This document discusses guidelines and considerations for providing anaesthesia services in non-operating room areas (NORA) such as for MRI/CT scans. It notes special challenges in NORA including limited space, equipment issues, and unfamiliar environments. Key guidelines are outlined such as having proper patient monitoring, emergency equipment, and following pre-procedure evaluations. Specific anaesthetic drugs that can be used for moderate sedation are discussed, including propofol, benzodiazepines, dexmedetomidine, and ketamine. Hazards in the MRI environment like magnetic fields, acoustic noise, and restricted access are summarized. The document stresses the importance of patient safety, standards of care, and proper planning for NORA cases.
Basic principles of MRI machine. effect of mri on monitoring equipments in anesthesia. modes of anesthesia for MRI procedures.safety measures to be taken for MRI procedures
Basic principles of MRI machine. effect of mri on monitoring equipments in anesthesia. modes of anesthesia for MRI procedures.safety measures to be taken for MRI procedures
Ambulatory Anesthesia and Non–Operating Room Anesthesia (NORA)Saeid Safari
GUIDELINES FOR AMBULATORY ANESTHESIA AND SURGERY (American Society of Anesthesiologists)
GUIDELINES FOR AMBULATORY ANESTHESIA AND SURGERY
Non–Operating Room Anesthesia (NORA)
Hypothyroidism and hyperthyroidism have significant clinical effects. Both should be optimized. Anesthesia providers should be able to diagnose and manage.
Ambulatory Anesthesia and Non–Operating Room Anesthesia (NORA)Saeid Safari
GUIDELINES FOR AMBULATORY ANESTHESIA AND SURGERY (American Society of Anesthesiologists)
GUIDELINES FOR AMBULATORY ANESTHESIA AND SURGERY
Non–Operating Room Anesthesia (NORA)
Hypothyroidism and hyperthyroidism have significant clinical effects. Both should be optimized. Anesthesia providers should be able to diagnose and manage.
Short description about awake craniotomy, its indications, contraindications, complications,various techniques of providing awake craniotomy and drugs used.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
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1. MAC FOR MRI/CT
SCAN
DR TSHERING P. BHUTIA,
SENIOR RESIDENT,
DEPARTMENT OF ANAESTHESIOLOGY ,
SIKKIM MANIPAL INSTITUTE OF MEDICAL
SCIENCE,
GANGTOK,SIKKIM.
2. Special problem of NORA
Limited working place
limited access to the patient
Electrical interference with monitors and
phones, lighting and temperature inadequacy,
Use of outdated ,old equipment
Unfamiliar environment that are far removed
from surgical suites.
Lack of skilled assistant, drugs and supplies.
3. Basic principles for NORA
PATIENT
1. Comorbidity
2. Airway
3. Fasting
status
4. Monitoring
ENVIROMENT
AL
1. Anaesthesia
equipment
2. Emergency
equipment
3. Magnetic/rad
iation
hazards
PROCEDURE
1. Duration
2. Level of
discomfort
3. Patient
position
4. Surgical
support.
4. ASA GUIDELINES
( ASA October 17, 2018)
1. Reliable O2 source with
backup
2. Suction apparatus
3. Waste gas scavenging
4. Adequate monitoring
equipment
5. Safe electrical outlets
6. Adequate
illumination,battery
backup
7. Sufficient space for
anaesthesia
personnel,equipments
8. Emergency
cart,defibrillator,drugs
9. Reliabe means of two-
way communicaton
10. Applicable facility and
safety codes met
11. Appropiate post
anaesthesia
management.
5. Anaphylaxis pack
1. Adrenaline 1:1000 for IM injection
2. Chlorpheniramine
3. Hydrocortisone
4. Blood tubes for tryptase to confirm diagnosis.
5. Readily available clearly displayed
emergency response plans(wall charts)for
cardiovascular collapse,over
sadeation,anaphylaxis.
7. 1) A strong magnetic field
Local heating and may interfere with monitoring
equipment.
Movement of blood around the body will also
result in the generation of electric potentials and
current causing symptoms such as nausea and
vertigo.
Current recommendations suggest that an
average exposure of 200mT over any 8-hour
period should not be exceeded by healthcare
personnel.
8. 2) The projectile effect
All ferromagnetic items must be excluded from
the area of magnet.Eg-O2 tanks,watches,mobile
All anaesthesia equipment must be compatible
with the magnet in use.
