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Lyme disease, caused by the spirochete Borrelia burgdorferi and transmitted through tick bites, is the most common vector-borne illness in the U.S., particularly affecting the upper midwestern and northeastern regions. In 2015, 95% of reported cases were concentrated in 14 states, with ongoing concerns in areas like Minnesota and Wisconsin. Research initiatives are underway at various universities to address treatment and eradication of the disease.







