
3.Complete urethral
rupture
• FACTORS AFFECTING
INITIAL MANAGEMENT
1.Mechanism of injury
2.Extent of injury
3.Co-injuries
4.Surgeon’s familiarity
with proposed
procedure
10. MANAGEMENT
• Urethral Contusion – Maintain suprapubic
catheter or gentle urethral catheterization for
2 weeks and remove subsequently
• Incomplete Urethral Rupture – Blunt or
Penetrating
• Complete Urethral Rupture – Blunt or
Penetrating
(McAninch and Armenakas)
11. MANAGEMENT
• BLUNT
• Maintain Suprapubic or
Urethral catheter for 3-4
wks to allow for urethral
healing
• Do a MCUG + RUG to assess
for any stricture and
manage accordingly
• For Complete Disruption,
MCUG + RUG after 3-6
months and manage the
stricture
• PENETRATING
• For incomplete rupture,
Primary urethral suturing
with creation of a water-
tight, tension-free repair
• For complete rupture,
repair over a urethral stent
if possible
• Repeat MCUG after 2 weeks
• If defect is large, two stage
urethral repair after at least
3 months
13. POSTERIOR URETHRAL INJURY
• Posterior urethra =
Membranous + Prostatic
urethra
• The apex of the prostate is
anchored to the pubic
symphysis by the pubo-
prostatic ligament anteriorly
• Membranous urethra is
fixed to the ischiopubic rami
by the urogenital diaphragm
• Blunt injuries >90%
RTA,Industrial accident,
Construction site accident,
Falling from height
• Penetrating
injuries;uncommon
• Approx 100% of
membranous urethra injury
following blunt trauma have
associated pelvic fracture.
• 5-10% of pelvic fracture
have associated urethral
injury
14. MECHANISM OF INJURY
• Upward displacement of the hemipelvis & pubic
symphysis
• Bilateral superior & inferior rami # with a displaced
central floating segment
• Pubic symphysis diastasis with rupture of
puboprostatic ligament
• Direct laceration by a sharp bony spicule
15.
16. CLINICAL FEATURES
• Meatal bleeding / Blood at introitus (37-93%)
• Inability to void
• Distended bladder
• High riding prostate (not a reliable indicator)
• Perineal/Vulva haematoma
• Inability to walk
• Features of shock
17. CLINICAL FEATURES
• BRIEF HISTORY
• GENERAL EXAMINATION
• RESUSCITATION
• SUPRAPUBIC CYSTOSTOMY / URETHRAL
CATHETERIZATION
• ANTIBIOTICS
• ANALGESICS
• INVESTIGATION
Retrograde urethrogram +/- mcug
18. • OTHER INVESTIGATIONS
• ABDOMINOPELVIC USS
• COMPUTED TOMOGRAPHY (CT)
• MAGNETIC RESONANCE IMAGING (MRI)
• URETHROSCOPY esp female urethral injuries
19. COLAPINTO & McCALLUM
• Type 1: Rupture of the puboprostatic ligaments and surrounding
periprostatic hematoma stretch the membranous urethra without
rupture
• Type 2: Partial or complete rupture of the membranous urethra
above the urogenital diaphragm or perineal membrane. On
urethrography, contrast material is seen extravasating above the
perineal membrane into the pelvis
• Type 3: Partial or complete rupture of the membranous urethra
with disruption of the urogenital diaphragm. Contrast extravasates
both into the pelvis and out into the perineum
• Type 4: Bladder neck injury with extension into the urethra.
• Type 4a: Extraperitoneal bladder rupture at the bladder base with
periurethral extravasation, simulating a Type 4 injury.
• Type 5: Pure anterior urethral injury
20. AMERICAN ASSOCIATION FOR
SURGEON OF TRAUMA (AAST)
• GRADE 1 - CONTUSION
NORMAL RUCG
• GRADE II - STRETCH INJURY
URETHRAL ELONGATION,NO EXTRAVASATION
• GRADE III - PARTIAL DISTRUPTION
EXTRAVASATION + CONTRAST IN BLADDER
• GRADE IV - COMPLETE DISTRUPTION
NO CONTRAST IN BLADDER, URETHRAL SEPARATION <2cm
• GRADE V - COMPLETE DISTRUPTION
URETHRAL SEPARATION >2cm or EXTENSION INTO THE PROSTATE,
BLADDER NECK, OR VAGINA
21. MANAGEMENT
• Partial tears of the posterior urethra can be
managed in most cases with a suprapubic or
urethral catheter
• Repeat retrograde urethrography at 2-week
intervals until healing has occurred
• They may heal without significant scarring or
obstruction if managed by diversion alone
• Any residual or subsequent stricture can be
managed with urethral dilation or optical
urethrotomy, if short and flimsy, or by
anastomotic urethroplasty if denser
23. PRIMARY REALIGNMENT
• RATIONALE
1. Injury may heal without stricture at all
2. Injury may heal with mild stricture treatable
by DVIU or bouginage
3. Eases the difficulty of urethroplasty later
24. PRIMARY REALIGNMENT
• OPEN – for concomitant bladder neck or rectal injuries
• ENDOSCOPIC – Opions are
Simple passage of a catheter across the defect
Endoscopically assisted catheter realignment using flexible,
rigid endoscopes and biplanar fluoroscopy
Use of interlocking sounds (“railroading”) or magnetic
catheters to place the catheter
Pelvic hematoma evacuation and dissection of the prostatic
apex (with or without suture anastomosis) over a catheter
Catheter traction or perineal traction sutures to pull the
prostate back to its normal location
26. CONCLUSION
• Urethral injury still remain of the most
commonly mismanaged urological condition
• Constant reminder to colleagues about the
presentation
• Need for initial proper assessment and
subsequent management