Patients must be free of implants that could
interact with magnets such as
pacemakers,vascular clips,ICDs,infusion pumps,
cochlear implants,intra-ocular metallic foreign
bodies
9. 3) Implants and foreign bodies
Implanted ferromagnetic objects may also heat
up significantly during the MR examination
causing local tissue damage-ABSOLUTE
CONTRAINDICATION.
Most modern patient implants, including metal
prostheses, are non-ferromagnetic.
General surgical clips, artificial heart valves and
sternal wires are usually deemed safe since they
are fixed by fibrous tissue
10. 4) Equipment and monitoring
issues
MRI safe or MRI compatible ??
longer ETCO2 sampling lines
All alarms should be visual.
Pulse oximeter cables should be insulated and
placed as far from the scanner as possible.
Non-invasive blood pressure monitoring is
possible if connectors are changed to plastic.
11. 5) Restricted access of the
environment
Patient is effectively enclosed within a narrow
tube to which access is extremely limited
Obese patient may not fit.
Claustrophobia…..
Newer designs include open C shaped magnets
that are less claustrophobic.
Arrangements and backup plan for any critical
incident during MRI should be available.
12. 6) High level acoustic noise
Noise levels above the safe level of 85 decibels
can be produced during MRI due to the rapid
switching of the gradient coils
Wearing earplugs to be made mandatory for staff
and patient, whether anaesthetized or not
Sound alarms to be accompanied with visual
alarms
13. 7)Hazards of MRI during
pregnancy
The MRI unit may pose hazards to the
developing foetus,including exposure to strong
magnetic fields, high noise levels and
unscavenged anaesthetic gases.
Currently recommended that pregnant women
should ideally not be scanned during the first
trimester of pregnancy
Pregnant staff working within the MRI unit should
be advised of the risks.
14. 8) Contrast agents
Minor side effects including nausea, vomiting and
pain on injection.
Rare complications called nephrogenic systemic
fibrosis or nephrogenic fibrosing dermopathy, seen
in association with renal impairment
Anaphylactoid reaction reported.
15. 9) Maintenance of body
temperature
A theoretical problem during sedation or
anaesthesia of infants and neonates for MRI is
the maintenance of body temperature within this
cooled environment.
Passive heat loss should be prevented by
minimizing exposure and by returning the infant
to a warm environment as soon as possible
Radiofrequency radiation produced by the MR
scanner,absorbed by the patient causes an
increase in body temperature, suggesting that
active heating is unnecessary and may in fact
16. Zones in MRI
1. Zone One -accessible to
the general public
2. Zone Two- acts as a
buffer between Zone One
and the more restrictive
Zone Three. Here,
patients are under the
general supervision of
MR personnel
3. Zone Three- should be
restricted by a physical
barrier. Only approved
MR personnel and
questionnaire and
interview are allowed
inside Zone Three.The
MR control room and/or
computer room are
located within Zone Three
4. Zone four-is strictly the
area within the walls of
the MR scanner room,
sometimes called the
magnet room. Access into
the MR scanner room
should only be available
by passing through Zone
17.
18. What is acceptable and what is
not.
No matter what type or level of anaesthesia care is
provided,an anaesthesia machine should be
present or readily available in all NORA
locations because conversion to general
anaesthesia is always a possibility.
Adequate prepocedure and postprocedure
space should be available .
It is certainly the standard of care that an
anaesthesiologist should be available during
recovery period.
19. PREPROCEDURAL
EVALUATION-Additional
considerations.
1. Preprocedure evaluation is a MUST regardless of
where/who is performing the procedure.
2. Assessment of ASA status
3. Factors that may indicate sensitivity to sedation
eg.sleep apnea,COPD,smoking,alcohol
abuse,obesity and renal/hepatic impairment should
be identified.
4. Drug history/allergies
5. Anaesthetic history/airway assessment.
6. Positioning-Patient should be assesed to ensure
20. NPO GUIDELINES
2HRS-CLEAR FLUID
4HRS-BREAST MILK
6HRS-A LIGHT MEAL,INFANT FORMULA,NON
HUMAN MILK
8HRS-FULL MEAL
Timely prepocedure evaluation and enforcement of
clear standards for NPO can prevent mishaps and
unnecesary cancelations.
Educating the proceduralist and their staff is
required.
21. Consent /Safety checklist
Preprocedure baseline
parameters(HR,BP,SpO2,RR,Chest)should be
documented.
Ht/wt measurement-dose calculation.
Advice on regular medications.
Reliable IV Cannula
BEFORE EVERY CASE FORMAL
CONFIRMATION THAT ALL APPROPIATE
EQUIPMENT IS AVAILABLE/WORKING & ITS
LOCATION.
22. Monitoring Considerations
1. ECG
‐rapidly changing magnetic fields produce artifact, ST and
Twave abnormalities, and may mimic arrhythmias,if ECG
wires are in a loop, a the magnetic field may heat the wires
and leads, thus leading to thermal injury (antenna coupling
effect)
2. Pulse oximetry
like ECG wires, the antenna effect may produce thermal injury
3. Capnography
‐increased length of sampling line may have prolonged time
delay
4. Blood pressure
‐need for plastic components
5. Temparature
23. During procedure patient care
Intravenous(IV)access should be maintained.
Record of all the drugs given with dose,time &
route.
Maintain normothermia
Monitoring vitals should be recorded on a chart.
Prevent pressure and position related injury
Patient may be transferred to the recovery area
with same level of care and staffing.
Proper post procedure orders and time to
discharge should be recorded.
24. Defination of level of sedation
MINIMAL
SEDATION
(ANXIOLYSIS)
MODERATE
SEDATION(CON
SIOUCS
SEDATION)
DEEP
SEDATION
GENERAL
ANAESTHESIA
RESPONSIV
ENESS
NORMAL
RESPONSE TO
VERBAL
STIMULATION
PURPOSEFUL
RESPONSE TO
VERBAL/TACTIL
E STIMULATION
PURPOSEFUL
RESPONSE
TO
REPEATED/PAI
NFUL STIMULI
UNAROUSABL
E EVEN TO
PAINFUL
STIMULI
AIRWAY UNAFFECTED NO
INTERVENTION
REQUIRED
INTERVENTIO
N MAY BE
REQUIRED
INTERVENTIO
N USUALLY
REQUIRED
SPONTANE
OUS
VENTILATIO
N
UNAFFECTED ADEQUATE MAY BE
IMPAIRED/ASI
STANCE MAY
BE REQUIRED
FREQUENTLY
IMPAIRED/ASS
ISTANCE
REQUIRED
CARDIOVAS UNAFFECTED USUALLY USUALLY MAY BE
25. Goals of MAC
1. Maintain patient safety and sense of well
being
2. Alleviate pain and minimize discomfort
3. Minimize psychological response-anxiolysis,
analgesia, amnesia
4. To return to the prepocedural state
5. Safe discharge
6. Drugs should have rapid/complete recovery
7. Minimal nausea and vomiting
26. Drug interactions in MAC
1. No single IV anaesthetic drug can provide all
the components of MAC.
2. Combination of drug act synergistically.eg-
opoid-BZD achieve-
hypnosis,amnesia,analgesia
3. Continous infusion are superior to intermittant
bolus-less fluctuation in drug conc..prompt
recovery.
27. Propofol
1. Short context sensitive half life
2. Doesn’t possess analgesic property-so
LA/opoid
3. Antiemetic property
4. Infusion of 25-50mcg/kg/min
5. Remifentanyl 0.01-0.05mcg/kg/min
6. OR alfentanyl infusion of 0.2-0.4 mcg/kg/min
31. CLONIDINE &
DEXMEDETOMIDINE
Both are alpha2
agonist.
Sedative,analgesic and
sympatholytic property
Dexmedetomidine is
more selective to
alpha2
receptor.alpha1:alpha2
1:1600 as compared to
clonidine which has
selctivity ratio of 1:200
Shorter half life 2-3hrs
as compared to
clonidine which has12-
24hrs.
Decreased shivering
Side effects-
hypotension,bradycardi
a
34. Sedative and protective airway
reflexes
Complete recovery of swallowing reflex occurs
~15min after return of consciosness from
Propofol anesthesia
It is depressed for upto 2hrs after midazolam.
Hypoventilation secondary to opiod-hence
supplemental O2 is required .
35. IT IS IMPORTANT TO REMEMBER THAT
THE SAME BASIC STANDARDS OF
ANAESTHESIA CARE NEED TO BE MET
REGARDLESS OF THE LOCATION.
-THANK YOU.